Click here to switch to the map view.

The map label for this gene is ucpA [C]

Identifier: 124025302

GI number: 124025302

Start: 537507

End: 538229

Strand: Direct

Name: ucpA [C]

Synonym: NATL1_05911

Alternate gene names: 124025302

Gene position: 537507-538229 (Clockwise)

Preceding gene: 124025301

Following gene: 124025304

Centisome position: 28.82

GC content: 36.79

Gene sequence:

>723_bases
TTGCTTTTAACTTTCTTGTCAACAGTATTAATTACGGGCGCTTCTAGAGGAATTGGGAGAGCAACTGCTAAAGCTTTTGC
TGATTCTGGATGGGATTTACTACTTTTAGCTAGGTCTGAAGGAGCTCTAGCAAGACTTGTAGAAGAAATTGATAACAAAA
AAGTTAAGGTTTTCTACAAATCTATTGATTTAAATAATCCTAAAAATATATCTAAGGGAATAGTTGAATTAATGAATAAT
GGTTTGATTCCCTCAGTTCTAATTAATAATGCTGGAGTTGCTTGGACTGGAGATCTTTTATCAATGCCCCTTGAAAAATG
GGAATGGATCATGCAAATGAATCTCACCAGCATCTTTCAGGTTTGCTCTGAGGTGGTTCCTTTAATGAGAAAAAAAGGAG
GATTAGTTATCAACGTTAGTAGTCATGCTTCTCGAAATGTTTTTCCACAATGGGGAGCCTATTGTGTTTCCAAAGCAGCT
CTAGCAAGTTTTACCAAATGCTTAGCAGAAGAAGAACGTAAGAATTTCATACGAGCATGCACACTTACTCTTGGATCAGT
AAATTCATCTCTTTGGGATTCTGATAGCGTTGGGATGCAATTTGATAGAGATGCGATGCTTTCAGTTGATCAAGTTGCAT
GTGAACTTTTACATCTTGCTAGTCAACCAACTAATCAAATTATAGAGGATGTAACTTTGATGCCATCTGCCGGAGCCTTT
TAA

Upstream 100 bases:

>100_bases
ATGAATTGAGAAACAATAGATATTCTAAATTTAGAAAAATGGGAAAATATTTGGAATCTCAGTCTATCGAAAGTGAAATT
TCAGTTTAAAGTTTTAATGT

Downstream 100 bases:

>100_bases
TTTTGTTCTCTTATTTCGCGAACAAGAGATGCAACTTTCTTAAGATCTTTAATACCTGGAGATATCTCTAGTCGGCTAGA
TGCATCAATACCATCAGGTC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MLLTFLSTVLITGASRGIGRATAKAFADSGWDLLLLARSEGALARLVEEIDNKKVKVFYKSIDLNNPKNISKGIVELMNN
GLIPSVLINNAGVAWTGDLLSMPLEKWEWIMQMNLTSIFQVCSEVVPLMRKKGGLVINVSSHASRNVFPQWGAYCVSKAA
LASFTKCLAEEERKNFIRACTLTLGSVNSSLWDSDSVGMQFDRDAMLSVDQVACELLHLASQPTNQIIEDVTLMPSAGAF

Sequences:

>Translated_240_residues
MLLTFLSTVLITGASRGIGRATAKAFADSGWDLLLLARSEGALARLVEEIDNKKVKVFYKSIDLNNPKNISKGIVELMNN
GLIPSVLINNAGVAWTGDLLSMPLEKWEWIMQMNLTSIFQVCSEVVPLMRKKGGLVINVSSHASRNVFPQWGAYCVSKAA
LASFTKCLAEEERKNFIRACTLTLGSVNSSLWDSDSVGMQFDRDAMLSVDQVACELLHLASQPTNQIIEDVTLMPSAGAF
>Mature_240_residues
MLLTFLSTVLITGASRGIGRATAKAFADSGWDLLLLARSEGALARLVEEIDNKKVKVFYKSIDLNNPKNISKGIVELMNN
GLIPSVLINNAGVAWTGDLLSMPLEKWEWIMQMNLTSIFQVCSEVVPLMRKKGGLVINVSSHASRNVFPQWGAYCVSKAA
LASFTKCLAEEERKNFIRACTLTLGSVNSSLWDSDSVGMQFDRDAMLSVDQVACELLHLASQPTNQIIEDVTLMPSAGAF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=192, Percent_Identity=25.5208333333333, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI142976729, Length=164, Percent_Identity=32.3170731707317, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI109715829, Length=243, Percent_Identity=25.5144032921811, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI7705925, Length=190, Percent_Identity=28.9473684210526, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI87082100, Length=189, Percent_Identity=30.1587301587302, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787335, Length=163, Percent_Identity=29.4478527607362, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI2367175, Length=205, Percent_Identity=27.8048780487805, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788459, Length=197, Percent_Identity=24.8730964467005, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI87082160, Length=168, Percent_Identity=27.9761904761905, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=179, Percent_Identity=34.0782122905028, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=180, Percent_Identity=32.7777777777778, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=207, Percent_Identity=29.951690821256, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=205, Percent_Identity=29.7560975609756, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=230, Percent_Identity=26.9565217391304, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=26.0162601626016, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=199, Percent_Identity=30.1507537688442, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=184, Percent_Identity=25.5434782608696, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=230, Percent_Identity=26.5217391304348, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=245, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322226, Length=188, Percent_Identity=31.9148936170213, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6322227, Length=192, Percent_Identity=28.125, Blast_Score=69, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21357041, Length=187, Percent_Identity=32.620320855615, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI23397609, Length=199, Percent_Identity=33.1658291457286, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28571526, Length=175, Percent_Identity=32.5714285714286, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24644339, Length=173, Percent_Identity=34.6820809248555, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24643142, Length=172, Percent_Identity=32.5581395348837, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116007236, Length=241, Percent_Identity=24.0663900414938, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24639444, Length=186, Percent_Identity=25.2688172043011, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24584748, Length=166, Percent_Identity=28.9156626506024, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161076933, Length=166, Percent_Identity=28.9156626506024, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281364494, Length=245, Percent_Identity=24.0816326530612, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21358495, Length=188, Percent_Identity=27.1276595744681, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24641232, Length=240, Percent_Identity=26.6666666666667, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26216; Mature: 26216

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTFLSTVLITGASRGIGRATAKAFADSGWDLLLLARSEGALARLVEEIDNKKVKVFYK
CHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCEEEEEEE
SIDLNNPKNISKGIVELMNNGLIPSVLINNAGVAWTGDLLSMPLEKWEWIMQMNLTSIFQ
ECCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCEEECHHHHCCHHHHHHHHHHHHHHHHH
VCSEVVPLMRKKGGLVINVSSHASRNVFPQWGAYCVSKAALASFTKCLAEEERKNFIRAC
HHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLTLGSVNSSLWDSDSVGMQFDRDAMLSVDQVACELLHLASQPTNQIIEDVTLMPSAGAF
HHHHHCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLLTFLSTVLITGASRGIGRATAKAFADSGWDLLLLARSEGALARLVEEIDNKKVKVFYK
CHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCEEEEEEE
SIDLNNPKNISKGIVELMNNGLIPSVLINNAGVAWTGDLLSMPLEKWEWIMQMNLTSIFQ
ECCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCEEECHHHHCCHHHHHHHHHHHHHHHHH
VCSEVVPLMRKKGGLVINVSSHASRNVFPQWGAYCVSKAALASFTKCLAEEERKNFIRAC
HHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLTLGSVNSSLWDSDSVGMQFDRDAMLSVDQVACELLHLASQPTNQIIEDVTLMPSAGAF
HHHHHCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA