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The map label for this gene is accA

Identifier: 124025301

GI number: 124025301

Start: 536506

End: 537495

Strand: Direct

Name: accA

Synonym: NATL1_05901

Alternate gene names: 124025301

Gene position: 536506-537495 (Clockwise)

Preceding gene: 124025300

Following gene: 124025302

Centisome position: 28.77

GC content: 41.72

Gene sequence:

>990_bases
ATGGCTAGACGTTTTCTCCTCGAATTTGAAAAACCTCTTGTTGAATTAGAGAATCAGATTGATCAAATCAGAGAATTAGC
AAGAGATTCAGAAGTTGATGTAAGTCAGCAACTTTTGCAATTAGAAACACTTGCAGCACGAAGGCGCGAAGAAATATTTC
ATGCACTTACTCCAGCTCAGAAGATTCAAGTAGCTAGGCACCCCCAAAGGCCTAGCACACTCGATTACATACAGATGTTT
TGTGATGATTGGGTTGAATTACATGGAGACAGGAATGGAACTGATGATCAAGCTCTAATAGGAGGGTTAGCTCGAATAGG
TGAAAAATCCGTCCTTTTAATTGGACAACAAAAAGGTAGAGATACAAAAGAGAATGTTGCAAGAAACTTTGGCATGGCAA
AACCTGGAGGCTACAGGAAGGCTTTGAGGCTGATGGACCATGCCGATCGCTTCAATCTGCCAATCATCTCTTTCATAGAT
ACTCCTGGAGCTTACGCAGGGCTCATAGCAGAAGAACAAGGACAAGGAGAAGCAATCGCAGTGAATTTACGAGAAATGTT
TAGGCTTACAGTTCCAATAATTGCAACTGTAATAGGGGAAGGTGGCTCTGGTGGCGCATTGGGGATAGGCGTCGCAGACA
GGTTACTTATGTTTGAACATAGTGTTTACACAGTTGCAAGCCCTGAAGCTTGTGCTTCGATTCTATGGAGGGATGCTGGC
AAGGCTCCGGAAGCAGCTTCAGCATTAAAAATCACTGGACCTGATCTTATGAAGTTAGGAATTGTTGATGAGGTACTAAA
AGAGCCTTCTGGGGGGAATAATTGGGCCCCGCTTCAGGCTGGAGATACTTTGAAAAATGCCCTTGAGAAGCATTTATCCG
AATTATTGGCTTTATCCCCTGATGAATTGAGAAACAATAGATATTCTAAATTTAGAAAAATGGGAAAATATTTGGAATCT
CAGTCTATCGAAAGTGAAATTTCAGTTTAA

Upstream 100 bases:

>100_bases
ATTTCATCGGTAAGGCTTCTGAAAGGCACGGGTTTTCGGCTGTTGGTTTGAAATCAAATATTCAGACATTAACCGTCTGA
ACATTTGGTTACTTTTATTT

Downstream 100 bases:

>100_bases
AGTTTTAATGTTTGCTTTTAACTTTCTTGTCAACAGTATTAATTACGGGCGCTTCTAGAGGAATTGGGAGAGCAACTGCT
AAAGCTTTTGCTGATTCTGG

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MARRFLLEFEKPLVELENQIDQIRELARDSEVDVSQQLLQLETLAARRREEIFHALTPAQKIQVARHPQRPSTLDYIQMF
CDDWVELHGDRNGTDDQALIGGLARIGEKSVLLIGQQKGRDTKENVARNFGMAKPGGYRKALRLMDHADRFNLPIISFID
TPGAYAGLIAEEQGQGEAIAVNLREMFRLTVPIIATVIGEGGSGGALGIGVADRLLMFEHSVYTVASPEACASILWRDAG
KAPEAASALKITGPDLMKLGIVDEVLKEPSGGNNWAPLQAGDTLKNALEKHLSELLALSPDELRNNRYSKFRKMGKYLES
QSIESEISV

Sequences:

>Translated_329_residues
MARRFLLEFEKPLVELENQIDQIRELARDSEVDVSQQLLQLETLAARRREEIFHALTPAQKIQVARHPQRPSTLDYIQMF
CDDWVELHGDRNGTDDQALIGGLARIGEKSVLLIGQQKGRDTKENVARNFGMAKPGGYRKALRLMDHADRFNLPIISFID
TPGAYAGLIAEEQGQGEAIAVNLREMFRLTVPIIATVIGEGGSGGALGIGVADRLLMFEHSVYTVASPEACASILWRDAG
KAPEAASALKITGPDLMKLGIVDEVLKEPSGGNNWAPLQAGDTLKNALEKHLSELLALSPDELRNNRYSKFRKMGKYLES
QSIESEISV
>Mature_328_residues
ARRFLLEFEKPLVELENQIDQIRELARDSEVDVSQQLLQLETLAARRREEIFHALTPAQKIQVARHPQRPSTLDYIQMFC
DDWVELHGDRNGTDDQALIGGLARIGEKSVLLIGQQKGRDTKENVARNFGMAKPGGYRKALRLMDHADRFNLPIISFIDT
PGAYAGLIAEEQGQGEAIAVNLREMFRLTVPIIATVIGEGGSGGALGIGVADRLLMFEHSVYTVASPEACASILWRDAGK
APEAASALKITGPDLMKLGIVDEVLKEPSGGNNWAPLQAGDTLKNALEKHLSELLALSPDELRNNRYSKFRKMGKYLESQ
SIESEISV

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=313, Percent_Identity=50.1597444089457, Blast_Score=317, Evalue=1e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_PROM1 (A2C0Z2)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001014417.1
- ProteinModelPortal:   A2C0Z2
- SMR:   A2C0Z2
- STRING:   A2C0Z2
- GeneID:   4779922
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_05901
- eggNOG:   COG0825
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- ProtClustDB:   PRK05724
- BioCyc:   PMAR167555:NATL1_05901-MONOMER
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 36328; Mature: 36197

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARRFLLEFEKPLVELENQIDQIRELARDSEVDVSQQLLQLETLAARRREEIFHALTPAQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHH
KIQVARHPQRPSTLDYIQMFCDDWVELHGDRNGTDDQALIGGLARIGEKSVLLIGQQKGR
HHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCC
DTKENVARNFGMAKPGGYRKALRLMDHADRFNLPIISFIDTPGAYAGLIAEEQGQGEAIA
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHEECCCCCCCEEE
VNLREMFRLTVPIIATVIGEGGSGGALGIGVADRLLMFEHSVYTVASPEACASILWRDAG
EEHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHCC
KAPEAASALKITGPDLMKLGIVDEVLKEPSGGNNWAPLQAGDTLKNALEKHLSELLALSP
CCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCH
DELRNNRYSKFRKMGKYLESQSIESEISV
HHHHHHHHHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure 
ARRFLLEFEKPLVELENQIDQIRELARDSEVDVSQQLLQLETLAARRREEIFHALTPAQ
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHH
KIQVARHPQRPSTLDYIQMFCDDWVELHGDRNGTDDQALIGGLARIGEKSVLLIGQQKGR
HHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCC
DTKENVARNFGMAKPGGYRKALRLMDHADRFNLPIISFIDTPGAYAGLIAEEQGQGEAIA
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHEECCCCCCCEEE
VNLREMFRLTVPIIATVIGEGGSGGALGIGVADRLLMFEHSVYTVASPEACASILWRDAG
EEHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHCC
KAPEAASALKITGPDLMKLGIVDEVLKEPSGGNNWAPLQAGDTLKNALEKHLSELLALSP
CCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCH
DELRNNRYSKFRKMGKYLESQSIESEISV
HHHHHHHHHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA