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The map label for this gene is cobO [H]

Identifier: 124025291

GI number: 124025291

Start: 525639

End: 526331

Strand: Reverse

Name: cobO [H]

Synonym: NATL1_05801

Alternate gene names: 124025291

Gene position: 526331-525639 (Counterclockwise)

Preceding gene: 124025292

Following gene: 124025290

Centisome position: 28.23

GC content: 32.9

Gene sequence:

>693_bases
ATGAAAAATAAAATCACTAAAGAGGATTCAAGACTTAATAAGCTAGATAAGAGTGCAGAAAAAATAGGAATGGGTGGTAA
TTTAATACCGAATATCACCGAAGAAAAGTATAAAGAACGAATGCAAAAGAGAAAAGAAGTTCAAACACAAAGATTAAAAG
AAAGAAAAAAAGAAAAAGGTCTAATAATAGTTAATACAGGTCAAGGTAAAGGTAAAACTACAGCTGCTCTTGGGATGGGA
TTAAGAACTATTGGTCATAACCACAATGTTGCAATAATTCAATTTATCAAAGGGGGATGGGAACCAGGTGAGTCATTAGC
TTTCAAAATATTTGGGGATAAGTTAAAGTTTCATGCATGTGGGGAAGGGTTCACATGGGAAACACAAGATAGAAATAGAG
ATATAAATTTAGTCAAGTCAAGCTGGAGAAAGGCGGTCTCATATATTAAAGACCCAAATTATAAACTTATAATTTTAGAC
GAGATCATTGTTGCAATAAAACTTGGATATATTGATGAAGATGAAATTATAAATGGTATAAATTTGCGTCCAGAACTTAC
ACATATAGTCTTGACTGGAAGAGGAGCCTCAGAAAAATTAATCGATTCAGCTGATCTTGTGACAGAAATGAAATTAATCC
ACCACCCCTTTAGAGAGCAGGGAATAAAAGCACAAGAAGGAATTGAATATTAA

Upstream 100 bases:

>100_bases
TCTAGAGTCAAATATTAACAAGAAGAATAATTAATATTTATAGCTATATCTATTTTAAAAAATTATTCTTTTATTAACTT
ATTTAATTTAAGCCAAGGAA

Downstream 100 bases:

>100_bases
TTTATAGTCCTAAAAATATTTCCATCGCAAGGGATCCAATACAGATTTCAAGACGTTCTCCCAGGACTTGCTACTGTCAA
CTTGTTATGAATTTTTAATG

Product: cob(I)alamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MKNKITKEDSRLNKLDKSAEKIGMGGNLIPNITEEKYKERMQKRKEVQTQRLKERKKEKGLIIVNTGQGKGKTTAALGMG
LRTIGHNHNVAIIQFIKGGWEPGESLAFKIFGDKLKFHACGEGFTWETQDRNRDINLVKSSWRKAVSYIKDPNYKLIILD
EIIVAIKLGYIDEDEIINGINLRPELTHIVLTGRGASEKLIDSADLVTEMKLIHHPFREQGIKAQEGIEY

Sequences:

>Translated_230_residues
MKNKITKEDSRLNKLDKSAEKIGMGGNLIPNITEEKYKERMQKRKEVQTQRLKERKKEKGLIIVNTGQGKGKTTAALGMG
LRTIGHNHNVAIIQFIKGGWEPGESLAFKIFGDKLKFHACGEGFTWETQDRNRDINLVKSSWRKAVSYIKDPNYKLIILD
EIIVAIKLGYIDEDEIINGINLRPELTHIVLTGRGASEKLIDSADLVTEMKLIHHPFREQGIKAQEGIEY
>Mature_230_residues
MKNKITKEDSRLNKLDKSAEKIGMGGNLIPNITEEKYKERMQKRKEVQTQRLKERKKEKGLIIVNTGQGKGKTTAALGMG
LRTIGHNHNVAIIQFIKGGWEPGESLAFKIFGDKLKFHACGEGFTWETQDRNRDINLVKSSWRKAVSYIKDPNYKLIILD
EIIVAIKLGYIDEDEIINGINLRPELTHIVLTGRGASEKLIDSADLVTEMKLIHHPFREQGIKAQEGIEY

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=199, Percent_Identity=36.6834170854271, Blast_Score=157, Evalue=5e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 26124; Mature: 26124

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKITKEDSRLNKLDKSAEKIGMGGNLIPNITEEKYKERMQKRKEVQTQRLKERKKEKG
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LIIVNTGQGKGKTTAALGMGLRTIGHNHNVAIIQFIKGGWEPGESLAFKIFGDKLKFHAC
EEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEEEEEECCCEEEEEC
GEGFTWETQDRNRDINLVKSSWRKAVSYIKDPNYKLIILDEIIVAIKLGYIDEDEIINGI
CCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCHHHHCCCC
NLRPELTHIVLTGRGASEKLIDSADLVTEMKLIHHPFREQGIKAQEGIEY
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCC
>Mature Secondary Structure
MKNKITKEDSRLNKLDKSAEKIGMGGNLIPNITEEKYKERMQKRKEVQTQRLKERKKEKG
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LIIVNTGQGKGKTTAALGMGLRTIGHNHNVAIIQFIKGGWEPGESLAFKIFGDKLKFHAC
EEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEEEEEECCCEEEEEC
GEGFTWETQDRNRDINLVKSSWRKAVSYIKDPNYKLIILDEIIVAIKLGYIDEDEIINGI
CCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCHHHHCCCC
NLRPELTHIVLTGRGASEKLIDSADLVTEMKLIHHPFREQGIKAQEGIEY
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]