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The map label for this gene is qri7

Identifier: 124025236

GI number: 124025236

Start: 476784

End: 477854

Strand: Direct

Name: qri7

Synonym: NATL1_05251

Alternate gene names: 124025236

Gene position: 476784-477854 (Clockwise)

Preceding gene: 124025233

Following gene: 124025237

Centisome position: 25.57

GC content: 36.32

Gene sequence:

>1071_bases
ATGTCAATAATTTTATCCCTCGAAACAAGTTGTGACGAGTCTGCAGCGGCTTTGGTTTCTAATGAAAAAGGAAAAATTGA
TTTGTTAGCTAATGAAATAGCTTCACAAATTGATGAACATGCTAATTGGGGTGGTGTTGTTCCAGAAATCGCTTCAAGAA
GACATTTAGAAAACCTTCCATTTTTGATTGAAGAGGTTTTTGCAAAATCAACATTACAGATAAAAGATATAGATGCAGTA
GCCGCAACTGTTACTCCAGGATTAGCAGGATCACTGTTGGTCGGATCAATTACGGCAAGAACTTTAGCTAATTTACATCA
AATACCATTCTTAGGTATCCATCACTTGGAGGGACATCTTTCCTCAATATATTTGTCAGAAAACCATCCCAAACCCCCTT
TTTTAGTCTTATTGGTTAGTGGAGGACACACTGAATTGATAAAAGTAGATGTTAAACATAAGTATCAACGTCTTGGTAGA
AGTCATGATGATGCAGCTGGAGAAGCTTTTGATAAGGTTGCAAGACTTTTGGGACTTTCATATCCAGGGGGCCCTGCAAT
TCAAAAAATAGCTAAATCGGGAGACCCAAAAAAATTTTTATTTCCAAAAGGAAGAGTCTCTAAACCTGAAGGTGGTTTTT
ATCCATATGACTTTTCTTTTAGTGGTTTAAAAACGGCTGTATTTCGCCAGATAGAAAAAATTAGATCAGAAAATAAAAAA
TTACCAATAGAAGATATTGCTGCAAGTTTTGAATACATAGTGGCTGAAGTCTTAGTAGAGAGGAGCTTTAAATGTGCCCT
TGACCAAGGTTTAAATTCTCTTGTTTTAGTTGGAGGAGTTGCTGCAAATGTGAGATTAAGGGAAATGATGCTTGCAAAAG
CATCTAAAAATTCAATTGATATTACTCTTGCACCAATGGAATTTTGTACTGATAATGCGGCAATGATTGGGGCGGCAGCT
TTGTTAAGATTATCGTCTGAAGGCTTTAAAAGTTCAATGGAATTAGGTGTATCTGCTCGTTGGCCACTAGAAAAATCTGA
TTCACTTTATGATCCGATTCCTCCTTTTTAA

Upstream 100 bases:

>100_bases
AAAGAAGAATTGATAAAAGACGACTCATGAGTTCTGATTTTTATCTGTGCCCTGTTTTAATGGGATTTCAATACTAAACT
TAGTTGATCAATAGCTAGAA

Downstream 100 bases:

>100_bases
TTTATATTTTTAACCTTTTAATCTTTAATTATGTCTTTAAAAGAAAGTGATGAAGAAAATAAATTCACCAAGCTTGCAAG
CTCAAATGAACTTAATTCAT

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MSIILSLETSCDESAAALVSNEKGKIDLLANEIASQIDEHANWGGVVPEIASRRHLENLPFLIEEVFAKSTLQIKDIDAV
AATVTPGLAGSLLVGSITARTLANLHQIPFLGIHHLEGHLSSIYLSENHPKPPFLVLLVSGGHTELIKVDVKHKYQRLGR
SHDDAAGEAFDKVARLLGLSYPGGPAIQKIAKSGDPKKFLFPKGRVSKPEGGFYPYDFSFSGLKTAVFRQIEKIRSENKK
LPIEDIAASFEYIVAEVLVERSFKCALDQGLNSLVLVGGVAANVRLREMMLAKASKNSIDITLAPMEFCTDNAAMIGAAA
LLRLSSEGFKSSMELGVSARWPLEKSDSLYDPIPPF

Sequences:

>Translated_356_residues
MSIILSLETSCDESAAALVSNEKGKIDLLANEIASQIDEHANWGGVVPEIASRRHLENLPFLIEEVFAKSTLQIKDIDAV
AATVTPGLAGSLLVGSITARTLANLHQIPFLGIHHLEGHLSSIYLSENHPKPPFLVLLVSGGHTELIKVDVKHKYQRLGR
SHDDAAGEAFDKVARLLGLSYPGGPAIQKIAKSGDPKKFLFPKGRVSKPEGGFYPYDFSFSGLKTAVFRQIEKIRSENKK
LPIEDIAASFEYIVAEVLVERSFKCALDQGLNSLVLVGGVAANVRLREMMLAKASKNSIDITLAPMEFCTDNAAMIGAAA
LLRLSSEGFKSSMELGVSARWPLEKSDSLYDPIPPF
>Mature_355_residues
SIILSLETSCDESAAALVSNEKGKIDLLANEIASQIDEHANWGGVVPEIASRRHLENLPFLIEEVFAKSTLQIKDIDAVA
ATVTPGLAGSLLVGSITARTLANLHQIPFLGIHHLEGHLSSIYLSENHPKPPFLVLLVSGGHTELIKVDVKHKYQRLGRS
HDDAAGEAFDKVARLLGLSYPGGPAIQKIAKSGDPKKFLFPKGRVSKPEGGFYPYDFSFSGLKTAVFRQIEKIRSENKKL
PIEDIAASFEYIVAEVLVERSFKCALDQGLNSLVLVGGVAANVRLREMMLAKASKNSIDITLAPMEFCTDNAAMIGAAAL
LRLSSEGFKSSMELGVSARWPLEKSDSLYDPIPPF

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=345, Percent_Identity=35.6521739130435, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI8923380, Length=358, Percent_Identity=28.7709497206704, Blast_Score=126, Evalue=2e-29,
Organism=Escherichia coli, GI1789445, Length=341, Percent_Identity=46.0410557184751, Blast_Score=279, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI17557464, Length=334, Percent_Identity=31.7365269461078, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71995670, Length=293, Percent_Identity=30.3754266211604, Blast_Score=112, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6320099, Length=373, Percent_Identity=29.7587131367292, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6322891, Length=331, Percent_Identity=28.3987915407855, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI20129063, Length=344, Percent_Identity=30.8139534883721, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI21357207, Length=314, Percent_Identity=31.5286624203822, Blast_Score=125, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_PROM1 (A2C0S7)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001014352.1
- STRING:   A2C0S7
- GeneID:   4780725
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_05251
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- ProtClustDB:   PRK09604
- BioCyc:   PMAR167555:NATL1_05251-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 38603; Mature: 38472

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIILSLETSCDESAAALVSNEKGKIDLLANEIASQIDEHANWGGVVPEIASRRHLENLP
CEEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCH
FLIEEVFAKSTLQIKDIDAVAATVTPGLAGSLLVGSITARTLANLHQIPFLGIHHLEGHL
HHHHHHHHHCCEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCH
SSIYLSENHPKPPFLVLLVSGGHTELIKVDVKHKYQRLGRSHDDAAGEAFDKVARLLGLS
HEEEECCCCCCCCEEEEEEECCCEEEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
YPGGPAIQKIAKSGDPKKFLFPKGRVSKPEGGFYPYDFSFSGLKTAVFRQIEKIRSENKK
CCCCHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
LPIEDIAASFEYIVAEVLVERSFKCALDQGLNSLVLVGGVAANVRLREMMLAKASKNSID
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCCCEE
ITLAPMEFCTDNAAMIGAAALLRLSSEGFKSSMELGVSARWPLEKSDSLYDPIPPF
EEEECHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SIILSLETSCDESAAALVSNEKGKIDLLANEIASQIDEHANWGGVVPEIASRRHLENLP
EEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCH
FLIEEVFAKSTLQIKDIDAVAATVTPGLAGSLLVGSITARTLANLHQIPFLGIHHLEGHL
HHHHHHHHHCCEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCH
SSIYLSENHPKPPFLVLLVSGGHTELIKVDVKHKYQRLGRSHDDAAGEAFDKVARLLGLS
HEEEECCCCCCCCEEEEEEECCCEEEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
YPGGPAIQKIAKSGDPKKFLFPKGRVSKPEGGFYPYDFSFSGLKTAVFRQIEKIRSENKK
CCCCHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
LPIEDIAASFEYIVAEVLVERSFKCALDQGLNSLVLVGGVAANVRLREMMLAKASKNSID
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCCCEE
ITLAPMEFCTDNAAMIGAAALLRLSSEGFKSSMELGVSARWPLEKSDSLYDPIPPF
EEEECHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA