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The map label for this gene is ubiA [H]

Identifier: 124025222

GI number: 124025222

Start: 465556

End: 466419

Strand: Reverse

Name: ubiA [H]

Synonym: NATL1_05111

Alternate gene names: 124025222

Gene position: 466419-465556 (Counterclockwise)

Preceding gene: 124025224

Following gene: 124025221

Centisome position: 25.01

GC content: 35.19

Gene sequence:

>864_bases
ATGGGATATTATTTTCAACTTCTTAGATGGAACAAACCCAGCGGAAGATTGATACTTCTCATTCCCTCTGGCTGGTCTCT
TTGGCTAACTCCTGCAGCCCCTCCTTCTTTATTGTTTTTGGGAATAATAATTTTAGGTGGATTATTTGTAAGCGGTGCTG
GATGTATCGCTAATGATATTTGGGACAGAAAGTTTGACAAGAAGGTAATAAGAACAAAAGAGAGACCATTGGCCAATGGG
AAAGTATCTCTAAAAGCAGCATGGATACTACTAATTTTAATGTTATTTTTTAGTCTATTTATAGTTCTTTCAATCCCACA
AGAAAGTAGGAATTTATGCCTTCTCCTTTCATCCCTATCATTACCTTTTATTCTTTTATATCCATCAGCGAAAAGATGGT
TTCAATATCCCCAACTTATTCTTTCTATTTGCTGGGGTTTTTCAGTTTTAATACCTTGGGCAGCAAGTGAATCTTCTTTA
GCAGGAGTAACATTAATATATTGTTGGCTTGCAACTATTCTTTGGACTTTCGGTTTTGATACTGTTTATGCAATGGCAGA
TGAAAGTGAAGACAAAGTAATTGGTCTAAATAGCAGTGCGATCAGTCTCGGGGGAAAGTCATTAAAAACAGTTTCTCTTT
GCTACTTTTTAACTTGTATTTTTCTAGCTCTTGCTGCTTTTAAAGCAAATTTAGGATTAATATATTGGCCTTTTTGGTTG
ATAACTACTGTAGGAATGCAAAGAGAGGTTTTCTTATTAAGTTCAAAATCAAAAGGTATTAAGACTTCAGGTTTGCATTT
CAGCAATCAAGTGAGACTTGGCAGCTTATTACTTCTTGGCATGGTCTTCAGCAAGATTATTTAA

Upstream 100 bases:

>100_bases
GGTTTAACCTCAATACTCTGACACCCTCAGCACCCCATTGAGAAGACCTTATAAATCATTATCAATTTGAATTTTCGTGA
ATAATCTTCTTACCCAAAAA

Downstream 100 bases:

>100_bases
TTAATATACTGACCAAGATTCGCAAATGACTGAACCTATAAAGAAAGGAGATCATTTCCACATAGTTGCGGCAAGTTCGC
CAATAACTAAAAAAGAAGAT

Product: prenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MGYYFQLLRWNKPSGRLILLIPSGWSLWLTPAAPPSLLFLGIIILGGLFVSGAGCIANDIWDRKFDKKVIRTKERPLANG
KVSLKAAWILLILMLFFSLFIVLSIPQESRNLCLLLSSLSLPFILLYPSAKRWFQYPQLILSICWGFSVLIPWAASESSL
AGVTLIYCWLATILWTFGFDTVYAMADESEDKVIGLNSSAISLGGKSLKTVSLCYFLTCIFLALAAFKANLGLIYWPFWL
ITTVGMQREVFLLSSKSKGIKTSGLHFSNQVRLGSLLLLGMVFSKII

Sequences:

>Translated_287_residues
MGYYFQLLRWNKPSGRLILLIPSGWSLWLTPAAPPSLLFLGIIILGGLFVSGAGCIANDIWDRKFDKKVIRTKERPLANG
KVSLKAAWILLILMLFFSLFIVLSIPQESRNLCLLLSSLSLPFILLYPSAKRWFQYPQLILSICWGFSVLIPWAASESSL
AGVTLIYCWLATILWTFGFDTVYAMADESEDKVIGLNSSAISLGGKSLKTVSLCYFLTCIFLALAAFKANLGLIYWPFWL
ITTVGMQREVFLLSSKSKGIKTSGLHFSNQVRLGSLLLLGMVFSKII
>Mature_286_residues
GYYFQLLRWNKPSGRLILLIPSGWSLWLTPAAPPSLLFLGIIILGGLFVSGAGCIANDIWDRKFDKKVIRTKERPLANGK
VSLKAAWILLILMLFFSLFIVLSIPQESRNLCLLLSSLSLPFILLYPSAKRWFQYPQLILSICWGFSVLIPWAASESSLA
GVTLIYCWLATILWTFGFDTVYAMADESEDKVIGLNSSAISLGGKSLKTVSLCYFLTCIFLALAAFKANLGLIYWPFWLI
TTVGMQREVFLLSSKSKGIKTSGLHFSNQVRLGSLLLLGMVFSKII

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=203, Percent_Identity=33.4975369458128, Blast_Score=119, Evalue=5e-27,
Organism=Escherichia coli, GI1790473, Length=289, Percent_Identity=32.8719723183391, Blast_Score=129, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17553718, Length=262, Percent_Identity=32.824427480916, Blast_Score=120, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI32565247, Length=262, Percent_Identity=33.969465648855, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17553720, Length=187, Percent_Identity=36.8983957219251, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI32565243, Length=140, Percent_Identity=38.5714285714286, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32565245, Length=140, Percent_Identity=38.5714285714286, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324370, Length=239, Percent_Identity=32.6359832635983, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21355567, Length=206, Percent_Identity=34.9514563106796, Blast_Score=128, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 32010; Mature: 31879

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYYFQLLRWNKPSGRLILLIPSGWSLWLTPAAPPSLLFLGIIILGGLFVSGAGCIANDI
CCCEEEEEEECCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHH
WDRKFDKKVIRTKERPLANGKVSLKAAWILLILMLFFSLFIVLSIPQESRNLCLLLSSLS
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEEHHCC
LPFILLYPSAKRWFQYPQLILSICWGFSVLIPWAASESSLAGVTLIYCWLATILWTFGFD
CCEEEEECCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHCCH
TVYAMADESEDKVIGLNSSAISLGGKSLKTVSLCYFLTCIFLALAAFKANLGLIYWPFWL
HEEEECCCCCCCEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHH
ITTVGMQREVFLLSSKSKGIKTSGLHFSNQVRLGSLLLLGMVFSKII
HHHHCCCEEEEEEECCCCCCEECCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GYYFQLLRWNKPSGRLILLIPSGWSLWLTPAAPPSLLFLGIIILGGLFVSGAGCIANDI
CCEEEEEEECCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHH
WDRKFDKKVIRTKERPLANGKVSLKAAWILLILMLFFSLFIVLSIPQESRNLCLLLSSLS
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEEHHCC
LPFILLYPSAKRWFQYPQLILSICWGFSVLIPWAASESSLAGVTLIYCWLATILWTFGFD
CCEEEEECCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHCCH
TVYAMADESEDKVIGLNSSAISLGGKSLKTVSLCYFLTCIFLALAAFKANLGLIYWPFWL
HEEEECCCCCCCEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHH
ITTVGMQREVFLLSSKSKGIKTSGLHFSNQVRLGSLLLLGMVFSKII
HHHHCCCEEEEEEECCCCCCEECCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA