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The map label for this gene is yhdP [H]

Identifier: 124025067

GI number: 124025067

Start: 326238

End: 327506

Strand: Reverse

Name: yhdP [H]

Synonym: NATL1_03541

Alternate gene names: 124025067

Gene position: 327506-326238 (Counterclockwise)

Preceding gene: 124025070

Following gene: 124025066

Centisome position: 17.56

GC content: 35.38

Gene sequence:

>1269_bases
ATGAGTTTATTACTTCTTTGTATATTGCTTGTAATACCAGCATTTTTCAATGCAGGTCAATTTGCCATATTGCGACTTCG
TTCAACTAAGGTTCAAAGACTTGTAGAAGATGGACTACCTGGTTCCAATTCCATAATTCGTCTGCAGAAAAGGCTGAGAA
GAACCCTTTTAATAGCTGAGTTAGGAATAACTATTTCATTGATTTCAATTGGTTGGATCTGCAAAAATTTTGCAAGTCAA
TGGTGGGGAAATAATGCTTCAATTAACTATTTGTTAGATCTAGGTCTTTTTATTACTGTTGTACTTTTAGCTACTCTGAT
ATCTGGTCTGCTCCCAAAAGCACTTGTTCTTAATCAACCAGAGACTTCTGCCCTGAAATTATCGCCTCTAATTGAAGCAG
CGATAAAATGGATGTCTCCATTCCTTTCTTTGCTTGAAGGACTTGCTTTATTAATTCTTAGATTAGTTGGACTTAATACT
CAATCAGAAAGTCTTACTACAGCTGCATTCTCTGCAGGGGAATTAGAAAAATTAATTGAAACTGGTGGCGTAACTGGATT
AAAACCTGATGAAAGAAACATACTTGAAGGTGTTTTTGCTTTAAGAGATACACAAGTCAGAGAAGTAATGGTTCCCAGGT
CTGGAATGGTTACTCTTCCAAGAGAAGTTTCCTTCACTCAAATGATGGAAGAAGTTCATAAAACTCGTCATGCCAGATAC
TTAGTAATTGATGATTCACTTGATAATGTTCTTGGAGTTTTAGATTTAAGGCAACTTGCTGATCCAATAGCTAAAGGGGC
AATGCAAGCTAACTCCTCTTTGGAGCCATATATAAAGCCAGTTGTTCGTGTTTTAGAAACTTCTACTTTGGCCGAATTGC
TACCCCTAATAAAAAATGGGAATCCACTACTTTTGGTCGTTGATGAATATGGAGGAACTGAAGGATTAATAACATCAGCA
GACTTAACAGGTGAAATTGTTGGTGACGAGATTCAATTTGATAATAAAGAATCTGAGTTAAGATCTCTTGATGACTTAAA
AAAAATCTGGCTTACTTCTGGCGAAATAGAAGTAATAGAACTAAATAGAGAGCTTAACTTAAAATTGCCAGAAGCTGATG
ATCATTACACACTTGCTGGATTTGTTTTAGAAAAACTCCAAGAAATTCCAAGCTCAGGAGAAACGTTCATTCATAATGAA
ATTGTATTTGAAATTATCTCCATGAAAGGTCCAAGAATCAACAAAGTAAAAATAATCCTTCCTAAGTAA

Upstream 100 bases:

>100_bases
GTTCTCCTTTTTTGGGGGTGTAGCAATCTGGTGAATGCAGCGAACTCATAATTCGCCTTAGGCGAGTTCGATCCTCGCCA
CCCCCATAGAAAAATTATTA

Downstream 100 bases:

>100_bases
TTTATAAAACAGACTATTAATTAATAAGAAAGTAAACATGAAAAAAATTTCCAAGATCAACGAAAATATTATTCCTGTAA
AAGTTGGCGTAATAGGAATT

Product: hemolysin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MSLLLLCILLVIPAFFNAGQFAILRLRSTKVQRLVEDGLPGSNSIIRLQKRLRRTLLIAELGITISLISIGWICKNFASQ
WWGNNASINYLLDLGLFITVVLLATLISGLLPKALVLNQPETSALKLSPLIEAAIKWMSPFLSLLEGLALLILRLVGLNT
QSESLTTAAFSAGELEKLIETGGVTGLKPDERNILEGVFALRDTQVREVMVPRSGMVTLPREVSFTQMMEEVHKTRHARY
LVIDDSLDNVLGVLDLRQLADPIAKGAMQANSSLEPYIKPVVRVLETSTLAELLPLIKNGNPLLLVVDEYGGTEGLITSA
DLTGEIVGDEIQFDNKESELRSLDDLKKIWLTSGEIEVIELNRELNLKLPEADDHYTLAGFVLEKLQEIPSSGETFIHNE
IVFEIISMKGPRINKVKIILPK

Sequences:

>Translated_422_residues
MSLLLLCILLVIPAFFNAGQFAILRLRSTKVQRLVEDGLPGSNSIIRLQKRLRRTLLIAELGITISLISIGWICKNFASQ
WWGNNASINYLLDLGLFITVVLLATLISGLLPKALVLNQPETSALKLSPLIEAAIKWMSPFLSLLEGLALLILRLVGLNT
QSESLTTAAFSAGELEKLIETGGVTGLKPDERNILEGVFALRDTQVREVMVPRSGMVTLPREVSFTQMMEEVHKTRHARY
LVIDDSLDNVLGVLDLRQLADPIAKGAMQANSSLEPYIKPVVRVLETSTLAELLPLIKNGNPLLLVVDEYGGTEGLITSA
DLTGEIVGDEIQFDNKESELRSLDDLKKIWLTSGEIEVIELNRELNLKLPEADDHYTLAGFVLEKLQEIPSSGETFIHNE
IVFEIISMKGPRINKVKIILPK
>Mature_421_residues
SLLLLCILLVIPAFFNAGQFAILRLRSTKVQRLVEDGLPGSNSIIRLQKRLRRTLLIAELGITISLISIGWICKNFASQW
WGNNASINYLLDLGLFITVVLLATLISGLLPKALVLNQPETSALKLSPLIEAAIKWMSPFLSLLEGLALLILRLVGLNTQ
SESLTTAAFSAGELEKLIETGGVTGLKPDERNILEGVFALRDTQVREVMVPRSGMVTLPREVSFTQMMEEVHKTRHARYL
VIDDSLDNVLGVLDLRQLADPIAKGAMQANSSLEPYIKPVVRVLETSTLAELLPLIKNGNPLLLVVDEYGGTEGLITSAD
LTGEIVGDEIQFDNKESELRSLDDLKKIWLTSGEIEVIELNRELNLKLPEADDHYTLAGFVLEKLQEIPSSGETFIHNEI
VFEIISMKGPRINKVKIILPK

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=388, Percent_Identity=24.4845360824742, Blast_Score=128, Evalue=1e-29,
Organism=Escherichia coli, GI1790664, Length=426, Percent_Identity=21.830985915493, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI145693175, Length=414, Percent_Identity=25.1207729468599, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786879, Length=252, Percent_Identity=26.1904761904762, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87082033, Length=380, Percent_Identity=25, Blast_Score=86, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 46659; Mature: 46528

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLLLCILLVIPAFFNAGQFAILRLRSTKVQRLVEDGLPGSNSIIRLQKRLRRTLLIAE
CHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LGITISLISIGWICKNFASQWWGNNASINYLLDLGLFITVVLLATLISGLLPKALVLNQP
HCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCC
ETSALKLSPLIEAAIKWMSPFLSLLEGLALLILRLVGLNTQSESLTTAAFSAGELEKLIE
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCHHHHHHHHH
TGGVTGLKPDERNILEGVFALRDTQVREVMVPRSGMVTLPREVSFTQMMEEVHKTRHARY
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHCCEE
LVIDDSLDNVLGVLDLRQLADPIAKGAMQANSSLEPYIKPVVRVLETSTLAELLPLIKNG
EEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
NPLLLVVDEYGGTEGLITSADLTGEIVGDEIQFDNKESELRSLDDLKKIWLTSGEIEVIE
CEEEEEEECCCCCCCEEEECCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEE
LNRELNLKLPEADDHYTLAGFVLEKLQEIPSSGETFIHNEIVFEIISMKGPRINKVKIIL
ECCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEE
PK
CC
>Mature Secondary Structure 
SLLLLCILLVIPAFFNAGQFAILRLRSTKVQRLVEDGLPGSNSIIRLQKRLRRTLLIAE
HHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LGITISLISIGWICKNFASQWWGNNASINYLLDLGLFITVVLLATLISGLLPKALVLNQP
HCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCC
ETSALKLSPLIEAAIKWMSPFLSLLEGLALLILRLVGLNTQSESLTTAAFSAGELEKLIE
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCHHHHHHHHH
TGGVTGLKPDERNILEGVFALRDTQVREVMVPRSGMVTLPREVSFTQMMEEVHKTRHARY
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHCCEE
LVIDDSLDNVLGVLDLRQLADPIAKGAMQANSSLEPYIKPVVRVLETSTLAELLPLIKNG
EEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
NPLLLVVDEYGGTEGLITSADLTGEIVGDEIQFDNKESELRSLDDLKKIWLTSGEIEVIE
CEEEEEEECCCCCCCEEEECCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEE
LNRELNLKLPEADDHYTLAGFVLEKLQEIPSSGETFIHNEIVFEIISMKGPRINKVKIIL
ECCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEE
PK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]