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The map label for this gene is qri7

Identifier: 124022380

GI number: 124022380

Start: 630674

End: 631744

Strand: Direct

Name: qri7

Synonym: P9303_06711

Alternate gene names: 124022380

Gene position: 630674-631744 (Clockwise)

Preceding gene: 124022377

Following gene: 124022381

Centisome position: 23.51

GC content: 56.77

Gene sequence:

>1071_bases
ATGCCGACGGTGCTTGCCCTCGAAACAAGTTGTGACGAGTCGGCTGCCGCAGTCCTACGTCTAAATAACGGGTGTTTGCA
GGTTATCGCTAGCCGAATTGCTTCTCAGGTTGAGAAACATGCCCAGTGGGGAGGCGTGGTACCGGAAGTGGCCTCTCGCT
TGCATGTGGAGGCTCTGCCTCATCTTGTGGAGGAGGTTTTGCAGGAGGCGGGACAGTCGATGGCTCGCTTTGATGCTGTA
GCTGCAACGGTGACCCCTGGGCTGGCCGGAGCACTGATGGTGGGATCGGTGACAGGCCGATGTTTGGCTGCTCTCCATGC
GCTGCCTTTTTTTGGCATTCATCACCTGGAGGGGCATTTGGCTTCAGTGCTTTTGGCGGAACACCCTCCACGCCCTCCTT
ATCTGGTGCTACTTGTGAGCGGGGGACACACTGAGTTGATTCGGGTCGGGGCAGAGAGTGAGATGGTGCGTCTTGGACGT
AGCCATGATGATGCTGCTGGAGAGGCCTTTGACAAAGTTGGCCGTTTGCTCGGTTTGGCCTATCCAGGTGGCCCCGCTAT
TCAGGCGCTGGCCGCGGCCGGAGACTCTGGCAGATTTTCTTTGCCCAAAGGACGGGTCTCTAAGCCTGGTGGTGGCTTTC
ATCCCTACGATTTCTCTTTCAGCGGATTGAAGACCGCCATGCTGCGCCTGGTTCAGGCTCTTTCAGAGGCTGGTGAAGAC
CTGCCCCGCGCAGATCTTGCTGCCAGTTTTGAGCAAGTGGTTGCAGATGTTTTGGTCGAGCGCAGCTTGCTCTGCGCTAA
TGACCAGGGCCTAAAAACTGTGGTGATGGTTGGAGGAGTCGCGGCTAACCGCCGCCTAAGAGAACTGATGAGCAAACGTG
GACAAGAACAGGGGATTGAAGTGCACACGGCACCGCTTCGATACTGCACGGATAATGCCGCCATGATTGGAGCAGCGGCC
TTGCAGCGCTTGGTGTCTGGGGATGATGCCAGCTCTCTTGAGTTGGGAGTGGCAGCCCGATGGCCATTAGACAAAACCGA
GGATTTGTACCATTCACCTCCCCCATTTTGA

Upstream 100 bases:

>100_bases
ACAACGGCGAAGAGACGACGCATCGGTTTCGATTCCTGTAAGACCTGCTCCGGAACGGCAGGATGTCACAAGTAAAATGT
AAATGAGGCTTCCCACAACC

Downstream 100 bases:

>100_bases
AGAAGCGAATTAGCTTGACCTTGTCTGCTGTGCAGCGATGGCTTCTGAATCTCCACTTGATTCCAACACCTCTGCGGAAC
CTGTCAGTAGTGAAGAGCTA

Product: DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MPTVLALETSCDESAAAVLRLNNGCLQVIASRIASQVEKHAQWGGVVPEVASRLHVEALPHLVEEVLQEAGQSMARFDAV
AATVTPGLAGALMVGSVTGRCLAALHALPFFGIHHLEGHLASVLLAEHPPRPPYLVLLVSGGHTELIRVGAESEMVRLGR
SHDDAAGEAFDKVGRLLGLAYPGGPAIQALAAAGDSGRFSLPKGRVSKPGGGFHPYDFSFSGLKTAMLRLVQALSEAGED
LPRADLAASFEQVVADVLVERSLLCANDQGLKTVVMVGGVAANRRLRELMSKRGQEQGIEVHTAPLRYCTDNAAMIGAAA
LQRLVSGDDASSLELGVAARWPLDKTEDLYHSPPPF

Sequences:

>Translated_356_residues
MPTVLALETSCDESAAAVLRLNNGCLQVIASRIASQVEKHAQWGGVVPEVASRLHVEALPHLVEEVLQEAGQSMARFDAV
AATVTPGLAGALMVGSVTGRCLAALHALPFFGIHHLEGHLASVLLAEHPPRPPYLVLLVSGGHTELIRVGAESEMVRLGR
SHDDAAGEAFDKVGRLLGLAYPGGPAIQALAAAGDSGRFSLPKGRVSKPGGGFHPYDFSFSGLKTAMLRLVQALSEAGED
LPRADLAASFEQVVADVLVERSLLCANDQGLKTVVMVGGVAANRRLRELMSKRGQEQGIEVHTAPLRYCTDNAAMIGAAA
LQRLVSGDDASSLELGVAARWPLDKTEDLYHSPPPF
>Mature_355_residues
PTVLALETSCDESAAAVLRLNNGCLQVIASRIASQVEKHAQWGGVVPEVASRLHVEALPHLVEEVLQEAGQSMARFDAVA
ATVTPGLAGALMVGSVTGRCLAALHALPFFGIHHLEGHLASVLLAEHPPRPPYLVLLVSGGHTELIRVGAESEMVRLGRS
HDDAAGEAFDKVGRLLGLAYPGGPAIQALAAAGDSGRFSLPKGRVSKPGGGFHPYDFSFSGLKTAMLRLVQALSEAGEDL
PRADLAASFEQVVADVLVERSLLCANDQGLKTVVMVGGVAANRRLRELMSKRGQEQGIEVHTAPLRYCTDNAAMIGAAAL
QRLVSGDDASSLELGVAARWPLDKTEDLYHSPPPF

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=351, Percent_Identity=34.4729344729345, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI8923380, Length=349, Percent_Identity=29.512893982808, Blast_Score=118, Evalue=7e-27,
Organism=Escherichia coli, GI1789445, Length=340, Percent_Identity=45, Blast_Score=271, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI17557464, Length=343, Percent_Identity=34.1107871720117, Blast_Score=148, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI71995670, Length=307, Percent_Identity=28.6644951140065, Blast_Score=97, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6320099, Length=369, Percent_Identity=27.3712737127371, Blast_Score=106, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6322891, Length=294, Percent_Identity=26.8707482993197, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI20129063, Length=359, Percent_Identity=30.3621169916435, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI21357207, Length=319, Percent_Identity=29.7805642633229, Blast_Score=122, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_PROM3 (A2C7G2)

Other databases:

- EMBL:   CP000554
- RefSeq:   YP_001016687.1
- ProteinModelPortal:   A2C7G2
- SMR:   A2C7G2
- STRING:   A2C7G2
- MEROPS:   M22.001
- GeneID:   4776277
- GenomeReviews:   CP000554_GR
- KEGG:   pmf:P9303_06711
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PLYGVNH
- ProtClustDB:   PRK09604
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 37484; Mature: 37353

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTVLALETSCDESAAAVLRLNNGCLQVIASRIASQVEKHAQWGGVVPEVASRLHVEALP
CCCEEEEECCCCCHHHHHHEECCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
HLVEEVLQEAGQSMARFDAVAATVTPGLAGALMVGSVTGRCLAALHALPFFGIHHLEGHL
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASVLLAEHPPRPPYLVLLVSGGHTELIRVGAESEMVRLGRSHDDAAGEAFDKVGRLLGLA
HHHHHHCCCCCCCEEEEEEECCCEEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
YPGGPAIQALAAAGDSGRFSLPKGRVSKPGGGFHPYDFSFSGLKTAMLRLVQALSEAGED
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
LPRADLAASFEQVVADVLVERSLLCANDQGLKTVVMVGGVAANRRLRELMSKRGQEQGIE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHCCHHCCCE
VHTAPLRYCTDNAAMIGAAALQRLVSGDDASSLELGVAARWPLDKTEDLYHSPPPF
EEECCHHHHCCCHHHHHHHHHHHHHCCCCCCCEEECEEEECCCCCCHHHCCCCCCC
>Mature Secondary Structure 
PTVLALETSCDESAAAVLRLNNGCLQVIASRIASQVEKHAQWGGVVPEVASRLHVEALP
CCEEEEECCCCCHHHHHHEECCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
HLVEEVLQEAGQSMARFDAVAATVTPGLAGALMVGSVTGRCLAALHALPFFGIHHLEGHL
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASVLLAEHPPRPPYLVLLVSGGHTELIRVGAESEMVRLGRSHDDAAGEAFDKVGRLLGLA
HHHHHHCCCCCCCEEEEEEECCCEEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
YPGGPAIQALAAAGDSGRFSLPKGRVSKPGGGFHPYDFSFSGLKTAMLRLVQALSEAGED
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
LPRADLAASFEQVVADVLVERSLLCANDQGLKTVVMVGGVAANRRLRELMSKRGQEQGIE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHCCHHCCCE
VHTAPLRYCTDNAAMIGAAALQRLVSGDDASSLELGVAARWPLDKTEDLYHSPPPF
EEECCHHHHCCCHHHHHHHHHHHHHCCCCCCCEEECEEEECCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA