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The map label for this gene is fabZ

Identifier: 124022261

GI number: 124022261

Start: 534823

End: 535230

Strand: Direct

Name: fabZ

Synonym: P9303_05511

Alternate gene names: 124022261

Gene position: 534823-535230 (Clockwise)

Preceding gene: 124022260

Following gene: 124022262

Centisome position: 19.94

GC content: 55.88

Gene sequence:

>408_bases
ATGGGGCTGCTGCCTCATCGTTATCCGTTTGCTCTGGTTGATCGTGTTGTGCTCCATGAACCTGGCCAGCGGGCTGTTGC
GATCAAAAATGTGACCCTCAATGAACCTCAGTTCCAGGGTCATTTCCCTGGTCGTCCTTTGATGCCTGGGGTCTTGATTG
TTGAGGCGATGGCCCAGGTGGGTGGTTTGATCGTGGCCCAGATGCCAGATCTGCCCAAGGGGTTATTCGTGTTTGCAGGT
ATCGATGCAGTTCGTTTCCGCCGTCCGGTGGTGCCAGGAGATCAGCTCACGATTAGCTGCGAGCTGCTTAGCTTGAAGCG
GCAGCGCTTTGGCAAAGTCAGGGGGGAAGCCAGGGTGGAGGGCCAGCTGGTTTGCTCTGGTGAGTTGATGTTTTCCTTGG
TGGACTGA

Upstream 100 bases:

>100_bases
TCCACAACGATCTGGCGAATGCTCTCCTTGCCGTCTGTCCTGTGACTGTCTCTTGACCGATCCCTCTCCTAATACTGCAG
TGTTGACAAGTGAGCAGATC

Downstream 100 bases:

>100_bases
GGATCATGAGCGAGGTGGGCAAACTCTCAGCGATCACTGCCGAAAAAAAGGCTCAGGTTCACCCTGCGGCTGTGGTGGAT
CCTCGTGCTGAGCTCGCTTC

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 135; Mature: 134

Protein sequence:

>135_residues
MGLLPHRYPFALVDRVVLHEPGQRAVAIKNVTLNEPQFQGHFPGRPLMPGVLIVEAMAQVGGLIVAQMPDLPKGLFVFAG
IDAVRFRRPVVPGDQLTISCELLSLKRQRFGKVRGEARVEGQLVCSGELMFSLVD

Sequences:

>Translated_135_residues
MGLLPHRYPFALVDRVVLHEPGQRAVAIKNVTLNEPQFQGHFPGRPLMPGVLIVEAMAQVGGLIVAQMPDLPKGLFVFAG
IDAVRFRRPVVPGDQLTISCELLSLKRQRFGKVRGEARVEGQLVCSGELMFSLVD
>Mature_134_residues
GLLPHRYPFALVDRVVLHEPGQRAVAIKNVTLNEPQFQGHFPGRPLMPGVLIVEAMAQVGGLIVAQMPDLPKGLFVFAGI
DAVRFRRPVVPGDQLTISCELLSLKRQRFGKVRGEARVEGQLVCSGELMFSLVD

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=130, Percent_Identity=50, Blast_Score=127, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_PROMM (Q7V5X4)

Other databases:

- EMBL:   BX548175
- RefSeq:   NP_895238.1
- ProteinModelPortal:   Q7V5X4
- SMR:   Q7V5X4
- STRING:   Q7V5X4
- GeneID:   1727912
- GenomeReviews:   BX548175_GR
- KEGG:   pmt:PMT1411
- NMPDR:   fig|74547.1.peg.1405
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- ProtClustDB:   PRK00006
- BioCyc:   PMAR74547:PMT1411-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 14828; Mature: 14697

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: ACT_SITE 48-48

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLLPHRYPFALVDRVVLHEPGQRAVAIKNVTLNEPQFQGHFPGRPLMPGVLIVEAMAQV
CCCCCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
GGLIVAQMPDLPKGLFVFAGIDAVRFRRPVVPGDQLTISCELLSLKRQRFGKVRGEARVE
CCEEEEECCCCCCCEEEEECCCHHHHCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCEEEC
GQLVCSGELMFSLVD
EEEEECCCEEEEECC
>Mature Secondary Structure 
GLLPHRYPFALVDRVVLHEPGQRAVAIKNVTLNEPQFQGHFPGRPLMPGVLIVEAMAQV
CCCCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
GGLIVAQMPDLPKGLFVFAGIDAVRFRRPVVPGDQLTISCELLSLKRQRFGKVRGEARVE
CCEEEEECCCCCCCEEEEECCCHHHHCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCEEEC
GQLVCSGELMFSLVD
EEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642