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The map label for this gene is engD [H]

Identifier: 123968846

GI number: 123968846

Start: 1089060

End: 1090151

Strand: Reverse

Name: engD [H]

Synonym: A9601_13131

Alternate gene names: 123968846

Gene position: 1090151-1089060 (Counterclockwise)

Preceding gene: 123968852

Following gene: 123968843

Centisome position: 65.28

GC content: 33.06

Gene sequence:

>1092_bases
ATGTTAAAAGCAGGTATTATTGGATTACCAAATGTTGGAAAATCAACTCTATTTAATGCACTTGTAGAAAATGCTAAGGC
CCAAGCGGCTAATTTTCCCTTCTGTACTATAGAACCTAATAAAGGCATAGTTTCAGTACCAGATCAAAGGCTGCAAGAGT
TAGGTAATTTAAGTTCTAGCCAAAATATTATCCCAACAAAAATTGAATTTGTAGATATCGCAGGACTAGTAAAAGGAGCC
AGCAAAGGTGAGGGTTTGGGAAATAAATTTTTATCAAATATTAGGGAGGTTGATGCAATAGTTCATGTTGTGAGGTGCTT
TGAAGATAGTGATGTAATTCATGTTTCAGGGAAGGTGGATCCCCTGGATGACATTGAGATAATAAACCTGGAATTGAATT
TAGCTGATTTATCCCAACTCCAAAAAAGGAGAGAAAGAATAAAAAAACAGGTTAGAACTAGTAAAGAGGCAGCTAAAGAA
GATACCTTACTAGAAAAAATTGAAGAAGAGCTAGAAAAAGGCCTTTCAGTTAGATCAATATCTTTGAATGAAGAAGAAAA
TTTAATAATTAAGCAACTAGGCTTCCTTACTGCAAAACCAATTATTTACGCAACAAATTTGAATGAAAATGATTTAGCTT
TAGGTAATGATTTCTCATCAAAAGTTCAGAGTTTTGCAAGGAATGAAAATACAGAATGTATAAAAATATCAGCGCAAGTC
GAATCTGAATTAATAGAGTTAGAACAAGAAGATAAAAAAGACTATCTTATTGGTTTAGGAGTAGAAGAAGGGGGATTAAG
TTCTTTAATTAGATCAACATATAAATTATTGGGATTAAAAACTTATTTCACTACCGGAGAAAAGGAGACAAAAGCTTGGA
CAATAAAAGATGGGATGACTGCGCCACAGGCAGCAGGAGTAATTCATACTGATTTTGAAAAAGGATTTATAAGAGCTCAG
ACTATTTCGTATCAAAATTTAATTGATTCAGGTTCAATTGCCAATGCAAAAACTAAAGGCCTTTTAAGAAGTGAAGGTAA
GGAATATATTGTTAACGAAGGTGATGTAATGGAGTTCTTATTTAACGTTTAG

Upstream 100 bases:

>100_bases
ATAATCAAGACGATTATAATTAACTTATCCAAGATTGGTTAAGTAAATACTATATTACTAGAAGATGTTTTCTTGATAAT
TTTTCCATAAGTTTTTTCAA

Downstream 100 bases:

>100_bases
TAAGTCTCTTAAGGCTTACTATTTTGCTTTTTGAATTTAAATTCAAAAAATGAAATTAATAAAATTAAGATACATCCTAA
GCAACTTCCTATTAACCCAA

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MLKAGIIGLPNVGKSTLFNALVENAKAQAANFPFCTIEPNKGIVSVPDQRLQELGNLSSSQNIIPTKIEFVDIAGLVKGA
SKGEGLGNKFLSNIREVDAIVHVVRCFEDSDVIHVSGKVDPLDDIEIINLELNLADLSQLQKRRERIKKQVRTSKEAAKE
DTLLEKIEEELEKGLSVRSISLNEEENLIIKQLGFLTAKPIIYATNLNENDLALGNDFSSKVQSFARNENTECIKISAQV
ESELIELEQEDKKDYLIGLGVEEGGLSSLIRSTYKLLGLKTYFTTGEKETKAWTIKDGMTAPQAAGVIHTDFEKGFIRAQ
TISYQNLIDSGSIANAKTKGLLRSEGKEYIVNEGDVMEFLFNV

Sequences:

>Translated_363_residues
MLKAGIIGLPNVGKSTLFNALVENAKAQAANFPFCTIEPNKGIVSVPDQRLQELGNLSSSQNIIPTKIEFVDIAGLVKGA
SKGEGLGNKFLSNIREVDAIVHVVRCFEDSDVIHVSGKVDPLDDIEIINLELNLADLSQLQKRRERIKKQVRTSKEAAKE
DTLLEKIEEELEKGLSVRSISLNEEENLIIKQLGFLTAKPIIYATNLNENDLALGNDFSSKVQSFARNENTECIKISAQV
ESELIELEQEDKKDYLIGLGVEEGGLSSLIRSTYKLLGLKTYFTTGEKETKAWTIKDGMTAPQAAGVIHTDFEKGFIRAQ
TISYQNLIDSGSIANAKTKGLLRSEGKEYIVNEGDVMEFLFNV
>Mature_363_residues
MLKAGIIGLPNVGKSTLFNALVENAKAQAANFPFCTIEPNKGIVSVPDQRLQELGNLSSSQNIIPTKIEFVDIAGLVKGA
SKGEGLGNKFLSNIREVDAIVHVVRCFEDSDVIHVSGKVDPLDDIEIINLELNLADLSQLQKRRERIKKQVRTSKEAAKE
DTLLEKIEEELEKGLSVRSISLNEEENLIIKQLGFLTAKPIIYATNLNENDLALGNDFSSKVQSFARNENTECIKISAQV
ESELIELEQEDKKDYLIGLGVEEGGLSSLIRSTYKLLGLKTYFTTGEKETKAWTIKDGMTAPQAAGVIHTDFEKGFIRAQ
TISYQNLIDSGSIANAKTKGLLRSEGKEYIVNEGDVMEFLFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=368, Percent_Identity=41.0326086956522, Blast_Score=272, Evalue=4e-73,
Organism=Homo sapiens, GI58761502, Length=184, Percent_Identity=36.9565217391304, Blast_Score=126, Evalue=3e-29,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=54.5454545454545, Blast_Score=397, Evalue=1e-112,
Organism=Escherichia coli, GI1789574, Length=128, Percent_Identity=31.25, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17509631, Length=367, Percent_Identity=43.5967302452316, Blast_Score=287, Evalue=6e-78,
Organism=Saccharomyces cerevisiae, GI6319499, Length=368, Percent_Identity=39.945652173913, Blast_Score=244, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6321773, Length=378, Percent_Identity=35.1851851851852, Blast_Score=216, Evalue=7e-57,
Organism=Saccharomyces cerevisiae, GI6321649, Length=174, Percent_Identity=39.0804597701149, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24640873, Length=376, Percent_Identity=40.4255319148936, Blast_Score=275, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24640877, Length=376, Percent_Identity=40.4255319148936, Blast_Score=275, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24640875, Length=376, Percent_Identity=40.4255319148936, Blast_Score=275, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24640879, Length=334, Percent_Identity=37.7245508982036, Blast_Score=221, Evalue=5e-58,
Organism=Drosophila melanogaster, GI24585318, Length=141, Percent_Identity=35.4609929078014, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40022; Mature: 40022

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKAGIIGLPNVGKSTLFNALVENAKAQAANFPFCTIEPNKGIVSVPDQRLQELGNLSSS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEECCHHHHHHHHCCCCC
QNIIPTKIEFVDIAGLVKGASKGEGLGNKFLSNIREVDAIVHVVRCFEDSDVIHVSGKVD
CCCCCCEEEEEEHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
PLDDIEIINLELNLADLSQLQKRRERIKKQVRTSKEAAKEDTLLEKIEEELEKGLSVRSI
CCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
SLNEEENLIIKQLGFLTAKPIIYATNLNENDLALGNDFSSKVQSFARNENTECIKISAQV
ECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEHHH
ESELIELEQEDKKDYLIGLGVEEGGLSSLIRSTYKLLGLKTYFTTGEKETKAWTIKDGMT
HHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCEEEECCCCC
APQAAGVIHTDFEKGFIRAQTISYQNLIDSGSIANAKTKGLLRSEGKEYIVNEGDVMEFL
CCCCCCCEEECCCCCEEEEEEECHHHHHCCCCCCCHHHHHHHHHCCCEEECCCCHHHHHH
FNV
HCC
>Mature Secondary Structure
MLKAGIIGLPNVGKSTLFNALVENAKAQAANFPFCTIEPNKGIVSVPDQRLQELGNLSSS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEECCHHHHHHHHCCCCC
QNIIPTKIEFVDIAGLVKGASKGEGLGNKFLSNIREVDAIVHVVRCFEDSDVIHVSGKVD
CCCCCCEEEEEEHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
PLDDIEIINLELNLADLSQLQKRRERIKKQVRTSKEAAKEDTLLEKIEEELEKGLSVRSI
CCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
SLNEEENLIIKQLGFLTAKPIIYATNLNENDLALGNDFSSKVQSFARNENTECIKISAQV
ECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEHHH
ESELIELEQEDKKDYLIGLGVEEGGLSSLIRSTYKLLGLKTYFTTGEKETKAWTIKDGMT
HHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCEEEECCCCC
APQAAGVIHTDFEKGFIRAQTISYQNLIDSGSIANAKTKGLLRSEGKEYIVNEGDVMEFL
CCCCCCCEEECCCCCEEEEEEECHHHHHCCCCCCCHHHHHHHHHCCCEEECCCCHHHHHH
FNV
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]