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The map label for this gene is crtH [H]

Identifier: 123968754

GI number: 123968754

Start: 1038185

End: 1039729

Strand: Reverse

Name: crtH [H]

Synonym: A9601_12211

Alternate gene names: 123968754

Gene position: 1039729-1038185 (Counterclockwise)

Preceding gene: 123968755

Following gene: 123968753

Centisome position: 62.26

GC content: 33.98

Gene sequence:

>1545_bases
ATGGAATTAAATAAGGAAAACTTCGATGCAATTATTATTGGCTCAGGAATTGGAGGATTAGTAACTGCTTCACAATTGGC
GGCTAAGGGAGCTCAAGTATTAGTTCTTGAAAAATATATTATTCCAGGCGGGAGTGGAGGCTCATTTAAGAGAAAAGGCT
ATACCTTTGACGTCGGGGCTTCAATGATTTTTGGATTTGGAGAGAAAGGTTATACCAATTTATTAACTCGTGCTTTGAAA
GATGTGAATGAAAAATGCGAAACTATTCCCGATCCTGTTCAACTGGAATATCACTTGCCAAATAACTTAAATATTTCTGT
AGATAAAAATTATGAGCAATTTATAAGCAAATTATCAGCTATTTTTCCCAAGGAAAAAAAAGGTATCAAGAAATTCTATG
ATACTTGTGCAAGTGTATTTAAATGTTTAGATTCAATGCCTCTTTTATCAATAGAGGATCCAAATTATCTTTTTAAAGTT
TTCTTTAAATCTCCATTATCCTGTTTAGGGTTAGCTAGATGGCTACCTGCAAATGCAGGAGATGTTGCGAGAAAGTTTAT
AAAAGATCCAGAACTTTTAAAATTTATTGATATCGAATGTTTTTGTTGGTCTGTAATGCCAGCTCTAAAAACCCCTATGA
TTAATGCGGGAATGGTATTTACAGATAGGCATGCGGGGGGGATAAATTATCCAAAAGGGGGAGTTGGAACGATAGCAGAG
AAGTTTGTTTCTGGGATTGAAAAATTAGGAGGAAAAGTTAGATATAAAGCCAATGTGACTGAAATCCTCTTAAAGGATGA
TAAAGCGGTAGGAGTTAAGCTCTCAAATGGGGAAGAAATATATTCAGATATTATTGTATCCAACTCCACTAGATGGGATA
CATTTGGATTAAAAGATAATACTAAAGGATTAATTTCTAGTAAAAACGTGCCAAAAAGTGAATATAAGTGGTCAGAAACT
TATAAACCCTCACCTTCTTTTGTTTCGATTCACCTTGGAGTAGAAAAAAATCTAATACCAGATAATTTTAATTGTCATCA
TATAATCGTTGAAAATTGGGATGAATTAGAAAGCGAAAAGGGAGTTATTTTTGTTTCTATACCTACTTTGCTTGACTCGT
CTTTGGCTCCAGAAGGTAAACATATTTTACATGCATTTACTCCTTCATTGATGAGTGAATGGGAAGGCCTATCAAGGAAA
GAATATATGCAAAAGAAAGAAAAATATTTTTCTTTTCTTGTTGAAAAAATATCAACTATTCTTCCTAATCTTGAACAAAA
TATTGATCACAAAGAAATTGGTACTCCCAAAACTCATAAAAAGTTTCTTGGAAGATATGAAGGTAGTTATGGGCCAATTC
CCAGTAAAAAGTTGCTTGGACTTTTGCCAATGCCTTTCAACACTACAAAAATTCAAAACCTATATTGTGTAGGGGATTCT
TGCTTCCCTGGCCAAGGCCTAAATGCAGTTGCTTTTAGTGGATACGCATGCGCTCACAAAATAGGTGCAAAGTTAAACAT
AAACAGTTTTAAATTGCCCGATTAA

Upstream 100 bases:

>100_bases
AGAAGCCTTGAATGACTTTAAAAATCAACTAGATTCTTGTTTTGATAAAGACCACTTACTTAGCAAAATTTACTAAGATT
AATTATCAAAGATCCAAAAA

Downstream 100 bases:

>100_bases
AAGGATTCCTTCTGAAATGATAGAAAAATTTAAAACTCTTATTTTTGTGAAAAGTTCGTTAATTTCTCTTTATTTAGCGC
TTACAATTCCTTTACCATTT

Product: putative carotenoid isomerase

Products: NA

Alternate protein names: Phytoene desaturase [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MELNKENFDAIIIGSGIGGLVTASQLAAKGAQVLVLEKYIIPGGSGGSFKRKGYTFDVGASMIFGFGEKGYTNLLTRALK
DVNEKCETIPDPVQLEYHLPNNLNISVDKNYEQFISKLSAIFPKEKKGIKKFYDTCASVFKCLDSMPLLSIEDPNYLFKV
FFKSPLSCLGLARWLPANAGDVARKFIKDPELLKFIDIECFCWSVMPALKTPMINAGMVFTDRHAGGINYPKGGVGTIAE
KFVSGIEKLGGKVRYKANVTEILLKDDKAVGVKLSNGEEIYSDIIVSNSTRWDTFGLKDNTKGLISSKNVPKSEYKWSET
YKPSPSFVSIHLGVEKNLIPDNFNCHHIIVENWDELESEKGVIFVSIPTLLDSSLAPEGKHILHAFTPSLMSEWEGLSRK
EYMQKKEKYFSFLVEKISTILPNLEQNIDHKEIGTPKTHKKFLGRYEGSYGPIPSKKLLGLLPMPFNTTKIQNLYCVGDS
CFPGQGLNAVAFSGYACAHKIGAKLNINSFKLPD

Sequences:

>Translated_514_residues
MELNKENFDAIIIGSGIGGLVTASQLAAKGAQVLVLEKYIIPGGSGGSFKRKGYTFDVGASMIFGFGEKGYTNLLTRALK
DVNEKCETIPDPVQLEYHLPNNLNISVDKNYEQFISKLSAIFPKEKKGIKKFYDTCASVFKCLDSMPLLSIEDPNYLFKV
FFKSPLSCLGLARWLPANAGDVARKFIKDPELLKFIDIECFCWSVMPALKTPMINAGMVFTDRHAGGINYPKGGVGTIAE
KFVSGIEKLGGKVRYKANVTEILLKDDKAVGVKLSNGEEIYSDIIVSNSTRWDTFGLKDNTKGLISSKNVPKSEYKWSET
YKPSPSFVSIHLGVEKNLIPDNFNCHHIIVENWDELESEKGVIFVSIPTLLDSSLAPEGKHILHAFTPSLMSEWEGLSRK
EYMQKKEKYFSFLVEKISTILPNLEQNIDHKEIGTPKTHKKFLGRYEGSYGPIPSKKLLGLLPMPFNTTKIQNLYCVGDS
CFPGQGLNAVAFSGYACAHKIGAKLNINSFKLPD
>Mature_514_residues
MELNKENFDAIIIGSGIGGLVTASQLAAKGAQVLVLEKYIIPGGSGGSFKRKGYTFDVGASMIFGFGEKGYTNLLTRALK
DVNEKCETIPDPVQLEYHLPNNLNISVDKNYEQFISKLSAIFPKEKKGIKKFYDTCASVFKCLDSMPLLSIEDPNYLFKV
FFKSPLSCLGLARWLPANAGDVARKFIKDPELLKFIDIECFCWSVMPALKTPMINAGMVFTDRHAGGINYPKGGVGTIAE
KFVSGIEKLGGKVRYKANVTEILLKDDKAVGVKLSNGEEIYSDIIVSNSTRWDTFGLKDNTKGLISSKNVPKSEYKWSET
YKPSPSFVSIHLGVEKNLIPDNFNCHHIIVENWDELESEKGVIFVSIPTLLDSSLAPEGKHILHAFTPSLMSEWEGLSRK
EYMQKKEKYFSFLVEKISTILPNLEQNIDHKEIGTPKTHKKFLGRYEGSYGPIPSKKLLGLLPMPFNTTKIQNLYCVGDS
CFPGQGLNAVAFSGYACAHKIGAKLNINSFKLPD

Specific function: This enzyme converts phytoene into lycopene via the intermediaries of phytofluene, zeta-carotene and neurosporene by the introduction of four double bonds [H]

COG id: COG1233

COG function: function code Q; Phytoene dehydrogenase and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid/retinoid oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI203098013, Length=525, Percent_Identity=23.4285714285714, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17540238, Length=546, Percent_Identity=22.1611721611722, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR008150
- InterPro:   IPR014105 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: NA

Molecular weight: Translated: 57024; Mature: 57024

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELNKENFDAIIIGSGIGGLVTASQLAAKGAQVLVLEKYIIPGGSGGSFKRKGYTFDVGA
CCCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCEEEECCC
SMIFGFGEKGYTNLLTRALKDVNEKCETIPDPVQLEYHLPNNLNISVDKNYEQFISKLSA
HHEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCHHHHHHHHHH
IFPKEKKGIKKFYDTCASVFKCLDSMPLLSIEDPNYLFKVFFKSPLSCLGLARWLPANAG
HCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCHH
DVARKFIKDPELLKFIDIECFCWSVMPALKTPMINAGMVFTDRHAGGINYPKGGVGTIAE
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHHHHH
KFVSGIEKLGGKVRYKANVTEILLKDDKAVGVKLSNGEEIYSDIIVSNSTRWDTFGLKDN
HHHHHHHHHCCEEEEECCCEEEEEECCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCC
TKGLISSKNVPKSEYKWSETYKPSPSFVSIHLGVEKNLIPDNFNCHHIIVENWDELESEK
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEECCHHHHCCCC
GVIFVSIPTLLDSSLAPEGKHILHAFTPSLMSEWEGLSRKEYMQKKEKYFSFLVEKISTI
CEEEEEEHHHHCCCCCCCCCHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LPNLEQNIDHKEIGTPKTHKKFLGRYEGSYGPIPSKKLLGLLPMPFNTTKIQNLYCVGDS
HCCHHHCCCHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHEECCCCCCCCEECEEEEECCC
CFPGQGLNAVAFSGYACAHKIGAKLNINSFKLPD
CCCCCCCCEEEECCHHHHHHCCCEECCCCCCCCC
>Mature Secondary Structure
MELNKENFDAIIIGSGIGGLVTASQLAAKGAQVLVLEKYIIPGGSGGSFKRKGYTFDVGA
CCCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCEEEECCC
SMIFGFGEKGYTNLLTRALKDVNEKCETIPDPVQLEYHLPNNLNISVDKNYEQFISKLSA
HHEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCHHHHHHHHHH
IFPKEKKGIKKFYDTCASVFKCLDSMPLLSIEDPNYLFKVFFKSPLSCLGLARWLPANAG
HCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCHH
DVARKFIKDPELLKFIDIECFCWSVMPALKTPMINAGMVFTDRHAGGINYPKGGVGTIAE
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHHHHH
KFVSGIEKLGGKVRYKANVTEILLKDDKAVGVKLSNGEEIYSDIIVSNSTRWDTFGLKDN
HHHHHHHHHCCEEEEECCCEEEEEECCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCC
TKGLISSKNVPKSEYKWSETYKPSPSFVSIHLGVEKNLIPDNFNCHHIIVENWDELESEK
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEECCHHHHCCCC
GVIFVSIPTLLDSSLAPEGKHILHAFTPSLMSEWEGLSRKEYMQKKEKYFSFLVEKISTI
CEEEEEEHHHHCCCCCCCCCHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LPNLEQNIDHKEIGTPKTHKKFLGRYEGSYGPIPSKKLLGLLPMPFNTTKIQNLYCVGDS
HCCHHHCCCHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHEECCCCCCCCEECEEEEECCC
CFPGQGLNAVAFSGYACAHKIGAKLNINSFKLPD
CCCCCCCCEEEECCHHHHHHCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2254247 [H]