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The map label for this gene is recD [H]

Identifier: 123968741

GI number: 123968741

Start: 1024556

End: 1026259

Strand: Reverse

Name: recD [H]

Synonym: A9601_12081

Alternate gene names: 123968741

Gene position: 1026259-1024556 (Counterclockwise)

Preceding gene: 123968742

Following gene: 123968740

Centisome position: 61.46

GC content: 24.0

Gene sequence:

>1704_bases
ATGACTAAAACCTCTACAGATATTGAAAAGTTCCAATACGATCATATATTTAATTTAATCTTAGGTATTTTCAAATTTAG
TGAAAAAAAATATGGAAATTTCGTAAAGGATGTAATAAGAATCTTATTAGATTTTGAAAAAAATGGTGAAACTATTATTG
ATGTTGATAATAGTTTAATAATCTTTGAATTATTAGAAGATGGCTGGCCCAATAAACATATACATGTTCTAAAAACTATA
GGTTTGATTGGTTCCCTTCATTCTCCATTCGTATTAGTAAATAGAAAATTATCCTTATCAAAATGGTCAAAAAAGATTGA
AAGAGTTATTAATTCATTCCTAAAAAAAATAGATACCGTTAATTTAATGAACTCAATAATTTTTAAAGATGATAATAAAA
TTGATGAAATTAAAAATATATTTAAATATTCAAACATAGTTTTCCTTCAAGGAGGACCAGGTACGGGTAAAACCACTTTA
ATAATTAAGTTAATATTAGAACTCCTTCAGATTGATAACTTTTTAAATATTGGTTTGTCTGCTCCAACTGGTAAAGCTAC
AGCACGTTTAAAAGAAGCTCTCAATGATAAAAAAAATATTTCCTTCAATAAATTTCTAGACCAAATAGAATTTCAAACTT
TACATAGATGGATTTTAAATTCTCAAAATAAATCTCTTAAGTTGAAATTTAAACTAAAAGAGCTTGATATTTTCATAATT
GATGAAATGTCAATGGTTAATATCGATTTGATTGAATCAGTTTTAGATTTGCTAGCAAAAGACTGTAAAATTATTTTAGT
TGGAGATAAAAATCAATTGTCTCCAGTAAATAACTGTTCTATATGGAATTATTTGTTTGAATATTCCGATAATAGTTCAA
TTAAATCTTGTGTAGTAAATTTAGAAAAAACTTATAGAAATATTGGAGATATAGCATTAATTAGTAGTTTAATATTTAAT
AATGATTTTTCTTTACTTAATCAAAAGATAAAAGAATTAGAAAAAGATAATAATTCAAAAGAAATTACTATTTCAAAGAG
TAGTGAAAAAGATATCCCAAAAGATCTATTATTTTCGATTACAAGTCATCTAAAGCAGTTAAATATTTCAACTTCAAATT
TAAGTAAAAAAAAATATATATTTGATGAGAGTATAGATAATTTATTGCTTAATGAAAAAGATTTAGTAGATAAGATATTT
CTGGATTTACAAAGTCACTTGATTTTATGCGAAAAAAATTCGGGAATATGGAGTGTTGAATATTTGAATGAAATTGTTTT
TGGTCAAAAAAAACCCTATGACCTTAAAACTCTTAAAGAGGGTATTCCCATCATGTGTACAAAAAATAATAATGAACTAG
GATTGTCAAATGGGGATATAGGAGTACTTATAGGTTTAAAAAATAAAAGAAAATATCTTTTTAGAAAATTTAATGATAAT
AACGAAGAAATTGTCTCATTAATTGATCCATCTAATTTAGAAAATGTTGTACCAGCAATAGCTTTTACTATTCATAAATC
TCAAGGAAGTGAATCTGAAAAAGTAAACATTTTGTGGTCCCAAAATTATAGAAGAAATAAATATGCTGTAAAAGAAAAAA
AAGATGATCAAAATATCTTTTGCAGAGATAATTTTGAAAGAAGGTTATTTTATACTGCTGTTACAAGAGCGAAAAAAACT
TTAAATATATTTTATTTAAATTAA

Upstream 100 bases:

>100_bases
GAATTATTTGAAAAATCTAAGTCTGAAGATATATCTCCAGGTATTTTTATTAGCAAGGCACCTTTAAAAAGAATTAATTA
TTTAGATAACCTTTTTTAGA

Downstream 100 bases:

>100_bases
ATTTTATTTTTGAGAAATTAGTAATATCTCAACCCCTAGATGTTAGATTAATAACTCGGCTCTGCAAGGCTAATCAACAA
TTTAAGTCAATTTAGATATT

Product: exodeoxyribonuclease V 67 kD polypeptide

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 567; Mature: 566

Protein sequence:

>567_residues
MTKTSTDIEKFQYDHIFNLILGIFKFSEKKYGNFVKDVIRILLDFEKNGETIIDVDNSLIIFELLEDGWPNKHIHVLKTI
GLIGSLHSPFVLVNRKLSLSKWSKKIERVINSFLKKIDTVNLMNSIIFKDDNKIDEIKNIFKYSNIVFLQGGPGTGKTTL
IIKLILELLQIDNFLNIGLSAPTGKATARLKEALNDKKNISFNKFLDQIEFQTLHRWILNSQNKSLKLKFKLKELDIFII
DEMSMVNIDLIESVLDLLAKDCKIILVGDKNQLSPVNNCSIWNYLFEYSDNSSIKSCVVNLEKTYRNIGDIALISSLIFN
NDFSLLNQKIKELEKDNNSKEITISKSSEKDIPKDLLFSITSHLKQLNISTSNLSKKKYIFDESIDNLLLNEKDLVDKIF
LDLQSHLILCEKNSGIWSVEYLNEIVFGQKKPYDLKTLKEGIPIMCTKNNNELGLSNGDIGVLIGLKNKRKYLFRKFNDN
NEEIVSLIDPSNLENVVPAIAFTIHKSQGSESEKVNILWSQNYRRNKYAVKEKKDDQNIFCRDNFERRLFYTAVTRAKKT
LNIFYLN

Sequences:

>Translated_567_residues
MTKTSTDIEKFQYDHIFNLILGIFKFSEKKYGNFVKDVIRILLDFEKNGETIIDVDNSLIIFELLEDGWPNKHIHVLKTI
GLIGSLHSPFVLVNRKLSLSKWSKKIERVINSFLKKIDTVNLMNSIIFKDDNKIDEIKNIFKYSNIVFLQGGPGTGKTTL
IIKLILELLQIDNFLNIGLSAPTGKATARLKEALNDKKNISFNKFLDQIEFQTLHRWILNSQNKSLKLKFKLKELDIFII
DEMSMVNIDLIESVLDLLAKDCKIILVGDKNQLSPVNNCSIWNYLFEYSDNSSIKSCVVNLEKTYRNIGDIALISSLIFN
NDFSLLNQKIKELEKDNNSKEITISKSSEKDIPKDLLFSITSHLKQLNISTSNLSKKKYIFDESIDNLLLNEKDLVDKIF
LDLQSHLILCEKNSGIWSVEYLNEIVFGQKKPYDLKTLKEGIPIMCTKNNNELGLSNGDIGVLIGLKNKRKYLFRKFNDN
NEEIVSLIDPSNLENVVPAIAFTIHKSQGSESEKVNILWSQNYRRNKYAVKEKKDDQNIFCRDNFERRLFYTAVTRAKKT
LNIFYLN
>Mature_566_residues
TKTSTDIEKFQYDHIFNLILGIFKFSEKKYGNFVKDVIRILLDFEKNGETIIDVDNSLIIFELLEDGWPNKHIHVLKTIG
LIGSLHSPFVLVNRKLSLSKWSKKIERVINSFLKKIDTVNLMNSIIFKDDNKIDEIKNIFKYSNIVFLQGGPGTGKTTLI
IKLILELLQIDNFLNIGLSAPTGKATARLKEALNDKKNISFNKFLDQIEFQTLHRWILNSQNKSLKLKFKLKELDIFIID
EMSMVNIDLIESVLDLLAKDCKIILVGDKNQLSPVNNCSIWNYLFEYSDNSSIKSCVVNLEKTYRNIGDIALISSLIFNN
DFSLLNQKIKELEKDNNSKEITISKSSEKDIPKDLLFSITSHLKQLNISTSNLSKKKYIFDESIDNLLLNEKDLVDKIFL
DLQSHLILCEKNSGIWSVEYLNEIVFGQKKPYDLKTLKEGIPIMCTKNNNELGLSNGDIGVLIGLKNKRKYLFRKFNDNN
EEIVSLIDPSNLENVVPAIAFTIHKSQGSESEKVNILWSQNYRRNKYAVKEKKDDQNIFCRDNFERRLFYTAVTRAKKTL
NIFYLN

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=456, Percent_Identity=26.0964912280702, Blast_Score=123, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 65442; Mature: 65310

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTSTDIEKFQYDHIFNLILGIFKFSEKKYGNFVKDVIRILLDFEKNGETIIDVDNSLI
CCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEE
IFELLEDGWPNKHIHVLKTIGLIGSLHSPFVLVNRKLSLSKWSKKIERVINSFLKKIDTV
EEEEHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
NLMNSIIFKDDNKIDEIKNIFKYSNIVFLQGGPGTGKTTLIIKLILELLQIDNFLNIGLS
HHHHHHHCCCCCCHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHCCHHCCCCC
APTGKATARLKEALNDKKNISFNKFLDQIEFQTLHRWILNSQNKSLKLKFKLKELDIFII
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEEEE
DEMSMVNIDLIESVLDLLAKDCKIILVGDKNQLSPVNNCSIWNYLFEYSDNSSIKSCVVN
CCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHH
LEKTYRNIGDIALISSLIFNNDFSLLNQKIKELEKDNNSKEITISKSSEKDIPKDLLFSI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHH
TSHLKQLNISTSNLSKKKYIFDESIDNLLLNEKDLVDKIFLDLQSHLILCEKNSGIWSVE
HHHHHHCCCCCCCCCCHHEEHHHHHHHHHCCCHHHHHHHHHHHHHCEEEEECCCCEEEHH
YLNEIVFGQKKPYDLKTLKEGIPIMCTKNNNELGLSNGDIGVLIGLKNKRKYLFRKFNDN
HHHHHHCCCCCCCCHHHHHCCCCEEEECCCCEECCCCCCEEEEEECCCCHHHHHHHCCCC
NEEIVSLIDPSNLENVVPAIAFTIHKSQGSESEKVNILWSQNYRRNKYAVKEKKDDQNIF
CCCEEEEECCCCHHHHHHHHEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEE
CRDNFERRLFYTAVTRAKKTLNIFYLN
ECCCCCHHHHHHHHHHCCCEEEEEEEC
>Mature Secondary Structure 
TKTSTDIEKFQYDHIFNLILGIFKFSEKKYGNFVKDVIRILLDFEKNGETIIDVDNSLI
CCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEE
IFELLEDGWPNKHIHVLKTIGLIGSLHSPFVLVNRKLSLSKWSKKIERVINSFLKKIDTV
EEEEHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
NLMNSIIFKDDNKIDEIKNIFKYSNIVFLQGGPGTGKTTLIIKLILELLQIDNFLNIGLS
HHHHHHHCCCCCCHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHCCHHCCCCC
APTGKATARLKEALNDKKNISFNKFLDQIEFQTLHRWILNSQNKSLKLKFKLKELDIFII
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEEEE
DEMSMVNIDLIESVLDLLAKDCKIILVGDKNQLSPVNNCSIWNYLFEYSDNSSIKSCVVN
CCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHH
LEKTYRNIGDIALISSLIFNNDFSLLNQKIKELEKDNNSKEITISKSSEKDIPKDLLFSI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHH
TSHLKQLNISTSNLSKKKYIFDESIDNLLLNEKDLVDKIFLDLQSHLILCEKNSGIWSVE
HHHHHHCCCCCCCCCCHHEEHHHHHHHHHCCCHHHHHHHHHHHHHCEEEEECCCCEEEHH
YLNEIVFGQKKPYDLKTLKEGIPIMCTKNNNELGLSNGDIGVLIGLKNKRKYLFRKFNDN
HHHHHHCCCCCCCCHHHHHCCCCEEEECCCCEECCCCCCEEEEEECCCCHHHHHHHCCCC
NEEIVSLIDPSNLENVVPAIAFTIHKSQGSESEKVNILWSQNYRRNKYAVKEKKDDQNIF
CCCEEEEECCCCHHHHHHHHEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEE
CRDNFERRLFYTAVTRAKKTLNIFYLN
ECCCCCHHHHHHHHHHCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]