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The map label for this gene is aroA [H]

Identifier: 123968204

GI number: 123968204

Start: 593638

End: 594948

Strand: Reverse

Name: aroA [H]

Synonym: A9601_06691

Alternate gene names: 123968204

Gene position: 594948-593638 (Counterclockwise)

Preceding gene: 123968211

Following gene: 123968203

Centisome position: 35.63

GC content: 37.45

Gene sequence:

>1311_bases
ATGAATAATATCCGCACAATAAAAGGTGGAGTTAATTTAAAAGGAAAAGTAAAAGTACCTGGAGATAAATCTATTTCTCA
TAGAGCTTTAATAATAGGAAGTATTGCTAATGGTGAGACGACTATTGAGGGGTTTTTACATTCTGAAGATCCACTTTCAA
CTGCTGATTGTCTTAGGAAATTAGGTGTAAACATACCAGAAATAAAGAAAAATGAGCCTTTTACGATTTCAGGTTTGGGT
CTTGATGGATTAAAAGAGCCCAAAGAAATTCTAAATTGTGGGAATTCGGGAACCACCATGAGATTATTAATGGGGTTACT
TGCCGGTCAAGAAGACAAGAATTTTATCTTAACAGGTGACATTTCTCTTAATGAAAGGCCAATGGGGAGAGTGGGCAAAC
CATTATCGTTGATGGGTGGCAAGATTTTTGGTAGAGAGAAAGGAAACAAAGCTCCAATCTCAATTGATGGGAATAAACTA
AAAGGTTGTGTTATTGGTACACCAGTAGCGAGTGCTCAAGTAAAATCTGCAATCTTATTGGCAGGACTCAAAGCTTCTGG
GACCACCTCTGTTATTGAACCAGCATCTTCAAGAGATCATACTGAAAGGATGTTAAAAGCTTTTGGAGCAGATATCAGCG
TCAGAGGAGAATTAGGAAGGAATGTAGTCATCAAATCAGGGGGGAAGTTAATTGGCCAGAGAATATTGATTCCCGGAGAC
ATAAGCTCTGCTTCTTTTTGGATGATTGCCGCATCTATTGTTCCAAATTCGGAGGTTTTAATTCAGAATGTCGGATTAAA
TCCTACTAGAACTGGAATTTTAAATGTAATGGATTCAATGGGGTGCAATTATGAGATTTTAGATAAATCGACCATTGCAG
GTGAACCTATTGGATCTATTAAAGTAAAGTCTTCAAATAATTTAAAATCATTCACTATTGAAGGTGATATCCTCCCAAAA
CTTATAGACGAAATTCCTATTCTTACTGTGGCTGCTTGTTTTTGTAATGGAGTTTCTGAAATTAAGGATGCCCAAGAATT
AAGAGTTAAGGAGACAGATCGATTAAAAGTCATGGCACGACAGTTACAAAAATTCGGTGCTGAAGTAACAGAGAAAGAGG
ATGGGTTAATTATTAATGGGCAATCAAAATTTAATTCTGCAGAAGTAGACAGTGAGACAGATCATCGAGTAGCAATGAGT
CTTGCTATTGCTTCACTTCTTGCTAAAGGTACCTCAAAAATCATGAGAGCAGATGCTGCTAGCGTCTCGTATCCCACTTT
TTGGGAAGACCTTGCCACACTAACTAACTAG

Upstream 100 bases:

>100_bases
ACAGTTACTTAATTTGATTATTTTTTTTTTAAAACAAACTTATTGATAATATATAAATAATTTGTTTCTACAGAAATCTT
ATCAAGTATTTAATTTGAAA

Downstream 100 bases:

>100_bases
CCTGAAAAGTTTTTGTTTGAATTAATAGAAGTTTTAACTAAAGATGGCAGTTATTCTTTAAGAAGTGAGTTTTTTCAAGA
GAACTTCCATAGTTTATTGG

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MNNIRTIKGGVNLKGKVKVPGDKSISHRALIIGSIANGETTIEGFLHSEDPLSTADCLRKLGVNIPEIKKNEPFTISGLG
LDGLKEPKEILNCGNSGTTMRLLMGLLAGQEDKNFILTGDISLNERPMGRVGKPLSLMGGKIFGREKGNKAPISIDGNKL
KGCVIGTPVASAQVKSAILLAGLKASGTTSVIEPASSRDHTERMLKAFGADISVRGELGRNVVIKSGGKLIGQRILIPGD
ISSASFWMIAASIVPNSEVLIQNVGLNPTRTGILNVMDSMGCNYEILDKSTIAGEPIGSIKVKSSNNLKSFTIEGDILPK
LIDEIPILTVAACFCNGVSEIKDAQELRVKETDRLKVMARQLQKFGAEVTEKEDGLIINGQSKFNSAEVDSETDHRVAMS
LAIASLLAKGTSKIMRADAASVSYPTFWEDLATLTN

Sequences:

>Translated_436_residues
MNNIRTIKGGVNLKGKVKVPGDKSISHRALIIGSIANGETTIEGFLHSEDPLSTADCLRKLGVNIPEIKKNEPFTISGLG
LDGLKEPKEILNCGNSGTTMRLLMGLLAGQEDKNFILTGDISLNERPMGRVGKPLSLMGGKIFGREKGNKAPISIDGNKL
KGCVIGTPVASAQVKSAILLAGLKASGTTSVIEPASSRDHTERMLKAFGADISVRGELGRNVVIKSGGKLIGQRILIPGD
ISSASFWMIAASIVPNSEVLIQNVGLNPTRTGILNVMDSMGCNYEILDKSTIAGEPIGSIKVKSSNNLKSFTIEGDILPK
LIDEIPILTVAACFCNGVSEIKDAQELRVKETDRLKVMARQLQKFGAEVTEKEDGLIINGQSKFNSAEVDSETDHRVAMS
LAIASLLAKGTSKIMRADAASVSYPTFWEDLATLTN
>Mature_436_residues
MNNIRTIKGGVNLKGKVKVPGDKSISHRALIIGSIANGETTIEGFLHSEDPLSTADCLRKLGVNIPEIKKNEPFTISGLG
LDGLKEPKEILNCGNSGTTMRLLMGLLAGQEDKNFILTGDISLNERPMGRVGKPLSLMGGKIFGREKGNKAPISIDGNKL
KGCVIGTPVASAQVKSAILLAGLKASGTTSVIEPASSRDHTERMLKAFGADISVRGELGRNVVIKSGGKLIGQRILIPGD
ISSASFWMIAASIVPNSEVLIQNVGLNPTRTGILNVMDSMGCNYEILDKSTIAGEPIGSIKVKSSNNLKSFTIEGDILPK
LIDEIPILTVAACFCNGVSEIKDAQELRVKETDRLKVMARQLQKFGAEVTEKEDGLIINGQSKFNSAEVDSETDHRVAMS
LAIASLLAKGTSKIMRADAASVSYPTFWEDLATLTN

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=442, Percent_Identity=29.185520361991, Blast_Score=137, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6320332, Length=461, Percent_Identity=25.3796095444685, Blast_Score=115, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46409; Mature: 46409

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNIRTIKGGVNLKGKVKVPGDKSISHRALIIGSIANGETTIEGFLHSEDPLSTADCLRK
CCCCEEEECCCCEEEEEECCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHH
LGVNIPEIKKNEPFTISGLGLDGLKEPKEILNCGNSGTTMRLLMGLLAGQEDKNFILTGD
HCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEEC
ISLNERPMGRVGKPLSLMGGKIFGREKGNKAPISIDGNKLKGCVIGTPVASAQVKSAILL
CCCCCCCCCCCCCCHHHHCCEEECCCCCCCCCEEECCCCCCEEEEECCCCHHHHHHHHHE
AGLKASGTTSVIEPASSRDHTERMLKAFGADISVRGELGRNVVIKSGGKLIGQRILIPGD
EECCCCCCCHHCCCCCCCHHHHHHHHHHCCCEEEECCCCCEEEEECCCCEECCEEEECCC
ISSASFWMIAASIVPNSEVLIQNVGLNPTRTGILNVMDSMGCNYEILDKSTIAGEPIGSI
CCCCEEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCE
KVKSSNNLKSFTIEGDILPKLIDEIPILTVAACFCNGVSEIKDAQELRVKETDRLKVMAR
EEECCCCCEEEEECCCHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHH
QLQKFGAEVTEKEDGLIINGQSKFNSAEVDSETDHRVAMSLAIASLLAKGTSKIMRADAA
HHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
SVSYPTFWEDLATLTN
CCCCCHHHHHHHHHCC
>Mature Secondary Structure
MNNIRTIKGGVNLKGKVKVPGDKSISHRALIIGSIANGETTIEGFLHSEDPLSTADCLRK
CCCCEEEECCCCEEEEEECCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHH
LGVNIPEIKKNEPFTISGLGLDGLKEPKEILNCGNSGTTMRLLMGLLAGQEDKNFILTGD
HCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEEC
ISLNERPMGRVGKPLSLMGGKIFGREKGNKAPISIDGNKLKGCVIGTPVASAQVKSAILL
CCCCCCCCCCCCCCHHHHCCEEECCCCCCCCCEEECCCCCCEEEEECCCCHHHHHHHHHE
AGLKASGTTSVIEPASSRDHTERMLKAFGADISVRGELGRNVVIKSGGKLIGQRILIPGD
EECCCCCCCHHCCCCCCCHHHHHHHHHHCCCEEEECCCCCEEEEECCCCEECCEEEECCC
ISSASFWMIAASIVPNSEVLIQNVGLNPTRTGILNVMDSMGCNYEILDKSTIAGEPIGSI
CCCCEEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCE
KVKSSNNLKSFTIEGDILPKLIDEIPILTVAACFCNGVSEIKDAQELRVKETDRLKVMAR
EEECCCCCEEEEECCCHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHH
QLQKFGAEVTEKEDGLIINGQSKFNSAEVDSETDHRVAMSLAIASLLAKGTSKIMRADAA
HHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
SVSYPTFWEDLATLTN
CCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA