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The map label for this gene is glmU [H]

Identifier: 123968202

GI number: 123968202

Start: 591343

End: 592692

Strand: Reverse

Name: glmU [H]

Synonym: A9601_06671

Alternate gene names: 123968202

Gene position: 592692-591343 (Counterclockwise)

Preceding gene: 123968203

Following gene: 123968197

Centisome position: 35.49

GC content: 31.93

Gene sequence:

>1350_bases
ATGTTAAGTGTTGCGATATTAGCGGCAGGCAAGGGCACTAGGATGGAAAGCTCATTACCAAAAGTTTTACACAAAATTTC
CGGCAAAAGTCTTCTACAAAGAGTAATTGATTCATGTGCCGAATTAAAACCTGATAAAATTTTCGTTATCACTGGACACA
AATCAAAAGAAGTACAAAAGTCAATCCCAAAAGATAAAAAAATCCATGTTGTTGTTCAAGAACCTCAATCAGGAACGGGT
CATGCTATCCAGGTTCTTTGTAGTGAAGTAAAAAAACATGAAGGAAAACTTTTGGTACTTAACGGTGATGTGCCACTCAT
TAGGCCTACTACTCTAAAGAGACTTTTGTATTTACACGATTCAAAAAATGCTGATGTTTCTTTAATTACCACAAAGAAAA
CAAATCCTCATGGATATGGCAGAGTTTTTTTGAATGGGGATTTTATAGAGAGAATTGTTGAAGAAAAAGATTGCAATGAA
CTAGAAAGAGAAAATCCATTAATAAATGCAGGTGTTTACTGTTTTAATTGGGGTAACTTATCAGAAATAATTAATACCTT
GCAAAGCAATAATAATCAAAAAGAGATTTACTTAACAGATACAATTTCTTTGCTAAAAAATTCTTTAAGTCTCGAGGTGG
AGGATAATGGAGAGCTTCAAGGAATTAATAACAGAATTCATCTATCAGAGTGCGAGGAATGTATTCAAAATTCAATTAAA
GAGAAGCATATGCTTAATGGTGTAACTTTTATAAATAAAGCAAGTTGTTCAATTAGTGAAGAAGCTGAAATTGGAAAGGA
TGTAATCATAGAGGCTAATACACATATAAGAGGAAATACAAAAATAAATAGTCATTGCATTATCGGTCCAAATACTTTTA
TTGAAAATTCCAATGTGGGATTACAATGTGAAATTTCAAACTCTACTGTTTATGATTCTCAGGTAATGGATCATATAAAA
ATTGGCCCTTATAGTCATATAAGACCTAATTCCAAAATATCTTCATACAGCAAAATTGGTAATTTTGTTGAGATCAAAAA
TAGTCAACTAGAGGAAGAAACTAAAGTAAACCATCTAAGTTATATTGGTGATTCCATTATTGGAAGATCTACAAATATTG
GAGCAGGAACTATTACTGCAAATTTTGATGGACAGAAAAAATATCAAACAAAAATTGGTAAAAATTCCAGTATTGGAGCA
AACACAGTTTTTGTAGCACCAATAAATCTAGGGGAATCAGTAACAACAGGTGCTGGTTCAGTGATCACAAAGGACTCTAA
AGATAATTCATTAGCGATATCAAGAACTAAGCAAGTAAATATAGAGAATTGGAAAAAGAAGAAATCCTGA

Upstream 100 bases:

>100_bases
ATTCTCAAATCTATTATCTACAAATAAATGGAGGGAGAAGTGGGGAATGTGACGAAGTTATCCGTTAAGAGTTAGATTTA
AATTAGGATTTCAAATAAAC

Downstream 100 bases:

>100_bases
TCTAGTTAATTAATTCAATAATTTTATCAAGTTGCCAAAATCTGCTTCCTTTTACAAGAATAGAATCGCCTTTTTTTGTA
GATTTGTTTATCTCTTGAGG

Product: bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MLSVAILAAGKGTRMESSLPKVLHKISGKSLLQRVIDSCAELKPDKIFVITGHKSKEVQKSIPKDKKIHVVVQEPQSGTG
HAIQVLCSEVKKHEGKLLVLNGDVPLIRPTTLKRLLYLHDSKNADVSLITTKKTNPHGYGRVFLNGDFIERIVEEKDCNE
LERENPLINAGVYCFNWGNLSEIINTLQSNNNQKEIYLTDTISLLKNSLSLEVEDNGELQGINNRIHLSECEECIQNSIK
EKHMLNGVTFINKASCSISEEAEIGKDVIIEANTHIRGNTKINSHCIIGPNTFIENSNVGLQCEISNSTVYDSQVMDHIK
IGPYSHIRPNSKISSYSKIGNFVEIKNSQLEEETKVNHLSYIGDSIIGRSTNIGAGTITANFDGQKKYQTKIGKNSSIGA
NTVFVAPINLGESVTTGAGSVITKDSKDNSLAISRTKQVNIENWKKKKS

Sequences:

>Translated_449_residues
MLSVAILAAGKGTRMESSLPKVLHKISGKSLLQRVIDSCAELKPDKIFVITGHKSKEVQKSIPKDKKIHVVVQEPQSGTG
HAIQVLCSEVKKHEGKLLVLNGDVPLIRPTTLKRLLYLHDSKNADVSLITTKKTNPHGYGRVFLNGDFIERIVEEKDCNE
LERENPLINAGVYCFNWGNLSEIINTLQSNNNQKEIYLTDTISLLKNSLSLEVEDNGELQGINNRIHLSECEECIQNSIK
EKHMLNGVTFINKASCSISEEAEIGKDVIIEANTHIRGNTKINSHCIIGPNTFIENSNVGLQCEISNSTVYDSQVMDHIK
IGPYSHIRPNSKISSYSKIGNFVEIKNSQLEEETKVNHLSYIGDSIIGRSTNIGAGTITANFDGQKKYQTKIGKNSSIGA
NTVFVAPINLGESVTTGAGSVITKDSKDNSLAISRTKQVNIENWKKKKS
>Mature_449_residues
MLSVAILAAGKGTRMESSLPKVLHKISGKSLLQRVIDSCAELKPDKIFVITGHKSKEVQKSIPKDKKIHVVVQEPQSGTG
HAIQVLCSEVKKHEGKLLVLNGDVPLIRPTTLKRLLYLHDSKNADVSLITTKKTNPHGYGRVFLNGDFIERIVEEKDCNE
LERENPLINAGVYCFNWGNLSEIINTLQSNNNQKEIYLTDTISLLKNSLSLEVEDNGELQGINNRIHLSECEECIQNSIK
EKHMLNGVTFINKASCSISEEAEIGKDVIIEANTHIRGNTKINSHCIIGPNTFIENSNVGLQCEISNSTVYDSQVMDHIK
IGPYSHIRPNSKISSYSKIGNFVEIKNSQLEEETKVNHLSYIGDSIIGRSTNIGAGTITANFDGQKKYQTKIGKNSSIGA
NTVFVAPINLGESVTTGAGSVITKDSKDNSLAISRTKQVNIENWKKKKS

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=451, Percent_Identity=38.3592017738359, Blast_Score=313, Evalue=1e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 49501; Mature: 49501

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSVAILAAGKGTRMESSLPKVLHKISGKSLLQRVIDSCAELKPDKIFVITGHKSKEVQK
CEEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHH
SIPKDKKIHVVVQEPQSGTGHAIQVLCSEVKKHEGKLLVLNGDVPLIRPTTLKRLLYLHD
HCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCEECHHHHHHEEEEEC
SKNADVSLITTKKTNPHGYGRVFLNGDFIERIVEEKDCNELERENPLINAGVYCFNWGNL
CCCCCEEEEEECCCCCCCCEEEEECHHHHHHHHHHCCHHHHHHCCCEEECCEEEEECCCH
SEIINTLQSNNNQKEIYLTDTISLLKNSLSLEVEDNGELQGINNRIHLSECEECIQNSIK
HHHHHHHHCCCCCEEEEEEHHHHHHHCCEEEEECCCCCEECCCCEEEHHHHHHHHHHHHH
EKHMLNGVTFINKASCSISEEAEIGKDVIIEANTHIRGNTKINSHCIIGPNTFIENSNVG
HHHHHCCEEEEECCCCCCCCHHHCCCEEEEEECCEEECCCEECCEEEECCCCEEECCCCE
LQCEISNSTVYDSQVMDHIKIGPYSHIRPNSKISSYSKIGNFVEIKNSQLEEETKVNHLS
EEEEECCCEEEHHHHHHHEECCCCCCCCCCCCHHHHHHCCCEEEECCCCCCHHHHHHHHH
YIGDSIIGRSTNIGAGTITANFDGQKKYQTKIGKNSSIGANTVFVAPINLGESVTTGAGS
HHHHHHCCCCCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCC
VITKDSKDNSLAISRTKQVNIENWKKKKS
EEEECCCCCCEEEEEEEECCCHHHHCCCC
>Mature Secondary Structure
MLSVAILAAGKGTRMESSLPKVLHKISGKSLLQRVIDSCAELKPDKIFVITGHKSKEVQK
CEEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHH
SIPKDKKIHVVVQEPQSGTGHAIQVLCSEVKKHEGKLLVLNGDVPLIRPTTLKRLLYLHD
HCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCEECHHHHHHEEEEEC
SKNADVSLITTKKTNPHGYGRVFLNGDFIERIVEEKDCNELERENPLINAGVYCFNWGNL
CCCCCEEEEEECCCCCCCCEEEEECHHHHHHHHHHCCHHHHHHCCCEEECCEEEEECCCH
SEIINTLQSNNNQKEIYLTDTISLLKNSLSLEVEDNGELQGINNRIHLSECEECIQNSIK
HHHHHHHHCCCCCEEEEEEHHHHHHHCCEEEEECCCCCEECCCCEEEHHHHHHHHHHHHH
EKHMLNGVTFINKASCSISEEAEIGKDVIIEANTHIRGNTKINSHCIIGPNTFIENSNVG
HHHHHCCEEEEECCCCCCCCHHHCCCEEEEEECCEEECCCEECCEEEECCCCEEECCCCE
LQCEISNSTVYDSQVMDHIKIGPYSHIRPNSKISSYSKIGNFVEIKNSQLEEETKVNHLS
EEEEECCCEEEHHHHHHHEECCCCCCCCCCCCHHHHHHCCCEEEECCCCCCHHHHHHHHH
YIGDSIIGRSTNIGAGTITANFDGQKKYQTKIGKNSSIGANTVFVAPINLGESVTTGAGS
HHHHHHCCCCCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCC
VITKDSKDNSLAISRTKQVNIENWKKKKS
EEEECCCCCCEEEEEEEECCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA