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The map label for this gene is pyrH [H]

Identifier: 123968113

GI number: 123968113

Start: 503513

End: 504217

Strand: Reverse

Name: pyrH [H]

Synonym: A9601_05781

Alternate gene names: 123968113

Gene position: 504217-503513 (Counterclockwise)

Preceding gene: 123968114

Following gene: 123968112

Centisome position: 30.19

GC content: 39.29

Gene sequence:

>705_bases
ATGACTTACAAAAGAGTTCTCTTAAAACTTAGTGGTGAAGCACTAATGGGTGAAAAACCTTATGGTATTGATCCTGCTAT
AGTTCAGTCAATCGCGGAGGATGTTTCAAAAGTAGTCGAAAATAATGTACAACTTGCAATAGTTGTTGGGGGTGGGAATA
TTTTTAGGGGGCTTAAAGGGTCTGCAGATGGCATGGATAGAGCGACGGCTGATTATGTTGGAATGCTAGCAACAGTAATG
AATGCAATTTCACTTCAAGATGGTCTTGAAAGAGTTGGAGTTGCAACCAGAGTGCAAACAGCCATCGAAATGCAGGAAAT
TGCCGAACCCTACATCAGAAGAAGGGCCATGAGGCACCTAGAAAAAGGTAGAGTTGTAGTCTTCGGAGGTGGATGCGGAA
ATCCATTTTTTACAACTGATACTACGGCAGCTTTGAGGGCAGCAGAGATTAACGCTGAAGTTGTTATGAAGGCTACTAAG
GTTGATGGAGTATACGATCGTGATCCAAATCAATTTAAAGAAGCAAAAAAATATTCCTCTCTCAGTTATCAACAAGTTCT
TAGTGATGAAATTGCAGTAATGGACAGTACTGCAATTGCACTTTGCAAAGATAATAATATCCCAATTATGGTTTTTGATA
TATTCAAAAAAGGGAATATTTCTAGAGCTGTTGCTGGTGAGCCAATAGGCTCTTTAATTAGTTAA

Upstream 100 bases:

>100_bases
TTTAGTCAGATTTAGAAATGTTTAAAGACGCAAGCAATATCTGAACAAACAATAAATTTGGTGCATTTACTTGCTAATGT
CTTAAAAGTACAATTATTGA

Downstream 100 bases:

>100_bases
AGATCATTTAATTTTTTTAATTATGAAAGAAAAAGAAATTCAAGAAAATATGAATAAAAGTATTGAAGCTACACAAAGAA
ACTTTAATACAATTAGAACA

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MTYKRVLLKLSGEALMGEKPYGIDPAIVQSIAEDVSKVVENNVQLAIVVGGGNIFRGLKGSADGMDRATADYVGMLATVM
NAISLQDGLERVGVATRVQTAIEMQEIAEPYIRRRAMRHLEKGRVVVFGGGCGNPFFTTDTTAALRAAEINAEVVMKATK
VDGVYDRDPNQFKEAKKYSSLSYQQVLSDEIAVMDSTAIALCKDNNIPIMVFDIFKKGNISRAVAGEPIGSLIS

Sequences:

>Translated_234_residues
MTYKRVLLKLSGEALMGEKPYGIDPAIVQSIAEDVSKVVENNVQLAIVVGGGNIFRGLKGSADGMDRATADYVGMLATVM
NAISLQDGLERVGVATRVQTAIEMQEIAEPYIRRRAMRHLEKGRVVVFGGGCGNPFFTTDTTAALRAAEINAEVVMKATK
VDGVYDRDPNQFKEAKKYSSLSYQQVLSDEIAVMDSTAIALCKDNNIPIMVFDIFKKGNISRAVAGEPIGSLIS
>Mature_233_residues
TYKRVLLKLSGEALMGEKPYGIDPAIVQSIAEDVSKVVENNVQLAIVVGGGNIFRGLKGSADGMDRATADYVGMLATVMN
AISLQDGLERVGVATRVQTAIEMQEIAEPYIRRRAMRHLEKGRVVVFGGGCGNPFFTTDTTAALRAAEINAEVVMKATKV
DGVYDRDPNQFKEAKKYSSLSYQQVLSDEIAVMDSTAIALCKDNNIPIMVFDIFKKGNISRAVAGEPIGSLIS

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=232, Percent_Identity=46.1206896551724, Blast_Score=221, Evalue=4e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 25268; Mature: 25137

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYKRVLLKLSGEALMGEKPYGIDPAIVQSIAEDVSKVVENNVQLAIVVGGGNIFRGLKG
CCHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHCCCC
SADGMDRATADYVGMLATVMNAISLQDGLERVGVATRVQTAIEMQEIAEPYIRRRAMRHL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKGRVVVFGGGCGNPFFTTDTTAALRAAEINAEVVMKATKVDGVYDRDPNQFKEAKKYSS
HCCCEEEEECCCCCCCCCCCHHHHHHHHHCCHHHEEEEHHCCCCCCCCCHHHHHHHHHHC
LSYQQVLSDEIAVMDSTAIALCKDNNIPIMVFDIFKKGNISRAVAGEPIGSLIS
HHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEECCCCCCHHHCCCCHHHHCC
>Mature Secondary Structure 
TYKRVLLKLSGEALMGEKPYGIDPAIVQSIAEDVSKVVENNVQLAIVVGGGNIFRGLKG
CHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHCCCC
SADGMDRATADYVGMLATVMNAISLQDGLERVGVATRVQTAIEMQEIAEPYIRRRAMRHL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKGRVVVFGGGCGNPFFTTDTTAALRAAEINAEVVMKATKVDGVYDRDPNQFKEAKKYSS
HCCCEEEEECCCCCCCCCCCHHHHHHHHHCCHHHEEEEHHCCCCCCCCCHHHHHHHHHHC
LSYQQVLSDEIAVMDSTAIALCKDNNIPIMVFDIFKKGNISRAVAGEPIGSLIS
HHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEECCCCCCHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA