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The map label for this gene is frr [H]

Identifier: 123968112

GI number: 123968112

Start: 502942

End: 503490

Strand: Reverse

Name: frr [H]

Synonym: A9601_05771

Alternate gene names: 123968112

Gene position: 503490-502942 (Counterclockwise)

Preceding gene: 123968113

Following gene: 123968111

Centisome position: 30.15

GC content: 30.6

Gene sequence:

>549_bases
ATGAAAGAAAAAGAAATTCAAGAAAATATGAATAAAAGTATTGAAGCTACACAAAGAAACTTTAATACAATTAGAACAGG
TAGAGCTAATGCTTCATTGTTAGACAGAGTAAGTGTTGAGTACTACGGAGCAGAAACACCAATCAAATCGCTTGCCACCA
TAAGCACTGTTGATTCACAAACAATCTCAATACAACCTTTCGATATTTCATGTTTACAAGCTATTGAGAAATCTATTTCT
ATGAGTGATTTAGGTATTACTCCAAATAATGATGGGAAAGTAATAAGAATAAATGTTCCTCCTTTAACAGAAGAAAGAAG
AAAAGAATTTTGTAAATTAGCCTCTAAATACGCTGAGGAAGGAAAAGTAGCCTTGAGAAATATCAGAAGAGATGCTGTTG
ATAAAGAAAAAAAAGACGAAAAAGATGGCCTTATTTCAATTGACGAATCGAGAGATAATCAATCTGAAATTCAGAAAATT
ACTGATAAATATATCGCTTTAATAGAAACTAAATTGTCTGAAAAAGAGAAGGAAATTCTAAAAGTTTGA

Upstream 100 bases:

>100_bases
ATGGTTTTTGATATATTCAAAAAAGGGAATATTTCTAGAGCTGTTGCTGGTGAGCCAATAGGCTCTTTAATTAGTTAAAG
ATCATTTAATTTTTTTAATT

Downstream 100 bases:

>100_bases
TAGAATTTGATGTTGTAATAATTGGTGGAGGTCTATCAGGATCTTCCACTGCTCTTAACCTATCAAAGAAAGGATATTCA
GTTTTAATTATTGAAAAAGA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MKEKEIQENMNKSIEATQRNFNTIRTGRANASLLDRVSVEYYGAETPIKSLATISTVDSQTISIQPFDISCLQAIEKSIS
MSDLGITPNNDGKVIRINVPPLTEERRKEFCKLASKYAEEGKVALRNIRRDAVDKEKKDEKDGLISIDESRDNQSEIQKI
TDKYIALIETKLSEKEKEILKV

Sequences:

>Translated_182_residues
MKEKEIQENMNKSIEATQRNFNTIRTGRANASLLDRVSVEYYGAETPIKSLATISTVDSQTISIQPFDISCLQAIEKSIS
MSDLGITPNNDGKVIRINVPPLTEERRKEFCKLASKYAEEGKVALRNIRRDAVDKEKKDEKDGLISIDESRDNQSEIQKI
TDKYIALIETKLSEKEKEILKV
>Mature_182_residues
MKEKEIQENMNKSIEATQRNFNTIRTGRANASLLDRVSVEYYGAETPIKSLATISTVDSQTISIQPFDISCLQAIEKSIS
MSDLGITPNNDGKVIRINVPPLTEERRKEFCKLASKYAEEGKVALRNIRRDAVDKEKKDEKDGLISIDESRDNQSEIQKI
TDKYIALIETKLSEKEKEILKV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=177, Percent_Identity=29.9435028248588, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1786368, Length=178, Percent_Identity=47.752808988764, Blast_Score=165, Evalue=1e-42,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20638; Mature: 20638

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKEIQENMNKSIEATQRNFNTIRTGRANASLLDRVSVEYYGAETPIKSLATISTVDSQ
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
TISIQPFDISCLQAIEKSISMSDLGITPNNDGKVIRINVPPLTEERRKEFCKLASKYAEE
EEEECCCCHHHHHHHHHHCCHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
GKVALRNIRRDAVDKEKKDEKDGLISIDESRDNQSEIQKITDKYIALIETKLSEKEKEIL
HHHHHHHHHHHHHCHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KV
CC
>Mature Secondary Structure
MKEKEIQENMNKSIEATQRNFNTIRTGRANASLLDRVSVEYYGAETPIKSLATISTVDSQ
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
TISIQPFDISCLQAIEKSISMSDLGITPNNDGKVIRINVPPLTEERRKEFCKLASKYAEE
EEEECCCCHHHHHHHHHHCCHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
GKVALRNIRRDAVDKEKKDEKDGLISIDESRDNQSEIQKITDKYIALIETKLSEKEKEIL
HHHHHHHHHHHHHCHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KV
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA