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The map label for this gene is gpmB [H]

Identifier: 123968106

GI number: 123968106

Start: 495625

End: 496953

Strand: Reverse

Name: gpmB [H]

Synonym: A9601_05711

Alternate gene names: 123968106

Gene position: 496953-495625 (Counterclockwise)

Preceding gene: 123968111

Following gene: 123968100

Centisome position: 29.76

GC content: 31.08

Gene sequence:

>1329_bases
ATGACTATAAGATTAGTTTTAGTTAGGCATGGACTAAGCAGTTTCAATGCAAAAGGATTAATTCAAGGAAGAACAGACGA
TTCATTATTAACCGATGAAGGATACAAACAAGCCCGAAAAGCAGGAAAAGCATTATCAAAAATAAACTTCGATAAAATTT
ATTCCTCCCCACTTGTGAGAGCGGCAGAGACTGCAAAAACAATTAAAAAGACCTTCAAAAAAGAACAAAATATTGTATTC
GACGATAATTTGCTAGAGGTAGATCTTGGTGAATGGTCTGGTCTAAAAATTGATGAAATAAAAAAGAAATTTCCAGAAAT
TTACCCTATATGGAAAAATGATCCAGAAAATCTAATCTTAGAAAGAAAAGATTATAAAACTTATAAACCAATTCAAGAGT
TATTTTTGCAAGCAACAAATTTTGTAGAAAATATTTTAAAAATTTATCTAGACAAAGATGATGTAAATATTTTAGTTGTA
GGACATAATGCAATTCTCAGATGTTTAATACTCTTTTTAATAGGAAAGCCTAAGCAAGGTTTTAGAAAAATAAGATTAGA
AAATGCTTCTTTCTCAATACTCAATATTTCAAGGAAAGATAACTCTTACAAGACCCAAATTGAATGCTTAAATCAAACTT
CTCATCTGAATAAAAATATTCCAAATCAAATTGGTGATTCTAGAATATTTCTAATAAGACATGGTGAAACTAACTGGAAC
AAAGAAGGTAGATTTCAAGGGCAAATTGATATCCCTTTAAATGAAAACGGAAAAAATCAAGCTAGAAAGACTTTTGAATA
TTTGAGAAATATTTCTTTCAATAAGGCATTTTCAAGTTCAATGCATAGGCCTTTTGAGACTGCACAAATAATCCTTCAAA
ATAGAAAAGATTTAAAAATAGAAAGAACAGATTCACTTATAGAAATTAGTCACGGATTATGGGAGGGTAAACTGGAAGCA
GAAATTAGAGAAGAGTGGCCTGCTTTACTAAAAAATTGGCATGATAAACCAGAAGAAGTAATAATGCCCGAAGGTGAATC
TATAAAAGATGTATCACAAAGATCCGTAGAAGCTTTTGACAAAATCTGTTTATCTCAAAAGGATAATGATCTAAGCCTTC
TAGTTGCTCATGATGCAGTCAATAAAACTCTAATTTGTAATATCCTTGGCATTAATTATTCAAATATTTGGATGATAAAA
CAAGGGAATGGTGGCATAACTATAATCGATCTTTTTAATGATCCCAACAAGCCCCCTGTGATTAGCGCTCTAAACATTAC
AACACACCTAGGAGGAATAATTGATTCAACCGCTTCAGGCGCACTTTAA

Upstream 100 bases:

>100_bases
GAAAACTATAGTTAGTTATCATTGAATTTCCTTATTTCTATGTATCTATTTTAATCACGCCATGAGATGATTAAATTATC
TTAATTTTCAAATTTATATA

Downstream 100 bases:

>100_bases
ATTAAAACCCTTTTTAAAATTTATTTCATCAAGTTAGATGCTGAAAAAGGGTATTAATTATTGAAAAAGCCAACTTGACT
AAGAGGCCAAAATCTTAAAT

Product: putative alpha-ribazole-5'-P phosphatase

Products: NA

Alternate protein names: PGAM; Phosphoglyceromutase [H]

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MTIRLVLVRHGLSSFNAKGLIQGRTDDSLLTDEGYKQARKAGKALSKINFDKIYSSPLVRAAETAKTIKKTFKKEQNIVF
DDNLLEVDLGEWSGLKIDEIKKKFPEIYPIWKNDPENLILERKDYKTYKPIQELFLQATNFVENILKIYLDKDDVNILVV
GHNAILRCLILFLIGKPKQGFRKIRLENASFSILNISRKDNSYKTQIECLNQTSHLNKNIPNQIGDSRIFLIRHGETNWN
KEGRFQGQIDIPLNENGKNQARKTFEYLRNISFNKAFSSSMHRPFETAQIILQNRKDLKIERTDSLIEISHGLWEGKLEA
EIREEWPALLKNWHDKPEEVIMPEGESIKDVSQRSVEAFDKICLSQKDNDLSLLVAHDAVNKTLICNILGINYSNIWMIK
QGNGGITIIDLFNDPNKPPVISALNITTHLGGIIDSTASGAL

Sequences:

>Translated_442_residues
MTIRLVLVRHGLSSFNAKGLIQGRTDDSLLTDEGYKQARKAGKALSKINFDKIYSSPLVRAAETAKTIKKTFKKEQNIVF
DDNLLEVDLGEWSGLKIDEIKKKFPEIYPIWKNDPENLILERKDYKTYKPIQELFLQATNFVENILKIYLDKDDVNILVV
GHNAILRCLILFLIGKPKQGFRKIRLENASFSILNISRKDNSYKTQIECLNQTSHLNKNIPNQIGDSRIFLIRHGETNWN
KEGRFQGQIDIPLNENGKNQARKTFEYLRNISFNKAFSSSMHRPFETAQIILQNRKDLKIERTDSLIEISHGLWEGKLEA
EIREEWPALLKNWHDKPEEVIMPEGESIKDVSQRSVEAFDKICLSQKDNDLSLLVAHDAVNKTLICNILGINYSNIWMIK
QGNGGITIIDLFNDPNKPPVISALNITTHLGGIIDSTASGAL
>Mature_441_residues
TIRLVLVRHGLSSFNAKGLIQGRTDDSLLTDEGYKQARKAGKALSKINFDKIYSSPLVRAAETAKTIKKTFKKEQNIVFD
DNLLEVDLGEWSGLKIDEIKKKFPEIYPIWKNDPENLILERKDYKTYKPIQELFLQATNFVENILKIYLDKDDVNILVVG
HNAILRCLILFLIGKPKQGFRKIRLENASFSILNISRKDNSYKTQIECLNQTSHLNKNIPNQIGDSRIFLIRHGETNWNK
EGRFQGQIDIPLNENGKNQARKTFEYLRNISFNKAFSSSMHRPFETAQIILQNRKDLKIERTDSLIEISHGLWEGKLEAE
IREEWPALLKNWHDKPEEVIMPEGESIKDVSQRSVEAFDKICLSQKDNDLSLLVAHDAVNKTLICNILGINYSNIWMIKQ
GNGGITIIDLFNDPNKPPVISALNITTHLGGIIDSTASGAL

Specific function: Converts N1-(5-Phospho-Alpha-D-Ribosyl)-5,6- Dimethylbenzimidazole Into N1-Alpha-D-Ribosyl-5,6- Dimethylbenzimidazole; Involved In The Assembly Of The Nucleotide Loop Of Cobalamin. [C]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. GpmB subfamily [H]

Homologues:

Organism=Homo sapiens, GI9966849, Length=137, Percent_Identity=35.036496350365, Blast_Score=80, Evalue=6e-15,
Organism=Escherichia coli, GI1786857, Length=184, Percent_Identity=27.7173913043478, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790856, Length=164, Percent_Identity=31.7073170731707, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR023086 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 50470; Mature: 50338

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRLVLVRHGLSSFNAKGLIQGRTDDSLLTDEGYKQARKAGKALSKINFDKIYSSPLVR
CEEEEEEEECCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHCCHHHH
AAETAKTIKKTFKKEQNIVFDDNLLEVDLGEWSGLKIDEIKKKFPEIYPIWKNDPENLIL
HHHHHHHHHHHHHHCCCEEECCCEEEEECCCCCCCCHHHHHHHCCCEECCCCCCCHHEEE
ERKDYKTYKPIQELFLQATNFVENILKIYLDKDDVNILVVGHNAILRCLILFLIGKPKQG
ECCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEECCHHHHHHHHHHHHCCCHHH
FRKIRLENASFSILNISRKDNSYKTQIECLNQTSHLNKNIPNQIGDSRIFLIRHGETNWN
HHEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHCCCCEEEEEECCCCCCC
KEGRFQGQIDIPLNENGKNQARKTFEYLRNISFNKAFSSSMHRPFETAQIILQNRKDLKI
CCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHCCCCCEE
ERTDSLIEISHGLWEGKLEAEIREEWPALLKNWHDKPEEVIMPEGESIKDVSQRSVEAFD
ECCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHH
KICLSQKDNDLSLLVAHDAVNKTLICNILGINYSNIWMIKQGNGGITIIDLFNDPNKPPV
HHHHCCCCCCEEEEEEECCCCCEEEEEEEECCCCEEEEEEECCCCEEEEECCCCCCCCCE
ISALNITTHLGGIIDSTASGAL
EEEEEHHHHHCHHHCCCCCCCC
>Mature Secondary Structure 
TIRLVLVRHGLSSFNAKGLIQGRTDDSLLTDEGYKQARKAGKALSKINFDKIYSSPLVR
EEEEEEEECCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHCCHHHH
AAETAKTIKKTFKKEQNIVFDDNLLEVDLGEWSGLKIDEIKKKFPEIYPIWKNDPENLIL
HHHHHHHHHHHHHHCCCEEECCCEEEEECCCCCCCCHHHHHHHCCCEECCCCCCCHHEEE
ERKDYKTYKPIQELFLQATNFVENILKIYLDKDDVNILVVGHNAILRCLILFLIGKPKQG
ECCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEECCHHHHHHHHHHHHCCCHHH
FRKIRLENASFSILNISRKDNSYKTQIECLNQTSHLNKNIPNQIGDSRIFLIRHGETNWN
HHEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHCCCCEEEEEECCCCCCC
KEGRFQGQIDIPLNENGKNQARKTFEYLRNISFNKAFSSSMHRPFETAQIILQNRKDLKI
CCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHCCCCCEE
ERTDSLIEISHGLWEGKLEAEIREEWPALLKNWHDKPEEVIMPEGESIKDVSQRSVEAFD
ECCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHH
KICLSQKDNDLSLLVAHDAVNKTLICNILGINYSNIWMIKQGNGGITIIDLFNDPNKPPV
HHHHCCCCCCEEEEEEECCCCCEEEEEEEECCCCEEEEEEECCCCEEEEECCCCCCCCCE
ISALNITTHLGGIIDSTASGAL
EEEEEHHHHHCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA