Click here to switch to the map view.

The map label for this gene is pgsA [H]

Identifier: 123966018

GI number: 123966018

Start: 706994

End: 707536

Strand: Direct

Name: pgsA [H]

Synonym: P9515_07831

Alternate gene names: 123966018

Gene position: 706994-707536 (Clockwise)

Preceding gene: 123966016

Following gene: 123966020

Centisome position: 41.49

GC content: 22.84

Gene sequence:

>543_bases
TTGTTAAACAAAAATAAAATTTTTAAAAGATTTTACTTAAATATTCCAAATATTTTGACAATATCTAGATTATTTCTAGT
ATTTCCTCTAATCCTATTTTTAGAACTAACCAAAACCAAATTTGTTTTTGCTTTAATTGTTCTTGGTGGAATAACTGATT
ATTATGATGGATTTTTTGCAAGAAAATTAAATTTAAAAACTAAGTTTGGAGCTATTCTTGACCCATTATCAGATAAAATA
TTTCTGTTAATACCATTAATATGGCTTTGTAAGATTAAGTTAATACCTTTTTGGTCATTATCAATAATATTATTTAGAGA
ATTAATAATATCTGCATTAAGAACAAGGATAAAAGATGGTTTGCCAGCCTCTCAGCTAGGAAAATATAAAACTGTTTCTT
TCTTTATTTCATTATTATTATTTTTTCTACCATTTGAAATAGATTCATTTTCTAATTTAGGAATAATATTTTATTGGCTA
GGGTTTATTTTATCTCTTATAACTTTAATAGATTATTTAAGAGCTAAAAAGAACTTTATCTGA

Upstream 100 bases:

>100_bases
AAAATATGATGATAGCGGTTTGAAAAAGTTTTCAAATTCTTTAGGATTTTGTTAGAACCTAAAGTTAGACAAAAGTGTAA
AAATTATTTTATAAAAAAAA

Downstream 100 bases:

>100_bases
GTTGTTATCAAATTCCTCGTCTTTTTTAAGATCATAATCATTAATAAAACTGTCTTTCAAACCTCTCAATAAATCAAATT
TTGGTTCCCAATTTAAATCA

Product: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MLNKNKIFKRFYLNIPNILTISRLFLVFPLILFLELTKTKFVFALIVLGGITDYYDGFFARKLNLKTKFGAILDPLSDKI
FLLIPLIWLCKIKLIPFWSLSIILFRELIISALRTRIKDGLPASQLGKYKTVSFFISLLLFFLPFEIDSFSNLGIIFYWL
GFILSLITLIDYLRAKKNFI

Sequences:

>Translated_180_residues
MLNKNKIFKRFYLNIPNILTISRLFLVFPLILFLELTKTKFVFALIVLGGITDYYDGFFARKLNLKTKFGAILDPLSDKI
FLLIPLIWLCKIKLIPFWSLSIILFRELIISALRTRIKDGLPASQLGKYKTVSFFISLLLFFLPFEIDSFSNLGIIFYWL
GFILSLITLIDYLRAKKNFI
>Mature_180_residues
MLNKNKIFKRFYLNIPNILTISRLFLVFPLILFLELTKTKFVFALIVLGGITDYYDGFFARKLNLKTKFGAILDPLSDKI
FLLIPLIWLCKIKLIPFWSLSIILFRELIISALRTRIKDGLPASQLGKYKTVSFFISLLLFFLPFEIDSFSNLGIIFYWL
GFILSLITLIDYLRAKKNFI

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=176, Percent_Identity=32.3863636363636, Blast_Score=90, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320059, Length=116, Percent_Identity=39.6551724137931, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24650130, Length=99, Percent_Identity=38.3838383838384, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24650126, Length=99, Percent_Identity=38.3838383838384, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24650128, Length=99, Percent_Identity=38.3838383838384, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21034; Mature: 21034

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNKNKIFKRFYLNIPNILTISRLFLVFPLILFLELTKTKFVFALIVLGGITDYYDGFFA
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKLNLKTKFGAILDPLSDKIFLLIPLIWLCKIKLIPFWSLSIILFRELIISALRTRIKDG
HHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
LPASQLGKYKTVSFFISLLLFFLPFEIDSFSNLGIIFYWLGFILSLITLIDYLRAKKNFI
CCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLNKNKIFKRFYLNIPNILTISRLFLVFPLILFLELTKTKFVFALIVLGGITDYYDGFFA
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKLNLKTKFGAILDPLSDKIFLLIPLIWLCKIKLIPFWSLSIILFRELIISALRTRIKDG
HHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
LPASQLGKYKTVSFFISLLLFFLPFEIDSFSNLGIIFYWLGFILSLITLIDYLRAKKNFI
CCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]