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The map label for this gene is muT4

Identifier: 121639819

GI number: 121639819

Start: 4356440

End: 4357186

Strand: Direct

Name: muT4

Synonym: BCG_3965

Alternate gene names: 121639819

Gene position: 4356440-4357186 (Clockwise)

Preceding gene: 121639789

Following gene: 121639820

Centisome position: 99.59

GC content: 69.08

Gene sequence:

>747_bases
GTGTCCGACGGCGAACAAGCCAAATCACGTCGACGCCGGGGGCGGCGCCGCGGGCGGCGCGCTGCGGCTACAGCCGAGAA
TCACATGGACGCCCAACCGGCCGGCGACGCCACCCCGACCCCGGCAACGGCGAAGCGGTCCCGGTCCCGCTCACCTCGTC
GCGGGTCGACTCGGATGCGCACCGTGCACGAAACATCGGCTGGAGGGTTGGTCATTGACGGTATCGACGGTCCACGAGAC
GCGCAGGTCGCGGCTCTGATCGGCCGCGTCGACCGGCGCGGCCGGCTGCTGTGGTCGCTACCCAAGGGGCACATCGAGTT
GGGCGAGACCGCCGAGCAGACCGCCATCCGCGAGGTCGCCGAGGAGACCGGCATCCGCGGCAGTGTGCTTGCCGCGCTGG
GGCGCATCGACTACTGGTTCGTCACCGACGGCCGGCGGGTGCACAAGACCGTCCACCATTATTTGATGCGGTTTTTAGGC
GGAGAGCTGTCCGACGAAGACCTCGAGGTAGCCGAGGTAGCCTGGGTGCCGATCCGGGAACTGCCGTCTCGACTGGCCTA
CGCCGACGAACGTCGACTAGCCGAGGTGGCCGACGAACTGATCGACAAGCTGCAGAGCGACGGCCCCGCCGCGCTTCCGC
CGCTACCACCCAGCTCGCCTCGTCGACGGCCGCAAACGCATTCACGCGCTCGTCATGCCGATGACTCAGCACCGGGTCAG
CACAACGGTCCCGGGCCGGGGCCGTGA

Upstream 100 bases:

>100_bases
GCCCCGCTCCCTCGCCCAACGAATAAGTCCTGGCCGACGATGGGCGCTCAGACGGCGAGTACATCGGGAACACCCGCCCG
TACCAGCTACTATCGCTGGG

Downstream 100 bases:

>100_bases
CCGCACTGCAACTCCGCTGGGCCGCTTTGGCGCGCGTCACCTCAGCGATCGGCGTCGTGGCCGGCCTCGGGATGGCGCTC
ACGGTACCGTCGGCGGCACC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MSDGEQAKSRRRRGRRRGRRAAATAENHMDAQPAGDATPTPATAKRSRSRSPRRGSTRMRTVHETSAGGLVIDGIDGPRD
AQVAALIGRVDRRGRLLWSLPKGHIELGETAEQTAIREVAEETGIRGSVLAALGRIDYWFVTDGRRVHKTVHHYLMRFLG
GELSDEDLEVAEVAWVPIRELPSRLAYADERRLAEVADELIDKLQSDGPAALPPLPPSSPRRRPQTHSRARHADDSAPGQ
HNGPGPGP

Sequences:

>Translated_248_residues
MSDGEQAKSRRRRGRRRGRRAAATAENHMDAQPAGDATPTPATAKRSRSRSPRRGSTRMRTVHETSAGGLVIDGIDGPRD
AQVAALIGRVDRRGRLLWSLPKGHIELGETAEQTAIREVAEETGIRGSVLAALGRIDYWFVTDGRRVHKTVHHYLMRFLG
GELSDEDLEVAEVAWVPIRELPSRLAYADERRLAEVADELIDKLQSDGPAALPPLPPSSPRRRPQTHSRARHADDSAPGQ
HNGPGPGP
>Mature_247_residues
SDGEQAKSRRRRGRRRGRRAAATAENHMDAQPAGDATPTPATAKRSRSRSPRRGSTRMRTVHETSAGGLVIDGIDGPRDA
QVAALIGRVDRRGRLLWSLPKGHIELGETAEQTAIREVAEETGIRGSVLAALGRIDYWFVTDGRRVHKTVHHYLMRFLGG
ELSDEDLEVAEVAWVPIRELPSRLAYADERRLAEVADELIDKLQSDGPAALPPLPPSSPRRRPQTHSRARHADDSAPGQH
NGPGPGP

Specific function: May be involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine, 8-oxo-dGTP) from DNA and the nucleotide pool. In vitro has dATPase rather than 8-oxo-dGTPase activity

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MUTT4_MYCTU (O05437)

Other databases:

- EMBL:   BX842584
- EMBL:   AE000516
- PIR:   E70600
- RefSeq:   NP_218425.1
- RefSeq:   NP_338578.1
- HSSP:   Q9U2M7
- ProteinModelPortal:   O05437
- EnsemblBacteria:   EBMYCT00000001517
- EnsemblBacteria:   EBMYCT00000072511
- GeneID:   886242
- GeneID:   926654
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT4027
- KEGG:   mtu:Rv3908
- TIGR:   MT4027
- TubercuList:   Rv3908
- GeneTree:   EBGT00050000015833
- HOGENOM:   HBG741910
- OMA:   ARSAENH
- ProtClustDB:   CLSK792805
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- Gene3D:   G3DSA:3.90.79.10
- PRINTS:   PR00502

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: NA

Molecular weight: Translated: 27172; Mature: 27041

Theoretical pI: Translated: 10.86; Mature: 10.86

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDGEQAKSRRRRGRRRGRRAAATAENHMDAQPAGDATPTPATAKRSRSRSPRRGSTRMR
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHH
TVHETSAGGLVIDGIDGPRDAQVAALIGRVDRRGRLLWSLPKGHIELGETAEQTAIREVA
HHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCCEECCCHHHHHHHHHHH
EETGIRGSVLAALGRIDYWFVTDGRRVHKTVHHYLMRFLGGELSDEDLEVAEVAWVPIRE
HHHCCCHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHH
LPSRLAYADERRLAEVADELIDKLQSDGPAALPPLPPSSPRRRPQTHSRARHADDSAPGQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCC
HNGPGPGP
CCCCCCCC
>Mature Secondary Structure 
SDGEQAKSRRRRGRRRGRRAAATAENHMDAQPAGDATPTPATAKRSRSRSPRRGSTRMR
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHH
TVHETSAGGLVIDGIDGPRDAQVAALIGRVDRRGRLLWSLPKGHIELGETAEQTAIREVA
HHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCCEECCCHHHHHHHHHHH
EETGIRGSVLAALGRIDYWFVTDGRRVHKTVHHYLMRFLGGELSDEDLEVAEVAWVPIRE
HHHCCCHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHH
LPSRLAYADERRLAEVADELIDKLQSDGPAALPPLPPSSPRRRPQTHSRARHADDSAPGQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCC
HNGPGPGP
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036