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The map label for this gene is rnz [H]

Identifier: 121639713

GI number: 121639713

Start: 4222281

End: 4223408

Strand: Direct

Name: rnz [H]

Synonym: BCG_3858

Alternate gene names: 121639713

Gene position: 4222281-4223408 (Clockwise)

Preceding gene: 121639712

Following gene: 121639714

Centisome position: 96.52

GC content: 61.26

Gene sequence:

>1128_bases
ATGCTGCTCGGTATGCACCAGGCCGGCCATGTTGGCACACACGAACGGCGCGCAGCCGCAACGAGGCGGTCCGCCCTGAC
TGCGGCAGGGTTAGCCGTCGTCGGCGCAGGGGTGTTGGGCGCGTCGGCGTGCAGTCCACAAAAGTCTCCTCAGCCATCAT
CACCCCGGTTGCCCGACAATGCGCTGATCACGCTCGGGGTGGCCGCCGGCCCGCCGCCTACGCCCAGCAGAGTAGGAATC
TCGTCGGTGCTGAAAATTGGCCGCGATCTGTACGTGATCGATTGCGGCCTGGGCTCGCTGAACGCATTCACCAACGCGGG
CCTGCAATTCGACGATCTCAAAGCCATGTTTATCACCCACTTGCACACCGACCACATCGTCGACTACTACAACTTCTTTC
TCTCCGGTGGCTTCCTTGCCCCACCCGGTCGAGCGCCGGTCCTGGTCTATGGTCCGGGCCCAGCTGGGGGTTTGCCGCCA
AGTGAAGTCGGCAACCCGAATCCAGCCACCGTCAACCCCGCCAACCCGACACCGGGCCTTGCCGCGGCCACCGAAGCGCT
GCATCGAGCGTTCGCTTACACCAGCAACATCTTCATCCGCGACTACGGCATTGACAACGTTGCGGACCTGGTTAAAGTCA
CGGAGATCGGGCTACCACCAGGATCGGACTACCGCAACAGAGCGCCAAAGATGAGCCCGTTCTCGGTCGCATCGGACGAC
AACGTTTCCGTCACCGCAACGCTGGTCTCCCACTACGACGTCTACCCAGCGTTCGGATTCCGCTTCGATCTGAAGAAATC
GGGTGTGTCCGTTACCTTCTCGGGTGACACCACTAAGTCCGACAACCTGATTACCCTCGCTCAAGGCACTGACATTCTGG
TCCACGAGGCGGTGTTCAGCCTCGATACGGCTTACTTTGGCAACGCTTTCCCCCCGAACTATCTGGTGAACTCACACATC
TCCGCAGAGCAGGTGGGGGAGGTGGCCGCAGCGGCCAAGCCCAAACAATTGATCCTGAGCCACTACGCCCCTGACGACCT
ACCCGACTCGCAGTGGCTCGACAAGATCAAGAAGAATTACTCGGGCATGACCACCATCGCGCGGGACGGCCAGGTCTTCG
CCCTCTGA

Upstream 100 bases:

>100_bases
TGGTCACCGGGCAAGATCCGAATTGGTCCATAGCGTCAGGCTCCGCAGTCGATAGCGGCACGATGTTCGTCATTAGACGG
CCCCATCAGTTAGGCCTCCT

Downstream 100 bases:

>100_bases
TCCGTTAGCGGTAGCGCCCCGTTCGACGATCGCTGCCTAGAGCTAGACATATATAAAACCTATGCAATAGGGTCGCGGCA
TGCCCGAGTACGACCTAGAG

Product: hypothetical protein

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MLLGMHQAGHVGTHERRAAATRRSALTAAGLAVVGAGVLGASACSPQKSPQPSSPRLPDNALITLGVAAGPPPTPSRVGI
SSVLKIGRDLYVIDCGLGSLNAFTNAGLQFDDLKAMFITHLHTDHIVDYYNFFLSGGFLAPPGRAPVLVYGPGPAGGLPP
SEVGNPNPATVNPANPTPGLAAATEALHRAFAYTSNIFIRDYGIDNVADLVKVTEIGLPPGSDYRNRAPKMSPFSVASDD
NVSVTATLVSHYDVYPAFGFRFDLKKSGVSVTFSGDTTKSDNLITLAQGTDILVHEAVFSLDTAYFGNAFPPNYLVNSHI
SAEQVGEVAAAAKPKQLILSHYAPDDLPDSQWLDKIKKNYSGMTTIARDGQVFAL

Sequences:

>Translated_375_residues
MLLGMHQAGHVGTHERRAAATRRSALTAAGLAVVGAGVLGASACSPQKSPQPSSPRLPDNALITLGVAAGPPPTPSRVGI
SSVLKIGRDLYVIDCGLGSLNAFTNAGLQFDDLKAMFITHLHTDHIVDYYNFFLSGGFLAPPGRAPVLVYGPGPAGGLPP
SEVGNPNPATVNPANPTPGLAAATEALHRAFAYTSNIFIRDYGIDNVADLVKVTEIGLPPGSDYRNRAPKMSPFSVASDD
NVSVTATLVSHYDVYPAFGFRFDLKKSGVSVTFSGDTTKSDNLITLAQGTDILVHEAVFSLDTAYFGNAFPPNYLVNSHI
SAEQVGEVAAAAKPKQLILSHYAPDDLPDSQWLDKIKKNYSGMTTIARDGQVFAL
>Mature_375_residues
MLLGMHQAGHVGTHERRAAATRRSALTAAGLAVVGAGVLGASACSPQKSPQPSSPRLPDNALITLGVAAGPPPTPSRVGI
SSVLKIGRDLYVIDCGLGSLNAFTNAGLQFDDLKAMFITHLHTDHIVDYYNFFLSGGFLAPPGRAPVLVYGPGPAGGLPP
SEVGNPNPATVNPANPTPGLAAATEALHRAFAYTSNIFIRDYGIDNVADLVKVTEIGLPPGSDYRNRAPKMSPFSVASDD
NVSVTATLVSHYDVYPAFGFRFDLKKSGVSVTFSGDTTKSDNLITLAQGTDILVHEAVFSLDTAYFGNAFPPNYLVNSHI
SAEQVGEVAAAAKPKQLILSHYAPDDLPDSQWLDKIKKNYSGMTTIARDGQVFAL

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR013471 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 39456; Mature: 39456

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLGMHQAGHVGTHERRAAATRRSALTAAGLAVVGAGVLGASACSPQKSPQPSSPRLPDN
CEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
ALITLGVAAGPPPTPSRVGISSVLKIGRDLYVIDCGLGSLNAFTNAGLQFDDLKAMFITH
CEEEEEECCCCCCCCCCCCHHHHHHCCCCEEEEEECCCCHHHHHHCCCCHHHHHHHHHHH
LHTDHIVDYYNFFLSGGFLAPPGRAPVLVYGPGPAGGLPPSEVGNPNPATVNPANPTPGL
HHHHHHHHHHHHHHCCCEECCCCCCCEEEECCCCCCCCCCHHCCCCCCCCCCCCCCCCCH
AAATEALHRAFAYTSNIFIRDYGIDNVADLVKVTEIGLPPGSDYRNRAPKMSPFSVASDD
HHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCCCCCCCCHHHCCCCCCCCEECCCC
NVSVTATLVSHYDVYPAFGFRFDLKKSGVSVTFSGDTTKSDNLITLAQGTDILVHEAVFS
CCEEEEEEEECCCCCCCCCEEEEECCCCEEEEECCCCCCCCCEEEEECCCCEEHHHHHHH
LDTAYFGNAFPPNYLVNSHISAEQVGEVAAAAKPKQLILSHYAPDDLPDSQWLDKIKKNY
HHHHHCCCCCCCCCEECCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHCC
SGMTTIARDGQVFAL
CCCEEEECCCEEEEC
>Mature Secondary Structure
MLLGMHQAGHVGTHERRAAATRRSALTAAGLAVVGAGVLGASACSPQKSPQPSSPRLPDN
CEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
ALITLGVAAGPPPTPSRVGISSVLKIGRDLYVIDCGLGSLNAFTNAGLQFDDLKAMFITH
CEEEEEECCCCCCCCCCCCHHHHHHCCCCEEEEEECCCCHHHHHHCCCCHHHHHHHHHHH
LHTDHIVDYYNFFLSGGFLAPPGRAPVLVYGPGPAGGLPPSEVGNPNPATVNPANPTPGL
HHHHHHHHHHHHHHCCCEECCCCCCCEEEECCCCCCCCCCHHCCCCCCCCCCCCCCCCCH
AAATEALHRAFAYTSNIFIRDYGIDNVADLVKVTEIGLPPGSDYRNRAPKMSPFSVASDD
HHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCCCCCCCCHHHCCCCCCCCEECCCC
NVSVTATLVSHYDVYPAFGFRFDLKKSGVSVTFSGDTTKSDNLITLAQGTDILVHEAVFS
CCEEEEEEEECCCCCCCCCEEEEECCCCEEEEECCCCCCCCCEEEEECCCCEEHHHHHHH
LDTAYFGNAFPPNYLVNSHISAEQVGEVAAAAKPKQLILSHYAPDDLPDSQWLDKIKKNY
HHHHHCCCCCCCCCEECCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHCC
SGMTTIARDGQVFAL
CCCEEEECCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]