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The map label for this gene is PPE61

Identifier: 121639451

GI number: 121639451

Start: 3948235

End: 3949455

Strand: Direct

Name: PPE61

Synonym: BCG_3596

Alternate gene names: 121639451

Gene position: 3948235-3949455 (Clockwise)

Preceding gene: 121639446

Following gene: 121639456

Centisome position: 90.26

GC content: 66.5

Gene sequence:

>1221_bases
ATGTTCATGGATTTCGCGATGCTTCCGCCGGAAGTCAACTCGACACGGATGTATAGCGGGCCGGGAGCGGGCTCGTTGTG
GGCCGCCGCCGCCGCCTGGGATCAGGTGTCGGCGGAATTGCAGTCGGCGGCGGAGACCTACCGCTCGGTGATCGCCAGCC
TCACCGGCTGGCAATGGCTGGGTCCATCGTCTGTGAGGATGGGTGCGGCGGTCACCCCGTATGTTGAGTGGCTGACCACC
ACCGCCGCGCAGGCAAGGCAGACGGCCACCCAGATCACCGCGGCCGCGACCGGATTTGAGCAGGCGTTCGCCATGACGGT
GCCGCCACCGGCAATCATGGCCAACCGTGCACAGGTGCTATCGCTGATAGCGACCAACTTTTTCGGCCAGAACACCGCGG
CGATTGCGGCCCTGGAGACCCAGTACGCCGAGATGTGGGAACAGGACGCCACCGCCATGTACGACTACGCGGCCACCTCG
GCGGCAGCGCGGACTTTGACACCATTTACCTCCCCGCAGCAAGACACCAACTCAGCCGGTCTGCCGGCGCAAAGCGCCGA
AGTCAGCCGCGCGACCGCCAACGCCGGCGCCGCCGACGGCAACTGGCTGGGAAACCTCCTGGAAGAAATCGGAATACTGC
TGCTGCCGATCGCGCCCGAGCTGACACCCTTTTTCCTGGAGGCGGGCGAAATCGTCAATGCGATACCTTTCCCGAGCATC
GTCGGGGACGAGTTCTGTTTGCTCGACGGCCTACTGGCTTGGTACGCAACGATCGGCTCGATCAACAACATCAATTCGAT
GGGTACCGGCATCATTGGGGCCGAGAAGAATTTGGGGATCTTGCCCGAGCTAGGGAGCGCGGCTGCGGCGGCCGCTCCCC
CACCAGCCGACATCGCCCCGGCGTTCCTCGCGCCGCTGACCAGCATGGCCAAGTCACTATCGGACGGAGCACTACGCGGC
CCGGGCGAAGTTTCGGCCGCGATGCGCGGCGCGGGTACCATCGGGCAAATGTCGGTGCCGCCCGCCTGGAAGGCGCCCGC
GGTCACCACCGTCAGGGCGTTCGATGCCACCCCAATGACCACACTGCCCGGCGGCGACGCCCCCGCCGCTGGAGTGCCTG
GACTGCCCGGGATGCCAGCCTCGGGGGCCGGACGGGCTGGCGTGGTGCCCCGATACGGCGTACGGCTGACCGTGATGACA
CGTCCACTCTCGGGCGGGTGA

Upstream 100 bases:

>100_bases
TGCATCCGCGACAGCCACCCAATGACGCGCCTGCCGTTGCGATCTCAGCACTGACGGCAGCCCGGCCTATCCGCGACCAG
CTAGGGAAAGGCATTCGCAG

Downstream 100 bases:

>100_bases
CATCAGTGCGTGATGGCGGCGCACCTTGACCGTCGCGCATTGCGCTTCCAACACCAACGAACTGGGACTGCAGTAGTAGC
GCAACCGCGCTTGGAGCGGG

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGPSSVRMGAAVTPYVEWLTT
TAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATS
AAARTLTPFTSPQQDTNSAGLPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI
VGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAFLAPLTSMAKSLSDGALRG
PGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMTTLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMT
RPLSGG

Sequences:

>Translated_406_residues
MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGPSSVRMGAAVTPYVEWLTT
TAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATS
AAARTLTPFTSPQQDTNSAGLPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI
VGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAFLAPLTSMAKSLSDGALRG
PGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMTTLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMT
RPLSGG
>Mature_406_residues
MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGPSSVRMGAAVTPYVEWLTT
TAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATS
AAARTLTPFTSPQQDTNSAGLPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI
VGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAFLAPLTSMAKSLSDGALRG
PGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMTTLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMT
RPLSGG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPE61_MYCTU (Q6MWW4)

Other databases:

- EMBL:   BX842583
- EMBL:   AE000516
- PIR:   E70675
- RefSeq:   YP_177984.1
- HSSP:   Q79FE1
- ProteinModelPortal:   Q6MWW4
- SMR:   Q6MWW4
- EnsemblBacteria:   EBMYCT00000000234
- EnsemblBacteria:   EBMYCT00000084086
- GeneID:   888370
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtu:Rv3532
- TIGR:   MT3636
- TubercuList:   Rv3532
- GeneTree:   EBGT00050000014888
- HOGENOM:   HBG572308
- OMA:   ATIGSMQ
- ProtClustDB:   CLSK824815
- InterPro:   IPR022171
- InterPro:   IPR000030

Pfam domain/function: PF12484 PE_PPE_C; PF00823 PPE

EC number: NA

Molecular weight: Translated: 41550; Mature: 41550

Theoretical pI: Translated: 4.15; Mature: 4.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWL
CCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEECCCCHHHHHHHHHHH
SLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
LPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI
CCCCCHHHHHHHCCCCCCCCHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHCCCCCHH
VGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAP
HCCHHHHHHHHHHHHHHHCCCCCCHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCHH
AFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMT
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCC
TLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCC
>Mature Secondary Structure
MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWL
CCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEECCCCHHHHHHHHHHH
SLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
LPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI
CCCCCHHHHHHHCCCCCCCCHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHCCCCCHH
VGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAP
HCCHHHHHHHHHHHHHHHCCCCCCHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCHH
AFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMT
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCC
TLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036