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The map label for this gene is iunH [H]

Identifier: 121639317

GI number: 121639317

Start: 3794725

End: 3795651

Strand: Direct

Name: iunH [H]

Synonym: BCG_3462

Alternate gene names: 121639317

Gene position: 3794725-3795651 (Clockwise)

Preceding gene: 121639315

Following gene: 121639320

Centisome position: 86.75

GC content: 67.31

Gene sequence:

>927_bases
GTGAGCGTCGTATTCGCCGACGTCGACACCGGCATCGACGACGCGCTGGCCGTGATCTATCTGCTGGCCAGTCCCGACGC
CGATCTGGTCGGCATCGCCTCGACCGGCGGAAACATCGCGGTAGGTCAAGTGTGCGCGAACAACCTGAGCTTGCTCGAAT
TGTGCGGTGCCGCAGACATCCCCGTGTCCAAAGGCGCCGATGAGCCGCTCGGCGGCCGGTGGCCCGATCACCCAAAGTTT
CACGGCCCCAAGGGGATAGGCTATGCCGAGCTGCCGGCCAGCAATCGCCGGCTCACCGATTATGACGCCACGACGGCCTG
GATCGCGGCGGCGCACTCCCACGCCGGCGACCTGATCGGTCTGGTCACCGGCCCGCTGACCAACCTGGCGCTGGCGCTGC
GCGCCGAACCCGCGCTGCCGAGGCTGCTGCGCCGGCTGGTGATCATGGGCGGCATGTTCGACGGCCAGCCGATCACCGAA
TGGAACATCCGGGTGGATCCCGAGGCGGCCAGCGAGGTGTTCACCGCGTGGGCCGGACAACGACAACTGCCGATCGTGTG
CGGTTTGGATCTCACCCGGCGGGTCGCGATGACACCGGACATTCTCGCCCGGCTGGCGTCCGTCTGCGGCTCGTCTCCGG
TGATGCGGGTGATCGAGGACGCGCTGCGGTTCTACTTCGAGTCTCATGAGGCGCGCGGACATGGGTACCTGGCATATATG
CACGACCCGCTGGCCGCCGCGGTCGCAATGGACCCGGAACTCCTGACGACCCGGACCGCGACGGTGGATGTCGACCCGAC
GGGGGCGACGGTCACCGACTGGTCCGGGAAGCGAAATCCCAACGCGCGGATCGGCATGAGCGTCGATCCGGCGGTGTTCT
TCGACCGGTTCGTCGAACGGATCGGACGATTCGCGCGCCGAACGTGA

Upstream 100 bases:

>100_bases
AACAGCCGGAAGAAGTCGTCGGACAGGTCGTAGTGCGCCTGCACGTTGGCGAAGTGCGGCTTCAGCTCGTCGGGCATTGG
GATAGCGTATCGTCGTCGCG

Downstream 100 bases:

>100_bases
ACTGACGGCGGGATTTTCCCGAAATTCTCGCCCTGACGTCACGTTCGGCGCAAGTCATTCGTAGCTTCCCTCCAGATACC
ACCGCCGCTGCCGGTAGCAC

Product: putative nucleoside hydrolase iunH

Products: NA

Alternate protein names: Cytidine/uridine-specific hydrolase [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSVVFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVSKGADEPLGGRWPDHPKF
HGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVTGPLTNLALALRAEPALPRLLRRLVIMGGMFDGQPITE
WNIRVDPEAASEVFTAWAGQRQLPIVCGLDLTRRVAMTPDILARLASVCGSSPVMRVIEDALRFYFESHEARGHGYLAYM
HDPLAAAVAMDPELLTTRTATVDVDPTGATVTDWSGKRNPNARIGMSVDPAVFFDRFVERIGRFARRT

Sequences:

>Translated_308_residues
MSVVFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVSKGADEPLGGRWPDHPKF
HGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVTGPLTNLALALRAEPALPRLLRRLVIMGGMFDGQPITE
WNIRVDPEAASEVFTAWAGQRQLPIVCGLDLTRRVAMTPDILARLASVCGSSPVMRVIEDALRFYFESHEARGHGYLAYM
HDPLAAAVAMDPELLTTRTATVDVDPTGATVTDWSGKRNPNARIGMSVDPAVFFDRFVERIGRFARRT
>Mature_307_residues
SVVFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVSKGADEPLGGRWPDHPKFH
GPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVTGPLTNLALALRAEPALPRLLRRLVIMGGMFDGQPITEW
NIRVDPEAASEVFTAWAGQRQLPIVCGLDLTRRVAMTPDILARLASVCGSSPVMRVIEDALRFYFESHEARGHGYLAYMH
DPLAAAVAMDPELLTTRTATVDVDPTGATVTDWSGKRNPNARIGMSVDPAVFFDRFVERIGRFARRT

Specific function: Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively [H]

COG id: COG1957

COG function: function code F; Inosine-uridine nucleoside N-ribohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IUNH family. RihA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786871, Length=315, Percent_Identity=32.6984126984127, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788486, Length=318, Percent_Identity=28.3018867924528, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786213, Length=295, Percent_Identity=32.8813559322034, Blast_Score=103, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI32565474, Length=184, Percent_Identity=29.3478260869565, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17565698, Length=319, Percent_Identity=27.5862068965517, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320608, Length=327, Percent_Identity=27.217125382263, Blast_Score=86, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24583915, Length=187, Percent_Identity=31.5508021390374, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015910
- InterPro:   IPR023186
- InterPro:   IPR001910
- InterPro:   IPR022975 [H]

Pfam domain/function: PF01156 IU_nuc_hydro [H]

EC number: 3.2.2.-

Molecular weight: Translated: 32970; Mature: 32839

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVVFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADI
CEEEEEECCCCHHHHHHHHHHEECCCCCEEEEECCCCCEEEHHHHHCCCHHHHHCCCCCC
PVSKGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIG
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEECCCCCHHHHHHHHHCCCCCEEE
LVTGPLTNLALALRAEPALPRLLRRLVIMGGMFDGQPITEWNIRVDPEAASEVFTAWAGQ
EHHCCHHHHEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHCCC
RQLPIVCGLDLTRRVAMTPDILARLASVCGSSPVMRVIEDALRFYFESHEARGHGYLAYM
CCCCEEECCCHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEE
HDPLAAAVAMDPELLTTRTATVDVDPTGATVTDWSGKRNPNARIGMSVDPAVFFDRFVER
CCCHHHHHHCCCHHHEEEEEEEEECCCCCEEECCCCCCCCCCEECCCCCHHHHHHHHHHH
IGRFARRT
HHHHHCCC
>Mature Secondary Structure 
SVVFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADI
EEEEEECCCCHHHHHHHHHHEECCCCCEEEEECCCCCEEEHHHHHCCCHHHHHCCCCCC
PVSKGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIG
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEECCCCCHHHHHHHHHCCCCCEEE
LVTGPLTNLALALRAEPALPRLLRRLVIMGGMFDGQPITEWNIRVDPEAASEVFTAWAGQ
EHHCCHHHHEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHCCC
RQLPIVCGLDLTRRVAMTPDILARLASVCGSSPVMRVIEDALRFYFESHEARGHGYLAYM
CCCCEEECCCHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEE
HDPLAAAVAMDPELLTTRTATVDVDPTGATVTDWSGKRNPNARIGMSVDPAVFFDRFVER
CCCHHHHHHCCCHHHEEEEEEEEECCCCCEEECCCCCCCCCCEECCCCCHHHHHHHHHHH
IGRFARRT
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA