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The map label for this gene is aofH [H]

Identifier: 121639054

GI number: 121639054

Start: 3493697

End: 3495043

Strand: Direct

Name: aofH [H]

Synonym: BCG_3194

Alternate gene names: 121639054

Gene position: 3493697-3495043 (Clockwise)

Preceding gene: 121639053

Following gene: 121639058

Centisome position: 79.86

GC content: 68.45

Gene sequence:

>1347_bases
GTGACAAACCCACCGTGGACTGTCGATGTTGTCGTGGTGGGCGCGGGCTTCGCCGGGCTGGCCGCGGCCCGCGAGCTGAC
GCGACAGGGTCACGAGGTGCTGGTGTTCGAAGGCCGCGATCGGGTGGGCGGCCGCTCGTTAACCGGTCGCGTGGCAGGGG
TGCCCGCGGATATGGGCGGCTCGTTCATCGGCCCGACCCAAGACGCCGTGCTGGCGTTGGCCACCGAGCTGGGGATCCCG
ACAACCCCGACCCACCGCGACGGCCGAAACGTCATCCAGTGGCGGGGATCGGCACGCAGCTATCGTGGCACCATCCCCAA
GCTGTCGCTGACCGGGCTCATCGACATCGGCCGGTTGCGTTGGCAATTCGAGCGAATTGCCCGCGGCGTTCCGGTGGCCG
CCCCCTGGGATGCGCGGCGCGCGCGTGAACTCGACGACGTGTCGCTCGGGGAGTGGTTGCGCTTGGTGCGCGCCACATCG
TCCTCGCGGAACCTGATGGCCATCATGACCCGGGTGACCTGGGGTTGTGAGCCCGACGATGTCTCGATGCTGCACGCCGC
CCGCTACGTACGCGCGGCCGGCGGCCTGGACCGGCTGCTCGACGTCAAAAATGGTGCCCAGCAGGACCGTGTGCCGGGGG
GGACACAGCAGATCGCCCAGGCGGCCGCCGCCCAACTCGGCGCACGCGTCCTGCTCAACGCCGCGGTGCGTCGCATCGAC
CGGCACGGAGCGGGTGTGACGGTCACGTCCGATCAGGGTCAGGCCGAGGCCGGGTTCGTCATCGTCGCCATTCCACCGGC
CCATCGCGTGGCCATCGAGTTCGATCCCCCGCTGCCGCCGGAATATCAGCAGCTCGCCCACCATTGGCCGCAGGGCCGGC
TGAGCAAGGCCTACGCGGCCTATTCGACGCCGTTCTGGCGGGCCAGCGGGTATTCCGGCCAGGCGCTGTCCGATGAGGCG
CCGGTGTTCATCACCTTCGACGTCAGTCCGCACGCCGACGGGCCAGGCATTCTGATGGGGTTCGTCGATGCTCGCGGGTT
CGACTCGCTACCCATCGAAGAGCGCCGCCGCGATGCATTGCGCTGCTTTGCGTCGCTGTTCGGCGACGAAGCGCTCGACC
CCCTTGATTATGTTGACTATCGTTGGGGTACAGAGGAATTCGCGCCGGGTGGTCCGACCGCGGCGGTACCGCCGGGGTCG
TGGACGAAATACGGTCACTGGTTACGTGAGCCGGTCGGTCCGATTCACTGGGCGAGCACTGAGACCGCGGACGAATGGAC
CGGGTATTTCGACGGCGCCGTCAGATCCGGTCAGCGTGCCGCCGCCGAGGTCGCCGCCCTGCTATGA

Upstream 100 bases:

>100_bases
CGCGAGTCCAGGGTTCCTGGGCGCCGGCCGGGAAACGGCCCGAAAACGACGGCAGCCGGAATAGCCGACCGGAACCGCCG
AAATGCGGTTGACTAGAGCG

Downstream 100 bases:

>100_bases
GCTGATCCGCCGGTCCCGGACGTGCCGGGTCACCGATTCGGCCAGCGCCCGCAGGTGGCTGTTCACCTCTTGGTGCCGTT
CCAGCATCGAGCAGTGGCCG

Product: putative flavin-containing monoamine oxidase aofH

Products: RCHO; NH3; H2O2

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MTNPPWTVDVVVVGAGFAGLAAARELTRQGHEVLVFEGRDRVGGRSLTGRVAGVPADMGGSFIGPTQDAVLALATELGIP
TTPTHRDGRNVIQWRGSARSYRGTIPKLSLTGLIDIGRLRWQFERIARGVPVAAPWDARRARELDDVSLGEWLRLVRATS
SSRNLMAIMTRVTWGCEPDDVSMLHAARYVRAAGGLDRLLDVKNGAQQDRVPGGTQQIAQAAAAQLGARVLLNAAVRRID
RHGAGVTVTSDQGQAEAGFVIVAIPPAHRVAIEFDPPLPPEYQQLAHHWPQGRLSKAYAAYSTPFWRASGYSGQALSDEA
PVFITFDVSPHADGPGILMGFVDARGFDSLPIEERRRDALRCFASLFGDEALDPLDYVDYRWGTEEFAPGGPTAAVPPGS
WTKYGHWLREPVGPIHWASTETADEWTGYFDGAVRSGQRAAAEVAALL

Sequences:

>Translated_448_residues
MTNPPWTVDVVVVGAGFAGLAAARELTRQGHEVLVFEGRDRVGGRSLTGRVAGVPADMGGSFIGPTQDAVLALATELGIP
TTPTHRDGRNVIQWRGSARSYRGTIPKLSLTGLIDIGRLRWQFERIARGVPVAAPWDARRARELDDVSLGEWLRLVRATS
SSRNLMAIMTRVTWGCEPDDVSMLHAARYVRAAGGLDRLLDVKNGAQQDRVPGGTQQIAQAAAAQLGARVLLNAAVRRID
RHGAGVTVTSDQGQAEAGFVIVAIPPAHRVAIEFDPPLPPEYQQLAHHWPQGRLSKAYAAYSTPFWRASGYSGQALSDEA
PVFITFDVSPHADGPGILMGFVDARGFDSLPIEERRRDALRCFASLFGDEALDPLDYVDYRWGTEEFAPGGPTAAVPPGS
WTKYGHWLREPVGPIHWASTETADEWTGYFDGAVRSGQRAAAEVAALL
>Mature_447_residues
TNPPWTVDVVVVGAGFAGLAAARELTRQGHEVLVFEGRDRVGGRSLTGRVAGVPADMGGSFIGPTQDAVLALATELGIPT
TPTHRDGRNVIQWRGSARSYRGTIPKLSLTGLIDIGRLRWQFERIARGVPVAAPWDARRARELDDVSLGEWLRLVRATSS
SRNLMAIMTRVTWGCEPDDVSMLHAARYVRAAGGLDRLLDVKNGAQQDRVPGGTQQIAQAAAAQLGARVLLNAAVRRIDR
HGAGVTVTSDQGQAEAGFVIVAIPPAHRVAIEFDPPLPPEYQQLAHHWPQGRLSKAYAAYSTPFWRASGYSGQALSDEAP
VFITFDVSPHADGPGILMGFVDARGFDSLPIEERRRDALRCFASLFGDEALDPLDYVDYRWGTEEFAPGGPTAAVPPGSW
TKYGHWLREPVGPIHWASTETADEWTGYFDGAVRSGQRAAAEVAALL

Specific function: Unknown

COG id: COG1231

COG function: function code E; Monoamine oxidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flavin monoamine oxidase family [H]

Homologues:

Organism=Homo sapiens, GI4557735, Length=446, Percent_Identity=36.7713004484305, Blast_Score=281, Evalue=9e-76,
Organism=Homo sapiens, GI38202207, Length=437, Percent_Identity=36.3844393592677, Blast_Score=264, Evalue=1e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001613
- InterPro:   IPR002937 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: 1.4.3.4

Molecular weight: Translated: 48440; Mature: 48309

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPPWTVDVVVVGAGFAGLAAARELTRQGHEVLVFEGRDRVGGRSLTGRVAGVPADMGG
CCCCCEEEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCEEECCCHHCCC
SFIGPTQDAVLALATELGIPTTPTHRDGRNVIQWRGSARSYRGTIPKLSLTGLIDIGRLR
CCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEEECCEEHHHHHH
WQFERIARGVPVAAPWDARRARELDDVSLGEWLRLVRATSSSRNLMAIMTRVTWGCEPDD
HHHHHHHCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCH
VSMLHAARYVRAAGGLDRLLDVKNGAQQDRVPGGTQQIAQAAAAQLGARVLLNAAVRRID
HHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHGAGVTVTSDQGQAEAGFVIVAIPPAHRVAIEFDPPLPPEYQQLAHHWPQGRLSKAYAA
HCCCCEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHH
YSTPFWRASGYSGQALSDEAPVFITFDVSPHADGPGILMGFVDARGFDSLPIEERRRDAL
HCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHH
RCFASLFGDEALDPLDYVDYRWGTEEFAPGGPTAAVPPGSWTKYGHWLREPVGPIHWAST
HHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEECCC
ETADEWTGYFDGAVRSGQRAAAEVAALL
CCHHHHCCHHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure 
TNPPWTVDVVVVGAGFAGLAAARELTRQGHEVLVFEGRDRVGGRSLTGRVAGVPADMGG
CCCCEEEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCEEECCCHHCCC
SFIGPTQDAVLALATELGIPTTPTHRDGRNVIQWRGSARSYRGTIPKLSLTGLIDIGRLR
CCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEEECCEEHHHHHH
WQFERIARGVPVAAPWDARRARELDDVSLGEWLRLVRATSSSRNLMAIMTRVTWGCEPDD
HHHHHHHCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCH
VSMLHAARYVRAAGGLDRLLDVKNGAQQDRVPGGTQQIAQAAAAQLGARVLLNAAVRRID
HHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHGAGVTVTSDQGQAEAGFVIVAIPPAHRVAIEFDPPLPPEYQQLAHHWPQGRLSKAYAA
HCCCCEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHH
YSTPFWRASGYSGQALSDEAPVFITFDVSPHADGPGILMGFVDARGFDSLPIEERRRDAL
HCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHH
RCFASLFGDEALDPLDYVDYRWGTEEFAPGGPTAAVPPGSWTKYGHWLREPVGPIHWAST
HHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEECCC
ETADEWTGYFDGAVRSGQRAAAEVAALL
CCHHHHCCHHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RCH2NH2; H2O; O2

Specific reaction: RCH2NH2 + H2O + O2 = RCHO + NH3 + H2O2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]