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The map label for this gene is yfcH [C]

Identifier: 121638097

GI number: 121638097

Start: 2462270

End: 2463175

Strand: Direct

Name: yfcH [C]

Synonym: BCG_2232

Alternate gene names: 121638097

Gene position: 2462270-2463175 (Clockwise)

Preceding gene: 121638096

Following gene: 121638098

Centisome position: 56.29

GC content: 67.77

Gene sequence:

>906_bases
ATGGCCAACGCCGTTGTCGCGATCGCGGGTTCGTCTGGCTTGATCGGCTCTGCCCTGACCGCGGCGCTGCGCGCGGCCGA
CCACACGGTGCTGCGGATCGTGCGCCGGGCACCTGCGAATTCCGAAGAACTGCACTGGAATCCCGAAAGCGGCGAATTCG
ATCCGCACGCGCTCACCGATGTCGACGCCGTGGTCAACCTCTGCGGCGTCAACATCGCCCAGCGTCGGTGGTCGGGGGCT
TTCAAACAGAGCCTGCGCGACAGCCGGATCACACCCACCGAGGTGCTATCCGCCGCAGTCGCCGACGCCGGCGTCGCTAC
CTTGATCAACGCCAGCGCGGTGGGCTACTACGGAAACACCAAGGACCGGGTGGTCGACGAAAACGACTCGGCGGGAACAG
GTTTTCTGGCCCAGCTGTGCGTTGACTGGGAAACCGCCACGCGGCCGGCGCAGCAGAGCGGTGCCCGCGTGGTGCTGGCC
CGGACCGGAGTGGTGCTGTCTCCGGCGGGGGGCATGCTGCGACGCATGCGGCCACTGTTTTCGGTGGGCCTGGGCGCGCG
GCTGGGCAGCGGCCGGCAATATATGTCATGGATCAGCCTGGAGGACGAGGTGCGGGCGCTGCAGTTCGCTATCGCGCAGC
CCAACCTGTCCGGCCCGGTGAACTTGACCGGGCCGGCCCCCGTTACCAACGCCGAATTCACCACCGCGTTTGGCCGCGCC
GTCAACCGCCCTACCCCGCTGATGTTGCCTAGCGTCGCGGTACGCGCGGCGTTTGGTGAGTTCGCCGACGAGGGGTTGCT
CATTGGTCAGCGCGCCATCCCCTCCGCGCTGGAGCGAGCCGGATTTCAGTTCCACCACAACACCATTGGCGAGGCGCTCG
GCTACGCCACCACCCGGCCCGGCTAG

Upstream 100 bases:

>100_bases
ATGACCATCGGCTCATCGACGGCGCCGACGCCGGACGTTTCCTCACCACGATCAAGCACCGCCTCGAAGAGGGAGCGTTC
GAGGCCGATTTAGGACTGTG

Downstream 100 bases:

>100_bases
GCTTGACCCCGTCTGCCCAGCCGTGCGCTGGCGGCCGAGTAGCCTAGCTATCGTGACGGGTTCTATCCGGTCGAAGCTGT
CCGCGATCGACGTCCGCCAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MANAVVAIAGSSGLIGSALTAALRAADHTVLRIVRRAPANSEELHWNPESGEFDPHALTDVDAVVNLCGVNIAQRRWSGA
FKQSLRDSRITPTEVLSAAVADAGVATLINASAVGYYGNTKDRVVDENDSAGTGFLAQLCVDWETATRPAQQSGARVVLA
RTGVVLSPAGGMLRRMRPLFSVGLGARLGSGRQYMSWISLEDEVRALQFAIAQPNLSGPVNLTGPAPVTNAEFTTAFGRA
VNRPTPLMLPSVAVRAAFGEFADEGLLIGQRAIPSALERAGFQFHHNTIGEALGYATTRPG

Sequences:

>Translated_301_residues
MANAVVAIAGSSGLIGSALTAALRAADHTVLRIVRRAPANSEELHWNPESGEFDPHALTDVDAVVNLCGVNIAQRRWSGA
FKQSLRDSRITPTEVLSAAVADAGVATLINASAVGYYGNTKDRVVDENDSAGTGFLAQLCVDWETATRPAQQSGARVVLA
RTGVVLSPAGGMLRRMRPLFSVGLGARLGSGRQYMSWISLEDEVRALQFAIAQPNLSGPVNLTGPAPVTNAEFTTAFGRA
VNRPTPLMLPSVAVRAAFGEFADEGLLIGQRAIPSALERAGFQFHHNTIGEALGYATTRPG
>Mature_300_residues
ANAVVAIAGSSGLIGSALTAALRAADHTVLRIVRRAPANSEELHWNPESGEFDPHALTDVDAVVNLCGVNIAQRRWSGAF
KQSLRDSRITPTEVLSAAVADAGVATLINASAVGYYGNTKDRVVDENDSAGTGFLAQLCVDWETATRPAQQSGARVVLAR
TGVVLSPAGGMLRRMRPLFSVGLGARLGSGRQYMSWISLEDEVRALQFAIAQPNLSGPVNLTGPAPVTNAEFTTAFGRAV
NRPTPLMLPSVAVRAAFGEFADEGLLIGQRAIPSALERAGFQFHHNTIGEALGYATTRPG

Specific function: Unknown

COG id: COG1090

COG function: function code R; Predicted nucleoside-diphosphate sugar epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family. SDR39U1 subfamily

Homologues:

Organism=Homo sapiens, GI116812630, Length=293, Percent_Identity=34.4709897610922, Blast_Score=139, Evalue=2e-33,
Organism=Escherichia coli, GI1788642, Length=294, Percent_Identity=39.4557823129252, Blast_Score=189, Evalue=3e-49,
Organism=Drosophila melanogaster, GI28573846, Length=297, Percent_Identity=30.6397306397306, Blast_Score=150, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2216_MYCTU (P67232)

Other databases:

- EMBL:   BX842579
- EMBL:   AE000516
- PIR:   A70787
- RefSeq:   NP_216732.1
- RefSeq:   NP_336744.1
- ProteinModelPortal:   P67232
- EnsemblBacteria:   EBMYCT00000000360
- EnsemblBacteria:   EBMYCT00000072749
- GeneID:   887640
- GeneID:   924153
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2273
- KEGG:   mtu:Rv2216
- TIGR:   MT2273
- TubercuList:   Rv2216
- GeneTree:   EBGT00050000015197
- HOGENOM:   HBG462742
- OMA:   PPHTFIS
- ProtClustDB:   CLSK2299988
- InterPro:   IPR013549
- InterPro:   IPR001509
- InterPro:   IPR016040
- InterPro:   IPR010099
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR11092
- TIGRFAMs:   TIGR01777

Pfam domain/function: PF08338 DUF1731; PF01370 Epimerase

EC number: NA

Molecular weight: Translated: 31672; Mature: 31541

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANAVVAIAGSSGLIGSALTAALRAADHTVLRIVRRAPANSEELHWNPESGEFDPHALTD
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHH
VDAVVNLCGVNIAQRRWSGAFKQSLRDSRITPTEVLSAAVADAGVATLINASAVGYYGNT
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCC
KDRVVDENDSAGTGFLAQLCVDWETATRPAQQSGARVVLARTGVVLSPAGGMLRRMRPLF
CCCEECCCCCCCHHHHHHHHHCHHHHCCCHHHCCCEEEEEECCEEECCCCHHHHHHHHHH
SVGLGARLGSGRQYMSWISLEDEVRALQFAIAQPNLSGPVNLTGPAPVTNAEFTTAFGRA
HHCCCCCCCCCHHHHHHHCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHHH
VNRPTPLMLPSVAVRAAFGEFADEGLLIGQRAIPSALERAGFQFHHNTIGEALGYATTRP
HCCCCCCCHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHCCCEEHHHHHHHHHCCCCCCC
G
C
>Mature Secondary Structure 
ANAVVAIAGSSGLIGSALTAALRAADHTVLRIVRRAPANSEELHWNPESGEFDPHALTD
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHH
VDAVVNLCGVNIAQRRWSGAFKQSLRDSRITPTEVLSAAVADAGVATLINASAVGYYGNT
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCC
KDRVVDENDSAGTGFLAQLCVDWETATRPAQQSGARVVLARTGVVLSPAGGMLRRMRPLF
CCCEECCCCCCCHHHHHHHHHCHHHHCCCHHHCCCEEEEEECCEEECCCCHHHHHHHHHH
SVGLGARLGSGRQYMSWISLEDEVRALQFAIAQPNLSGPVNLTGPAPVTNAEFTTAFGRA
HHCCCCCCCCCHHHHHHHCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHHH
VNRPTPLMLPSVAVRAAFGEFADEGLLIGQRAIPSALERAGFQFHHNTIGEALGYATTRP
HCCCCCCCHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHCCCEEHHHHHHHHHCCCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036