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The map label for this gene is adoK

Identifier: 121638083

GI number: 121638083

Start: 2445697

End: 2446671

Strand: Reverse

Name: adoK

Synonym: BCG_2218c

Alternate gene names: 121638083

Gene position: 2446671-2445697 (Counterclockwise)

Preceding gene: 121638085

Following gene: 121638081

Centisome position: 55.93

GC content: 63.9

Gene sequence:

>975_bases
GTGACGATCGCGGTAACCGGTTCGATTGCGACCGACCATTTGATGCGGTTTCCAGGCCGATTTTCCGAGCAGCTACTGCC
CGAACACCTGCACAAGGTGTCGCTTAGCTTCCTAGTCGATGACTTGGTGATGCACCGCGGCGGCGTGGCCGGAAACATGG
CCTTCGCCATCGGTGTGCTAGGTGGCGAGGTCGCGCTAGTTGGGGCGGCAGGCGCCGACTTCGCCGATTATCGCGACTGG
CTGAAAGCCCGCGGTGTCAACTGCGACCACGTTCTGATCTCCGAGACCGCGCACACGGCGCGGTTTACCTGTACCACCGA
TGTCGACATGGCCCAGATCGCATCGTTCTACCCCGGGGCTATGTCGGAGGCACGTAACATCAAGCTTGCCGACGTGGTGT
CGGCCATCGGCAAGCCGGAGTTGGTGATCATCGGCGCCAACGACCCCGAGGCGATGTTCTTGCACACCGAGGAGTGTCGC
AAGCTGGGGCTGGCCTTCGCCGCCGATCCGTCTCAGCAGCTGGCGAGGCTGTCGGGTGAGGAAATTCGCAGGCTCGTCAA
CGGTGCTGCTTACTTGTTCACCAACGACTACGAATGGGATCTGCTGCTGTCCAAGACCGGCTGGTCAGAGGCCGATGTGA
TGGCGCAGATCGACCTGCGGGTGACCACATTGGGTCCTAAGGGTGTCGATTTGGTAGAACCTGACGGCACCACCATCCAC
GTCGGCGTGGTCCCCGAAACCAGCCAGACCGACCCCACCGGCGTCGGCGACGCGTTCCGCGCCGGTTTCCTGACTGGCCG
CAGTGCCGGACTAGGCCTGGAGCGTTCGGCGCAGCTGGGCTCGCTGGTTGCCGTGCTGGTGCTGGAGTCGACCGGAACTC
AGGAGTGGCAGTGGGACTACGAGGCCGCGGCCAGCAGGCTGGCTGGTGCTTACGGCGAGCACGCGGCCGCCGAGATCGTC
GCCGTGCTGGCCTAG

Upstream 100 bases:

>100_bases
AGCGCAACAGCTGCCGTCAGCTCTCAACGCGACGGGGCGGGCCGCGGCGCCGATAATGTTGAAAGACTAGGCAACCTTAG
GAACGAAGGACGGAGATTTT

Downstream 100 bases:

>100_bases
CCGCGGCTTGGCCTAGCCGCGGCACCGCCGAGCAGACGCGGAATCGCACCGTGTGGGCCCCGCCGATGCGATTCCGCGTC
TGCTCGCGAAGGGGCGGTTA

Product: adenosine kinase

Products: NA

Alternate protein names: AK

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MTIAVTGSIATDHLMRFPGRFSEQLLPEHLHKVSLSFLVDDLVMHRGGVAGNMAFAIGVLGGEVALVGAAGADFADYRDW
LKARGVNCDHVLISETAHTARFTCTTDVDMAQIASFYPGAMSEARNIKLADVVSAIGKPELVIIGANDPEAMFLHTEECR
KLGLAFAADPSQQLARLSGEEIRRLVNGAAYLFTNDYEWDLLLSKTGWSEADVMAQIDLRVTTLGPKGVDLVEPDGTTIH
VGVVPETSQTDPTGVGDAFRAGFLTGRSAGLGLERSAQLGSLVAVLVLESTGTQEWQWDYEAAASRLAGAYGEHAAAEIV
AVLA

Sequences:

>Translated_324_residues
MTIAVTGSIATDHLMRFPGRFSEQLLPEHLHKVSLSFLVDDLVMHRGGVAGNMAFAIGVLGGEVALVGAAGADFADYRDW
LKARGVNCDHVLISETAHTARFTCTTDVDMAQIASFYPGAMSEARNIKLADVVSAIGKPELVIIGANDPEAMFLHTEECR
KLGLAFAADPSQQLARLSGEEIRRLVNGAAYLFTNDYEWDLLLSKTGWSEADVMAQIDLRVTTLGPKGVDLVEPDGTTIH
VGVVPETSQTDPTGVGDAFRAGFLTGRSAGLGLERSAQLGSLVAVLVLESTGTQEWQWDYEAAASRLAGAYGEHAAAEIV
AVLA
>Mature_323_residues
TIAVTGSIATDHLMRFPGRFSEQLLPEHLHKVSLSFLVDDLVMHRGGVAGNMAFAIGVLGGEVALVGAAGADFADYRDWL
KARGVNCDHVLISETAHTARFTCTTDVDMAQIASFYPGAMSEARNIKLADVVSAIGKPELVIIGANDPEAMFLHTEECRK
LGLAFAADPSQQLARLSGEEIRRLVNGAAYLFTNDYEWDLLLSKTGWSEADVMAQIDLRVTTLGPKGVDLVEPDGTTIHV
GVVPETSQTDPTGVGDAFRAGFLTGRSAGLGLERSAQLGSLVAVLVLESTGTQEWQWDYEAAASRLAGAYGEHAAAEIVA
VLA

Specific function: ATP dependent phosphorylation of adenosine to monophosphate derivatives

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADOK_MYCBO (P83736)

Other databases:

- EMBL:   BX248341
- RefSeq:   NP_855874.1
- ProteinModelPortal:   P83736
- SMR:   P83736
- EnsemblBacteria:   EBMYCT00000016180
- GeneID:   1091347
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2225c
- GeneTree:   EBGT00050000016732
- HOGENOM:   HBG296008
- OMA:   FHPGAMS
- ProtClustDB:   CLSK872029
- BioCyc:   MBOV233413:MB2225C-MONOMER
- BRENDA:   2.7.1.20
- InterPro:   IPR011611
- InterPro:   IPR002173

Pfam domain/function: PF00294 PfkB

EC number: =2.7.1.20

Molecular weight: Translated: 34472; Mature: 34341

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00583 PFKB_KINASES_1; PS00584 PFKB_KINASES_2

Important sites: ACT_SITE 257-257

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIAVTGSIATDHLMRFPGRFSEQLLPEHLHKVSLSFLVDDLVMHRGGVAGNMAFAIGVL
CEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEE
GGEVALVGAAGADFADYRDWLKARGVNCDHVLISETAHTARFTCTTDVDMAQIASFYPGA
CCCEEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEECCCCHHHHHHHCCCC
MSEARNIKLADVVSAIGKPELVIIGANDPEAMFLHTEECRKLGLAFAADPSQQLARLSGE
HHHHCCCCHHHHHHHCCCCCEEEEECCCCCEEEEEHHHHHHHCCEEECCCHHHHHHCCHH
EIRRLVNGAAYLFTNDYEWDLLLSKTGWSEADVMAQIDLRVTTLGPKGVDLVEPDGTTIH
HHHHHHCCEEEEEECCCCEEEEEECCCCCCCCEEEEEEEEEEEECCCCCEEECCCCCEEE
VGVVPETSQTDPTGVGDAFRAGFLTGRSAGLGLERSAQLGSLVAVLVLESTGTQEWQWDY
EEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHEEEEEEEECCCCCCEEECH
EAAASRLAGAYGEHAAAEIVAVLA
HHHHHHHHHCCCCHHHHHHHHCCC
>Mature Secondary Structure 
TIAVTGSIATDHLMRFPGRFSEQLLPEHLHKVSLSFLVDDLVMHRGGVAGNMAFAIGVL
EEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEE
GGEVALVGAAGADFADYRDWLKARGVNCDHVLISETAHTARFTCTTDVDMAQIASFYPGA
CCCEEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEECCCCHHHHHHHCCCC
MSEARNIKLADVVSAIGKPELVIIGANDPEAMFLHTEECRKLGLAFAADPSQQLARLSGE
HHHHCCCCHHHHHHHCCCCCEEEEECCCCCEEEEEHHHHHHHCCEEECCCHHHHHHCCHH
EIRRLVNGAAYLFTNDYEWDLLLSKTGWSEADVMAQIDLRVTTLGPKGVDLVEPDGTTIH
HHHHHHCCEEEEEECCCCEEEEEECCCCCCCCEEEEEEEEEEEECCCCCEEECCCCCEEE
VGVVPETSQTDPTGVGDAFRAGFLTGRSAGLGLERSAQLGSLVAVLVLESTGTQEWQWDY
EEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHEEEEEEEECCCCCCEEECH
EAAASRLAGAYGEHAAAEIVAVLA
HHHHHHHHHCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972