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The map label for this gene is ctaC

Identifier: 121638081

GI number: 121638081

Start: 2442304

End: 2443395

Strand: Reverse

Name: ctaC

Synonym: BCG_2216c

Alternate gene names: 121638081

Gene position: 2443395-2442304 (Counterclockwise)

Preceding gene: 121638083

Following gene: 121638080

Centisome position: 55.86

GC content: 59.62

Gene sequence:

>1092_bases
GTGACACCTCGCGGGCCAGGTCGTTTGCAACGCTTGTCGCAGTGCAGGCCTCAGCGCGGCTCCGGAGGGCCTGCCCGTGG
TCTTCGACAGCTGGCGCTCGCAGCAATGCTGGGGGCATTGGCCGTCACCGTCAGTGGATGCAGCTGGTCGGAAGCCCTGG
GCATCGGTTGGCCGGAGGGCATTACCCCGGAGGCACACCTCAATCGAGAACTGTGGATCGGGGCGGTGATCGCCTCCCTG
GCGGTTGGGGTAATCGTGTGGGGTCTCATCTTCTGGTCCGCGGTATTTCACCGGAAGAAGAACACCGACACTGAGTTGCC
CCGCCAGTTCGGCTACAACATGCCGCTAGAGCTGGTTCTCACCGTCATACCGTTCCTCATCATCTCGGTGCTGTTTTATT
TCACCGTCGTGGTGCAGGAGAAGATGCTGCAGATAGCCAAGGATCCCGAGGTCGTGATTGATATCACGTCTTTCCAGTGG
AATTGGAAGTTTGGCTATCAAAGGGTGAACTTCAAAGACGGCACACTGACCTATGATGGTGCCGATCCGGAGCGCAAGCG
CGCCATGGTTTCCAAGCCAGAGGGCAAGGACAAGTACGGCGAAGAGCTGGTCGGGCCGGTGCGCGGGCTCAACACCGAGG
ACCGGACCTACCTGAATTTCGACAAGGTCGAGACGTTGGGCACCAGCACCGAAATTCCGGTGCTGGTGCTGCCGTCCGGC
AAGCGTATCGAATTCCAAATGGCCTCAGCCGATGTGATACACGCATTCTGGGTGCCGGAGTTCTTGTTCAAGCGTGACGT
GATGCCTAACCCGGTGGCAAACAACTCGGTCAACGTCTTCCAGATCGAAGAAATCACCAAGACCGGAGCATTCGTGGGCC
ACTGCGCCGAGATGTGTGGCACGTATCACTCGATGATGAACTTCGAGGTCCGCGTCGTGACCCCCAACGATTTCAAGGCC
TACCTGCAGCAACGCATCGACGGGAAGACAAACGCCGAGGCCCTGCGGGCGATCAACCAGCCGCCCCTTGCGGTGACCAC
CCACCCGTTTGATACTCGCCGCGGTGAATTGGCCCCGCAGCCCGTAGGTTAG

Upstream 100 bases:

>100_bases
TCTACGCTGCGTAGTATTCGATGTCTGAGTTAGCCGATGGTTCTCGCCGCAGCCGGTGCTATCCCAGTCGGCCCAGCTTG
TGATACAGGAGGCGCCAACA

Downstream 100 bases:

>100_bases
GACGCTCATGCATATCGAAGCCCGACTGTTTGAGTTTGTCGCCGCGTTCTTCGTGGTGACGGCGGTGCTGTACGGCGTGT
TGACCTCGATGTTCGCCACC

Product: putative transmembrane cytochrome C oxidase (subunit II) ctaC

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MTPRGPGRLQRLSQCRPQRGSGGPARGLRQLALAAMLGALAVTVSGCSWSEALGIGWPEGITPEAHLNRELWIGAVIASL
AVGVIVWGLIFWSAVFHRKKNTDTELPRQFGYNMPLELVLTVIPFLIISVLFYFTVVVQEKMLQIAKDPEVVIDITSFQW
NWKFGYQRVNFKDGTLTYDGADPERKRAMVSKPEGKDKYGEELVGPVRGLNTEDRTYLNFDKVETLGTSTEIPVLVLPSG
KRIEFQMASADVIHAFWVPEFLFKRDVMPNPVANNSVNVFQIEEITKTGAFVGHCAEMCGTYHSMMNFEVRVVTPNDFKA
YLQQRIDGKTNAEALRAINQPPLAVTTHPFDTRRGELAPQPVG

Sequences:

>Translated_363_residues
MTPRGPGRLQRLSQCRPQRGSGGPARGLRQLALAAMLGALAVTVSGCSWSEALGIGWPEGITPEAHLNRELWIGAVIASL
AVGVIVWGLIFWSAVFHRKKNTDTELPRQFGYNMPLELVLTVIPFLIISVLFYFTVVVQEKMLQIAKDPEVVIDITSFQW
NWKFGYQRVNFKDGTLTYDGADPERKRAMVSKPEGKDKYGEELVGPVRGLNTEDRTYLNFDKVETLGTSTEIPVLVLPSG
KRIEFQMASADVIHAFWVPEFLFKRDVMPNPVANNSVNVFQIEEITKTGAFVGHCAEMCGTYHSMMNFEVRVVTPNDFKA
YLQQRIDGKTNAEALRAINQPPLAVTTHPFDTRRGELAPQPVG
>Mature_362_residues
TPRGPGRLQRLSQCRPQRGSGGPARGLRQLALAAMLGALAVTVSGCSWSEALGIGWPEGITPEAHLNRELWIGAVIASLA
VGVIVWGLIFWSAVFHRKKNTDTELPRQFGYNMPLELVLTVIPFLIISVLFYFTVVVQEKMLQIAKDPEVVIDITSFQWN
WKFGYQRVNFKDGTLTYDGADPERKRAMVSKPEGKDKYGEELVGPVRGLNTEDRTYLNFDKVETLGTSTEIPVLVLPSGK
RIEFQMASADVIHAFWVPEFLFKRDVMPNPVANNSVNVFQIEEITKTGAFVGHCAEMCGTYHSMMNFEVRVVTPNDFKAY
LQQRIDGKTNAEALRAINQPPLAVTTHPFDTRRGELAPQPVG

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COX2_MYCBO (P63855)

Other databases:

- EMBL:   BX248341
- RefSeq:   NP_855872.1
- ProteinModelPortal:   P63855
- EnsemblBacteria:   EBMYCT00000016476
- GeneID:   1091345
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2223c
- GeneTree:   EBGT00050000016956
- HOGENOM:   HBG428789
- OMA:   YQWNWKF
- ProtClustDB:   CLSK791696
- BioCyc:   MBOV233413:MB2223C-MONOMER
- BRENDA:   1.9.3.1
- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759
- Gene3D:   G3DSA:1.10.287.90
- Gene3D:   G3DSA:2.60.40.420
- PANTHER:   PTHR22888

Pfam domain/function: PF00116 COX2; SSF49503 Cupredoxin; SSF81464 Cyt_c_oxidase_II-like_TM

EC number: =1.9.3.1

Molecular weight: Translated: 40480; Mature: 40349

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: PS00078 COX2; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x170cf610)-; HASH(0x166bb8dc)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPRGPGRLQRLSQCRPQRGSGGPARGLRQLALAAMLGALAVTVSGCSWSEALGIGWPEG
CCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCC
ITPEAHLNRELWIGAVIASLAVGVIVWGLIFWSAVFHRKKNTDTELPRQFGYNMPLELVL
CCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCHHHHH
TVIPFLIISVLFYFTVVVQEKMLQIAKDPEVVIDITSFQWNWKFGYQRVNFKDGTLTYDG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEECCEEEEECCCEEEECC
ADPERKRAMVSKPEGKDKYGEELVGPVRGLNTEDRTYLNFDKVETLGTSTEIPVLVLPSG
CCHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEECHHHHHHCCCCCCCCEEEECCC
KRIEFQMASADVIHAFWVPEFLFKRDVMPNPVANNSVNVFQIEEITKTGAFVGHCAEMCG
CEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
TYHSMMNFEVRVVTPNDFKAYLQQRIDGKTNAEALRAINQPPLAVTTHPFDTRRGELAPQ
HHHHHHCEEEEEECCCHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCC
PVG
CCH
>Mature Secondary Structure 
TPRGPGRLQRLSQCRPQRGSGGPARGLRQLALAAMLGALAVTVSGCSWSEALGIGWPEG
CCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCC
ITPEAHLNRELWIGAVIASLAVGVIVWGLIFWSAVFHRKKNTDTELPRQFGYNMPLELVL
CCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCHHHHH
TVIPFLIISVLFYFTVVVQEKMLQIAKDPEVVIDITSFQWNWKFGYQRVNFKDGTLTYDG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEECCEEEEECCCEEEECC
ADPERKRAMVSKPEGKDKYGEELVGPVRGLNTEDRTYLNFDKVETLGTSTEIPVLVLPSG
CCHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEECHHHHHHCCCCCCCCEEEECCC
KRIEFQMASADVIHAFWVPEFLFKRDVMPNPVANNSVNVFQIEEITKTGAFVGHCAEMCG
CEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
TYHSMMNFEVRVVTPNDFKAYLQQRIDGKTNAEALRAINQPPLAVTTHPFDTRRGELAPQ
HHHHHHCEEEEEECCCHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCC
PVG
CCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972