| Definition | Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome. |
|---|---|
| Accession | NC_008769 |
| Length | 4,374,522 |
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The map label for this gene is idsA2 [H]
Identifier: 121638053
GI number: 121638053
Start: 2413377
End: 2414435
Strand: Direct
Name: idsA2 [H]
Synonym: BCG_2188
Alternate gene names: 121638053
Gene position: 2413377-2414435 (Clockwise)
Preceding gene: 121638051
Following gene: 121638054
Centisome position: 55.17
GC content: 67.61
Gene sequence:
>1059_bases TTGGCCGGCGCCATCACCGACCAGCTGCGGAGGTATTTGCACGGCCGCCGCCGTGCGGCCGCCCACATGGGCAGTGACTA CGACGGCCTGATCGCCGACCTGGAGGATTTCGTTCTCGGCGGGGGCAAGCGCCTACGACCGCTCTTCGCCTATTGGGGCT GGCACGCCGTTGCCAGTCGGGAACCCGATCCTGATGTGCTGCTGCTGTTTTCCGCGCTGGAACTGCTGCACGCCTGGGCG CTGGTCCACGACGACCTGATCGACCGTTCCGCCACCCGCCGGGGCCGCCCGACCGCCCAGCTGCGCTACGCGGCGCTGCA CCGCGATCGGGACTGGCGGGGGTCACCGGACCAGTTCGGCATGTCGGCGGCCATCCTGCTCGGCGACCTCGCACAGGTCT GGGCTGACGACATCGTCTCGAAGGTCTGCCAGTCCGCCCTGGCACCCGATGCCCAGCGGCGAGTGCATCGGGTGTGGGCC GATATCCGCAACGAGGTGCTGGGCGGGCAATACCTCGACATCGTCGCAGAGGCCAGTGCCGCCGAGTCGATCGAGTCGGC GATGAACGTCGCGACGCTCAAGACCGCCTGCTACACGGTATCGCGACCGCTACAGCTTGGGACGGCCGCCGCGGCCGACA GATCCGACGTAGCGGCCATCTTCGAGCATTTCGGAGCGGACCTCGGCGTAGCGTTTCAGTTGCGCGACGACGTGCTTGGC GTGTTTGGCGACCCAGCCGTGACGGGCAAGCCGTCCGGTGACGACCTAAAGTCGGGCAAGCGTACCGTGCTGGTAGCCGA AGCGGTGGAATTGGCGGACAGGTCAGACCCCTTGGCGGCCAAACTATTACGGACCTCGATTGGCACCCGATTGACTGATG CGCAGGTACGTGAACTGCGCACGGTCATCGAGGCAGTGGGCGCGCGCGCCGCCGCGGAGAGCCGCATCGCCGCGCTCACC CAGCGAGCACTGGCCACCCTGGCGTCCGCACCCATCAACGCAACAGCCAAGGCCGGGCTGTCCGAACTGGCCATGATGGC TGCGAACCGGTCCGCCTAA
Upstream 100 bases:
>100_bases CGCGCCGGCGCGGAATACACTGTCGGGCCATAGGCACGCCAAATGAGAAAGGGGCGCCGCGCTGAGCCTGAATGCACCGG CAGCACCGGCAGCGGTCCAG
Downstream 100 bases:
>100_bases CCGATGACTACTCCGAGCCATGCTCCAGCGGTTGATTTGGCTACAGCGAAAGATGCTGTTGTCCAACACCTTTCGCGACT TTTCGAGTTCACTACCGGTC
Product: putative geranylgeranyl pyrophosphate synthetase idsA2
Products: NA
Alternate protein names: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl pyrophosphate synthase; FPP synthase; Geranyltranstransferase [H]
Number of amino acids: Translated: 352; Mature: 351
Protein sequence:
>352_residues MAGAITDQLRRYLHGRRRAAAHMGSDYDGLIADLEDFVLGGGKRLRPLFAYWGWHAVASREPDPDVLLLFSALELLHAWA LVHDDLIDRSATRRGRPTAQLRYAALHRDRDWRGSPDQFGMSAAILLGDLAQVWADDIVSKVCQSALAPDAQRRVHRVWA DIRNEVLGGQYLDIVAEASAAESIESAMNVATLKTACYTVSRPLQLGTAAAADRSDVAAIFEHFGADLGVAFQLRDDVLG VFGDPAVTGKPSGDDLKSGKRTVLVAEAVELADRSDPLAAKLLRTSIGTRLTDAQVRELRTVIEAVGARAAAESRIAALT QRALATLASAPINATAKAGLSELAMMAANRSA
Sequences:
>Translated_352_residues MAGAITDQLRRYLHGRRRAAAHMGSDYDGLIADLEDFVLGGGKRLRPLFAYWGWHAVASREPDPDVLLLFSALELLHAWA LVHDDLIDRSATRRGRPTAQLRYAALHRDRDWRGSPDQFGMSAAILLGDLAQVWADDIVSKVCQSALAPDAQRRVHRVWA DIRNEVLGGQYLDIVAEASAAESIESAMNVATLKTACYTVSRPLQLGTAAAADRSDVAAIFEHFGADLGVAFQLRDDVLG VFGDPAVTGKPSGDDLKSGKRTVLVAEAVELADRSDPLAAKLLRTSIGTRLTDAQVRELRTVIEAVGARAAAESRIAALT QRALATLASAPINATAKAGLSELAMMAANRSA >Mature_351_residues AGAITDQLRRYLHGRRRAAAHMGSDYDGLIADLEDFVLGGGKRLRPLFAYWGWHAVASREPDPDVLLLFSALELLHAWAL VHDDLIDRSATRRGRPTAQLRYAALHRDRDWRGSPDQFGMSAAILLGDLAQVWADDIVSKVCQSALAPDAQRRVHRVWAD IRNEVLGGQYLDIVAEASAAESIESAMNVATLKTACYTVSRPLQLGTAAAADRSDVAAIFEHFGADLGVAFQLRDDVLGV FGDPAVTGKPSGDDLKSGKRTVLVAEAVELADRSDPLAAKLLRTSIGTRLTDAQVRELRTVIEAVGARAAAESRIAALTQ RALATLASAPINATAKAGLSELAMMAANRSA
Specific function: Supplies Octaprenyl Diphosphate, The Precursor For The Side Chain Of The Isoprenoid Quinones Ubiquinone And Menaquinone. [C]
COG id: COG0142
COG function: function code H; Geranylgeranyl pyrophosphate synthase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the FPP/GGPP synthase family [H]
Homologues:
Organism=Escherichia coli, GI1789578, Length=302, Percent_Identity=28.8079470198675, Blast_Score=81, Evalue=8e-17, Organism=Escherichia coli, GI1786623, Length=238, Percent_Identity=31.0924369747899, Blast_Score=71, Evalue=1e-13, Organism=Drosophila melanogaster, GI24651612, Length=250, Percent_Identity=26, Blast_Score=70, Evalue=3e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000092 - InterPro: IPR017446 - InterPro: IPR008949 [H]
Pfam domain/function: PF00348 polyprenyl_synt [H]
EC number: =2.5.1.1; =2.5.1.10 [H]
Molecular weight: Translated: 37781; Mature: 37650
Theoretical pI: Translated: 6.73; Mature: 6.73
Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 1.7 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAGAITDQLRRYLHGRRRAAAHMGSDYDGLIADLEDFVLGGGKRLRPLFAYWGWHAVASR CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC EPDPDVLLLFSALELLHAWALVHDDLIDRSATRRGRPTAQLRYAALHRDRDWRGSPDQFG CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHH MSAAILLGDLAQVWADDIVSKVCQSALAPDAQRRVHRVWADIRNEVLGGQYLDIVAEASA HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH AESIESAMNVATLKTACYTVSRPLQLGTAAAADRSDVAAIFEHFGADLGVAFQLRDDVLG HHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHCCHHHHHHHHHHHCCCCEEEEEEHHHHHH VFGDPAVTGKPSGDDLKSGKRTVLVAEAVELADRSDPLAAKLLRTSIGTRLTDAQVRELR HCCCCCCCCCCCCCHHHCCCCEEEHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHH TVIEAVGARAAAESRIAALTQRALATLASAPINATAKAGLSELAMMAANRSA HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC >Mature Secondary Structure AGAITDQLRRYLHGRRRAAAHMGSDYDGLIADLEDFVLGGGKRLRPLFAYWGWHAVASR CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC EPDPDVLLLFSALELLHAWALVHDDLIDRSATRRGRPTAQLRYAALHRDRDWRGSPDQFG CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHH MSAAILLGDLAQVWADDIVSKVCQSALAPDAQRRVHRVWADIRNEVLGGQYLDIVAEASA HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH AESIESAMNVATLKTACYTVSRPLQLGTAAAADRSDVAAIFEHFGADLGVAFQLRDDVLG HHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHCCHHHHHHHHHHHCCCCEEEEEEHHHHHH VFGDPAVTGKPSGDDLKSGKRTVLVAEAVELADRSDPLAAKLLRTSIGTRLTDAQVRELR HCCCCCCCCCCCCCHHHCCCCEEEHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHH TVIEAVGARAAAESRIAALTQRALATLASAPINATAKAGLSELAMMAANRSA HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8688087 [H]