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The map label for this gene is ftsW [C]

Identifier: 121638036

GI number: 121638036

Start: 2393358

End: 2394932

Strand: Reverse

Name: ftsW [C]

Synonym: BCG_2171c

Alternate gene names: 121638036

Gene position: 2394932-2393358 (Counterclockwise)

Preceding gene: 121638037

Following gene: 121638035

Centisome position: 54.75

GC content: 67.49

Gene sequence:

>1575_bases
GTGCTAACCCGGTTGCTGCGTCGGGGCACCAGCGACACCGACGGCTCCCAGACTCGAGGGGCCGAGCCGGTCGAGGGGCA
GCGGACGGGCCCGGAAGAAGCCTCTAACCCGGGTTCGGCGAGGCCCCGCACCCGTTTCGGTGCCTGGCTGGGCCGTCCGA
TGACCTCGTTTCACCTCATCATCGCCGTTGCCGCATTGCTGACCACCCTTGGACTGATCATGGTGCTGTCGGCATCGGCG
GTGCGGTCCTACGACGACGACGGATCGGCTTGGGTGATCTTCGGCAAGCAGGTCTTGTGGACGCTTGTGGGTCTTATCGG
CGGCTATGTCTGTCTGCGGATGTCGGTGCGGTTCATGCGGCGCATCGCCTTCTCCGGTTTCGCGATCACCATCGTGATGC
TGGTGCTGGTGCTGGTGCCGGGGATCGGCAAGGAGGCCAACGGCTCGCGCGGCTGGTTCGTGGTCGCGGGCTTCTCGATG
CAGCCCTCTGAGCTGGCTAAGATGGCGTTCGCCATCTGGGGAGCGCATCTGCTGGCCGCCCGGCGCATGGAACGGGCTTC
ACTGCGCGAGATGCTGATTCCACTGGTGCCGGCCGCCGTCGTTGCGCTGGCGCTGATCGTGGCCCAGCCCGACCTCGGAC
AGACCGTGTCGATGGGCATCATCTTGTTGGGCCTGCTGTGGTATGCGGGGCTGCCGCTGCGCGTCTTCCTCAGCTCACTG
GCGGCGGTCGTCGTCTCGGCCGCCATCCTGGCGGTGTCCGCGGGCTACCGATCCGACCGGGTGCGGTCGTGGCTCAACCC
CGAAAACGATCCGCAAGACTCCGGCTACCAGGCCCGACAGGCAAAGTTCGCGCTGGCTCAAGGTGGCATTTTCGGCGACG
GTCTGGGCCAAGGCGTGGCCAAGTGGAACTACTTGCCCAACGCCCACAACGACTTCATTTTCGCCATCATCGGCGAAGAG
CTGGGTCTCGTCGGCGCGCTCGGACTGCTGGGGCTATTCGGATTGTTCGCCTACACCGGCATGCGCATCGCTAGCCGGTC
CGCCGACCCGTTCCTGCGGCTGCTGACCGCCACCACGACACTGTGGGTGCTGGGACAGGCGTTCATCAACATCGGCTATG
TGATCGGGCTGCTGCCCGTCACCGGCCTGCAGCTGCCGCTCATCTCCGCCGGTGGAACCTCCACGGCCGCAACACTTTCG
CTGATAGGCATCATCGCCAACGCGGCTCGCCACGAACCGGAGGCGGTGGCCGCGCTGCGGGCTGGGCGCGACGACAAGGT
GAACCGGTTGCTGCGGCTGCCGCTGCCCGAGCCGTATCTGCCCCCTCGTCTCGAGGCGTTTCGTGACCGCAAGCGCGCCA
ACCCGCAACCGGCCCAAACGCAGCCCGCGCGGAAGACCCCCCGCACGGCGCCCGGACAGCCTGCCCGGCAGATGGGCCTG
CCCCCGCGACCCGGCTCGCCCCGCACGGCCGATCCGCCGGTTCGTCGATCAGTGCATCATGGAGCTGGCCAGCGGTACGC
GGGCCAGCGTCGCACACGGCGCGTTCGGGCATTGGAAGGTCAGCGTTACGGGTGA

Upstream 100 bases:

>100_bases
CACCGGCCGGCGCCTCATTCGACCAGTTCACCGGTTATGCCGACCGGGGCGAGGCATTCGCGACCGCGGTCCGCGCGGTG
ATCCGGTAGGCGGGGGCAGC

Downstream 100 bases:

>100_bases
AGGACACGGTCAGCCAGCCGGCCGGCGGGCGCGGGGCAACGGCGCCCCGGCCCGCCGATGCCGCCTCGCCGTCTTGTGGT
TCCTCGCCGTCTGCTGATTC

Product: FtsW-like protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MLTRLLRRGTSDTDGSQTRGAEPVEGQRTGPEEASNPGSARPRTRFGAWLGRPMTSFHLIIAVAALLTTLGLIMVLSASA
VRSYDDDGSAWVIFGKQVLWTLVGLIGGYVCLRMSVRFMRRIAFSGFAITIVMLVLVLVPGIGKEANGSRGWFVVAGFSM
QPSELAKMAFAIWGAHLLAARRMERASLREMLIPLVPAAVVALALIVAQPDLGQTVSMGIILLGLLWYAGLPLRVFLSSL
AAVVVSAAILAVSAGYRSDRVRSWLNPENDPQDSGYQARQAKFALAQGGIFGDGLGQGVAKWNYLPNAHNDFIFAIIGEE
LGLVGALGLLGLFGLFAYTGMRIASRSADPFLRLLTATTTLWVLGQAFINIGYVIGLLPVTGLQLPLISAGGTSTAATLS
LIGIIANAARHEPEAVAALRAGRDDKVNRLLRLPLPEPYLPPRLEAFRDRKRANPQPAQTQPARKTPRTAPGQPARQMGL
PPRPGSPRTADPPVRRSVHHGAGQRYAGQRRTRRVRALEGQRYG

Sequences:

>Translated_524_residues
MLTRLLRRGTSDTDGSQTRGAEPVEGQRTGPEEASNPGSARPRTRFGAWLGRPMTSFHLIIAVAALLTTLGLIMVLSASA
VRSYDDDGSAWVIFGKQVLWTLVGLIGGYVCLRMSVRFMRRIAFSGFAITIVMLVLVLVPGIGKEANGSRGWFVVAGFSM
QPSELAKMAFAIWGAHLLAARRMERASLREMLIPLVPAAVVALALIVAQPDLGQTVSMGIILLGLLWYAGLPLRVFLSSL
AAVVVSAAILAVSAGYRSDRVRSWLNPENDPQDSGYQARQAKFALAQGGIFGDGLGQGVAKWNYLPNAHNDFIFAIIGEE
LGLVGALGLLGLFGLFAYTGMRIASRSADPFLRLLTATTTLWVLGQAFINIGYVIGLLPVTGLQLPLISAGGTSTAATLS
LIGIIANAARHEPEAVAALRAGRDDKVNRLLRLPLPEPYLPPRLEAFRDRKRANPQPAQTQPARKTPRTAPGQPARQMGL
PPRPGSPRTADPPVRRSVHHGAGQRYAGQRRTRRVRALEGQRYG
>Mature_524_residues
MLTRLLRRGTSDTDGSQTRGAEPVEGQRTGPEEASNPGSARPRTRFGAWLGRPMTSFHLIIAVAALLTTLGLIMVLSASA
VRSYDDDGSAWVIFGKQVLWTLVGLIGGYVCLRMSVRFMRRIAFSGFAITIVMLVLVLVPGIGKEANGSRGWFVVAGFSM
QPSELAKMAFAIWGAHLLAARRMERASLREMLIPLVPAAVVALALIVAQPDLGQTVSMGIILLGLLWYAGLPLRVFLSSL
AAVVVSAAILAVSAGYRSDRVRSWLNPENDPQDSGYQARQAKFALAQGGIFGDGLGQGVAKWNYLPNAHNDFIFAIIGEE
LGLVGALGLLGLFGLFAYTGMRIASRSADPFLRLLTATTTLWVLGQAFINIGYVIGLLPVTGLQLPLISAGGTSTAATLS
LIGIIANAARHEPEAVAALRAGRDDKVNRLLRLPLPEPYLPPRLEAFRDRKRANPQPAQTQPARKTPRTAPGQPARQMGL
PPRPGSPRTADPPVRRSVHHGAGQRYAGQRRTRRVRALEGQRYG

Specific function: This Is A Septum-Peptidoglycan Biosynthetic Protein, Involved In Cell Wall Formation. Plays A Role In The Stabilization Of The Ftsz Ring During Cell Division. [C]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family

Homologues:

Organism=Escherichia coli, GI1786277, Length=332, Percent_Identity=34.3373493975904, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI1786853, Length=294, Percent_Identity=36.0544217687075, Blast_Score=128, Evalue=9e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTWH_MYCBO (P63763)

Other databases:

- EMBL:   BX248341
- RefSeq:   NP_855827.1
- EnsemblBacteria:   EBMYCT00000015297
- GeneID:   1091253
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2178c
- GeneTree:   EBGT00050000015955
- HOGENOM:   HBG729614
- OMA:   GAWLSRP
- ProtClustDB:   CLSK791662
- BioCyc:   MBOV233413:MB2178C-MONOMER
- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437
- TIGRFAMs:   TIGR02614

Pfam domain/function: PF01098 FTSW_RODA_SPOVE

EC number: NA

Molecular weight: Translated: 56338; Mature: 56338

Theoretical pI: Translated: 11.66; Mature: 11.66

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12a157c0)-; HASH(0x16fcfd98)-; HASH(0x16fbf11c)-; HASH(0x15fd46f0)-; HASH(0x169d76a4)-; HASH(0x16ab5c5c)-; HASH(0x15a8de08)-; HASH(0x15d9ba7c)-; HASH(0x12a80874)-; HASH(0x146a1ec4)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTRLLRRGTSDTDGSQTRGAEPVEGQRTGPEEASNPGSARPRTRFGAWLGRPMTSFHLI
CHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHH
IAVAALLTTLGLIMVLSASAVRSYDDDGSAWVIFGKQVLWTLVGLIGGYVCLRMSVRFMR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
RIAFSGFAITIVMLVLVLVPGIGKEANGSRGWFVVAGFSMQPSELAKMAFAIWGAHLLAA
HHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
RRMERASLREMLIPLVPAAVVALALIVAQPDLGQTVSMGIILLGLLWYAGLPLRVFLSSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
AAVVVSAAILAVSAGYRSDRVRSWLNPENDPQDSGYQARQAKFALAQGGIFGDGLGQGVA
HHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHH
KWNYLPNAHNDFIFAIIGEELGLVGALGLLGLFGLFAYTGMRIASRSADPFLRLLTATTT
HCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LWVLGQAFINIGYVIGLLPVTGLQLPLISAGGTSTAATLSLIGIIANAARHEPEAVAALR
HHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
AGRDDKVNRLLRLPLPEPYLPPRLEAFRDRKRANPQPAQTQPARKTPRTAPGQPARQMGL
CCCCHHHHHHEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCC
PPRPGSPRTADPPVRRSVHHGAGQRYAGQRRTRRVRALEGQRYG
CCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCH
>Mature Secondary Structure
MLTRLLRRGTSDTDGSQTRGAEPVEGQRTGPEEASNPGSARPRTRFGAWLGRPMTSFHLI
CHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHH
IAVAALLTTLGLIMVLSASAVRSYDDDGSAWVIFGKQVLWTLVGLIGGYVCLRMSVRFMR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
RIAFSGFAITIVMLVLVLVPGIGKEANGSRGWFVVAGFSMQPSELAKMAFAIWGAHLLAA
HHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
RRMERASLREMLIPLVPAAVVALALIVAQPDLGQTVSMGIILLGLLWYAGLPLRVFLSSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
AAVVVSAAILAVSAGYRSDRVRSWLNPENDPQDSGYQARQAKFALAQGGIFGDGLGQGVA
HHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHH
KWNYLPNAHNDFIFAIIGEELGLVGALGLLGLFGLFAYTGMRIASRSADPFLRLLTATTT
HCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LWVLGQAFINIGYVIGLLPVTGLQLPLISAGGTSTAATLSLIGIIANAARHEPEAVAALR
HHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
AGRDDKVNRLLRLPLPEPYLPPRLEAFRDRKRANPQPAQTQPARKTPRTAPGQPARQMGL
CCCCHHHHHHEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCC
PPRPGSPRTADPPVRRSVHHGAGQRYAGQRRTRRVRALEGQRYG
CCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972