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The map label for this gene is yfiH [C]

Identifier: 121638031

GI number: 121638031

Start: 2387632

End: 2388384

Strand: Reverse

Name: yfiH [C]

Synonym: BCG_2166c

Alternate gene names: 121638031

Gene position: 2388384-2387632 (Counterclockwise)

Preceding gene: 121638032

Following gene: 121638030

Centisome position: 54.6

GC content: 68.53

Gene sequence:

>753_bases
TTGCTCGCCAGTACGCGGCACATCGCCCGCGGCGATACTGGGAACGTGAGTGTTCGCATCCGTCGGGTCACCACCACCCG
GGCAGGTGGTGTGTCGGCCCCACCGTTCGACACCTTCAACCTCGGCGACCACGTTGGTGACGACCCGGCCGCGGTGGCGG
CAAACCGCGCTCGGCTGGCCGCAGCCATCGGACTGCCCGGCAACCGAGTGGTGTGGATGAACCAGGTGCACGGGGATCGG
GTCGAGCTGGTCGACCAGCCGCGCAATACGGCACTCGATGACACCGACGGATTGGTGACCGCTACACCCCGATTGGCGCT
GGCGGTTGTGACCGCCGACTGCGTGCCGGTGCTGATGGCCGACGCACGGGCCGGTATCGCCGCCGCGGTTCATGCCGGTC
GGGCAGGCGCGCAGCGCGGTGTGGTGGTTCGCGCGCTGGAGGTGATGTTGAGCCTGGGTGCCCAGGTCCGCGACATCTCG
GCACTGTTGGGTCCCGCGGTCAGTGGTCGCAACTACGAAGTGCCCGCAGCGATGGCCGATGAGGTCGAGGCGGCGTTGCC
GGGCAGCCGCACCACCACCGCTGCCGGCACTCCCGGAGTCGACCTGCGCGCCGGAATCGCTTGCCAGCTCCGCGATTTGG
GTGTTGAGTCTATCGACGTCGATCCCCGCTGCACGGTGGCCGATCCGACGTTGTTCAGCCACCGCCGCGATGCGCCCACC
GGACGGTTCGCGTCGTTGGTGTGGATGGAATGA

Upstream 100 bases:

>100_bases
GTCAGCGTGCCGTTGCACACCAACGGCGCAACCCTGAGCATCGGCGGTGATGACGACGATGTCGACGTGCCGCCCTTCAT
GCGCCGCTGAGAGCATCGGC

Downstream 100 bases:

>100_bases
CCGCGATGGCGGCGGATCTTTCGGCGTATCCAGACCGCGAATCGGAATTGACGCATGCGTTGGCGGCAATGCGATCGCGA
CTTGCGGCGGCCGCGGAGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MLASTRHIARGDTGNVSVRIRRVTTTRAGGVSAPPFDTFNLGDHVGDDPAAVAANRARLAAAIGLPGNRVVWMNQVHGDR
VELVDQPRNTALDDTDGLVTATPRLALAVVTADCVPVLMADARAGIAAAVHAGRAGAQRGVVVRALEVMLSLGAQVRDIS
ALLGPAVSGRNYEVPAAMADEVEAALPGSRTTTAAGTPGVDLRAGIACQLRDLGVESIDVDPRCTVADPTLFSHRRDAPT
GRFASLVWME

Sequences:

>Translated_250_residues
MLASTRHIARGDTGNVSVRIRRVTTTRAGGVSAPPFDTFNLGDHVGDDPAAVAANRARLAAAIGLPGNRVVWMNQVHGDR
VELVDQPRNTALDDTDGLVTATPRLALAVVTADCVPVLMADARAGIAAAVHAGRAGAQRGVVVRALEVMLSLGAQVRDIS
ALLGPAVSGRNYEVPAAMADEVEAALPGSRTTTAAGTPGVDLRAGIACQLRDLGVESIDVDPRCTVADPTLFSHRRDAPT
GRFASLVWME
>Mature_250_residues
MLASTRHIARGDTGNVSVRIRRVTTTRAGGVSAPPFDTFNLGDHVGDDPAAVAANRARLAAAIGLPGNRVVWMNQVHGDR
VELVDQPRNTALDDTDGLVTATPRLALAVVTADCVPVLMADARAGIAAAVHAGRAGAQRGVVVRALEVMLSLGAQVRDIS
ALLGPAVSGRNYEVPAAMADEVEAALPGSRTTTAAGTPGVDLRAGIACQLRDLGVESIDVDPRCTVADPTLFSHRRDAPT
GRFASLVWME

Specific function: Unknown

COG id: COG1496

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0124 family

Homologues:

Organism=Homo sapiens, GI190194374, Length=224, Percent_Identity=25.4464285714286, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI190194372, Length=224, Percent_Identity=25.4464285714286, Blast_Score=68, Evalue=6e-12,
Organism=Escherichia coli, GI1788945, Length=234, Percent_Identity=39.3162393162393, Blast_Score=131, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2149_MYCTU (P67256)

Other databases:

- EMBL:   BX842578
- EMBL:   AE000516
- PIR:   A70579
- RefSeq:   NP_216665.1
- RefSeq:   NP_336678.1
- ProteinModelPortal:   P67256
- SMR:   P67256
- EnsemblBacteria:   EBMYCT00000003942
- EnsemblBacteria:   EBMYCT00000072632
- GeneID:   888121
- GeneID:   924253
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2208
- KEGG:   mtu:Rv2149c
- TIGR:   MT2208
- TubercuList:   Rv2149c
- GeneTree:   EBGT00050000017585
- HOGENOM:   HBG751647
- OMA:   PRCTIED
- ProtClustDB:   CLSK791660
- InterPro:   IPR003730
- InterPro:   IPR011324
- Gene3D:   G3DSA:3.60.140.10
- TIGRFAMs:   TIGR00726

Pfam domain/function: PF02578 Cu-oxidase_4; SSF64438 Cytotoxic_necrot_fac-like_cat

EC number: NA

Molecular weight: Translated: 25965; Mature: 25965

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLASTRHIARGDTGNVSVRIRRVTTTRAGGVSAPPFDTFNLGDHVGDDPAAVAANRARLA
CCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEE
AAIGLPGNRVVWMNQVHGDRVELVDQPRNTALDDTDGLVTATPRLALAVVTADCVPVLMA
EEECCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCEEEECCCEEEEEEHHHHHHHHHH
DARAGIAAAVHAGRAGAQRGVVVRALEVMLSLGAQVRDISALLGPAVSGRNYEVPAAMAD
HCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEECCHHHHH
EVEAALPGSRTTTAAGTPGVDLRAGIACQLRDLGVESIDVDPRCTVADPTLFSHRRDAPT
HHHHHCCCCCCCCCCCCCCCCCCCCCEEEHHHCCCCEECCCCCCEECCCHHHHCCCCCCC
GRFASLVWME
CCEEEEEECC
>Mature Secondary Structure
MLASTRHIARGDTGNVSVRIRRVTTTRAGGVSAPPFDTFNLGDHVGDDPAAVAANRARLA
CCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEE
AAIGLPGNRVVWMNQVHGDRVELVDQPRNTALDDTDGLVTATPRLALAVVTADCVPVLMA
EEECCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCEEEECCCEEEEEEHHHHHHHHHH
DARAGIAAAVHAGRAGAQRGVVVRALEVMLSLGAQVRDISALLGPAVSGRNYEVPAAMAD
HCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEECCHHHHH
EVEAALPGSRTTTAAGTPGVDLRAGIACQLRDLGVESIDVDPRCTVADPTLFSHRRDAPT
HHHHHCCCCCCCCCCCCCCCCCCCCCEEEHHHCCCCEECCCCCCEECCCHHHHCCCCCCC
GRFASLVWME
CCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036