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The map label for this gene is yggS [C]

Identifier: 121638030

GI number: 121638030

Start: 2386850

End: 2387626

Strand: Reverse

Name: yggS [C]

Synonym: BCG_2165c

Alternate gene names: 121638030

Gene position: 2387626-2386850 (Counterclockwise)

Preceding gene: 121638031

Following gene: 121638029

Centisome position: 54.58

GC content: 63.58

Gene sequence:

>777_bases
ATGGCGGCGGATCTTTCGGCGTATCCAGACCGCGAATCGGAATTGACGCATGCGTTGGCGGCAATGCGATCGCGACTTGC
GGCGGCCGCGGAGGCGGCGGGTCGCAATGTCGGCGAAATTGAACTTCTACCGATTACCAAATTCTTTCCAGCAACCGATG
TTGCGATTTTGTTTCGATTGGGTTGTCGGTCCGTTGGCGAATCGCGCGAACAGGAAGCTTCAGCCAAGATGGCCGAACTT
AATCGGTTGTTGGCGGCTGCCGAGTTGGGTCACTCGGGGGGTGTGCACTGGCACATGGTGGGCCGGATTCAACGCAACAA
AGCCGGGTCGCTGGCTCGCTGGGCGCACACCGCTCACTCGGTGGACAGCTCGCGGTTGGTGACCGCGCTGGATCGGGCGG
TTGTTGCGGCGCTGGCCGAACACCGTCGTGGCGAGCGGCTGCGGGTTTACGTCCAGGTCAGCCTCGACGGTGACGGATCC
CGGGGCGGCGTCGACAGCACGACGCCCGGCGCCGTAGACCGGATTTGCGCGCAGGTGCAGGAGTCAGAGGGCCTCGAACT
GGTCGGGTTGATGGGCATTCCGCCGCTGGATTGGGACCCGGACGAGGCCTTTGACCGGCTGCAATCGGAGCACAACCGGG
TGCGTGCGATGTTCCCGCACGCGATCGGTCTGTCGGCGGGCATGTCCAACGACCTTGAAGTCGCCGTCAAACATGGTTCG
ACCTGTGTGCGTGTCGGTACCGCGCTATTGGGTCCGCGGCGGTTACGGTCACCGTGA

Upstream 100 bases:

>100_bases
TCGATCCCCGCTGCACGGTGGCCGATCCGACGTTGTTCAGCCACCGCCGCGATGCGCCCACCGGACGGTTCGCGTCGTTG
GTGTGGATGGAATGACCGCG

Downstream 100 bases:

>100_bases
ATAGTCACTGTAGTCACACCTTCATCACAGACAACAGATCTCCCAGGGCTAGAAGGGGTCACGCAATGAGCACACTGCAC
AAGGTCAAGGCCTACTTCGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MAADLSAYPDRESELTHALAAMRSRLAAAAEAAGRNVGEIELLPITKFFPATDVAILFRLGCRSVGESREQEASAKMAEL
NRLLAAAELGHSGGVHWHMVGRIQRNKAGSLARWAHTAHSVDSSRLVTALDRAVVAALAEHRRGERLRVYVQVSLDGDGS
RGGVDSTTPGAVDRICAQVQESEGLELVGLMGIPPLDWDPDEAFDRLQSEHNRVRAMFPHAIGLSAGMSNDLEVAVKHGS
TCVRVGTALLGPRRLRSP

Sequences:

>Translated_258_residues
MAADLSAYPDRESELTHALAAMRSRLAAAAEAAGRNVGEIELLPITKFFPATDVAILFRLGCRSVGESREQEASAKMAEL
NRLLAAAELGHSGGVHWHMVGRIQRNKAGSLARWAHTAHSVDSSRLVTALDRAVVAALAEHRRGERLRVYVQVSLDGDGS
RGGVDSTTPGAVDRICAQVQESEGLELVGLMGIPPLDWDPDEAFDRLQSEHNRVRAMFPHAIGLSAGMSNDLEVAVKHGS
TCVRVGTALLGPRRLRSP
>Mature_257_residues
AADLSAYPDRESELTHALAAMRSRLAAAAEAAGRNVGEIELLPITKFFPATDVAILFRLGCRSVGESREQEASAKMAELN
RLLAAAELGHSGGVHWHMVGRIQRNKAGSLARWAHTAHSVDSSRLVTALDRAVVAALAEHRRGERLRVYVQVSLDGDGSR
GGVDSTTPGAVDRICAQVQESEGLELVGLMGIPPLDWDPDEAFDRLQSEHNRVRAMFPHAIGLSAGMSNDLEVAVKHGST
CVRVGTALLGPRRLRSP

Specific function: Unknown

COG id: COG0325

COG function: function code R; Predicted enzyme with a TIM-barrel fold

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0001 family

Homologues:

Organism=Homo sapiens, GI6005842, Length=250, Percent_Identity=30, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1789321, Length=244, Percent_Identity=32.3770491803279, Blast_Score=114, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6319435, Length=264, Percent_Identity=25, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI45550861, Length=222, Percent_Identity=28.3783783783784, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2148_MYCTU (P67083)

Other databases:

- EMBL:   BX842578
- EMBL:   AE000516
- PIR:   H70578
- RefSeq:   NP_216664.1
- RefSeq:   NP_336677.1
- ProteinModelPortal:   P67083
- SMR:   P67083
- EnsemblBacteria:   EBMYCT00000002031
- EnsemblBacteria:   EBMYCT00000071282
- GeneID:   888127
- GeneID:   924254
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2207
- KEGG:   mtu:Rv2148c
- TIGR:   MT2207
- TubercuList:   Rv2148c
- GeneTree:   EBGT00050000017450
- HOGENOM:   HBG289671
- OMA:   AENREQE
- ProtClustDB:   CLSK791659
- InterPro:   IPR001608
- InterPro:   IPR011078
- PANTHER:   PTHR10146
- PIRSF:   PIRSF004848
- TIGRFAMs:   TIGR00044

Pfam domain/function: PF01168 Ala_racemase_N

EC number: NA

Molecular weight: Translated: 27694; Mature: 27563

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS01211 UPF0001

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAADLSAYPDRESELTHALAAMRSRLAAAAEAAGRNVGEIELLPITKFFPATDVAILFRL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHCCHHHHHHHHHH
GCRSVGESREQEASAKMAELNRLLAAAELGHSGGVHWHMVGRIQRNKAGSLARWAHTAHS
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECEECCCCCCCHHHHHHHHHC
VDSSRLVTALDRAVVAALAEHRRGERLRVYVQVSLDGDGSRGGVDSTTPGAVDRICAQVQ
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
ESEGLELVGLMGIPPLDWDPDEAFDRLQSEHNRVRAMFPHAIGLSAGMSNDLEVAVKHGS
HCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCEEEECCCC
TCVRVGTALLGPRRLRSP
HHHHHHHHHHCCHHCCCC
>Mature Secondary Structure 
AADLSAYPDRESELTHALAAMRSRLAAAAEAAGRNVGEIELLPITKFFPATDVAILFRL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHCCHHHHHHHHHH
GCRSVGESREQEASAKMAELNRLLAAAELGHSGGVHWHMVGRIQRNKAGSLARWAHTAHS
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECEECCCCCCCHHHHHHHHHC
VDSSRLVTALDRAVVAALAEHRRGERLRVYVQVSLDGDGSRGGVDSTTPGAVDRICAQVQ
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
ESEGLELVGLMGIPPLDWDPDEAFDRLQSEHNRVRAMFPHAIGLSAGMSNDLEVAVKHGS
HCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCEEEECCCC
TCVRVGTALLGPRRLRSP
HHHHHHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036