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The map label for this gene is cysQ

Identifier: 121638013

GI number: 121638013

Start: 2372527

End: 2373330

Strand: Reverse

Name: cysQ

Synonym: BCG_2148c

Alternate gene names: 121638013

Gene position: 2373330-2372527 (Counterclockwise)

Preceding gene: 121638015

Following gene: 121638012

Centisome position: 54.25

GC content: 68.28

Gene sequence:

>804_bases
GTGGTGAGCCCTGCCGCACCTGATCTGACGGACGACCTGACTGACGCCGAGCTGGCCGCCGACCTGGCGGCGGACGCGGG
AAAGCTGTTGCTCCAGGTGCGTGCGGAGATCGGTTTCGATCAGCCATGGACGCTCGGGGAAGCCGGTGACCGCCAGGCTA
ACTCGCTGCTGTTGCGACGGCTGCAGGCCGAACGGCCGGGTGACGCAGTGCTCAGTGAGGAGGCCCACGACGATCTGGCC
CGGCTGAAATCCGATCGGGTGTGGATTATTGACCCGTTGGATGGCACCCGCGAGTTCTCCACACCGGGTCGCGACGACTG
GGCGGTACACATTGCGCTGTGGCGGCGTTCCTCCAATGGCCAGCCCGAGATCACCGACGCCGCGGTGGCGTTGCCGGCCC
GTGGCAACGTGGTGTACCGCACCGATACGGTGACTTCCGGCGCCGCGCCGGCCGGCGTTCCTGGCACCTTGCGGATTGCC
GTCAGCGCCACCCGGCCACCGGCAGTCCTGCACCGCATCCGCCAGACGCTGGCGATCCAACCGGTGTCGATCGGTTCGGC
GGGCGCCAAAGCGATGGCCGTCATTGACGGCTACGTCGACGCCTACCTGCACGCCGGAGGCCAATGGGAGTGGGATTCCG
CGGCGCCGGCTGGGGTGATGTTGGCCGCCGGCATGCACGCGTCACGACTCGATGGCTCGCCGCTGCGATACAACCAACTG
GACCCCTACCTGCCGGATCTGCTGATGTGTCGAGCCGAGGTGGCGCCGATCCTGCTCGGTGCCATCGCCGACGCGTGGCG
CTGA

Upstream 100 bases:

>100_bases
TGGTTCGCATCCCACTATTGTGCATCAAGATGCGAATTATAGAGCATCATGATGTGAAGCCCCATTGTCAAATGCCTGCG
TTCAGCTCGGCGATACTGAA

Downstream 100 bases:

>100_bases
TCGGCGCGCGGGCTGCTCAGAAAGGCTGGAGTCACCGGGCCGTTTAGAGTCGAGGACATGCAGTCGTGGTATTGCCCACC
GGTTCCGGTGTTGCCGGGAC

Product: hypothetical protein

Products: NA

Alternate protein names: PAP phosphatase; 3'(2'),5'-bisphosphate nucleotidase; 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; D-fructose-1,6-bisphosphate 1-phosphohydrolase; DPNPase; Fructose-1,6-bisphosphatase; FBPase; Inositol-1-monophosphatase; I-1-Pase; IMPase; Inositol-1-phosphatase

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MVSPAAPDLTDDLTDAELAADLAADAGKLLLQVRAEIGFDQPWTLGEAGDRQANSLLLRRLQAERPGDAVLSEEAHDDLA
RLKSDRVWIIDPLDGTREFSTPGRDDWAVHIALWRRSSNGQPEITDAAVALPARGNVVYRTDTVTSGAAPAGVPGTLRIA
VSATRPPAVLHRIRQTLAIQPVSIGSAGAKAMAVIDGYVDAYLHAGGQWEWDSAAPAGVMLAAGMHASRLDGSPLRYNQL
DPYLPDLLMCRAEVAPILLGAIADAWR

Sequences:

>Translated_267_residues
MVSPAAPDLTDDLTDAELAADLAADAGKLLLQVRAEIGFDQPWTLGEAGDRQANSLLLRRLQAERPGDAVLSEEAHDDLA
RLKSDRVWIIDPLDGTREFSTPGRDDWAVHIALWRRSSNGQPEITDAAVALPARGNVVYRTDTVTSGAAPAGVPGTLRIA
VSATRPPAVLHRIRQTLAIQPVSIGSAGAKAMAVIDGYVDAYLHAGGQWEWDSAAPAGVMLAAGMHASRLDGSPLRYNQL
DPYLPDLLMCRAEVAPILLGAIADAWR
>Mature_267_residues
MVSPAAPDLTDDLTDAELAADLAADAGKLLLQVRAEIGFDQPWTLGEAGDRQANSLLLRRLQAERPGDAVLSEEAHDDLA
RLKSDRVWIIDPLDGTREFSTPGRDDWAVHIALWRRSSNGQPEITDAAVALPARGNVVYRTDTVTSGAAPAGVPGTLRIA
VSATRPPAVLHRIRQTLAIQPVSIGSAGAKAMAVIDGYVDAYLHAGGQWEWDSAAPAGVMLAAGMHASRLDGSPLRYNQL
DPYLPDLLMCRAEVAPILLGAIADAWR

Specific function: Phosphatase with a broad specificity. Its primary physiological function is to dephosphorylate 3'-phosphoadenosine 5'-phosphate (PAP) and 3'-phosphoadenosine 5'-phosphosulfate (PAPS). Thus, plays a role in mycobacterial sulfur metabolism, since it can ser

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Localized On The Inner Face Of The Cytoplasm Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYSQ_MYCBO (P65164)

Other databases:

- EMBL:   BX248341
- RefSeq:   NP_855804.1
- ProteinModelPortal:   P65164
- SMR:   P65164
- EnsemblBacteria:   EBMYCT00000016508
- GeneID:   1091214
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2155c
- GeneTree:   EBGT00050000015695
- HOGENOM:   HBG730251
- OMA:   PARGNIV
- ProtClustDB:   CLSK872017
- BioCyc:   MBOV233413:MB2155C-MONOMER
- InterPro:   IPR020583
- InterPro:   IPR000760
- PANTHER:   PTHR20854

Pfam domain/function: PF00459 Inositol_P

EC number: =3.1.3.7; =3.1.3.11; =3.1.3.25

Molecular weight: Translated: 28447; Mature: 28447

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00629 IMP_1; PS00630 IMP_2

Important sites: BINDING 73-73 BINDING 212-212

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSPAAPDLTDDLTDAELAADLAADAGKLLLQVRAEIGFDQPWTLGEAGDRQANSLLLRR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
LQAERPGDAVLSEEAHDDLARLKSDRVWIIDPLDGTREFSTPGRDDWAVHIALWRRSSNG
HHCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEEECCCC
QPEITDAAVALPARGNVVYRTDTVTSGAAPAGVPGTLRIAVSATRPPAVLHRIRQTLAIQ
CCCCCHHEEEECCCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCC
PVSIGSAGAKAMAVIDGYVDAYLHAGGQWEWDSAAPAGVMLAAGMHASRLDGSPLRYNQL
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHCCCCCCCCCCC
DPYLPDLLMCRAEVAPILLGAIADAWR
CCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVSPAAPDLTDDLTDAELAADLAADAGKLLLQVRAEIGFDQPWTLGEAGDRQANSLLLRR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
LQAERPGDAVLSEEAHDDLARLKSDRVWIIDPLDGTREFSTPGRDDWAVHIALWRRSSNG
HHCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEEECCCC
QPEITDAAVALPARGNVVYRTDTVTSGAAPAGVPGTLRIAVSATRPPAVLHRIRQTLAIQ
CCCCCHHEEEECCCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCC
PVSIGSAGAKAMAVIDGYVDAYLHAGGQWEWDSAAPAGVMLAAGMHASRLDGSPLRYNQL
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHCCCCCCCCCCC
DPYLPDLLMCRAEVAPILLGAIADAWR
CCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972