The gene/protein map for NC_002951 is currently unavailable.
Definition Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome.
Accession NC_008769
Length 4,374,522

Click here to switch to the map view.

The map label for this gene is ucpA [C]

Identifier: 121638011

GI number: 121638011

Start: 2370318

End: 2371199

Strand: Reverse

Name: ucpA [C]

Synonym: BCG_2146c

Alternate gene names: 121638011

Gene position: 2371199-2370318 (Counterclockwise)

Preceding gene: 121638012

Following gene: 121638008

Centisome position: 54.2

GC content: 65.31

Gene sequence:

>882_bases
ATGACATCGCTGCAAGGCAAGGTCGTCTTCATTACCGGTGCTGCCCGGGGAATCGGGGCTGAGGTCGCCCGTCGGCTGCA
CAACAAGGGCGCCAAACTGGTGCTGACCGACCTGAGCAAATCAGAGCTGGCGGTGATGGGCGCCGAACTCGGCGGCGACG
ACCGCCTACTCACCGTGGTAGCCGACGTGCGCGACCTGCCCGCCATGCAGGCCGCAGCCGAGACGGCCGTCGAACGATTC
GGCGGCATCGACGTCGTCGTGGCCAACGCCGGCATCGCCAGCTACGGCTCCGTGCTGAAGGTCGACCCGCAGGCGTTCCG
GCGGGTGTTGGACGTCAATTTGCTGGGTAACTTCCACACGGTGCGGGCGACGTTGCCCGCGCTGATCGACCGCCGCGGTT
ACGTATTGATCGTCTCGTCGCTTGCCGCGTTCGCGGCGCCGCCCGGGATGGCGCCCTACAACATGTCGAAGGCGGGTAAC
GAGCACTTCGCCAACGCGTTGCGACTCGAGGTCGCACACCTGGGCGTCAGCGTCGGCTCGGCGCACATGTCGTGGATCGA
CACCGCGTTGGTTCGCGATACCAAGGCCGACCTGCCTGCGTTCGCCGAATTGCTGGCGCGCCTCCCTTGGCCGTTGAACA
AGACCACGTCGGTCAACAAGTGTGCGGCCGCATTCGTCAACGGCATTGAGGGCCGAAAAGATCGCGTGTACTGCCCGGGC
TGGGTGGCCCTGTTCCGTTGGCTCAAGCCGTTGTTGTCCACCCGGGTAGGCCAACGTCCCATCCGCAACACCGTTGCCAA
GCTGATGCCCCAGATGGATGCCGAGGTCGCCGCGCTCGGCCGCTTTGCCAGCGCCTACACCGAATCACTCGAGAATTCCT
AG

Upstream 100 bases:

>100_bases
TACGGCGGCCACGATGCCGGGGCGCCGAAGTTGGTGGCGACGGCGATCGATGCCCTGCTCGGGGTGGACCTGTAGCCGGC
GCGGCGGTACGTTTTCGGCC

Downstream 100 bases:

>100_bases
AGGTTCTGCCGCGCTCGATTCAGGACAGGTCGCGGAAGGCGAGTGCGAACCCGATCACTCCGATAATGGCAGCGGCGGCG
TAACCGATGATCGACCACCA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVADVRDLPAMQAAAETAVERF
GGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGN
EHFANALRLEVAHLGVSVGSAHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG
WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLENS

Sequences:

>Translated_293_residues
MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVADVRDLPAMQAAAETAVERF
GGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGN
EHFANALRLEVAHLGVSVGSAHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG
WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLENS
>Mature_292_residues
TSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVADVRDLPAMQAAAETAVERFG
GIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNE
HFANALRLEVAHLGVSVGSAHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGW
VALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLENS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=195, Percent_Identity=31.2820512820513, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI32483357, Length=192, Percent_Identity=32.2916666666667, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI210032110, Length=262, Percent_Identity=24.8091603053435, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI126723191, Length=183, Percent_Identity=32.2404371584699, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI7706318, Length=176, Percent_Identity=30.1136363636364, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI4758504, Length=222, Percent_Identity=31.0810810810811, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI150247226, Length=218, Percent_Identity=34.4036697247706, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI142976729, Length=262, Percent_Identity=26.3358778625954, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI157739938, Length=206, Percent_Identity=26.6990291262136, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI83715985, Length=170, Percent_Identity=35.2941176470588, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI32455239, Length=190, Percent_Identity=31.5789473684211, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI5031765, Length=190, Percent_Identity=31.5789473684211, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI4503817, Length=228, Percent_Identity=29.3859649122807, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI19743808, Length=202, Percent_Identity=31.6831683168317, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI44680136, Length=180, Percent_Identity=31.1111111111111, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI44680133, Length=180, Percent_Identity=31.1111111111111, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI17738292, Length=180, Percent_Identity=31.1111111111111, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI33667109, Length=171, Percent_Identity=30.9941520467836, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI5031737, Length=171, Percent_Identity=30.9941520467836, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI40807363, Length=258, Percent_Identity=25.5813953488372, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI38348362, Length=172, Percent_Identity=31.3953488372093, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI38424085, Length=172, Percent_Identity=31.3953488372093, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI302344755, Length=110, Percent_Identity=36.3636363636364, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI40254986, Length=135, Percent_Identity=34.0740740740741, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI40254992, Length=192, Percent_Identity=27.6041666666667, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI50726952, Length=278, Percent_Identity=29.8561151079137, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI4504505, Length=175, Percent_Identity=29.1428571428571, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI87082100, Length=228, Percent_Identity=32.8947368421053, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1787335, Length=208, Percent_Identity=28.3653846153846, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789208, Length=210, Percent_Identity=26.6666666666667, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI2367365, Length=190, Percent_Identity=30, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787820, Length=173, Percent_Identity=28.3236994219653, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790717, Length=210, Percent_Identity=27.1428571428571, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=272, Percent_Identity=25.7352941176471, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=206, Percent_Identity=31.5533980582524, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=204, Percent_Identity=29.4117647058824, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI32563809, Length=205, Percent_Identity=28.2926829268293, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17507613, Length=205, Percent_Identity=28.2926829268293, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17508895, Length=212, Percent_Identity=26.4150943396226, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=210, Percent_Identity=25.7142857142857, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=220, Percent_Identity=24.5454545454545, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=197, Percent_Identity=29.4416243654822, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=195, Percent_Identity=28.2051282051282, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71997402, Length=192, Percent_Identity=27.0833333333333, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=213, Percent_Identity=25.3521126760563, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=189, Percent_Identity=28.042328042328, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=213, Percent_Identity=25.3521126760563, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71982365, Length=144, Percent_Identity=32.6388888888889, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=228, Percent_Identity=28.9473684210526, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=189, Percent_Identity=27.5132275132275, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=210, Percent_Identity=27.6190476190476, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534660, Length=179, Percent_Identity=29.608938547486, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=214, Percent_Identity=25.2336448598131, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17558006, Length=258, Percent_Identity=27.1317829457364, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=292, Percent_Identity=26.7123287671233, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17544670, Length=219, Percent_Identity=27.3972602739726, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=178, Percent_Identity=32.5842696629214, Blast_Score=83, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6322226, Length=166, Percent_Identity=31.3253012048193, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322227, Length=202, Percent_Identity=28.7128712871287, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322861, Length=195, Percent_Identity=30.2564102564103, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI23397609, Length=225, Percent_Identity=34.2222222222222, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI21357041, Length=229, Percent_Identity=31.0043668122271, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24644339, Length=227, Percent_Identity=29.5154185022026, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI28571526, Length=229, Percent_Identity=29.2576419213974, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI21355631, Length=258, Percent_Identity=27.906976744186, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17737361, Length=168, Percent_Identity=32.1428571428571, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=28.2051282051282, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24639444, Length=192, Percent_Identity=31.25, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24644337, Length=254, Percent_Identity=31.1023622047244, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI281364892, Length=211, Percent_Identity=27.0142180094787, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24580925, Length=188, Percent_Identity=27.6595744680851, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24640442, Length=207, Percent_Identity=29.951690821256, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24649181, Length=185, Percent_Identity=27.5675675675676, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI18859837, Length=218, Percent_Identity=29.8165137614679, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24640492, Length=211, Percent_Identity=25.5924170616114, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357673, Length=201, Percent_Identity=28.8557213930348, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221510726, Length=177, Percent_Identity=30.5084745762712, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI116007232, Length=184, Percent_Identity=32.0652173913043, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI116007234, Length=184, Percent_Identity=32.0652173913043, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641232, Length=207, Percent_Identity=26.5700483091787, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24663911, Length=148, Percent_Identity=30.4054054054054, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31332; Mature: 31200

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV
CCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCCCCEEHHH
ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT
HHHHHCHHHHHHHHHHHHHHCCCEEEEECCCCHHCCCEEEECHHHHHHHHHHHHHCCHHH
VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS
HHHHHHHHHCCCCCEEEHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHCH
AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCEECCH
WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLENS
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV
CCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCCCCEEHHH
ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT
HHHHHCHHHHHHHHHHHHHHCCCEEEEECCCCHHCCCEEEECHHHHHHHHHHHHHCCHHH
VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS
HHHHHHHHHCCCCCEEEHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHCH
AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCEECCH
WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLENS
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA