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The map label for this gene is blaC

Identifier: 121637953

GI number: 121637953

Start: 2309538

End: 2310461

Strand: Reverse

Name: blaC

Synonym: BCG_2087c

Alternate gene names: 121637953

Gene position: 2310461-2309538 (Counterclockwise)

Preceding gene: 121637955

Following gene: 121637952

Centisome position: 52.82

GC content: 66.02

Gene sequence:

>924_bases
ATGCGCAACAGAGGATTCGGTCGTCGCGAACTGCTGGTAGCGATGGCAATGCTGGTTTCCGTGACGGGGTGTGCACGGCA
TGCGAGCGGGGCCCGTCCGGCATCGACAACCTTGCCGGCCGGAGCGGATCTGGCGGATCGCTTCGCCGAGCTGGAGCGCA
GATACGATGCCCGGCTTGGGGTGTATGTGCCCGCCACCGGCACCACCGCCGCGATCGAATACCGCGCCGATGAGCGGTTC
GCATTCTGCTCCACGTTCAAGGCGCCGCTCGTGGCGGCGGTGCTGCACCAAAACCCGCTCACGCATCTGGACAAACTGAT
CACCTACACCAGTGACGACATTCGGTCGATCTCCCCGGTGGCCCAACAACACGTTCAGACCGGGATGACGATCGGGCAGC
TTTGCGATGCGGCGATACGCTATAGCGACGGCACCGCCGCCAACCTGTTGCTGGCCGATCTTGGCGGTCCCGGGGGCGGC
ACCGCGGCATTTACCGGCTACCTCCGCAGCTTGGGTGACACCGTGAGCCGGTTGGACGCCGAGGAACCGGAGTTGAACCG
CGATCCGCCCGGGGACGAACGGGATACCACAACACCGCACGCCATCGCCCTGGTGTTGCAGCAGCTTGTTCTCGGCAACG
CGTTGCCGCCCGACAAGCGGGCACTGCTCACCGATTGGATGGCGCGCAACACCACCGGAGCCAAGCGGATCCGAGCGGGC
TTTCCCGCCGATTGGAAGGTGATCGACAAGACCGGGACCGGTGACTACGGACGAGCAAACGACATCGCGGTCGTGTGGTC
ACCGACCGGCGTGCCCTACGTGGTGGCCGTCATGTCCGATCGTGCCGGCGGCGGGTATGACGCCGAGCCCCGTGAGGCGC
TGCTCGCCGAGGCGGCGACGTGCGTTGCCGGTGTGCTTGCATAG

Upstream 100 bases:

>100_bases
CTACGACCGGTCGTCGTAGATCCCGCCGCCGAGCAGCCGGGGGAGCGCGGCGTCGAATGCGCTTTGGCGCCTGCCATCTG
CGCGCGTGTGATACTATGGC

Downstream 100 bases:

>100_bases
GCTCGTGGGACCGAAGTGACCGACGATCATCCGCGCGCCGACATTGTGTCCCGGCAGTACCACCGGTGGTTGTACCCGCA
CCCGATCGCCGATCTTGAGG

Product: class A Beta-lactamase blaC

Products: NA

Alternate protein names: Penicillinase

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MRNRGFGRRELLVAMAMLVSVTGCARHASGARPASTTLPAGADLADRFAELERRYDARLGVYVPATGTTAAIEYRADERF
AFCSTFKAPLVAAVLHQNPLTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGPGGG
TAAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRALLTDWMARNTTGAKRIRAG
FPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDRAGGGYDAEPREALLAEAATCVAGVLA

Sequences:

>Translated_307_residues
MRNRGFGRRELLVAMAMLVSVTGCARHASGARPASTTLPAGADLADRFAELERRYDARLGVYVPATGTTAAIEYRADERF
AFCSTFKAPLVAAVLHQNPLTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGPGGG
TAAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRALLTDWMARNTTGAKRIRAG
FPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDRAGGGYDAEPREALLAEAATCVAGVLA
>Mature_307_residues
MRNRGFGRRELLVAMAMLVSVTGCARHASGARPASTTLPAGADLADRFAELERRYDARLGVYVPATGTTAAIEYRADERF
AFCSTFKAPLVAAVLHQNPLTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGPGGG
TAAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRALLTDWMARNTTGAKRIRAG
FPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDRAGGGYDAEPREALLAEAATCVAGVLA

Specific function: Unknown

COG id: COG2367

COG function: function code V; Beta-lactamase class A

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-A beta-lactamase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BLAC_MYCBO (P0A5I7)

Other databases:

- EMBL:   BX248341
- RefSeq:   NP_855744.1
- ProteinModelPortal:   P0A5I7
- SMR:   P0A5I7
- EnsemblBacteria:   EBMYCT00000015862
- GeneID:   1090361
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2094c
- GeneTree:   EBGT00050000016522
- HOGENOM:   HBG535713
- OMA:   EYGRAND
- ProtClustDB:   CLSK791603
- BioCyc:   MBOV233413:MB2094C-MONOMER
- BRENDA:   3.5.2.6
- InterPro:   IPR012338
- InterPro:   IPR001466
- InterPro:   IPR000871
- PRINTS:   PR00118

Pfam domain/function: PF00144 Beta-lactamase; SSF56601 PBP_transp_fold

EC number: =3.5.2.6

Molecular weight: Translated: 32568; Mature: 32568

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00146 BETA_LACTAMASE_A; PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: ACT_SITE 84-84

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNRGFGRRELLVAMAMLVSVTGCARHASGARPASTTLPAGADLADRFAELERRYDARLG
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCE
VYVPATGTTAAIEYRADERFAFCSTFKAPLVAAVLHQNPLTHLDKLITYTSDDIRSISPV
EEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHH
AQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGPGGGTAAFTGYLRSLGDTVSRLDA
HHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCC
EEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRALLTDWMARNTTGAKRIRAG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHCC
FPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDRAGGGYDAEPREALLAEAAT
CCCCCEEEECCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHH
CVAGVLA
HHHHHCC
>Mature Secondary Structure
MRNRGFGRRELLVAMAMLVSVTGCARHASGARPASTTLPAGADLADRFAELERRYDARLG
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCE
VYVPATGTTAAIEYRADERFAFCSTFKAPLVAAVLHQNPLTHLDKLITYTSDDIRSISPV
EEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHH
AQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGPGGGTAAFTGYLRSLGDTVSRLDA
HHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCC
EEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRALLTDWMARNTTGAKRIRAG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHCC
FPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDRAGGGYDAEPREALLAEAAT
CCCCCEEEECCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHH
CVAGVLA
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972