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The map label for this gene is clcD [H]

Identifier: 121637940

GI number: 121637940

Start: 2296777

End: 2297490

Strand: Direct

Name: clcD [H]

Synonym: BCG_2073

Alternate gene names: 121637940

Gene position: 2296777-2297490 (Clockwise)

Preceding gene: 121637936

Following gene: 121637945

Centisome position: 52.5

GC content: 65.27

Gene sequence:

>714_bases
ATGACAACGATAGAGATCGACGCTCCCGCCGGACCCATTGATGCGCTGCTGGGCCTTCCCCCCGGCCAGGGCCCGTGGCC
GGGTGTGGTGGTGGTGCACGACGCGGTCGGGTATGTCCCCGACAATAAGTTGATTTCCGAGCGTATCGCCCGGGCAGGCT
ATGTGGTGCTCACCCCGAACATGTACGCCCGAGGCGGCCGCGCCCGATGTATCACCCGAGTCTTTCGCGAGCTGTTAACG
AAGCGGGGCCGCGCGCTCGATGACATCCTGGCCGCCCGCGATCACCTGCTGGCCATGCCAGAATGCTCCGGTCGGGTTGG
CATTGTGGGCTTTTGCATGGGCGGTCAGTTTGCGCTTGTCTTGTCGCCCAGAGGTTTTGGCGCCACCGCGCCCTTTTACG
GCACTCCACTGCCGCGCCACCTCAGCGAGACGCTAAACGGGGCATGCCCGATCGTCGCCAGCTTCGGCACCCGCGACCCG
CTGGGTATCGGCGCAGCCAATCGACTACGTAAAGTGACCGCGGCCAAAAACATCCCCGCCGATATCAAGTCCTACCCGGG
CGCCGGGCACAGCTTCGCGAACAAACTGCCCGGTCAGCCGCTGGTGCGCATCGCGGGATTCGGCTACAACGAGGCCGCGA
CCGAAGACGCGTGGCGTCGGGTCTTTGAGTTCTTCGGCCAGCACTTGCGCGCCGGCTCGCCTGGTGAGCCTTAG

Upstream 100 bases:

>100_bases
CGTAGCTGAGCAGCAGCCGCGACACCACGTGACGCCAACGTCTGCGGGCTAGGCCCGAGTTCCTCGGGGGCGGACATCGA
GGCTGCAGTTAGATGACGCT

Downstream 100 bases:

>100_bases
GTACGACTTCGACTCCCCGCGGATGCCGATGACCTTGTCCCGTCGGAGGGCGGCGGGGCTGTCATGTCCGCGTGCACCCC
GAAGGCGAGATGAACATGAT

Product: hypothetical protein

Products: NA

Alternate protein names: Dienelactone hydrolase; DLH [H]

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MTTIEIDAPAGPIDALLGLPPGQGPWPGVVVVHDAVGYVPDNKLISERIARAGYVVLTPNMYARGGRARCITRVFRELLT
KRGRALDDILAARDHLLAMPECSGRVGIVGFCMGGQFALVLSPRGFGATAPFYGTPLPRHLSETLNGACPIVASFGTRDP
LGIGAANRLRKVTAAKNIPADIKSYPGAGHSFANKLPGQPLVRIAGFGYNEAATEDAWRRVFEFFGQHLRAGSPGEP

Sequences:

>Translated_237_residues
MTTIEIDAPAGPIDALLGLPPGQGPWPGVVVVHDAVGYVPDNKLISERIARAGYVVLTPNMYARGGRARCITRVFRELLT
KRGRALDDILAARDHLLAMPECSGRVGIVGFCMGGQFALVLSPRGFGATAPFYGTPLPRHLSETLNGACPIVASFGTRDP
LGIGAANRLRKVTAAKNIPADIKSYPGAGHSFANKLPGQPLVRIAGFGYNEAATEDAWRRVFEFFGQHLRAGSPGEP
>Mature_236_residues
TTIEIDAPAGPIDALLGLPPGQGPWPGVVVVHDAVGYVPDNKLISERIARAGYVVLTPNMYARGGRARCITRVFRELLTK
RGRALDDILAARDHLLAMPECSGRVGIVGFCMGGQFALVLSPRGFGATAPFYGTPLPRHLSETLNGACPIVASFGTRDPL
GIGAANRLRKVTAAKNIPADIKSYPGAGHSFANKLPGQPLVRIAGFGYNEAATEDAWRRVFEFFGQHLRAGSPGEP

Specific function: Ring cleavage of cyclic ester dienelactone to produce maleylacetate [H]

COG id: COG0412

COG function: function code Q; Dienelactone hydrolase and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dienelactone hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI48994982, Length=224, Percent_Identity=27.6785714285714, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002925 [H]

Pfam domain/function: PF01738 DLH [H]

EC number: =3.1.1.45 [H]

Molecular weight: Translated: 25183; Mature: 25052

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIEIDAPAGPIDALLGLPPGQGPWPGVVVVHDAVGYVPDNKLISERIARAGYVVLTPN
CCEEEECCCCCHHHHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCEEEECCC
MYARGGRARCITRVFRELLTKRGRALDDILAARDHLLAMPECSGRVGIVGFCMGGQFALV
HHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEECCCCCCCEEEEEEEECCEEEEE
LSPRGFGATAPFYGTPLPRHLSETLNGACPIVASFGTRDPLGIGAANRLRKVTAAKNIPA
ECCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCCH
DIKSYPGAGHSFANKLPGQPLVRIAGFGYNEAATEDAWRRVFEFFGQHLRAGSPGEP
HHHCCCCCCCHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TTIEIDAPAGPIDALLGLPPGQGPWPGVVVVHDAVGYVPDNKLISERIARAGYVVLTPN
CEEEECCCCCHHHHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCEEEECCC
MYARGGRARCITRVFRELLTKRGRALDDILAARDHLLAMPECSGRVGIVGFCMGGQFALV
HHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEECCCCCCCEEEEEEEECCEEEEE
LSPRGFGATAPFYGTPLPRHLSETLNGACPIVASFGTRDPLGIGAANRLRKVTAAKNIPA
ECCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCCH
DIKSYPGAGHSFANKLPGQPLVRIAGFGYNEAATEDAWRRVFEFFGQHLRAGSPGEP
HHHCCCCCCCHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9495745 [H]