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The map label for this gene is 121637912

Identifier: 121637912

GI number: 121637912

Start: 2255515

End: 2256399

Strand: Reverse

Name: 121637912

Synonym: BCG_2045c

Alternate gene names: NA

Gene position: 2256399-2255515 (Counterclockwise)

Preceding gene: 121637913

Following gene: 121637911

Centisome position: 51.58

GC content: 63.05

Gene sequence:

>885_bases
ATGTCTGCTGCGACAGCGAAATACGGAATACTCGTTGGCGTCGACGGATCAGCGCAATCCAACGCGGCGGTAGCCTGGGC
CGCCCGTGAGGCCGTCATGCGCCAGCTGCCCATCACCCTGCTGCACATTGTTGCCCCTGTGGTTGTCGGCTGGCCGGTGG
GCCAGCTGTACGCGAATATGACTGAGTGGCAAAAGGACAACGCACAGCAGGTCATTGAGCAGGCCCGCGAGGCGCTCACC
AACAGCTTGGGTGAGTCCAAACCGCCGCAGGTGCATACCGAGTTGGTCTTTTCCAATGTTGTGCCGACGCTTATCGATGC
ATCCCAACAGGCTTGGTTGATGGTCGTCGGCAGCCAGGGGATGGGCGCATTGGGTCGACTGCTGCTCGGCTCGATCAGCA
CCGCGTTGCTCCACCATGCGCGGTGTCCAGTGGCCATCATTCATTCCGGTAATGGCGCGACTCCCGACTCCGATGCACCG
GTGTTGGTGGGCATCGACGGATCGCCAGCCTCTGAGGCGGCAACGGCCCTAGCCTTCGACGAAGCCTCCCGCCGAAGGGT
GGACCTGGTGGCGTTGCACGCCTGGACCGATCTGGGGATGTTTCCGGTTCTGGGGATGGATTGGCGAGAGCGCGAGAAGA
GAGAGGCTGAGGTCCTCGCTGAACGCCTCGCCGGCTGGCAAGAGCAGTATCCGGATGTCCGCGTGCACCGATCGCTGGTG
TGCGACAAGCCCGCTCGGTGGCTGCTCGAGCATTCTGAGCAAGCTCAGCTGGTGGTGGTCGGCAGCCATGGGCGCGGGGG
GTTTTCCGGCATGCTGTTGGGTTCGGTGAGTTCCGCGGTAGCCCATTCGGTGAGAATCCCGGTGATCGTCGTCCGTCCCA
GCTAG

Upstream 100 bases:

>100_bases
CACAGTCGAGAACATGCCGACCGGAGGCACCTTGCTGCGGTGGTCTGCACCGCTGCGCTGATGGATTGATGGACTGTGTT
CCGACCGCAAGGAGCGTGAA

Downstream 100 bases:

>100_bases
TACTGGAACCGGCGAGAGCATCCGCTATTATCTGCGTATGAATGCAGATAAAAGAGCTTGCTTGGTGGTCGAACGCGGCC
GATCTGGCCTGCTGTCACAA

Product: hypothetical protein

Products: NA

Alternate protein names: USP Rv2026c

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MSAATAKYGILVGVDGSAQSNAAVAWAAREAVMRQLPITLLHIVAPVVVGWPVGQLYANMTEWQKDNAQQVIEQAREALT
NSLGESKPPQVHTELVFSNVVPTLIDASQQAWLMVVGSQGMGALGRLLLGSISTALLHHARCPVAIIHSGNGATPDSDAP
VLVGIDGSPASEAATALAFDEASRRRVDLVALHAWTDLGMFPVLGMDWREREKREAEVLAERLAGWQEQYPDVRVHRSLV
CDKPARWLLEHSEQAQLVVVGSHGRGGFSGMLLGSVSSAVAHSVRIPVIVVRPS

Sequences:

>Translated_294_residues
MSAATAKYGILVGVDGSAQSNAAVAWAAREAVMRQLPITLLHIVAPVVVGWPVGQLYANMTEWQKDNAQQVIEQAREALT
NSLGESKPPQVHTELVFSNVVPTLIDASQQAWLMVVGSQGMGALGRLLLGSISTALLHHARCPVAIIHSGNGATPDSDAP
VLVGIDGSPASEAATALAFDEASRRRVDLVALHAWTDLGMFPVLGMDWREREKREAEVLAERLAGWQEQYPDVRVHRSLV
CDKPARWLLEHSEQAQLVVVGSHGRGGFSGMLLGSVSSAVAHSVRIPVIVVRPS
>Mature_293_residues
SAATAKYGILVGVDGSAQSNAAVAWAAREAVMRQLPITLLHIVAPVVVGWPVGQLYANMTEWQKDNAQQVIEQAREALTN
SLGESKPPQVHTELVFSNVVPTLIDASQQAWLMVVGSQGMGALGRLLLGSISTALLHHARCPVAIIHSGNGATPDSDAPV
LVGIDGSPASEAATALAFDEASRRRVDLVALHAWTDLGMFPVLGMDWREREKREAEVLAERLAGWQEQYPDVRVHRSLVC
DKPARWLLEHSEQAQLVVVGSHGRGGFSGMLLGSVSSAVAHSVRIPVIVVRPS

Specific function: Unknown

COG id: COG0589

COG function: function code T; Universal stress protein UspA and related nucleotide-binding proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the universal stress protein A family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2026_MYCTU (O53472)

Other databases:

- EMBL:   AE000516
- EMBL:   BX842578
- PIR:   A70942
- RefSeq:   NP_216542.1
- RefSeq:   NP_336550.1
- ProteinModelPortal:   O53472
- SMR:   O53472
- EnsemblBacteria:   EBMYCT00000002579
- EnsemblBacteria:   EBMYCT00000069895
- GeneID:   887460
- GeneID:   924668
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2085
- KEGG:   mtu:Rv2026c
- TIGR:   MT2085
- TubercuList:   Rv2026c
- GeneTree:   EBGT00050000015432
- HOGENOM:   HBG733992
- OMA:   GVFPILG
- ProtClustDB:   CLSK791571
- GO:   GO:0040007
- InterPro:   IPR014729
- InterPro:   IPR006015
- InterPro:   IPR006016
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01438

Pfam domain/function: PF00582 Usp

EC number: NA

Molecular weight: Translated: 31456; Mature: 31325

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAATAKYGILVGVDGSAQSNAAVAWAAREAVMRQLPITLLHIVAPVVVGWPVGQLYANM
CCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHH
TEWQKDNAQQVIEQAREALTNSLGESKPPQVHTELVFSNVVPTLIDASQQAWLMVVGSQG
HHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
MGALGRLLLGSISTALLHHARCPVAIIHSGNGATPDSDAPVLVGIDGSPASEAATALAFD
CHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHH
EASRRRVDLVALHAWTDLGMFPVLGMDWREREKREAEVLAERLAGWQEQYPDVRVHRSLV
HHCCCEEEEEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHH
CDKPARWLLEHSEQAQLVVVGSHGRGGFSGMLLGSVSSAVAHSVRIPVIVVRPS
CCCHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHEECCEEEECCC
>Mature Secondary Structure 
SAATAKYGILVGVDGSAQSNAAVAWAAREAVMRQLPITLLHIVAPVVVGWPVGQLYANM
CCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHH
TEWQKDNAQQVIEQAREALTNSLGESKPPQVHTELVFSNVVPTLIDASQQAWLMVVGSQG
HHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
MGALGRLLLGSISTALLHHARCPVAIIHSGNGATPDSDAPVLVGIDGSPASEAATALAFD
CHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHH
EASRRRVDLVALHAWTDLGMFPVLGMDWREREKREAEVLAERLAGWQEQYPDVRVHRSLV
HHCCCEEEEEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHH
CDKPARWLLEHSEQAQLVVVGSHGRGGFSGMLLGSVSSAVAHSVRIPVIVVRPS
CCCHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHEECCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036