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The map label for this gene is 121637889

Identifier: 121637889

GI number: 121637889

Start: 2229651

End: 2230538

Strand: Reverse

Name: 121637889

Synonym: BCG_2022c

Alternate gene names: NA

Gene position: 2230538-2229651 (Counterclockwise)

Preceding gene: 121637891

Following gene: 121637888

Centisome position: 50.99

GC content: 64.19

Gene sequence:

>888_bases
ATGTCTAAACCCCGCAAGCAGCACGGAGTTGTCGTCGGGGTAGATGGTTCGCTCGAATCGGATGCCGCCGCCTGTTGGGG
TGCCACCGATGCGGCGATGAGGAACATTCCGCTGACCGTGGTCCACGTGGTGAACGCCGATGTAGCGACGTGGCCGCCGA
TGCCGTATCCGGAGACCTGGGGGGTTTGGCAGGAGGACGAGGGTCGCCAGATCGTCGCCAACGCCGTCAAGCTCGCCAAA
GAGGCGGTTGGAGCGGATCGAAAGCTCAGCGTAAAGAGCGAGCTCGTATTTTCCACGCCGGTACCTACCATGGTTGAAAT
CTCCAACGAGGCAGAGATGGTGGTGTTGGGCAGCTCGGGCCGGGGAGCGCTGGCCCGAGGCTTGCTCGGTTCGGTCAGCT
CGAGCCTGGTGCGACGCGCCGGGTGCCCGGTCGCGGTCATCCACAGCGATGATGCGGTGATCCCTGATCCGCAGCACGCT
CCCGTGCTGGTGGGAATCGACGGTTCGCCGGTTTCGGAGCTTGCGACGGCGGTGGCATTTGACGAGGCGTCGCGCCGCGG
CGTCGAACTGATCGCCGTGCACGCGTGGAGTGACGTCGAAGTGGTGGAACTTCCGGGTTTGGACTTCTCGGCTGTACAGC
AGGAAGCGGAGCTTAGTCTCGCCGAACGCTTGGCAGGTTGGCAAGAACGCTATCCCGATGTGCCGGTGAGCCGGGTTGTC
GTTTGCGATCGCCCGGCGCGGAAGCTGGTGCAAAAGTCGGCGTCCGCCCAGCTTGTCGTCGTTGGCAGTCATGGCCGAGG
TGGCTTGACCGGCATGCTTCTGGGGTCGGTCAGTAACGCGGTCTTACACGCCGCGCGGGTGCCAGTGATCGTGGCACGGC
AGTCGTGA

Upstream 100 bases:

>100_bases
AATCCAATCATGGTCGGTTGGCCGTCCGATTGGGGACTAAAGCCTCATGACCGGTGACTGTCCCGGTTCATAGCGTTGCT
CGAGGCGAAGGGAGAATGAG

Downstream 100 bases:

>100_bases
CTACTTGGCTTGGCTACCGCCATGGACTCACCGACCAACGACGGCACGTGTGACGCCCATCCTGTGACAGATGAGCCTTT
CATCGATGTGCGCGAAACCC

Product: hypothetical protein

Products: NA

Alternate protein names: USP Rv2005c

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MSKPRKQHGVVVGVDGSLESDAAACWGATDAAMRNIPLTVVHVVNADVATWPPMPYPETWGVWQEDEGRQIVANAVKLAK
EAVGADRKLSVKSELVFSTPVPTMVEISNEAEMVVLGSSGRGALARGLLGSVSSSLVRRAGCPVAVIHSDDAVIPDPQHA
PVLVGIDGSPVSELATAVAFDEASRRGVELIAVHAWSDVEVVELPGLDFSAVQQEAELSLAERLAGWQERYPDVPVSRVV
VCDRPARKLVQKSASAQLVVVGSHGRGGLTGMLLGSVSNAVLHAARVPVIVARQS

Sequences:

>Translated_295_residues
MSKPRKQHGVVVGVDGSLESDAAACWGATDAAMRNIPLTVVHVVNADVATWPPMPYPETWGVWQEDEGRQIVANAVKLAK
EAVGADRKLSVKSELVFSTPVPTMVEISNEAEMVVLGSSGRGALARGLLGSVSSSLVRRAGCPVAVIHSDDAVIPDPQHA
PVLVGIDGSPVSELATAVAFDEASRRGVELIAVHAWSDVEVVELPGLDFSAVQQEAELSLAERLAGWQERYPDVPVSRVV
VCDRPARKLVQKSASAQLVVVGSHGRGGLTGMLLGSVSNAVLHAARVPVIVARQS
>Mature_294_residues
SKPRKQHGVVVGVDGSLESDAAACWGATDAAMRNIPLTVVHVVNADVATWPPMPYPETWGVWQEDEGRQIVANAVKLAKE
AVGADRKLSVKSELVFSTPVPTMVEISNEAEMVVLGSSGRGALARGLLGSVSSSLVRRAGCPVAVIHSDDAVIPDPQHAP
VLVGIDGSPVSELATAVAFDEASRRGVELIAVHAWSDVEVVELPGLDFSAVQQEAELSLAERLAGWQERYPDVPVSRVVV
CDRPARKLVQKSASAQLVVVGSHGRGGLTGMLLGSVSNAVLHAARVPVIVARQS

Specific function: Unknown

COG id: COG0589

COG function: function code T; Universal stress protein UspA and related nucleotide-binding proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the universal stress protein A family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2005_MYCTU (P64921)

Other databases:

- EMBL:   BX842578
- EMBL:   AE000516
- PIR:   C70759
- RefSeq:   NP_216521.1
- RefSeq:   NP_336524.1
- ProteinModelPortal:   P64921
- SMR:   P64921
- EnsemblBacteria:   EBMYCT00000000364
- EnsemblBacteria:   EBMYCT00000070566
- GeneID:   888831
- GeneID:   923376
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2061
- KEGG:   mtu:Rv2005c
- TIGR:   MT2061
- TubercuList:   Rv2005c
- GeneTree:   EBGT00050000015432
- HOGENOM:   HBG733992
- OMA:   LTIKSEI
- ProtClustDB:   CLSK791556
- InterPro:   IPR014729
- InterPro:   IPR006015
- InterPro:   IPR006016
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01438

Pfam domain/function: PF00582 Usp

EC number: NA

Molecular weight: Translated: 30986; Mature: 30854

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPRKQHGVVVGVDGSLESDAAACWGATDAAMRNIPLTVVHVVNADVATWPPMPYPETW
CCCCCCCCCEEEEECCCCCCCCHHHCCCCHHHHHCCCEEEEEEECCCCCCCCCCCCCCCC
GVWQEDEGRQIVANAVKLAKEAVGADRKLSVKSELVFSTPVPTMVEISNEAEMVVLGSSG
CCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCEEEEECCCCEEEEECCCCCEEEECCCC
RGALARGLLGSVSSSLVRRAGCPVAVIHSDDAVIPDPQHAPVLVGIDGSPVSELATAVAF
CCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHHH
DEASRRGVELIAVHAWSDVEVVELPGLDFSAVQQEAELSLAERLAGWQERYPDVPVSRVV
HHHCCCCEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEE
VCDRPARKLVQKSASAQLVVVGSHGRGGLTGMLLGSVSNAVLHAARVPVIVARQS
EECCHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECC
>Mature Secondary Structure 
SKPRKQHGVVVGVDGSLESDAAACWGATDAAMRNIPLTVVHVVNADVATWPPMPYPETW
CCCCCCCCEEEEECCCCCCCCHHHCCCCHHHHHCCCEEEEEEECCCCCCCCCCCCCCCC
GVWQEDEGRQIVANAVKLAKEAVGADRKLSVKSELVFSTPVPTMVEISNEAEMVVLGSSG
CCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCEEEEECCCCEEEEECCCCCEEEECCCC
RGALARGLLGSVSSSLVRRAGCPVAVIHSDDAVIPDPQHAPVLVGIDGSPVSELATAVAF
CCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHHH
DEASRRGVELIAVHAWSDVEVVELPGLDFSAVQQEAELSLAERLAGWQERYPDVPVSRVV
HHHCCCCEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEE
VCDRPARKLVQKSASAQLVVVGSHGRGGLTGMLLGSVSNAVLHAARVPVIVARQS
EECCHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036