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The map label for this gene is yeeF [C]

Identifier: 121637883

GI number: 121637883

Start: 2222471

End: 2223793

Strand: Reverse

Name: yeeF [C]

Synonym: BCG_2016c

Alternate gene names: 121637883

Gene position: 2223793-2222471 (Counterclockwise)

Preceding gene: 121637887

Following gene: 121637882

Centisome position: 50.84

GC content: 68.63

Gene sequence:

>1323_bases
ATGAGACGCCCGCTAGACCCACGCGATATTCCAGATGAGCTGCGGCGACGGCTGGGGCTCTTGGATGCGGTGGTGATCGG
GCTTGGGTCCATGATCGGTGCCGGAATCTTTGCCGCCCTGGCCCCGGCCGCGTACGCGGCCGGTTCTGGGTTGTTGCTCG
GGTTGGCAGTGGCCGCGGTGGTGGCCTACTGCAATGCGATCTCGTCGGCGCGGCTGGCCGCGCGCTACCCGGCCTCGGGG
GGCACCTATGTGTATGGCCGGATGCGGCTGGGCGACTTCTGGGGATACCTGGCGGGCTGGGGCTTTGTGGTCGGCAAGAC
GGCATCGTGTGCGGCGATGGCGTTGACGGTCGGCTTCTATGTGTGGCCCGCGCAAGCGCACGCGGTGGCCGTCGCCGTGG
TGGTGGCACTGACCGCGGTGAACTACGCCGGGATACAGAAGTCCGCCTGGCTCACCCGGTCGATCGTCGCCGTGGTGTTG
GTGGTCTTGACCGCAGTCGTGGTCGCCGCCTATGGCTCCGGCGCTGCGGACCCGGCGCGACTCGATATCGGTGTAGATGC
ACACGTCTGGGGGATGCTGCAGGCGGCCGGCCTGCTGTTTTTCGCGTTCGCCGGCTATGCCCGCATCGCCACGCTGGGGG
AGGAGGTCCGCGACCCGGCCCGCACGATCCCACGCGCCATCCCGCTGGCGCTGGGCATCACCCTGGCGGTGTATGCCCTG
GTCGCCGTGGCCGTGATCGCTGTGTTGGGTCCGCAGCGGCTCGCGCGGGCCGCCGCCCCGTTGTCGGAGGCCATGAGGGT
CGCGGGGGTGAACTGGCTGATTCCCGTCGTGCAGATAGGGGCCGCGGTGGCCGCATTGGGCTCGCTACTGGCCTTGATTC
TCGGGGTCTCCCGCACCACCTTGGCGATGGCACGCGACCGGCACCTACCGCGCTGGCTGGCCGCCGTGCACCCTAGGTTC
AAGGTGCCCTTTCGTGCCGAACTGGTGGTTGGCGCGGTGGTGGCGGCGCTGGCGGCGACAGCGGATATCCGTGGTGCGAT
CGGCTTTTCGTCCTTCGGTGTGCTGGTCTACTACGCGATCGCCAACGCCTCCGCCTTGACTCTGGGGCTCGACGAGGGCC
GGCCCCGCCGCCTGATTCCGCTGGTGGGACTGATCGGCTGCGTAGTCCTGGCGTTCGCGCTGCCACTCTCCTCGGTGGCC
GCCGGGGCCGCGGTGCTCGGTGTCGGTGTGGCGGCATACGGTGTGCGCCGCATCATCACTCGTCGAGCACGACAGACTGA
TTCTGGTGATACCCAACGAAGTGGTCATCCGTCCGCAACCTAG

Upstream 100 bases:

>100_bases
AAACCCCAAACCCACAAACCCTGGACGCATGCGGGTCTCGGGCGTCAAATTCCGGGTAGATATCGTATACCGATATCGGA
TGCCGTAGCCTTATCGAGGC

Downstream 100 bases:

>100_bases
TTGAATCGGCCAGCGGCGACGGGTCTCACCGACTGACCCTGCTGACGCGGGTCACACATACAATCAGGCCCATCCGCCAG
CAGGGAGGTAGGGAATGAGT

Product: putative integral membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MRRPLDPRDIPDELRRRLGLLDAVVIGLGSMIGAGIFAALAPAAYAAGSGLLLGLAVAAVVAYCNAISSARLAARYPASG
GTYVYGRMRLGDFWGYLAGWGFVVGKTASCAAMALTVGFYVWPAQAHAVAVAVVVALTAVNYAGIQKSAWLTRSIVAVVL
VVLTAVVVAAYGSGAADPARLDIGVDAHVWGMLQAAGLLFFAFAGYARIATLGEEVRDPARTIPRAIPLALGITLAVYAL
VAVAVIAVLGPQRLARAAAPLSEAMRVAGVNWLIPVVQIGAAVAALGSLLALILGVSRTTLAMARDRHLPRWLAAVHPRF
KVPFRAELVVGAVVAALAATADIRGAIGFSSFGVLVYYAIANASALTLGLDEGRPRRLIPLVGLIGCVVLAFALPLSSVA
AGAAVLGVGVAAYGVRRIITRRARQTDSGDTQRSGHPSAT

Sequences:

>Translated_440_residues
MRRPLDPRDIPDELRRRLGLLDAVVIGLGSMIGAGIFAALAPAAYAAGSGLLLGLAVAAVVAYCNAISSARLAARYPASG
GTYVYGRMRLGDFWGYLAGWGFVVGKTASCAAMALTVGFYVWPAQAHAVAVAVVVALTAVNYAGIQKSAWLTRSIVAVVL
VVLTAVVVAAYGSGAADPARLDIGVDAHVWGMLQAAGLLFFAFAGYARIATLGEEVRDPARTIPRAIPLALGITLAVYAL
VAVAVIAVLGPQRLARAAAPLSEAMRVAGVNWLIPVVQIGAAVAALGSLLALILGVSRTTLAMARDRHLPRWLAAVHPRF
KVPFRAELVVGAVVAALAATADIRGAIGFSSFGVLVYYAIANASALTLGLDEGRPRRLIPLVGLIGCVVLAFALPLSSVA
AGAAVLGVGVAAYGVRRIITRRARQTDSGDTQRSGHPSAT
>Mature_440_residues
MRRPLDPRDIPDELRRRLGLLDAVVIGLGSMIGAGIFAALAPAAYAAGSGLLLGLAVAAVVAYCNAISSARLAARYPASG
GTYVYGRMRLGDFWGYLAGWGFVVGKTASCAAMALTVGFYVWPAQAHAVAVAVVVALTAVNYAGIQKSAWLTRSIVAVVL
VVLTAVVVAAYGSGAADPARLDIGVDAHVWGMLQAAGLLFFAFAGYARIATLGEEVRDPARTIPRAIPLALGITLAVYAL
VAVAVIAVLGPQRLARAAAPLSEAMRVAGVNWLIPVVQIGAAVAALGSLLALILGVSRTTLAMARDRHLPRWLAAVHPRF
KVPFRAELVVGAVVAALAATADIRGAIGFSSFGVLVYYAIANASALTLGLDEGRPRRLIPLVGLIGCVVLAFALPLSSVA
AGAAVLGVGVAAYGVRRIITRRARQTDSGDTQRSGHPSAT

Specific function: Probable amino-acid or metabolite transport protein

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily

Homologues:

Organism=Homo sapiens, GI258614003, Length=420, Percent_Identity=27.1428571428571, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI258614005, Length=420, Percent_Identity=27.1428571428571, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI4507047, Length=424, Percent_Identity=26.1792452830189, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI258645169, Length=420, Percent_Identity=27.1428571428571, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI114326544, Length=414, Percent_Identity=27.2946859903382, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI114326550, Length=414, Percent_Identity=27.2946859903382, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI110347453, Length=396, Percent_Identity=27.5252525252525, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI186910308, Length=437, Percent_Identity=25.629290617849, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI186910306, Length=437, Percent_Identity=25.629290617849, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI186910304, Length=437, Percent_Identity=25.629290617849, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI33286428, Length=432, Percent_Identity=27.3148148148148, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI115648063, Length=437, Percent_Identity=25.629290617849, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI115648022, Length=437, Percent_Identity=25.629290617849, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI181337167, Length=390, Percent_Identity=28.4615384615385, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI71979932, Length=360, Percent_Identity=26.9444444444444, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI187423910, Length=396, Percent_Identity=23.2323232323232, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI7657591, Length=396, Percent_Identity=23.2323232323232, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI7657683, Length=406, Percent_Identity=23.6453201970443, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI33286430, Length=216, Percent_Identity=28.2407407407407, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI9790235, Length=434, Percent_Identity=26.9585253456221, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI71999149, Length=366, Percent_Identity=24.0437158469945, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI87082023, Length=398, Percent_Identity=27.8894472361809, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI87082250, Length=454, Percent_Identity=23.1277533039648, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87081869, Length=458, Percent_Identity=27.0742358078603, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1786694, Length=310, Percent_Identity=26.4516129032258, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1786602, Length=316, Percent_Identity=23.4177215189873, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786789, Length=336, Percent_Identity=22.6190476190476, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1786302, Length=353, Percent_Identity=23.2294617563739, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17531343, Length=404, Percent_Identity=26.980198019802, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17532491, Length=433, Percent_Identity=27.0207852193995, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17533459, Length=404, Percent_Identity=25.990099009901, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17540018, Length=414, Percent_Identity=25.3623188405797, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71993915, Length=374, Percent_Identity=22.7272727272727, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32566699, Length=358, Percent_Identity=23.463687150838, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17568033, Length=337, Percent_Identity=27.0029673590504, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24667468, Length=395, Percent_Identity=28.6075949367089, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI281366235, Length=399, Percent_Identity=26.8170426065163, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI116007820, Length=399, Percent_Identity=26.8170426065163, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI221512776, Length=414, Percent_Identity=23.4299516908213, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24666159, Length=414, Percent_Identity=23.4299516908213, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI116007818, Length=392, Percent_Identity=27.0408163265306, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI85725152, Length=392, Percent_Identity=27.0408163265306, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24668806, Length=418, Percent_Identity=26.7942583732057, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI21356285, Length=418, Percent_Identity=26.7942583732057, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24668802, Length=418, Percent_Identity=26.7942583732057, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI221331183, Length=432, Percent_Identity=24.0740740740741, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17647653, Length=432, Percent_Identity=24.0740740740741, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24664379, Length=432, Percent_Identity=24.0740740740741, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI45550968, Length=465, Percent_Identity=22.5806451612903, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI19921172, Length=465, Percent_Identity=22.5806451612903, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21357367, Length=370, Percent_Identity=24.8648648648649, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI161077963, Length=393, Percent_Identity=26.972010178117, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24641995, Length=389, Percent_Identity=23.9074550128535, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641993, Length=382, Percent_Identity=23.5602094240838, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24651635, Length=359, Percent_Identity=23.3983286908078, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24651633, Length=359, Percent_Identity=23.3983286908078, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1999_MYCTU (P63349)

Other databases:

- EMBL:   BX842578
- EMBL:   AE000516
- PIR:   E70758
- RefSeq:   NP_216515.1
- RefSeq:   NP_336518.1
- ProteinModelPortal:   P63349
- EnsemblBacteria:   EBMYCT00000000341
- EnsemblBacteria:   EBMYCT00000072920
- GeneID:   888881
- GeneID:   923385
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2055
- KEGG:   mtu:Rv1999c
- TIGR:   MT2055
- TubercuList:   Rv1999c
- GeneTree:   EBGT00050000015723
- HOGENOM:   HBG727793
- OMA:   NAMSSAR
- ProtClustDB:   CLSK871991
- InterPro:   IPR004841
- InterPro:   IPR002293
- PANTHER:   PTHR11785
- PIRSF:   PIRSF006060

Pfam domain/function: PF00324 AA_permease

EC number: NA

Molecular weight: Translated: 45268; Mature: 45268

Theoretical pI: Translated: 10.82; Mature: 10.82

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x16ba94ec)-; HASH(0x16499e74)-; HASH(0x16b8e4b4)-; HASH(0x1695d8b8)-; HASH(0x16ba8be4)-; HASH(0x15190fa4)-; HASH(0x168130d0)-; HASH(0x167f59b4)-; HASH(0x163d1cb8)-; HASH(0x16709dbc)-; HASH(0x167a50bc)-; HASH(0x1626a834)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRPLDPRDIPDELRRRLGLLDAVVIGLGSMIGAGIFAALAPAAYAAGSGLLLGLAVAAV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
VAYCNAISSARLAARYPASGGTYVYGRMRLGDFWGYLAGWGFVVGKTASCAAMALTVGFY
HHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VWPAQAHAVAVAVVVALTAVNYAGIQKSAWLTRSIVAVVLVVLTAVVVAAYGSGAADPAR
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
LDIGVDAHVWGMLQAAGLLFFAFAGYARIATLGEEVRDPARTIPRAIPLALGITLAVYAL
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
VAVAVIAVLGPQRLARAAAPLSEAMRVAGVNWLIPVVQIGAAVAALGSLLALILGVSRTT
HHHHHHHHHCHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LAMARDRHLPRWLAAVHPRFKVPFRAELVVGAVVAALAATADIRGAIGFSSFGVLVYYAI
HHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ANASALTLGLDEGRPRRLIPLVGLIGCVVLAFALPLSSVAAGAAVLGVGVAAYGVRRIIT
HCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRARQTDSGDTQRSGHPSAT
HHHHCCCCCCCCCCCCCCCH
>Mature Secondary Structure
MRRPLDPRDIPDELRRRLGLLDAVVIGLGSMIGAGIFAALAPAAYAAGSGLLLGLAVAAV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
VAYCNAISSARLAARYPASGGTYVYGRMRLGDFWGYLAGWGFVVGKTASCAAMALTVGFY
HHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VWPAQAHAVAVAVVVALTAVNYAGIQKSAWLTRSIVAVVLVVLTAVVVAAYGSGAADPAR
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
LDIGVDAHVWGMLQAAGLLFFAFAGYARIATLGEEVRDPARTIPRAIPLALGITLAVYAL
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
VAVAVIAVLGPQRLARAAAPLSEAMRVAGVNWLIPVVQIGAAVAALGSLLALILGVSRTT
HHHHHHHHHCHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LAMARDRHLPRWLAAVHPRFKVPFRAELVVGAVVAALAATADIRGAIGFSSFGVLVYYAI
HHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ANASALTLGLDEGRPRRLIPLVGLIGCVVLAFALPLSSVAAGAAVLGVGVAAYGVRRIIT
HCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRARQTDSGDTQRSGHPSAT
HHHHCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036