Click here to switch to the map view.

The map label for this gene is cinA

Identifier: 121637807

GI number: 121637807

Start: 2148692

End: 2149984

Strand: Direct

Name: cinA

Synonym: BCG_1940

Alternate gene names: 121637807

Gene position: 2148692-2149984 (Clockwise)

Preceding gene: 121637804

Following gene: 121637809

Centisome position: 49.12

GC content: 65.97

Gene sequence:

>1293_bases
ATGGCGGTGAGCGCACGTGCGGGCATCGTGATCACCGGAACCGAGGTCCTGACCGGGCGGGTCCAAGACCGCAACGGCCC
CTGGATCGCCGATCGGCTCCTGGAGCTCGGGGTCGAGTTGGCACACATCACGATCTGCGGCGACCGTCCCGCCGACATCG
AGGCACAGCTGCGATTCATGGCTGAGCAGGGTGTGGACCTGATCGTCACCAGCGGCGGCCTGGGGCCGACCGCCGACGAT
ATGACCGTCGAGGTGGTGGCGCGCTATTGCGGGCGCGAGCTGGTGCTGGACGACGAGCTGGAGAACAGGATCGCCAACAT
CCTCAAGAAGCTGATGGGGCGAAATCCCGCTATTGAACCCGCCAACTTCGACTCCATACGCGCCGCCAACCGCAAACAGG
CCATGATTCCGGCCGGATCGCAAGTGATCGATCCGGTGGGCACCGCCCCCGGTCTGGTTGTGCCGGGACGGCCAGCGGTG
ATGGTGCTTCCCGGGCCACCGCGCGAGCTGCAGCCGATATGGAGCAAGGCCATCCAGACGGCTCCGGTACAGGATGCGAT
TGCCGGCCGGACGACCTACCGACAGGAGACCATCCGGATCTTCGGCCTGCCGGAGTCTTCTCTGGCCGACACACTGCGTG
ACGCCGAGGCAGCCATCCCGGGTTTTGACTTAGTCGAGATCACCACCTGCCTGCGGCGCGGCGAGATTGAAATGGTCACT
CGCTTTGAACCGAACGCCGCGCAAGTGTACACGCAATTGGCACGGTTATTGCGCGACCGGCACGGCCACCAGGTCTATTC
GGAAGACGGTGCGTCCGTGGACGAGCTGGTCGCAAAATTGCTAACTGGCCGCCGGATAGCGACCGCCGAATCCTGCACCG
CAGGGTTGCTGGCGGCACGGCTCACCGACCGGCCCGGGTCGTCCAAGTACGTGGCGGGCGCAGTGGTGGCCTACTCTAAC
GAGGCGAAGGCACAGCTTCTCGGTGTGGATCCGGCGCTGATCGAGGCCCACGGGGCGGTTTCCGAGCCGGTCGCCCAGGC
AATGGCAGCGGGGGCGCTGCAAGGCTTCGGCGCCGACACCGCCACCGCGATCACCGGAATTGCGGGTCCGAGTGGGGGAA
CGCCGGAAAAGCCTGTGGGAACAGTGTGCTTCACCGTCCTGCTGGACGATGGCCGAACAACCACCCGAACCGTGCGGCTG
CCCGGGAACCGGTCAGACATTAGGGAGCGCTCGACGACTGTGGCGATGCACCTGCTGCGGCGCACCCTGAGCGGTATCCC
GGGCTCACCCTAG

Upstream 100 bases:

>100_bases
CACCTGGTAGGCGATATCCATGTCGCCGCATTTTGCGTAGCGGGTCCTGTGAATGTGGGGAGCCTGCGCCACGGTCCTAC
GTTAGTTCATGCGTAGGCTC

Downstream 100 bases:

>100_bases
CGACGGCGAAATCGACAGCAGCGCGACAAAGTTCGACGAGAAGACACCGCGCTAATGTCGATTTCGATGACGAACAAGAA
AAGCAGTTTCCGTAGTACCA

Product: competence damage-inducible protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MAVSARAGIVITGTEVLTGRVQDRNGPWIADRLLELGVELAHITICGDRPADIEAQLRFMAEQGVDLIVTSGGLGPTADD
MTVEVVARYCGRELVLDDELENRIANILKKLMGRNPAIEPANFDSIRAANRKQAMIPAGSQVIDPVGTAPGLVVPGRPAV
MVLPGPPRELQPIWSKAIQTAPVQDAIAGRTTYRQETIRIFGLPESSLADTLRDAEAAIPGFDLVEITTCLRRGEIEMVT
RFEPNAAQVYTQLARLLRDRHGHQVYSEDGASVDELVAKLLTGRRIATAESCTAGLLAARLTDRPGSSKYVAGAVVAYSN
EAKAQLLGVDPALIEAHGAVSEPVAQAMAAGALQGFGADTATAITGIAGPSGGTPEKPVGTVCFTVLLDDGRTTTRTVRL
PGNRSDIRERSTTVAMHLLRRTLSGIPGSP

Sequences:

>Translated_430_residues
MAVSARAGIVITGTEVLTGRVQDRNGPWIADRLLELGVELAHITICGDRPADIEAQLRFMAEQGVDLIVTSGGLGPTADD
MTVEVVARYCGRELVLDDELENRIANILKKLMGRNPAIEPANFDSIRAANRKQAMIPAGSQVIDPVGTAPGLVVPGRPAV
MVLPGPPRELQPIWSKAIQTAPVQDAIAGRTTYRQETIRIFGLPESSLADTLRDAEAAIPGFDLVEITTCLRRGEIEMVT
RFEPNAAQVYTQLARLLRDRHGHQVYSEDGASVDELVAKLLTGRRIATAESCTAGLLAARLTDRPGSSKYVAGAVVAYSN
EAKAQLLGVDPALIEAHGAVSEPVAQAMAAGALQGFGADTATAITGIAGPSGGTPEKPVGTVCFTVLLDDGRTTTRTVRL
PGNRSDIRERSTTVAMHLLRRTLSGIPGSP
>Mature_429_residues
AVSARAGIVITGTEVLTGRVQDRNGPWIADRLLELGVELAHITICGDRPADIEAQLRFMAEQGVDLIVTSGGLGPTADDM
TVEVVARYCGRELVLDDELENRIANILKKLMGRNPAIEPANFDSIRAANRKQAMIPAGSQVIDPVGTAPGLVVPGRPAVM
VLPGPPRELQPIWSKAIQTAPVQDAIAGRTTYRQETIRIFGLPESSLADTLRDAEAAIPGFDLVEITTCLRRGEIEMVTR
FEPNAAQVYTQLARLLRDRHGHQVYSEDGASVDELVAKLLTGRRIATAESCTAGLLAARLTDRPGSSKYVAGAVVAYSNE
AKAQLLGVDPALIEAHGAVSEPVAQAMAAGALQGFGADTATAITGIAGPSGGTPEKPVGTVCFTVLLDDGRTTTRTVRLP
GNRSDIRERSTTVAMHLLRRTLSGIPGSP

Specific function: Unknown

COG id: COG1058

COG function: function code R; Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CinA family

Homologues:

Organism=Homo sapiens, GI41872403, Length=98, Percent_Identity=37.7551020408163, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI296434309, Length=98, Percent_Identity=37.7551020408163, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI41872389, Length=98, Percent_Identity=37.7551020408163, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1789052, Length=153, Percent_Identity=45.0980392156863, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1788583, Length=433, Percent_Identity=27.0207852193995, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787818, Length=119, Percent_Identity=38.655462184874, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71993974, Length=298, Percent_Identity=25.503355704698, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71993966, Length=298, Percent_Identity=25.503355704698, Blast_Score=75, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323832, Length=219, Percent_Identity=26.9406392694064, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CINAL_MYCBO (P63776)

Other databases:

- EMBL:   BX248340
- RefSeq:   NP_855587.1
- ProteinModelPortal:   P63776
- SMR:   P63776
- EnsemblBacteria:   EBMYCT00000016032
- GeneID:   1093199
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb1936
- GeneTree:   EBGT00050000017523
- HOGENOM:   HBG449871
- OMA:   NPTVAPY
- ProtClustDB:   PRK00549
- BioCyc:   MBOV233413:MB1936-MONOMER
- HAMAP:   MF_00226_B
- InterPro:   IPR008136
- InterPro:   IPR008135
- InterPro:   IPR001453
- Gene3D:   G3DSA:3.40.980.10
- PIRSF:   PIRSF006728
- SMART:   SM00852
- TIGRFAMs:   TIGR00199
- TIGRFAMs:   TIGR00200

Pfam domain/function: PF02464 CinA; PF00994 MoCF_biosynth; SSF53218 MoCF_biosynth

EC number: NA

Molecular weight: Translated: 45513; Mature: 45381

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSARAGIVITGTEVLTGRVQDRNGPWIADRLLELGVELAHITICGDRPADIEAQLRFM
CCCCCCCCEEEECCCEEEEEEECCCCCHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHH
AEQGVDLIVTSGGLGPTADDMTVEVVARYCGRELVLDDELENRIANILKKLMGRNPAIEP
HHCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHCCCCCCCC
ANFDSIRAANRKQAMIPAGSQVIDPVGTAPGLVVPGRPAVMVLPGPPRELQPIWSKAIQT
CCCCHHHHCCCCCEECCCCCHHCCCCCCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHC
APVQDAIAGRTTYRQETIRIFGLPESSLADTLRDAEAAIPGFDLVEITTCLRRGEIEMVT
CCHHHHHHCCCHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEE
RFEPNAAQVYTQLARLLRDRHGHQVYSEDGASVDELVAKLLTGRRIATAESCTAGLLAAR
EECCCHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHCCCCEECHHHHHHHHHHHH
LTDRPGSSKYVAGAVVAYSNEAKAQLLGVDPALIEAHGAVSEPVAQAMAAGALQGFGADT
HCCCCCCCCEEEEEEEEECCCCCEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCH
ATAITGIAGPSGGTPEKPVGTVCFTVLLDDGRTTTRTVRLPGNRSDIRERSTTVAMHLLR
HHHHEECCCCCCCCCCCCHHHEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
RTLSGIPGSP
HHHCCCCCCC
>Mature Secondary Structure 
AVSARAGIVITGTEVLTGRVQDRNGPWIADRLLELGVELAHITICGDRPADIEAQLRFM
CCCCCCCEEEECCCEEEEEEECCCCCHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHH
AEQGVDLIVTSGGLGPTADDMTVEVVARYCGRELVLDDELENRIANILKKLMGRNPAIEP
HHCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHCCCCCCCC
ANFDSIRAANRKQAMIPAGSQVIDPVGTAPGLVVPGRPAVMVLPGPPRELQPIWSKAIQT
CCCCHHHHCCCCCEECCCCCHHCCCCCCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHC
APVQDAIAGRTTYRQETIRIFGLPESSLADTLRDAEAAIPGFDLVEITTCLRRGEIEMVT
CCHHHHHHCCCHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEE
RFEPNAAQVYTQLARLLRDRHGHQVYSEDGASVDELVAKLLTGRRIATAESCTAGLLAAR
EECCCHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHCCCCEECHHHHHHHHHHHH
LTDRPGSSKYVAGAVVAYSNEAKAQLLGVDPALIEAHGAVSEPVAQAMAAGALQGFGADT
HCCCCCCCCEEEEEEEEECCCCCEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCH
ATAITGIAGPSGGTPEKPVGTVCFTVLLDDGRTTTRTVRLPGNRSDIRERSTTVAMHLLR
HHHHEECCCCCCCCCCCCHHHEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
RTLSGIPGSP
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972