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The map label for this gene is adhB [H]

Identifier: 121637801

GI number: 121637801

Start: 2143826

End: 2144530

Strand: Direct

Name: adhB [H]

Synonym: BCG_1934

Alternate gene names: 121637801

Gene position: 2143826-2144530 (Clockwise)

Preceding gene: 121637800

Following gene: 121637804

Centisome position: 49.01

GC content: 66.24

Gene sequence:

>705_bases
ATGATCTTCGGCGCCGGCGTGCTTGGCGGCGCACAGGCCGATCTGCTGGCGGTGCCGGCCGCCGATTTCCAGGTGCTCAA
GATCCCCGAAGGTATCACCACCGAGCAGGCACTGCTGCTCACGGACAACCTCGCCACCGGTTGGGCGGCAGCCCAACGAG
CCGATATTTCATTCGGCTCCGCCGTGGCGGTCATCGGCCTGGGAGCCGTCGGCCTCTGCGCGCTGCGCAGCGCCTTCATA
CACGGTGCCGCAACGGTTTTCGCTGTCGACCGAGTAAAGGGACGCTTGCAACGCGCGGCCACCTGGGGTGCTACGCCGAT
ACCGTCACCGGCGGCCGAGACGATTCTGGCCGCGACGCGGGGTCGCGGCGCAGACTCGGTGATTGACGCCGTCGGCACCG
ACGCCTCGATGAGCGACGCGCTCAATGCGGTGCGCCCTGGCGGCACCGTCTCGGTTGTCGGCGTGCACGATCTTCAGCCG
TTTCCCCTGCCCGCACTGACGTGCCTGTTGCGAAGCATCACGCTGCGAATGACCATGGCACCGGTACAACGAACCTGGCC
GGAACTGATCCCGTTGCTGCAGTCGGGCCGACTCGATGTCGATGGCATCTTCACTACCACCCTGCCGTTGGACGAAGCGG
CCAAGGGCTATGCAACCGCGAGGGCGCGCTCGGGTGAGGAGCTTAAGGTTCTGCTTACGCCCTGA

Upstream 100 bases:

>100_bases
CCGTCGGAGTTGGCGACCTGGTCATGGTGTCTTCAGTGGCCGGCTGCGGCGTCTGCCCGGGATGCGAACCCATGATCCAG
TCATGTGCTTCTCCGGCCCG

Downstream 100 bases:

>100_bases
CAGCCGTGATGTACTGGGAGCGCATGAAACTGTCGATCTTTACGTCCACGTCCGGCGGTGTCAGTCCGTAGCCGACCTGC
AGCTCGAGGGTGCTGCGGAC

Product: putative dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MIFGAGVLGGAQADLLAVPAADFQVLKIPEGITTEQALLLTDNLATGWAAAQRADISFGSAVAVIGLGAVGLCALRSAFI
HGAATVFAVDRVKGRLQRAATWGATPIPSPAAETILAATRGRGADSVIDAVGTDASMSDALNAVRPGGTVSVVGVHDLQP
FPLPALTCLLRSITLRMTMAPVQRTWPELIPLLQSGRLDVDGIFTTTLPLDEAAKGYATARARSGEELKVLLTP

Sequences:

>Translated_234_residues
MIFGAGVLGGAQADLLAVPAADFQVLKIPEGITTEQALLLTDNLATGWAAAQRADISFGSAVAVIGLGAVGLCALRSAFI
HGAATVFAVDRVKGRLQRAATWGATPIPSPAAETILAATRGRGADSVIDAVGTDASMSDALNAVRPGGTVSVVGVHDLQP
FPLPALTCLLRSITLRMTMAPVQRTWPELIPLLQSGRLDVDGIFTTTLPLDEAAKGYATARARSGEELKVLLTP
>Mature_234_residues
MIFGAGVLGGAQADLLAVPAADFQVLKIPEGITTEQALLLTDNLATGWAAAQRADISFGSAVAVIGLGAVGLCALRSAFI
HGAATVFAVDRVKGRLQRAATWGATPIPSPAAETILAATRGRGADSVIDAVGTDASMSDALNAVRPGGTVSVVGVHDLQP
FPLPALTCLLRSITLRMTMAPVQRTWPELIPLLQSGRLDVDGIFTTTLPLDEAAKGYATARARSGEELKVLLTP

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=215, Percent_Identity=27.906976744186, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI71565152, Length=212, Percent_Identity=27.8301886792453, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1786825, Length=251, Percent_Identity=35.4581673306773, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1788073, Length=202, Percent_Identity=26.7326732673267, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI226510992, Length=230, Percent_Identity=29.5652173913043, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788075, Length=240, Percent_Identity=27.5, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=224, Percent_Identity=25, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319955, Length=222, Percent_Identity=27.027027027027, Blast_Score=75, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6322619, Length=222, Percent_Identity=27.027027027027, Blast_Score=75, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6323099, Length=221, Percent_Identity=25.3393665158371, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17137530, Length=220, Percent_Identity=32.2727272727273, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17737897, Length=222, Percent_Identity=29.2792792792793, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 24075; Mature: 24075

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFGAGVLGGAQADLLAVPAADFQVLKIPEGITTEQALLLTDNLATGWAAAQRADISFGS
CEECCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCEEEEECCCCCCHHHHHHCCCCCCC
AVAVIGLGAVGLCALRSAFIHGAATVFAVDRVKGRLQRAATWGATPIPSPAAETILAATR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
GRGADSVIDAVGTDASMSDALNAVRPGGTVSVVGVHDLQPFPLPALTCLLRSITLRMTMA
CCCHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
PVQRTWPELIPLLQSGRLDVDGIFTTTLPLDEAAKGYATARARSGEELKVLLTP
HHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHCCHHHHHCCCCCEEEEEECC
>Mature Secondary Structure
MIFGAGVLGGAQADLLAVPAADFQVLKIPEGITTEQALLLTDNLATGWAAAQRADISFGS
CEECCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCEEEEECCCCCCHHHHHHCCCCCCC
AVAVIGLGAVGLCALRSAFIHGAATVFAVDRVKGRLQRAATWGATPIPSPAAETILAATR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
GRGADSVIDAVGTDASMSDALNAVRPGGTVSVVGVHDLQPFPLPALTCLLRSITLRMTMA
CCCHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
PVQRTWPELIPLLQSGRLDVDGIFTTTLPLDEAAKGYATARARSGEELKVLLTP
HHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHCCHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141695; 9384377 [H]