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The map label for this gene is PPE28 [H]

Identifier: 121637701

GI number: 121637701

Start: 2040455

End: 2042422

Strand: Direct

Name: PPE28 [H]

Synonym: BCG_1832

Alternate gene names: 121637701

Gene position: 2040455-2042422 (Clockwise)

Preceding gene: 121637700

Following gene: 121637702

Centisome position: 46.64

GC content: 63.77

Gene sequence:

>1968_bases
ATGCTGCCGAATTTCGCGGTGCTGCCCCCCGAGGTCAATTCGGCGAGGGTGTTCGCCGGTGCGGGGTCGGCGCCGATGTT
AGCGGCAGCGGCCGCCTGGGATGATCTAGCCTCCGAGCTGCATTGTGCTGCAATGTCATTCGGGTCGGTTACGTCGGGAT
TGGTGGTTGGGTGGTGGCAGGGATCGGCGTCGGCGGCGATGGTGGACGCAGCCGCGTCGTACATCGGGTGGCTGAGCACG
TCGGCTGCCCACGCCGAGGGCGCGGCCGGTCTGGCTCGGGCCGCGGTATCGGTGTTCGAGGAGGCGCTGGCCGCGACGGT
GCATCCGGCGATGGTTGCGGCAAATCGCGCCCAGGTGGCGTCGCTGGTAGCGTCGAACTTGTTTGGGCAGAACGCGCCTG
CGATCGCCGCGCTCGAATCCTTGTATGAGTGGATGTGGGCCCAGGATGCAGCGGCCATGGCGGGTTATTACGTTGGGGCT
TCGGCGGTGGCCACACAGTTGGCATCGTGGCTGCAACGGCTACAGAGCATCCCCGGCGCCGCCAGTCTTGATGCCCGTCT
GCCGAGCTCGGCCGAGGCACCGATGGGAGTCGTCCGCGCGGTCAACAGCGCGATCGCCGCCAATGCGGCTGCGGCACAAA
CCGTTGGCCTGGTCATGGGAGGCAGCGGCACGCCAATACCGTCGGCCAGATATGTCGAGCTCGCGAACGCGCTGTACATG
AGTGGCAGCGTCCCGGGTGTTATCGCGCAGGCGCTCGTCACGCCCCAAGGGCTCTACCCGGTGGTCGTGATCAAGAACCT
CACTTTCGATTCCTCGGTGGCGCAGGGTGCCGTCATTCTCGAAAGTGCGATTCGGCAGCAAATTGCCGCCGGCAACAACG
TCACCGTCTTCGGCTACTCGCAGAGCGCCACGATCTCGTCACTAGTGATGGCCAATCTTGCGGCTTCGGCCGACCCGCCG
TCTCCAGACGAGCTTTCCTTCACGCTGATCGGCAATCCCAACAACCCCAATGGCGGGGTTGCCACCAGGTTCCCGGGGAT
CTCCTTTCCAAGCTTGGGCGTGACGGCCACCGGGGCCACTCCGCACAATCTGTACCCGACCAAGATCTACACCATCGAAT
ACGACGGCGTCGCCGACTTTCCGCGGTACCCGCTCAACTTTGTGTCGACCCTCAACGCCATTGCCGGCACCTACTACGTG
CACTCCAACTACTTCATCCTGACGCCGGAACAAATTGACGCAGCGGTTCCGCTGACCAATACGGTCGGTCCCACGATGAC
CCAGTACTACATCGTTCGCACGGAGAACCTGCCGCTGCTAGAGCCACTGCGATCGGTGCCGATCGTGGGGAACCCACTGG
CGAACCTGGTTCAACCAAACTTGAAGGTGATTGTTAACCTGGGCTACGGCGACCCGGCCTATGGTTATTCGACCTCGCCG
CCCAATGTTGCGACTCCGTTCGGGTTGTTCCCAGAGGTCAGCCCGGTCGTCATCGCCGACGCTCTCGCCGCCGGGACCCA
GCAGGGAATCGGCGATTTCGCCTACGACGTCAGCCACCTCGAACTGCCGTTGCCGGCAGACGGGTCGACGATGCCAAGCA
CCGCACCGGGCTCGGGTACGCCGGTCCCCCCGCTCTCGATCGACAGCCTGATAGACGACCTGCAGGTGGCTAACCGCAAC
CTCGCCAACACGATTTCGAAGGTGGCCGCGACGAGCTACGCGACGGTGCTCCCAACCGCCGACATCGCCAATGCGGCGTT
GACGATCGTGCCGTCGTACAACATCCACCTTTTTTTGGAGGGCATCCAGCAAGCGCTCAAGGGCGACCCGATGGGACTCG
TCAACGCGGTCGGATACCCACTCGCGGCCGACGTGGCACTGTTCACGGCCGCAGGCGGTCTTCAGCTCTTGATCATCATC
AGCGCGGGCCGAACGATTGCCAATGACATCTCGGCCATTGTCCCCTGA

Upstream 100 bases:

>100_bases
GCCCCGTTCGGGATCTGTACGCACTTTCATCCGACTGCGCGGTTGTTTGTTAGCGCATCGGATGAAAGTGTGCCGTCTCG
GCTGAGGAAGGACCGTCGCG

Downstream 100 bases:

>100_bases
TCGTGTTTTGCGTGAACTTTAAAGCGTTGTGCTGAGGTATGTTCCGCTCGCGTGTGGGGCGGCCCGCGCGACCACCTATG
CATGAGCGCCAATGGTCGAG

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 655; Mature: 655

Protein sequence:

>655_residues
MLPNFAVLPPEVNSARVFAGAGSAPMLAAAAAWDDLASELHCAAMSFGSVTSGLVVGWWQGSASAAMVDAAASYIGWLST
SAAHAEGAAGLARAAVSVFEEALAATVHPAMVAANRAQVASLVASNLFGQNAPAIAALESLYEWMWAQDAAAMAGYYVGA
SAVATQLASWLQRLQSIPGAASLDARLPSSAEAPMGVVRAVNSAIAANAAAAQTVGLVMGGSGTPIPSARYVELANALYM
SGSVPGVIAQALVTPQGLYPVVVIKNLTFDSSVAQGAVILESAIRQQIAAGNNVTVFGYSQSATISSLVMANLAASADPP
SPDELSFTLIGNPNNPNGGVATRFPGISFPSLGVTATGATPHNLYPTKIYTIEYDGVADFPRYPLNFVSTLNAIAGTYYV
HSNYFILTPEQIDAAVPLTNTVGPTMTQYYIVRTENLPLLEPLRSVPIVGNPLANLVQPNLKVIVNLGYGDPAYGYSTSP
PNVATPFGLFPEVSPVVIADALAAGTQQGIGDFAYDVSHLELPLPADGSTMPSTAPGSGTPVPPLSIDSLIDDLQVANRN
LANTISKVAATSYATVLPTADIANAALTIVPSYNIHLFLEGIQQALKGDPMGLVNAVGYPLAADVALFTAAGGLQLLIII
SAGRTIANDISAIVP

Sequences:

>Translated_655_residues
MLPNFAVLPPEVNSARVFAGAGSAPMLAAAAAWDDLASELHCAAMSFGSVTSGLVVGWWQGSASAAMVDAAASYIGWLST
SAAHAEGAAGLARAAVSVFEEALAATVHPAMVAANRAQVASLVASNLFGQNAPAIAALESLYEWMWAQDAAAMAGYYVGA
SAVATQLASWLQRLQSIPGAASLDARLPSSAEAPMGVVRAVNSAIAANAAAAQTVGLVMGGSGTPIPSARYVELANALYM
SGSVPGVIAQALVTPQGLYPVVVIKNLTFDSSVAQGAVILESAIRQQIAAGNNVTVFGYSQSATISSLVMANLAASADPP
SPDELSFTLIGNPNNPNGGVATRFPGISFPSLGVTATGATPHNLYPTKIYTIEYDGVADFPRYPLNFVSTLNAIAGTYYV
HSNYFILTPEQIDAAVPLTNTVGPTMTQYYIVRTENLPLLEPLRSVPIVGNPLANLVQPNLKVIVNLGYGDPAYGYSTSP
PNVATPFGLFPEVSPVVIADALAAGTQQGIGDFAYDVSHLELPLPADGSTMPSTAPGSGTPVPPLSIDSLIDDLQVANRN
LANTISKVAATSYATVLPTADIANAALTIVPSYNIHLFLEGIQQALKGDPMGLVNAVGYPLAADVALFTAAGGLQLLIII
SAGRTIANDISAIVP
>Mature_655_residues
MLPNFAVLPPEVNSARVFAGAGSAPMLAAAAAWDDLASELHCAAMSFGSVTSGLVVGWWQGSASAAMVDAAASYIGWLST
SAAHAEGAAGLARAAVSVFEEALAATVHPAMVAANRAQVASLVASNLFGQNAPAIAALESLYEWMWAQDAAAMAGYYVGA
SAVATQLASWLQRLQSIPGAASLDARLPSSAEAPMGVVRAVNSAIAANAAAAQTVGLVMGGSGTPIPSARYVELANALYM
SGSVPGVIAQALVTPQGLYPVVVIKNLTFDSSVAQGAVILESAIRQQIAAGNNVTVFGYSQSATISSLVMANLAASADPP
SPDELSFTLIGNPNNPNGGVATRFPGISFPSLGVTATGATPHNLYPTKIYTIEYDGVADFPRYPLNFVSTLNAIAGTYYV
HSNYFILTPEQIDAAVPLTNTVGPTMTQYYIVRTENLPLLEPLRSVPIVGNPLANLVQPNLKVIVNLGYGDPAYGYSTSP
PNVATPFGLFPEVSPVVIADALAAGTQQGIGDFAYDVSHLELPLPADGSTMPSTAPGSGTPVPPLSIDSLIDDLQVANRN
LANTISKVAATSYATVLPTADIANAALTIVPSYNIHLFLEGIQQALKGDPMGLVNAVGYPLAADVALFTAAGGLQLLIII
SAGRTIANDISAIVP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013228
- InterPro:   IPR000030 [H]

Pfam domain/function: PF08237 PE-PPE; PF00823 PPE [H]

EC number: NA

Molecular weight: Translated: 67061; Mature: 67061

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPNFAVLPPEVNSARVFAGAGSAPMLAAAAAWDDLASELHCAAMSFGSVTSGLVVGWWQ
CCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
GSASAAMVDAAASYIGWLSTSAAHAEGAAGLARAAVSVFEEALAATVHPAMVAANRAQVA
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLVASNLFGQNAPAIAALESLYEWMWAQDAAAMAGYYVGASAVATQLASWLQRLQSIPGA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ASLDARLPSSAEAPMGVVRAVNSAIAANAAAAQTVGLVMGGSGTPIPSARYVELANALYM
CCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHC
SGSVPGVIAQALVTPQGLYPVVVIKNLTFDSSVAQGAVILESAIRQQIAAGNNVTVFGYS
CCCCHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECC
QSATISSLVMANLAASADPPSPDELSFTLIGNPNNPNGGVATRFPGISFPSLGVTATGAT
CCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCEEECCCCCCCCCCCEEECCCC
PHNLYPTKIYTIEYDGVADFPRYPLNFVSTLNAIAGTYYVHSNYFILTPEQIDAAVPLTN
CCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHEEEEECCEEEECHHHCCCCCCCCC
TVGPTMTQYYIVRTENLPLLEPLRSVPIVGNPLANLVQPNLKVIVNLGYGDPAYGYSTSP
CCCCCCEEEEEEEECCCCHHHHHHCCCCCCCCHHHHCCCCEEEEEECCCCCCCCCCCCCC
PNVATPFGLFPEVSPVVIADALAAGTQQGIGDFAYDVSHLELPLPADGSTMPSTAPGSGT
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHCCHHHEEECCCCCCCCCCCCCCCCCC
PVPPLSIDSLIDDLQVANRNLANTISKVAATSYATVLPTADIANAALTIVPSYNIHLFLE
CCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHEECCCCHHCCCEEEEEECCCEEEHHH
GIQQALKGDPMGLVNAVGYPLAADVALFTAAGGLQLLIIISAGRTIANDISAIVP
HHHHHHCCCCCHHHHHCCCCHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHCCC
>Mature Secondary Structure
MLPNFAVLPPEVNSARVFAGAGSAPMLAAAAAWDDLASELHCAAMSFGSVTSGLVVGWWQ
CCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
GSASAAMVDAAASYIGWLSTSAAHAEGAAGLARAAVSVFEEALAATVHPAMVAANRAQVA
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLVASNLFGQNAPAIAALESLYEWMWAQDAAAMAGYYVGASAVATQLASWLQRLQSIPGA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ASLDARLPSSAEAPMGVVRAVNSAIAANAAAAQTVGLVMGGSGTPIPSARYVELANALYM
CCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHC
SGSVPGVIAQALVTPQGLYPVVVIKNLTFDSSVAQGAVILESAIRQQIAAGNNVTVFGYS
CCCCHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECC
QSATISSLVMANLAASADPPSPDELSFTLIGNPNNPNGGVATRFPGISFPSLGVTATGAT
CCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCEEECCCCCCCCCCCEEECCCC
PHNLYPTKIYTIEYDGVADFPRYPLNFVSTLNAIAGTYYVHSNYFILTPEQIDAAVPLTN
CCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHEEEEECCEEEECHHHCCCCCCCCC
TVGPTMTQYYIVRTENLPLLEPLRSVPIVGNPLANLVQPNLKVIVNLGYGDPAYGYSTSP
CCCCCCEEEEEEEECCCCHHHHHHCCCCCCCCHHHHCCCCEEEEEECCCCCCCCCCCCCC
PNVATPFGLFPEVSPVVIADALAAGTQQGIGDFAYDVSHLELPLPADGSTMPSTAPGSGT
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHCCHHHEEECCCCCCCCCCCCCCCCCC
PVPPLSIDSLIDDLQVANRNLANTISKVAATSYATVLPTADIANAALTIVPSYNIHLFLE
CCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHEECCCCHHCCCEEEEEECCCEEEHHH
GIQQALKGDPMGLVNAVGYPLAADVALFTAAGGLQLLIIISAGRTIANDISAIVP
HHHHHHCCCCCHHHHHCCCCHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]