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The map label for this gene is 121637595

Identifier: 121637595

GI number: 121637595

Start: 1918197

End: 1918808

Strand: Direct

Name: 121637595

Synonym: BCG_1726

Alternate gene names: NA

Gene position: 1918197-1918808 (Clockwise)

Preceding gene: 121637591

Following gene: 121637596

Centisome position: 43.85

GC content: 70.59

Gene sequence:

>612_bases
ATGAACGCTGAGGAACTGGCGATCGACCCGGTCGCGGCCGCGCATCGGCTGCTCGGCGCAACTATTGCCGGACGGGGTGT
GCGTGCGATGGTGGTCGAGGTCGAGGCGTATGGCGGGGTGCCCGACGGTCCCTGGCCGGACGCCGCGGCGCACTCTTACC
GCGGCCGCAATGGCCGCAACGACGTCATGTTCGGGCCCCCGGGGCGGCTTTACACCTACCGCAGCCATGGGATCCATGTC
TGTGCCAACGTCGCGTGCGGGCCCGATGGCACGGCTGCCGCTGTGCTACTTAGGGCCGCCGCCATCGAGGACGGCGCCGA
GCTCGCCACGTCTCGGCGCGGGCAGACGGTGCGCGCTGTCGCACTGGCGCGCGGCCCGGGAAACCTCTGCGCTGCCCTCG
GAATCACCATGGCCGACAACGGGATTGACTTGTTTGATCCGTCCAGTCCGGTGCGGCTGAGGCTCAACGACACGCACCGT
GCCAGGTCGGGGCCGCGCGTTGGGGTCAGTCAAGCCGCTGACCGGCCGTGGCGATTGTGGCTCACGGGTCGACCGGAGGT
GTCGGCCTACCGGCGAAGCTCGCGGGCACCGGCCCGGGGAGCCAGCGACTAG

Upstream 100 bases:

>100_bases
GGCACCGTCGCGAAGTAATTCATCACTTGATGAAATCATCATGTGATGAATATCCGCCAGTCGTGCGGGTTTGTCAAGGG
CCGGTGCACAATCGTCTCTG

Downstream 100 bases:

>100_bases
AGTCTTGCGGGATGTCTGGCATGATCCTCGATGAGCTCAGCTGGCGCGGGTTGATCGCGCAGTCGACCGACCTCGACACG
TTGGCCGCCGAAGCACAGCG

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MNAEELAIDPVAAAHRLLGATIAGRGVRAMVVEVEAYGGVPDGPWPDAAAHSYRGRNGRNDVMFGPPGRLYTYRSHGIHV
CANVACGPDGTAAAVLLRAAAIEDGAELATSRRGQTVRAVALARGPGNLCAALGITMADNGIDLFDPSSPVRLRLNDTHR
ARSGPRVGVSQAADRPWRLWLTGRPEVSAYRRSSRAPARGASD

Sequences:

>Translated_203_residues
MNAEELAIDPVAAAHRLLGATIAGRGVRAMVVEVEAYGGVPDGPWPDAAAHSYRGRNGRNDVMFGPPGRLYTYRSHGIHV
CANVACGPDGTAAAVLLRAAAIEDGAELATSRRGQTVRAVALARGPGNLCAALGITMADNGIDLFDPSSPVRLRLNDTHR
ARSGPRVGVSQAADRPWRLWLTGRPEVSAYRRSSRAPARGASD
>Mature_203_residues
MNAEELAIDPVAAAHRLLGATIAGRGVRAMVVEVEAYGGVPDGPWPDAAAHSYRGRNGRNDVMFGPPGRLYTYRSHGIHV
CANVACGPDGTAAAVLLRAAAIEDGAELATSRRGQTVRAVALARGPGNLCAALGITMADNGIDLFDPSSPVRLRLNDTHR
ARSGPRVGVSQAADRPWRLWLTGRPEVSAYRRSSRAPARGASD

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family

Homologues:

Organism=Homo sapiens, GI62632769, Length=208, Percent_Identity=32.6923076923077, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI62632771, Length=208, Percent_Identity=32.6923076923077, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI62632765, Length=190, Percent_Identity=33.6842105263158, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): 3MGH_MYCBO (P65413)

Other databases:

- EMBL:   BX248339
- RefSeq:   NP_855367.1
- ProteinModelPortal:   P65413
- SMR:   P65413
- EnsemblBacteria:   EBMYCT00000014347
- GeneID:   1092663
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb1714
- GeneTree:   EBGT00050000017493
- HOGENOM:   HBG664239
- OMA:   LCSGPGK
- ProtClustDB:   PRK00802
- BioCyc:   MBOV233413:MB1714-MONOMER
- HAMAP:   MF_00527
- InterPro:   IPR011034
- InterPro:   IPR003180
- Gene3D:   G3DSA:3.10.300.10
- PANTHER:   PTHR10429
- TIGRFAMs:   TIGR00567

Pfam domain/function: PF02245 Pur_DNA_glyco; SSF50486 FMT_C_like

EC number: 3.2.2.-

Molecular weight: Translated: 21340; Mature: 21340

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAEELAIDPVAAAHRLLGATIAGRGVRAMVVEVEAYGGVPDGPWPDAAAHSYRGRNGRN
CCCCHHEECHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCHHHCCCCCCCCC
DVMFGPPGRLYTYRSHGIHVCANVACGPDGTAAAVLLRAAAIEDGAELATSRRGQTVRAV
CEEECCCCCEEEEECCCEEEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHCCCCEEEEE
ALARGPGNLCAALGITMADNGIDLFDPSSPVRLRLNDTHRARSGPRVGVSQAADRPWRLW
EEECCCCCEEEHEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHCCCCEEEE
LTGRPEVSAYRRSSRAPARGASD
EECCCCHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNAEELAIDPVAAAHRLLGATIAGRGVRAMVVEVEAYGGVPDGPWPDAAAHSYRGRNGRN
CCCCHHEECHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCHHHCCCCCCCCC
DVMFGPPGRLYTYRSHGIHVCANVACGPDGTAAAVLLRAAAIEDGAELATSRRGQTVRAV
CEEECCCCCEEEEECCCEEEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHCCCCEEEEE
ALARGPGNLCAALGITMADNGIDLFDPSSPVRLRLNDTHRARSGPRVGVSQAADRPWRLW
EEECCCCCEEEHEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHCCCCEEEE
LTGRPEVSAYRRSSRAPARGASD
EECCCCHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972