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The map label for this gene is pks8 [H]

Identifier: 121637570

GI number: 121637570

Start: 1886971

End: 1891776

Strand: Direct

Name: pks8 [H]

Synonym: BCG_1701

Alternate gene names: 121637570

Gene position: 1886971-1891776 (Clockwise)

Preceding gene: 121637569

Following gene: 121637571

Centisome position: 43.14

GC content: 64.77

Gene sequence:

>4806_bases
ATGTCGGGAACCACCACGCATGTTGACTACCTGAAGCGTCTCACGGCAGATCTGCGGCGCACCCGCAGACGCCTGTCCGA
CTTGGAAGCCAAGTTGTCCGAGCCGGTTGCGGTGGTCGGAATGGGATGCCGTTATCCAGGTGGGGTGGATTCGCCGGAGA
CGTTGTGGGAGCTGGTGGCCCAGGGCCGTGATGCGGTATCGGATTTTCCGGCGGATCGCGGGTGGGATGTGTACGGGTTG
TTTGATCCTGACCCGGATGCATGCGGGAAGATGTATACCCGCCGCGGGACGTTTCTGGAGCATGCGGGTGACTTCGACGC
CGGATTCTTTGGAATCGGTCCTAGCGAGGCGCTGGCGATGGACCCGCAACAGCGCCTGCTATTGGAAGTGTCGTGGGAAG
CGTTGGAGCGTACGGGAATTGACCCGACCAAGTTGCGGGGTTCGGCAACGGGTGTGTTCGCCGGTGTTATCCATGCTGGC
TATGGGGGCCAGCTATCCGGCGAGCTGGAAGGCTATGGGTTAACGGGTTCGACGCTGAGTGTGGCCTCCGGGCGGGTGGC
GTATGTGCTGGGGTTGGAGGGTCCGGCGGTGTCGGTGGACACGGCGTGCTCGTCGTCGTTGGTGGCGCTGCATTTGGCGG
TGCAGTCGCTGCGGTCGGGGGAATGCGATTTGGCGCTGGCCGGTGGGGTGACGGTGATGGCCACCCCCGCCGCATTCGTC
GAGTTCAGCCGGCAGCGGGCGCTGGCGCGCGACGGTCGGTGCAAGGTATACGCCGGTGCCGCCGACGGGACCGCGTGGTC
AGAAGGCGCCGGGGTGCTGGTGGTGGAGCGGCTGGTGGATGCACGGCGGTTGGGGCATCCGGTGCTGGCCCTGGTGCGCG
GATCGGCGGTCAATCAGGACGGCGCCTCCAACGGTTTGACGGCACCCAATGGGCCATCCCAGCAGCGGGTGATTCGGGCG
GCGTTGGCCAGTGCGCGACTGCGCGCGGTTGAGGTGGATGTGGTCGAGGGGCACGGGACCGGGACCATGCTGGGGGATCC
GATTGAGGCGCAGGCGCTTTTGGCGACCTACGGTCAGGACCGCGTTGAGCCCCTGTGGTTGGGGTCGATCAAATCGAACA
TCGGTCATACATCGGCGGCGGCGGGGGTGGCCGGGGTGATCAAGATGGTGCAGGCGATGCGGCATGGGGTGATGCCCAAG
ACATTGCATGTGGATGTTCCTACGCCGCATGTGGATTGGTCGGTGGGGGCGGTGTCGTTGTTGACTCAACCGCGGGCGTG
GTCGGTTCACGGCCGGCCGCGGCGGGCCGGGGTGTCGTCGTTCGGGATCAGCGGCACCAATGCGCATGTGATTCTTGAGC
AGGCACCGGTAGTTGAAAGTGTTGTGCCAGAAGTTGCATCCCCAACAGCGGCGTCCGCCGTGCCGTGGGTGCTGTCGGCC
CGGTCGGAGCAGGCGTTGGCCGGTCAGGCGCAGCGGCTGCTGGCTTTCGTCGCGGCCAACCCGGATTTGGATCCGATCGA
TGTGGGGTGGTCGTTGGTCAAGACGCGGGCGATGTTCGAGCATCGGGCGGTGGTCGTGGGTGCTGATCGCGGGGCCCTGC
TGGCGGGGTTGGCGGCGTTGGCCGCTGGTGAGTCGGGTGCGGGCGTGGCAGTGGGTCGAGCGCGGTCGGTGGGGAAGACG
GTGTTCGTGTTTCCCGGGCAAGGGGCCCAATGGGTAGGCATGGGAGCGCAGTTATATGCCGAATTACCCCTGTTCGCCCT
GGCTTTTGACGCGGTGGCCGAAGAGCTGGATCGGCACCTGCGGCTGCCGCTGCGAAACGTGCTCTGGGAAGGTGACGAGG
CGCTGTTGACTAGCACCGAGTTCGCCCAGCCGGCGTTATTCGCAATCGAAGTGGCGTTGGCAACGTTGTTGCAGCACTGG
GGTATCAGCCCGGATTTCCTGATCGGACATTCGGTGGGCGAGATCGCGGCAGCACATTTGGCCGGGGTGTTGTCGTTGAC
CGATGCGGCGGGTTTGGTGGCTGCCCGCGGCAGGTTGATGGCGGAGTTGCCCGCCGGTGGGGTGATGGTGGTGGCCGCCA
GCGAAGAAGAAGTGCTGCCAGTGCTGGTCGACGGGGCGAATCTCGCGGCGGTCAACGCGCCGCACTCGGTGGTGGTTTCA
GGGTGCGAGGCAGCGGTCAGCGATATTGCCGATCACTTTGCCCGCAGGGGCCGCCGGGTGCATCGGCTAGCGGTATCACA
TGCGTTTCATTCGTTGCTGATGGAACCGATGCTTGCCGAGTTCACGCGGATCGCTGCCGGTATTTCGGTGTCGAAACCGC
GGATTCCGTTGGTGTCCAATGTGACCGGGCAGATGGCCGGCGCAGGCTACGGCGATGGACAGTACTGGGTGGAGCATGCG
CGGCGCCCCGTGCGATTTGTCGAGGGCGTCCAGTTGCTGAATGCGGTTGGGGCCACAAGGTTTGTTGAGGTGGGTCCCGG
CGGTGGCCTGACAGCATTGGTCGAGCAGTCGCTGCCTTTAGGCGAGGCGCTATCGGTGGCGATGATGCGTAGAGAGCACC
CCGAAGTGTCGTCGGTGCTCGGCGCCGTGGCGACATTGTTCACTGCGGGTGCCCAAATGGATTGGCCGGCGGTGTTTGGC
AGTCCGGGTCGACGGATCGAATTGCCGACCTATGCGTTTCAGCGGCAGCGGTATTGGTTGCCGCCTACGTCGGCGGGTTC
GGCAGACATCAGCGGTGTTGGTCTGCTGGCAGCCCGGCATGGTTTGTTGGGTGCGGTTGTGGAGCAACCGGATTCGGACG
TGGTCGTACTGACCGGCCGGCTATCGGTGGGGGAGCAGCGGTGGTTGGCCGATCACGTGATCGCTGGAGTGGTGTTGCTC
GCCGGTGCGGCTTTCGTGGAACTGGCGCTGCGAGCCGCCGACCAGGTGGATTGTGGGGTGGTCGAGGAGCTGACGGTGGT
GACTCCGTTGGTTTTGCCGACGGTGGGCGGGGTGCAGCTACAGGTGGTGGTGGGTGTCGGTGAGATGGGTCAGCGGCCAG
TGTCGATATATTCACGCAACGCTGAGTCGGATTCCGGGTGGGTGTTGCATGCCCGGGGCGTATTGGGGGCAAAGGCGGTT
GCCCCGGCAGCGGATTTGTCGGTGTGGCCGCCGCTGGGTGCTGCCCCGGTTGATGTCGATGGCGCCTATCAGCGATTCGC
CGAACTGGGCTATGAATATGGCCGGGCGTTTCAGGGTCTGACGGCCATGTGGCGGCGGGAATCGGAGCTCTTCGCCGATG
TTGCCGTCCCCGACGATGTCGATGTGACGTTGAGTGGGTTCGGAATTCACCCACTGGTGCTGGATGCGGCCTTGCATGCA
ATGGGCATGGTGGGCGAGCAGGCAGCTACCATGCTGCCCTTCTCCTGGCAAGGGGTCTCCCTGCATGCCGCGGGTGCGTC
CCGGGTTCGGGCGCGGATCGCGCCGGCCGGTGATGGCACGGTGTCGGTGGAGTTGGCCGATCAGGCGGGGTTACCGGTGT
TGTCGGTACAGGCATTGGTCATGCGTTCGGTGTCGTCTCAGCTGTTGTCGGCGGCCGTCGCCGCTGCCGATGCCGCAGGT
CGCGGGTTGTTGGAAGTGGCGTGGTTGCCAGTGGAATTGGCGCACAACGACATCAGCGCCGACCTCGTGGTCTGGGAGTT
GGAGTCTTTCCAGGACGGTGTGGGTCCGGTGTATTCGGCTACGCATCGGGTGTTGGTGGCATTGCAGTCCTGGCTGGCCC
AGGAGCGGGCCGGCGGACTGGTGGTGCTGACCCAAGGGTCGGTCGGCCAGGATGCCACGAACTTGGCCGGCGCCGCGGTG
TGGGGGTTGGTGCGGTCGGCTCAAGCCGAACATCCGGGTCGGGTGATGTTGGTCGATTCGGACGGCTCGATGGATGTTGG
AGATGTCATTGGCTGTGGTGAAGAGCAATTGATGATCCGGAACGGCACAGCCTATGCCGCCCGGCTGGCACAGCTTCGAC
CACAGCCGATCCTGCAGTTGCCCGATACCAACTCGGGCTGGCGGTTGGTCGCCGGCGGCGCGGGCACCCTTGAGGATTTG
ACGTTGGCATCATGCCCTGCAAAGGAATTGGCACCTGGACAGGTTCGAATAGAGGTGCGGGCTTTGGGTGTCAATTTCCG
GGATGTGTTGGTGGCGTTGGGAATATATCCCGGTGCCGCGGAGTTGGGGGCCGAAGGGGCAGGGGTGGTCACCGAAGTCG
GTCCAGGCGTGACCGGTTTAGCAGTTGGTGATCCGGTGATGGGTCTGTTGGGGGTGGCGGGGTCGGAAGCGGTGGTCGAT
GCGCGGCTGGTGGTCAAGCTGCCGAACCGGTGGCCGCTGACCGATGCTGCGGGTGTGCCGGTGGTGTTTCTGACGGCCTA
CTGCGCGTTACGCGTGCTGGCGCAGGTGCAGCCGGGCGAGTCGGTGCTGGTACACGCCGCTGCGGGCGGGGTGGGTATGG
CGGCAGTGCAACTGGCTCGGCTGTGGGGATTGGAGGTTTTCGCTACTGCCAGTCGCGGCAAGTGGGACACGTTGCACACA
ATGGGATGTGACAACACGCATGTTGCCGATTCACGCACACTGGCATTCGAGGAGACGTTTTGGCTGACCACCGAGGGTCG
CGGCGTGGATGTGGTGCTCAACTCGCTGGCCGGTGAGTTCACCGACGCATCGTTGCGGTTACTGCCGCGAGGCGGTCGCT
TCATCGAGATGGGCAAAACCGAGTTCGGGACGCCCAGGTCGTTGCCCAGGACCATCCTGGGGTGGCCTACCGGGCTTTCG
ACTTGA

Upstream 100 bases:

>100_bases
CTGACCACTGAAGACGACGACATCGCCGCCGCGACCGAAAGCCAGCTTTTCGCCATCCTCGACGAGGAACTCGGCTCCTA
ACCCCCCGCAAGGAACACCA

Downstream 100 bases:

>100_bases
TGGAGGCCGGACCGCAGCGGATTGCGCAGATGCTGGCCGAGTTAGTCGAGTTGTTCAAAACTGAAGCGCTGCATCGGCTT
CCAGTCAAGTCATGGGATGT

Product: putative polyketide synthase pks8

Products: NA

Alternate protein names: 6-deoxyerythronolide B synthase II; DEBS 2; ORF 2 [H]

Number of amino acids: Translated: 1601; Mature: 1600

Protein sequence:

>1601_residues
MSGTTTHVDYLKRLTADLRRTRRRLSDLEAKLSEPVAVVGMGCRYPGGVDSPETLWELVAQGRDAVSDFPADRGWDVYGL
FDPDPDACGKMYTRRGTFLEHAGDFDAGFFGIGPSEALAMDPQQRLLLEVSWEALERTGIDPTKLRGSATGVFAGVIHAG
YGGQLSGELEGYGLTGSTLSVASGRVAYVLGLEGPAVSVDTACSSSLVALHLAVQSLRSGECDLALAGGVTVMATPAAFV
EFSRQRALARDGRCKVYAGAADGTAWSEGAGVLVVERLVDARRLGHPVLALVRGSAVNQDGASNGLTAPNGPSQQRVIRA
ALASARLRAVEVDVVEGHGTGTMLGDPIEAQALLATYGQDRVEPLWLGSIKSNIGHTSAAAGVAGVIKMVQAMRHGVMPK
TLHVDVPTPHVDWSVGAVSLLTQPRAWSVHGRPRRAGVSSFGISGTNAHVILEQAPVVESVVPEVASPTAASAVPWVLSA
RSEQALAGQAQRLLAFVAANPDLDPIDVGWSLVKTRAMFEHRAVVVGADRGALLAGLAALAAGESGAGVAVGRARSVGKT
VFVFPGQGAQWVGMGAQLYAELPLFALAFDAVAEELDRHLRLPLRNVLWEGDEALLTSTEFAQPALFAIEVALATLLQHW
GISPDFLIGHSVGEIAAAHLAGVLSLTDAAGLVAARGRLMAELPAGGVMVVAASEEEVLPVLVDGANLAAVNAPHSVVVS
GCEAAVSDIADHFARRGRRVHRLAVSHAFHSLLMEPMLAEFTRIAAGISVSKPRIPLVSNVTGQMAGAGYGDGQYWVEHA
RRPVRFVEGVQLLNAVGATRFVEVGPGGGLTALVEQSLPLGEALSVAMMRREHPEVSSVLGAVATLFTAGAQMDWPAVFG
SPGRRIELPTYAFQRQRYWLPPTSAGSADISGVGLLAARHGLLGAVVEQPDSDVVVLTGRLSVGEQRWLADHVIAGVVLL
AGAAFVELALRAADQVDCGVVEELTVVTPLVLPTVGGVQLQVVVGVGEMGQRPVSIYSRNAESDSGWVLHARGVLGAKAV
APAADLSVWPPLGAAPVDVDGAYQRFAELGYEYGRAFQGLTAMWRRESELFADVAVPDDVDVTLSGFGIHPLVLDAALHA
MGMVGEQAATMLPFSWQGVSLHAAGASRVRARIAPAGDGTVSVELADQAGLPVLSVQALVMRSVSSQLLSAAVAAADAAG
RGLLEVAWLPVELAHNDISADLVVWELESFQDGVGPVYSATHRVLVALQSWLAQERAGGLVVLTQGSVGQDATNLAGAAV
WGLVRSAQAEHPGRVMLVDSDGSMDVGDVIGCGEEQLMIRNGTAYAARLAQLRPQPILQLPDTNSGWRLVAGGAGTLEDL
TLASCPAKELAPGQVRIEVRALGVNFRDVLVALGIYPGAAELGAEGAGVVTEVGPGVTGLAVGDPVMGLLGVAGSEAVVD
ARLVVKLPNRWPLTDAAGVPVVFLTAYCALRVLAQVQPGESVLVHAAAGGVGMAAVQLARLWGLEVFATASRGKWDTLHT
MGCDNTHVADSRTLAFEETFWLTTEGRGVDVVLNSLAGEFTDASLRLLPRGGRFIEMGKTEFGTPRSLPRTILGWPTGLS
T

Sequences:

>Translated_1601_residues
MSGTTTHVDYLKRLTADLRRTRRRLSDLEAKLSEPVAVVGMGCRYPGGVDSPETLWELVAQGRDAVSDFPADRGWDVYGL
FDPDPDACGKMYTRRGTFLEHAGDFDAGFFGIGPSEALAMDPQQRLLLEVSWEALERTGIDPTKLRGSATGVFAGVIHAG
YGGQLSGELEGYGLTGSTLSVASGRVAYVLGLEGPAVSVDTACSSSLVALHLAVQSLRSGECDLALAGGVTVMATPAAFV
EFSRQRALARDGRCKVYAGAADGTAWSEGAGVLVVERLVDARRLGHPVLALVRGSAVNQDGASNGLTAPNGPSQQRVIRA
ALASARLRAVEVDVVEGHGTGTMLGDPIEAQALLATYGQDRVEPLWLGSIKSNIGHTSAAAGVAGVIKMVQAMRHGVMPK
TLHVDVPTPHVDWSVGAVSLLTQPRAWSVHGRPRRAGVSSFGISGTNAHVILEQAPVVESVVPEVASPTAASAVPWVLSA
RSEQALAGQAQRLLAFVAANPDLDPIDVGWSLVKTRAMFEHRAVVVGADRGALLAGLAALAAGESGAGVAVGRARSVGKT
VFVFPGQGAQWVGMGAQLYAELPLFALAFDAVAEELDRHLRLPLRNVLWEGDEALLTSTEFAQPALFAIEVALATLLQHW
GISPDFLIGHSVGEIAAAHLAGVLSLTDAAGLVAARGRLMAELPAGGVMVVAASEEEVLPVLVDGANLAAVNAPHSVVVS
GCEAAVSDIADHFARRGRRVHRLAVSHAFHSLLMEPMLAEFTRIAAGISVSKPRIPLVSNVTGQMAGAGYGDGQYWVEHA
RRPVRFVEGVQLLNAVGATRFVEVGPGGGLTALVEQSLPLGEALSVAMMRREHPEVSSVLGAVATLFTAGAQMDWPAVFG
SPGRRIELPTYAFQRQRYWLPPTSAGSADISGVGLLAARHGLLGAVVEQPDSDVVVLTGRLSVGEQRWLADHVIAGVVLL
AGAAFVELALRAADQVDCGVVEELTVVTPLVLPTVGGVQLQVVVGVGEMGQRPVSIYSRNAESDSGWVLHARGVLGAKAV
APAADLSVWPPLGAAPVDVDGAYQRFAELGYEYGRAFQGLTAMWRRESELFADVAVPDDVDVTLSGFGIHPLVLDAALHA
MGMVGEQAATMLPFSWQGVSLHAAGASRVRARIAPAGDGTVSVELADQAGLPVLSVQALVMRSVSSQLLSAAVAAADAAG
RGLLEVAWLPVELAHNDISADLVVWELESFQDGVGPVYSATHRVLVALQSWLAQERAGGLVVLTQGSVGQDATNLAGAAV
WGLVRSAQAEHPGRVMLVDSDGSMDVGDVIGCGEEQLMIRNGTAYAARLAQLRPQPILQLPDTNSGWRLVAGGAGTLEDL
TLASCPAKELAPGQVRIEVRALGVNFRDVLVALGIYPGAAELGAEGAGVVTEVGPGVTGLAVGDPVMGLLGVAGSEAVVD
ARLVVKLPNRWPLTDAAGVPVVFLTAYCALRVLAQVQPGESVLVHAAAGGVGMAAVQLARLWGLEVFATASRGKWDTLHT
MGCDNTHVADSRTLAFEETFWLTTEGRGVDVVLNSLAGEFTDASLRLLPRGGRFIEMGKTEFGTPRSLPRTILGWPTGLS
T
>Mature_1600_residues
SGTTTHVDYLKRLTADLRRTRRRLSDLEAKLSEPVAVVGMGCRYPGGVDSPETLWELVAQGRDAVSDFPADRGWDVYGLF
DPDPDACGKMYTRRGTFLEHAGDFDAGFFGIGPSEALAMDPQQRLLLEVSWEALERTGIDPTKLRGSATGVFAGVIHAGY
GGQLSGELEGYGLTGSTLSVASGRVAYVLGLEGPAVSVDTACSSSLVALHLAVQSLRSGECDLALAGGVTVMATPAAFVE
FSRQRALARDGRCKVYAGAADGTAWSEGAGVLVVERLVDARRLGHPVLALVRGSAVNQDGASNGLTAPNGPSQQRVIRAA
LASARLRAVEVDVVEGHGTGTMLGDPIEAQALLATYGQDRVEPLWLGSIKSNIGHTSAAAGVAGVIKMVQAMRHGVMPKT
LHVDVPTPHVDWSVGAVSLLTQPRAWSVHGRPRRAGVSSFGISGTNAHVILEQAPVVESVVPEVASPTAASAVPWVLSAR
SEQALAGQAQRLLAFVAANPDLDPIDVGWSLVKTRAMFEHRAVVVGADRGALLAGLAALAAGESGAGVAVGRARSVGKTV
FVFPGQGAQWVGMGAQLYAELPLFALAFDAVAEELDRHLRLPLRNVLWEGDEALLTSTEFAQPALFAIEVALATLLQHWG
ISPDFLIGHSVGEIAAAHLAGVLSLTDAAGLVAARGRLMAELPAGGVMVVAASEEEVLPVLVDGANLAAVNAPHSVVVSG
CEAAVSDIADHFARRGRRVHRLAVSHAFHSLLMEPMLAEFTRIAAGISVSKPRIPLVSNVTGQMAGAGYGDGQYWVEHAR
RPVRFVEGVQLLNAVGATRFVEVGPGGGLTALVEQSLPLGEALSVAMMRREHPEVSSVLGAVATLFTAGAQMDWPAVFGS
PGRRIELPTYAFQRQRYWLPPTSAGSADISGVGLLAARHGLLGAVVEQPDSDVVVLTGRLSVGEQRWLADHVIAGVVLLA
GAAFVELALRAADQVDCGVVEELTVVTPLVLPTVGGVQLQVVVGVGEMGQRPVSIYSRNAESDSGWVLHARGVLGAKAVA
PAADLSVWPPLGAAPVDVDGAYQRFAELGYEYGRAFQGLTAMWRRESELFADVAVPDDVDVTLSGFGIHPLVLDAALHAM
GMVGEQAATMLPFSWQGVSLHAAGASRVRARIAPAGDGTVSVELADQAGLPVLSVQALVMRSVSSQLLSAAVAAADAAGR
GLLEVAWLPVELAHNDISADLVVWELESFQDGVGPVYSATHRVLVALQSWLAQERAGGLVVLTQGSVGQDATNLAGAAVW
GLVRSAQAEHPGRVMLVDSDGSMDVGDVIGCGEEQLMIRNGTAYAARLAQLRPQPILQLPDTNSGWRLVAGGAGTLEDLT
LASCPAKELAPGQVRIEVRALGVNFRDVLVALGIYPGAAELGAEGAGVVTEVGPGVTGLAVGDPVMGLLGVAGSEAVVDA
RLVVKLPNRWPLTDAAGVPVVFLTAYCALRVLAQVQPGESVLVHAAAGGVGMAAVQLARLWGLEVFATASRGKWDTLHTM
GCDNTHVADSRTLAFEETFWLTTEGRGVDVVLNSLAGEFTDASLRLLPRGGRFIEMGKTEFGTPRSLPRTILGWPTGLST

Specific function: Fatty acid biosynthesis. [C]

COG id: COG3321

COG function: function code Q; Polyketide synthase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI41872631, Length=1100, Percent_Identity=28.2727272727273, Blast_Score=322, Evalue=2e-87,
Organism=Homo sapiens, GI18379349, Length=224, Percent_Identity=37.5, Blast_Score=111, Evalue=7e-24,
Organism=Homo sapiens, GI24308257, Length=253, Percent_Identity=33.9920948616601, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI8923559, Length=457, Percent_Identity=25.601750547046, Blast_Score=102, Evalue=3e-21,
Organism=Homo sapiens, GI22538446, Length=229, Percent_Identity=32.3144104803493, Blast_Score=94, Evalue=1e-18,
Organism=Homo sapiens, GI22538444, Length=229, Percent_Identity=32.3144104803493, Blast_Score=94, Evalue=1e-18,
Organism=Homo sapiens, GI194239674, Length=229, Percent_Identity=32.7510917030568, Blast_Score=91, Evalue=1e-17,
Organism=Homo sapiens, GI13236495, Length=229, Percent_Identity=32.7510917030568, Blast_Score=91, Evalue=1e-17,
Organism=Homo sapiens, GI194239676, Length=144, Percent_Identity=38.1944444444444, Blast_Score=81, Evalue=7e-15,
Organism=Homo sapiens, GI67078404, Length=216, Percent_Identity=31.9444444444444, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI67078406, Length=207, Percent_Identity=31.8840579710145, Blast_Score=77, Evalue=2e-13,
Organism=Homo sapiens, GI310129082, Length=101, Percent_Identity=36.6336633663366, Blast_Score=73, Evalue=3e-12,
Organism=Homo sapiens, GI310109937, Length=101, Percent_Identity=36.6336633663366, Blast_Score=73, Evalue=3e-12,
Organism=Homo sapiens, GI239744023, Length=101, Percent_Identity=36.6336633663366, Blast_Score=72, Evalue=3e-12,
Organism=Escherichia coli, GI1787334, Length=289, Percent_Identity=32.5259515570934, Blast_Score=103, Evalue=9e-23,
Organism=Escherichia coli, GI1787337, Length=285, Percent_Identity=28.7719298245614, Blast_Score=92, Evalue=4e-19,
Organism=Escherichia coli, GI1790485, Length=216, Percent_Identity=31.0185185185185, Blast_Score=89, Evalue=3e-18,
Organism=Escherichia coli, GI1788663, Length=289, Percent_Identity=24.9134948096886, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI212642053, Length=1040, Percent_Identity=29.0384615384615, Blast_Score=338, Evalue=1e-92,
Organism=Caenorhabditis elegans, GI17550940, Length=544, Percent_Identity=30.8823529411765, Blast_Score=218, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI71983541, Length=280, Percent_Identity=30.7142857142857, Blast_Score=110, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI71983535, Length=268, Percent_Identity=30.9701492537313, Blast_Score=107, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI71984332, Length=298, Percent_Identity=28.1879194630872, Blast_Score=84, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71987554, Length=185, Percent_Identity=31.8918918918919, Blast_Score=75, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320904, Length=354, Percent_Identity=26.8361581920904, Blast_Score=107, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319520, Length=246, Percent_Identity=30.0813008130081, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19920632, Length=975, Percent_Identity=28.8205128205128, Blast_Score=322, Evalue=2e-87,
Organism=Drosophila melanogaster, GI221330659, Length=975, Percent_Identity=28.8205128205128, Blast_Score=322, Evalue=2e-87,
Organism=Drosophila melanogaster, GI24581345, Length=867, Percent_Identity=29.5271049596309, Blast_Score=293, Evalue=5e-79,
Organism=Drosophila melanogaster, GI24644341, Length=468, Percent_Identity=26.9230769230769, Blast_Score=107, Evalue=7e-23,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR000794
- InterPro:   IPR002198
- InterPro:   IPR015357
- InterPro:   IPR011032
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR020843
- InterPro:   IPR020806
- InterPro:   IPR015083
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF08240 ADH_N; PF00106 adh_short; PF00107 ADH_zinc_N; PF08990 Docking; PF09277 Erythro-docking; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF00550 PP-binding [H]

EC number: =2.3.1.94 [H]

Molecular weight: Translated: 166946; Mature: 166814

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS01162 QOR_ZETA_CRYSTAL ; PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGTTTHVDYLKRLTADLRRTRRRLSDLEAKLSEPVAVVGMGCRYPGGVDSPETLWELVA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHH
QGRDAVSDFPADRGWDVYGLFDPDPDACGKMYTRRGTFLEHAGDFDAGFFGIGPSEALAM
CCCHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCHHHCCCCCCCCEECCCCCHHEEC
DPQQRLLLEVSWEALERTGIDPTKLRGSATGVFAGVIHAGYGGQLSGELEGYGLTGSTLS
CHHHHHEEEEEHHHHHHCCCCHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEE
VASGRVAYVLGLEGPAVSVDTACSSSLVALHLAVQSLRSGECDLALAGGVTVMATPAAFV
ECCCCEEEEEECCCCCEEECHHCCHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCHHHH
EFSRQRALARDGRCKVYAGAADGTAWSEGAGVLVVERLVDARRLGHPVLALVRGSAVNQD
HHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHEEHHCCCCCCCC
GASNGLTAPNGPSQQRVIRAALASARLRAVEVDVVEGHGTGTMLGDPIEAQALLATYGQD
CCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCC
RVEPLWLGSIKSNIGHTSAAAGVAGVIKMVQAMRHGVMPKTLHVDVPTPHVDWSVGAVSL
CCCEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHH
LTQPRAWSVHGRPRRAGVSSFGISGTNAHVILEQAPVVESVVPEVASPTAASAVPWVLSA
HCCCCCEECCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCHHCCCHHHHC
RSEQALAGQAQRLLAFVAANPDLDPIDVGWSLVKTRAMFEHRAVVVGADRGALLAGLAAL
CCHHHHHHHHHHHHHHEECCCCCCCHHCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHHH
AAGESGAGVAVGRARSVGKTVFVFPGQGAQWVGMGAQLYAELPLFALAFDAVAEELDRHL
HCCCCCCCEEECCCCCCCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
RLPLRNVLWEGDEALLTSTEFAQPALFAIEVALATLLQHWGISPDFLIGHSVGEIAAAHL
CCCHHHHHCCCCHHEEECCHHCCHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHH
AGVLSLTDAAGLVAARGRLMAELPAGGVMVVAASEEEVLPVLVDGANLAAVNAPHSVVVS
HHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCCEEEEECCCCEEEECCCHHHHHH
GCEAAVSDIADHFARRGRRVHRLAVSHAFHSLLMEPMLAEFTRIAAGISVSKPRIPLVSN
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECC
VTGQMAGAGYGDGQYWVEHARRPVRFVEGVQLLNAVGATRFVEVGPGGGLTALVEQSLPL
CCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCC
GEALSVAMMRREHPEVSSVLGAVATLFTAGAQMDWPAVFGSPGRRIELPTYAFQRQRYWL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEECCCCCEEECCHHHHHCCEEEC
PPTSAGSADISGVGLLAARHGLLGAVVEQPDSDVVVLTGRLSVGEQRWLADHVIAGVVLL
CCCCCCCCCCCCHHHHHHHHCHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
AGAAFVELALRAADQVDCGVVEELTVVTPLVLPTVGGVQLQVVVGVGEMGQRPVSIYSRN
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCEEEEECC
AESDSGWVLHARGVLGAKAVAPAADLSVWPPLGAAPVDVDGAYQRFAELGYEYGRAFQGL
CCCCCCEEEEECCCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
TAMWRRESELFADVAVPDDVDVTLSGFGIHPLVLDAALHAMGMVGEQAATMLPFSWQGVS
HHHHHHHHHHEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHCCCEECCCEE
LHAAGASRVRARIAPAGDGTVSVELADQAGLPVLSVQALVMRSVSSQLLSAAVAAADAAG
EEECCCHHHEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RGLLEVAWLPVELAHNDISADLVVWELESFQDGVGPVYSATHRVLVALQSWLAQERAGGL
CCEEEEEEEEEEECCCCCCCCEEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCE
VVLTQGSVGQDATNLAGAAVWGLVRSAQAEHPGRVMLVDSDGSMDVGDVIGCGEEQLMIR
EEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHCCCCCEEEEE
NGTAYAARLAQLRPQPILQLPDTNSGWRLVAGGAGTLEDLTLASCPAKELAPGQVRIEVR
CCCHHHHHHHHCCCCCEEECCCCCCCCEEEECCCCCHHHCEECCCCHHHCCCCEEEEEEE
ALGVNFRDVLVALGIYPGAAELGAEGAGVVTEVGPGVTGLAVGDPVMGLLGVAGSEAVVD
EECCCHHHHHHHHHCCCCHHHHCCCCCCEEEECCCCEEEEECCCHHHHHHHCCCCCHHEE
ARLVVKLPNRWPLTDAAGVPVVFLTAYCALRVLAQVQPGESVLVHAAAGGVGMAAVQLAR
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHH
LWGLEVFATASRGKWDTLHTMGCDNTHVADSRTLAFEETFWLTTEGRGVDVVLNSLAGEF
HHCCEEEEECCCCCCCEEEECCCCCCCCCCCCEEEEEEEEEEEECCCCHHHHHHHHCCCC
TDASLRLLPRGGRFIEMGKTEFGTPRSLPRTILGWPTGLST
CCCEEEEEECCCCEEEECCCCCCCCCCCCHHHHCCCCCCCC
>Mature Secondary Structure 
SGTTTHVDYLKRLTADLRRTRRRLSDLEAKLSEPVAVVGMGCRYPGGVDSPETLWELVA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHH
QGRDAVSDFPADRGWDVYGLFDPDPDACGKMYTRRGTFLEHAGDFDAGFFGIGPSEALAM
CCCHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCHHHCCCCCCCCEECCCCCHHEEC
DPQQRLLLEVSWEALERTGIDPTKLRGSATGVFAGVIHAGYGGQLSGELEGYGLTGSTLS
CHHHHHEEEEEHHHHHHCCCCHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEE
VASGRVAYVLGLEGPAVSVDTACSSSLVALHLAVQSLRSGECDLALAGGVTVMATPAAFV
ECCCCEEEEEECCCCCEEECHHCCHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCHHHH
EFSRQRALARDGRCKVYAGAADGTAWSEGAGVLVVERLVDARRLGHPVLALVRGSAVNQD
HHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHEEHHCCCCCCCC
GASNGLTAPNGPSQQRVIRAALASARLRAVEVDVVEGHGTGTMLGDPIEAQALLATYGQD
CCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCC
RVEPLWLGSIKSNIGHTSAAAGVAGVIKMVQAMRHGVMPKTLHVDVPTPHVDWSVGAVSL
CCCEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHH
LTQPRAWSVHGRPRRAGVSSFGISGTNAHVILEQAPVVESVVPEVASPTAASAVPWVLSA
HCCCCCEECCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCHHCCCHHHHC
RSEQALAGQAQRLLAFVAANPDLDPIDVGWSLVKTRAMFEHRAVVVGADRGALLAGLAAL
CCHHHHHHHHHHHHHHEECCCCCCCHHCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHHH
AAGESGAGVAVGRARSVGKTVFVFPGQGAQWVGMGAQLYAELPLFALAFDAVAEELDRHL
HCCCCCCCEEECCCCCCCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
RLPLRNVLWEGDEALLTSTEFAQPALFAIEVALATLLQHWGISPDFLIGHSVGEIAAAHL
CCCHHHHHCCCCHHEEECCHHCCHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHH
AGVLSLTDAAGLVAARGRLMAELPAGGVMVVAASEEEVLPVLVDGANLAAVNAPHSVVVS
HHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCCEEEEECCCCEEEECCCHHHHHH
GCEAAVSDIADHFARRGRRVHRLAVSHAFHSLLMEPMLAEFTRIAAGISVSKPRIPLVSN
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECC
VTGQMAGAGYGDGQYWVEHARRPVRFVEGVQLLNAVGATRFVEVGPGGGLTALVEQSLPL
CCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCC
GEALSVAMMRREHPEVSSVLGAVATLFTAGAQMDWPAVFGSPGRRIELPTYAFQRQRYWL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEECCCCCEEECCHHHHHCCEEEC
PPTSAGSADISGVGLLAARHGLLGAVVEQPDSDVVVLTGRLSVGEQRWLADHVIAGVVLL
CCCCCCCCCCCCHHHHHHHHCHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
AGAAFVELALRAADQVDCGVVEELTVVTPLVLPTVGGVQLQVVVGVGEMGQRPVSIYSRN
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCEEEEECC
AESDSGWVLHARGVLGAKAVAPAADLSVWPPLGAAPVDVDGAYQRFAELGYEYGRAFQGL
CCCCCCEEEEECCCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
TAMWRRESELFADVAVPDDVDVTLSGFGIHPLVLDAALHAMGMVGEQAATMLPFSWQGVS
HHHHHHHHHHEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHCCCEECCCEE
LHAAGASRVRARIAPAGDGTVSVELADQAGLPVLSVQALVMRSVSSQLLSAAVAAADAAG
EEECCCHHHEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RGLLEVAWLPVELAHNDISADLVVWELESFQDGVGPVYSATHRVLVALQSWLAQERAGGL
CCEEEEEEEEEEECCCCCCCCEEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCE
VVLTQGSVGQDATNLAGAAVWGLVRSAQAEHPGRVMLVDSDGSMDVGDVIGCGEEQLMIR
EEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHCCCCCEEEEE
NGTAYAARLAQLRPQPILQLPDTNSGWRLVAGGAGTLEDLTLASCPAKELAPGQVRIEVR
CCCHHHHHHHHCCCCCEEECCCCCCCCEEEECCCCCHHHCEECCCCHHHCCCCEEEEEEE
ALGVNFRDVLVALGIYPGAAELGAEGAGVVTEVGPGVTGLAVGDPVMGLLGVAGSEAVVD
EECCCHHHHHHHHHCCCCHHHHCCCCCCEEEECCCCEEEEECCCHHHHHHHCCCCCHHEE
ARLVVKLPNRWPLTDAAGVPVVFLTAYCALRVLAQVQPGESVLVHAAAGGVGMAAVQLAR
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHH
LWGLEVFATASRGKWDTLHTMGCDNTHVADSRTLAFEETFWLTTEGRGVDVVLNSLAGEF
HHCCEEEEECCCCCCCEEEECCCCCCCCCCCCEEEEEEEEEEEECCCCHHHHHHHHCCCC
TDASLRLLPRGGRFIEMGKTEFGTPRSLPRTILGWPTGLST
CCCEEEEEECCCCEEEECCCCCCCCCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2024119; 1740151 [H]