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The map label for this gene is argG [H]

Identifier: 121637566

GI number: 121637566

Start: 1876630

End: 1877826

Strand: Direct

Name: argG [H]

Synonym: BCG_1697

Alternate gene names: 121637566

Gene position: 1876630-1877826 (Clockwise)

Preceding gene: 121637565

Following gene: 121637567

Centisome position: 42.9

GC content: 67.84

Gene sequence:

>1197_bases
ATGTCAGAGCGCGTCATCCTGGCCTATTCCGGCGGTCTGGACACCTCGGTGGCGATCAGCTGGATAGGCAAGGAGACCGG
CCGTGAGGTGGTGGCGGTGGCGATCGACCTCGGGCAGGGCGGCGAGCACATGGACGTCATACGGCAGCGGGCGCTGGACT
GCGGCGCGGTGGAGGCTGTCGTCGTCGACGCCCGCGACGAGTTCGCCGAAGGCTACTGCCTGCCCACCGTGCTGAACAAC
GCGCTGTACATGGACCGCTACCCGCTGGTGTCGGCGATCAGCCGGCCGCTGATCGTCAAACACCTGGTCGCCGCGGCGCG
CGAGCACGGCGGCGGCATCGTCGCGCACGGCTGCACCGGCAAGGGCAACGACCAGGTCCGGTTCGAAGTCGGGTTCGCCT
CGCTGGCACCGGATTTAGAGGTGTTGGCGCCGGTGCGCGACTACGCGTGGACGCGGGAGAAGGCGATCGCGTTCGCCGAG
GAGAACGCGATCCCGATCAACGTCACCAAACGTTCGCCGTTCTCCATCGACCAGAACGTCTGGGGCCGCGCGGTGGAGAC
CGGCTTCTTAGAGCACCTGTGGAATGCCCCAACCAAGGACATCTACGCCTACACCGAAGACCCCACGATCAACTGGGGGG
TCCCCGACGAGGTGATCGTCGGCTTCGAACGCGGCGTGCCGGTGTCCGTCGACGGCAAGCCGGTGTCGATGCTGGCGGCG
ATCGAGGAGCTCAACCGCCGCGCCGGAGCGCAAGGTGTCGGGCGCCTCGACGTCGTGGAGGATCGGCTGGTGGGCATCAA
GAGCCGCGAGATCTACGAGGCGCCCGGCGCGATGGTGCTGATCACCGCGCACACCGAACTCGAACACGTCACCCTGGAGC
GTGAGCTGGGCCGGTTCAAACGCCAGACCGACCAGCGCTGGGCCGAACTGGTCTACGACGGGCTGTGGTACTCGCCGCTG
AAGGCCGCGCTGGAGGCTTTCGTCGCCAAGACCCAGGAGCACGTGTCCGGCGAGGTGCGGCTGGTGCTACACGGCGGCCA
CATCGCGGTCAACGGCCGGCGCAGCGCGGAATCGTTGTACGACTTCAACCTGGCCACCTACGACGAGGGCGACAGCTTCG
ACCAGTCCGCCGCCCGCGGCTTCGTCTACGTGCACGGGCTGTCCTCCAAGCTCGCCGCCCGCCGGGATCTGCGGTGA

Upstream 100 bases:

>100_bases
GCACCATCGCCGGTGATGACACCATCCTGGTGGTGGCCCGCGAGCCGACGACCGGCGCGCAACTGGCCGGCATGTTCGAG
AACCTTCGGTAAGGAGAGTC

Downstream 100 bases:

>100_bases
CGGTTCTCCCGCGAGCAGACGCAGAATCGCACCGCCACGCCCGTCGGCGTGCGATTCTGCGTCTGCTCGCCACAGAAAAG
TGAGCACCAACGAGGGGTCG

Product: argininosuccinate synthase

Products: NA

Alternate protein names: Citrulline--aspartate ligase [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MSERVILAYSGGLDTSVAISWIGKETGREVVAVAIDLGQGGEHMDVIRQRALDCGAVEAVVVDARDEFAEGYCLPTVLNN
ALYMDRYPLVSAISRPLIVKHLVAAAREHGGGIVAHGCTGKGNDQVRFEVGFASLAPDLEVLAPVRDYAWTREKAIAFAE
ENAIPINVTKRSPFSIDQNVWGRAVETGFLEHLWNAPTKDIYAYTEDPTINWGVPDEVIVGFERGVPVSVDGKPVSMLAA
IEELNRRAGAQGVGRLDVVEDRLVGIKSREIYEAPGAMVLITAHTELEHVTLERELGRFKRQTDQRWAELVYDGLWYSPL
KAALEAFVAKTQEHVSGEVRLVLHGGHIAVNGRRSAESLYDFNLATYDEGDSFDQSAARGFVYVHGLSSKLAARRDLR

Sequences:

>Translated_398_residues
MSERVILAYSGGLDTSVAISWIGKETGREVVAVAIDLGQGGEHMDVIRQRALDCGAVEAVVVDARDEFAEGYCLPTVLNN
ALYMDRYPLVSAISRPLIVKHLVAAAREHGGGIVAHGCTGKGNDQVRFEVGFASLAPDLEVLAPVRDYAWTREKAIAFAE
ENAIPINVTKRSPFSIDQNVWGRAVETGFLEHLWNAPTKDIYAYTEDPTINWGVPDEVIVGFERGVPVSVDGKPVSMLAA
IEELNRRAGAQGVGRLDVVEDRLVGIKSREIYEAPGAMVLITAHTELEHVTLERELGRFKRQTDQRWAELVYDGLWYSPL
KAALEAFVAKTQEHVSGEVRLVLHGGHIAVNGRRSAESLYDFNLATYDEGDSFDQSAARGFVYVHGLSSKLAARRDLR
>Mature_397_residues
SERVILAYSGGLDTSVAISWIGKETGREVVAVAIDLGQGGEHMDVIRQRALDCGAVEAVVVDARDEFAEGYCLPTVLNNA
LYMDRYPLVSAISRPLIVKHLVAAAREHGGGIVAHGCTGKGNDQVRFEVGFASLAPDLEVLAPVRDYAWTREKAIAFAEE
NAIPINVTKRSPFSIDQNVWGRAVETGFLEHLWNAPTKDIYAYTEDPTINWGVPDEVIVGFERGVPVSVDGKPVSMLAAI
EELNRRAGAQGVGRLDVVEDRLVGIKSREIYEAPGAMVLITAHTELEHVTLERELGRFKRQTDQRWAELVYDGLWYSPLK
AALEAFVAKTQEHVSGEVRLVLHGGHIAVNGRRSAESLYDFNLATYDEGDSFDQSAARGFVYVHGLSSKLAARRDLR

Specific function: Arginine biosynthesis; seventh step. [C]

COG id: COG0137

COG function: function code E; Argininosuccinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the argininosuccinate synthase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI53759107, Length=408, Percent_Identity=38.2352941176471, Blast_Score=264, Evalue=1e-70,
Organism=Homo sapiens, GI16950633, Length=408, Percent_Identity=38.2352941176471, Blast_Score=264, Evalue=1e-70,
Organism=Escherichia coli, GI1789563, Length=406, Percent_Identity=30.5418719211823, Blast_Score=120, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6324514, Length=406, Percent_Identity=35.2216748768473, Blast_Score=246, Evalue=4e-66,
Organism=Drosophila melanogaster, GI21358151, Length=400, Percent_Identity=36.25, Blast_Score=251, Evalue=9e-67,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001518
- InterPro:   IPR018223
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00764 Arginosuc_synth [H]

EC number: =6.3.4.5 [H]

Molecular weight: Translated: 43683; Mature: 43552

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00564 ARGININOSUCCIN_SYN_1 ; PS00565 ARGININOSUCCIN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERVILAYSGGLDTSVAISWIGKETGREVVAVAIDLGQGGEHMDVIRQRALDCGAVEAV
CCCCEEEEECCCCCCEEEEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCCEEEE
VVDARDEFAEGYCLPTVLNNALYMDRYPLVSAISRPLIVKHLVAAAREHGGGIVAHGCTG
EEECCHHHHCCEEHHHHHCCCCEECCCHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCC
KGNDQVRFEVGFASLAPDLEVLAPVRDYAWTREKAIAFAEENAIPINVTKRSPFSIDQNV
CCCCEEEEEECHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCCCCCCHHH
WGRAVETGFLEHLWNAPTKDIYAYTEDPTINWGVPDEVIVGFERGVPVSVDGKPVSMLAA
HHHHHHHHHHHHHHCCCCCCEEEEECCCEEECCCCHHHEEEECCCCEEEECCCCHHHHHH
IEELNRRAGAQGVGRLDVVEDRLVGIKSREIYEAPGAMVLITAHTELEHVTLERELGRFK
HHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHCCCCCCEEEEEECCCHHHHHHHHHHHHHH
RQTDQRWAELVYDGLWYSPLKAALEAFVAKTQEHVSGEVRLVLHGGHIAVNGRRSAESLY
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCEEEECCCCCCHHHH
DFNLATYDEGDSFDQSAARGFVYVHGLSSKLAARRDLR
CCCEEECCCCCCCCHHHCCCEEEEECCCHHHHHHCCCC
>Mature Secondary Structure 
SERVILAYSGGLDTSVAISWIGKETGREVVAVAIDLGQGGEHMDVIRQRALDCGAVEAV
CCCEEEEECCCCCCEEEEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCCEEEE
VVDARDEFAEGYCLPTVLNNALYMDRYPLVSAISRPLIVKHLVAAAREHGGGIVAHGCTG
EEECCHHHHCCEEHHHHHCCCCEECCCHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCC
KGNDQVRFEVGFASLAPDLEVLAPVRDYAWTREKAIAFAEENAIPINVTKRSPFSIDQNV
CCCCEEEEEECHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCCCCCCHHH
WGRAVETGFLEHLWNAPTKDIYAYTEDPTINWGVPDEVIVGFERGVPVSVDGKPVSMLAA
HHHHHHHHHHHHHHCCCCCCEEEEECCCEEECCCCHHHEEEECCCCEEEECCCCHHHHHH
IEELNRRAGAQGVGRLDVVEDRLVGIKSREIYEAPGAMVLITAHTELEHVTLERELGRFK
HHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHCCCCCCEEEEEECCCHHHHHHHHHHHHHH
RQTDQRWAELVYDGLWYSPLKAALEAFVAKTQEHVSGEVRLVLHGGHIAVNGRRSAESLY
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCEEEECCCCCCHHHH
DFNLATYDEGDSFDQSAARGFVYVHGLSSKLAARRDLR
CCCEEECCCCCCCCHHHCCCEEEEECCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA