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The map label for this gene is yebQ [C]

Identifier: 121637541

GI number: 121637541

Start: 1844415

End: 1845830

Strand: Direct

Name: yebQ [C]

Synonym: BCG_1672

Alternate gene names: 121637541

Gene position: 1844415-1845830 (Clockwise)

Preceding gene: 121637540

Following gene: 121637543

Centisome position: 42.16

GC content: 67.09

Gene sequence:

>1416_bases
GTGACCGAAACAGCGAGCGAGACCGGCAGCTGGCGTCAGCTACTGAGCAGGTATCTGGGCACCTCCATAGTGCTGGCCGG
TGGCGTCGCGCTGTACGCCACCAACGAGTTTCTGACAATCAGCCTGCTGCCGAGCACAATCGCCGACATCGGGGGTAGCC
GGCTGTACGCCTGGGTGACAACCCTGTATCTGGTCGGGTCGGTGGTGGCGGCGACCACCGTCAATACGATGTTGCTGCGC
GTCGGGGCGCGCTCGTCGTATCTGATGGGGTTGGCCGTCTTCGGTCTGGCCAGCCTGGTATGTGCGGCGGCGCCGAGCAT
GCAGATTCTGGTGGCCGGGCGTACCTTGCAAGGAATAGCCGGTGGGCTGCTGGCCGGCCTAGGCTACGCGCTGATCAACT
CGACCTTGCCCAAGTCGCTGTGGACCCGTGGCTCAGCACTGGTGTCGGCGATGTGGGGGGTCGCGACGCTGATCGGACCG
GCGACCGGAGGCCTTTTCGCGCAGCTCGGGCTGTGGCGATGGGCGTTCGGCGTGATGACGTTGCTGACCGCGTTGATGGC
CATGTTGGTGCCGGTCGCGCTCGGTGCCGGGCGGGTCGGCCCGGGCGGCGAGACGCCGGTGGGCAGCACACACAAGGTGC
CGGTGTGGTCGCTATTGCTGATGGGGGCCGCCGCACTGGCGATCAGCGTCGCCGCGCTTCCGAACTACCTCGTCCAGACG
GCCGGGCTGCTAGCCGCCGCCGCGCTGCTGGTTGCGGTGTTTGTGGTAGTCGACTGGCGGATACACGCAGCGGTGTTGCC
GCCCAGCGTATTTGGCTCCGGACCGTTGAAATGGATTTACCTGACCATGTCGGTGCAGATGATTGCGGCAATGGTCGATA
CCTACGTGCCGCTGTTCGGTCAGCGACTGGGACACCTGACCCCGGTGGCAGCCGGGTTCTTGGGTGCCGCGCTGGCGGTG
GGCTGGACGGTCGGTGAGGTCGCCAGCGCCTCGTTGAACAGTGCACGAGTTATCGGGCATGTCGTGGCAGCCGCACCGCT
GGTGATGGCGTCGGGGTTGGCGCTAGGCGCCGTCACCCAGCGCGCCGATGCGCCGGTGGGGATCATCGCGCTGTGGGCGC
TGGCGCTGCTGATCATCGGGACCGGCATCGGGATCGCCTGGCCGCATCTAACGGTGCGCGCTATGGATTCTGTCGCCGAC
CCGGCCGAGAGCAGCGCGGCGGCCGCGGCGATCAATGTCGTACAGCTGATCTCCGGTGCTTTCGGCGCCGGGCTGGCCGG
TGTGGTGGTCAACACTGCCAAGGGCGGCGAAGTGGCGGCGGCTCGTGGGCTATACATGGCATTTACGGTGCTGGCCGCCG
CTGGTGTCATCGCCTCCTACCAGGCCACGCACCGCGACCGGCGCTTACCGCGTTGA

Upstream 100 bases:

>100_bases
CGGCCGCGCGCGACCTGCAGTTCGAGCTGGCGGCCCGGTTCCGCGACGAGATCGCCGACCTCAAGCGGGAGCTGCGGGGG
ATGGACGCGGCCGGCCTGAA

Downstream 100 bases:

>100_bases
CTTGACCACCTGCGAGTAGTGGAACTGCCAGCGCTCGACGATGCGGAAGCCGAGGTAGCTCGGGAACCGGTATACGGGCG
TGCGCCCGAAGCCTGTTCCC

Product: putative drug efflux membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MTETASETGSWRQLLSRYLGTSIVLAGGVALYATNEFLTISLLPSTIADIGGSRLYAWVTTLYLVGSVVAATTVNTMLLR
VGARSSYLMGLAVFGLASLVCAAAPSMQILVAGRTLQGIAGGLLAGLGYALINSTLPKSLWTRGSALVSAMWGVATLIGP
ATGGLFAQLGLWRWAFGVMTLLTALMAMLVPVALGAGRVGPGGETPVGSTHKVPVWSLLLMGAAALAISVAALPNYLVQT
AGLLAAAALLVAVFVVVDWRIHAAVLPPSVFGSGPLKWIYLTMSVQMIAAMVDTYVPLFGQRLGHLTPVAAGFLGAALAV
GWTVGEVASASLNSARVIGHVVAAAPLVMASGLALGAVTQRADAPVGIIALWALALLIIGTGIGIAWPHLTVRAMDSVAD
PAESSAAAAAINVVQLISGAFGAGLAGVVVNTAKGGEVAAARGLYMAFTVLAAAGVIASYQATHRDRRLPR

Sequences:

>Translated_471_residues
MTETASETGSWRQLLSRYLGTSIVLAGGVALYATNEFLTISLLPSTIADIGGSRLYAWVTTLYLVGSVVAATTVNTMLLR
VGARSSYLMGLAVFGLASLVCAAAPSMQILVAGRTLQGIAGGLLAGLGYALINSTLPKSLWTRGSALVSAMWGVATLIGP
ATGGLFAQLGLWRWAFGVMTLLTALMAMLVPVALGAGRVGPGGETPVGSTHKVPVWSLLLMGAAALAISVAALPNYLVQT
AGLLAAAALLVAVFVVVDWRIHAAVLPPSVFGSGPLKWIYLTMSVQMIAAMVDTYVPLFGQRLGHLTPVAAGFLGAALAV
GWTVGEVASASLNSARVIGHVVAAAPLVMASGLALGAVTQRADAPVGIIALWALALLIIGTGIGIAWPHLTVRAMDSVAD
PAESSAAAAAINVVQLISGAFGAGLAGVVVNTAKGGEVAAARGLYMAFTVLAAAGVIASYQATHRDRRLPR
>Mature_470_residues
TETASETGSWRQLLSRYLGTSIVLAGGVALYATNEFLTISLLPSTIADIGGSRLYAWVTTLYLVGSVVAATTVNTMLLRV
GARSSYLMGLAVFGLASLVCAAAPSMQILVAGRTLQGIAGGLLAGLGYALINSTLPKSLWTRGSALVSAMWGVATLIGPA
TGGLFAQLGLWRWAFGVMTLLTALMAMLVPVALGAGRVGPGGETPVGSTHKVPVWSLLLMGAAALAISVAALPNYLVQTA
GLLAAAALLVAVFVVVDWRIHAAVLPPSVFGSGPLKWIYLTMSVQMIAAMVDTYVPLFGQRLGHLTPVAAGFLGAALAVG
WTVGEVASASLNSARVIGHVVAAAPLVMASGLALGAVTQRADAPVGIIALWALALLIIGTGIGIAWPHLTVRAMDSVADP
AESSAAAAAINVVQLISGAFGAGLAGVVVNTAKGGEVAAARGLYMAFTVLAAAGVIASYQATHRDRRLPR

Specific function: Could be involved in fluoroquinolones efflux [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=134, Percent_Identity=30.5970149253731, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47812; Mature: 47681

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETASETGSWRQLLSRYLGTSIVLAGGVALYATNEFLTISLLPSTIADIGGSRLYAWVT
CCCCCCCCCHHHHHHHHHHCCHHHHHCCEEEEEECCEEEEEECHHHHHHCCCCHHHHHHH
TLYLVGSVVAATTVNTMLLRVGARSSYLMGLAVFGLASLVCAAAPSMQILVAGRTLQGIA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHH
GGLLAGLGYALINSTLPKSLWTRGSALVSAMWGVATLIGPATGGLFAQLGLWRWAFGVMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LLTALMAMLVPVALGAGRVGPGGETPVGSTHKVPVWSLLLMGAAALAISVAALPNYLVQT
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLLAAAALLVAVFVVVDWRIHAAVLPPSVFGSGPLKWIYLTMSVQMIAAMVDTYVPLFG
HHHHHHHHHHHHHHHHHHHHHHEEECCCHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
QRLGHLTPVAAGFLGAALAVGWTVGEVASASLNSARVIGHVVAAAPLVMASGLALGAVTQ
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
RADAPVGIIALWALALLIIGTGIGIAWPHLTVRAMDSVADPAESSAAAAAINVVQLISGA
HCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
FGAGLAGVVVNTAKGGEVAAARGLYMAFTVLAAAGVIASYQATHRDRRLPR
HCCCHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TETASETGSWRQLLSRYLGTSIVLAGGVALYATNEFLTISLLPSTIADIGGSRLYAWVT
CCCCCCCCHHHHHHHHHHCCHHHHHCCEEEEEECCEEEEEECHHHHHHCCCCHHHHHHH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HCCCHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]