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The map label for this gene is lgt

Identifier: 121637521

GI number: 121637521

Start: 1818418

End: 1819824

Strand: Direct

Name: lgt

Synonym: BCG_1652

Alternate gene names: 121637521

Gene position: 1818418-1819824 (Clockwise)

Preceding gene: 121637520

Following gene: 121637522

Centisome position: 41.57

GC content: 64.39

Gene sequence:

>1407_bases
ATGCGGATGTTGCCCAGCTATATCCCCAGCCCACCGCGCGGGGTTTGGTACCTGGGCCCGCTACCCGTCCGCGCCTACGC
AGTTTGCGTTATCACCGGCATCATTGTCGCACTGCTGATCGGGGATCGCCGGTTGACAGCCCGCGGCGGCGAGCGCGGCA
TGACCTACGACATCGCCTTGTGGGCCGTGCCTTTCGGCCTGATTGGCGGCAGGCTCTATCACCTGGCTACCGACTGGCGG
ACATATTTCGGTGACGGTGGTGCCGGGCTGGCCGCGGCACTGCGAATCTGGGATGGGGGCCTGGGCATCTGGGGTGCGGT
AACCCTTGGTGTCATGGGCGCGTGGATTGGCTGCCGGCGTTGTGGAATCCCGCTGCCCGTCTTGCTTGATGCGGTGGCGC
CTGGTGTCGTGTTGGCGCAGGCTATCGGTCGGCTCGGAAACTACTTCAATCAAGAGCTCTACGGCCGGGAAACCACTATG
CCGTGGGGTTTGGAGATCTTCTACCGCCGGGACCCCTCCGGATTCGACGTCCCGAATTCGCTGGACGGCGTCTCGACGGG
TCAGGTGGCGTTCGTCGTGCAGCCAACGTTCCTCTACGAATTGATCTGGAATGTTTTGGTATTCGTCGCATTGATCTACA
TTGACCGCCGGTTCATCATCGGCCACGGGCGACTGTTTGGGTTCTATGTCGCTTTCTACTGCGCCGGGCGATTCTGTGTT
GAGCTGCTGCGTGACGATCCCGCCACGCTTATTGCCGGCATCCGGATCAATTCGTTCACGTCCACCTTCGTGTTTATCGG
GGCCGTGGTGTACATCATCTTGGCGCCGAAGGGGCGCGAGGCTCCTGGGGCCCTGCGTGGCAGCGAGTATGTTGTTGATG
AGGCGCTGGAACGTGAACCGGCTGAACTCGCCGCCGCTGCTGTGGCCTCCGCTGCGAGCGCTGTGGGGCCGGTTGGCCCG
GGGGAACCGAACCAACCCGACGATGTGGCGGAAGCGGTGAAAGCCGAAGTCGCCGAGGTCACCGATGAAGTGGCCGCGGA
ATCCGTTGTCCAAGTAGCAGACCGGGATGGTGAGTCAACCCCCGCTGTCGAGGAGACCTCCGAAGCCGATATCGAGCGGG
AACAACCGGGCGACCTCGCGGGCCAGGCGCCAGCCGCGCACCAGGTCGACGCCGAAGCTGCATCGGCCGCGCCCGAGGAG
CCGGCAGCGTTGGCTTCGGAGGCACACGACGAAACCGAGCCCGAGGTGCCCGAGAAGGCGGCGCCCATCCCCGATCCGGC
CAAGCCGGATGAATTGGCGGTCGCCGGACCTGGGGACGACCCTGCTGAGCCGGACGGCATTCGACGGCAAGACGATTTCA
GCTCGAGACGCCGCCGTTGGTGGCGGCTTCGACGGCGTCGACAATGA

Upstream 100 bases:

>100_bases
TTGGTTCCGCATTGGTGACGGCGCTAACCGAGGGGTTGCCTAGATTGCGGGCACTGACCGGAGAGCTCGCTGCCGGGGTA
CGACTAGGGATGTCCGCATG

Downstream 100 bases:

>100_bases
CGACCCACGACGGCACTGCCTGGTCGCCGGTGCTGGACTCAATAGACCGCCGATCGGGCGGCCGTTGCCGCAGCCGGAAC
GATGCGCCGACGAAGTTCCC

Product: prolipoprotein diacylglyceryl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MRMLPSYIPSPPRGVWYLGPLPVRAYAVCVITGIIVALLIGDRRLTARGGERGMTYDIALWAVPFGLIGGRLYHLATDWR
TYFGDGGAGLAAALRIWDGGLGIWGAVTLGVMGAWIGCRRCGIPLPVLLDAVAPGVVLAQAIGRLGNYFNQELYGRETTM
PWGLEIFYRRDPSGFDVPNSLDGVSTGQVAFVVQPTFLYELIWNVLVFVALIYIDRRFIIGHGRLFGFYVAFYCAGRFCV
ELLRDDPATLIAGIRINSFTSTFVFIGAVVYIILAPKGREAPGALRGSEYVVDEALEREPAELAAAAVASAASAVGPVGP
GEPNQPDDVAEAVKAEVAEVTDEVAAESVVQVADRDGESTPAVEETSEADIEREQPGDLAGQAPAAHQVDAEAASAAPEE
PAALASEAHDETEPEVPEKAAPIPDPAKPDELAVAGPGDDPAEPDGIRRQDDFSSRRRRWWRLRRRRQ

Sequences:

>Translated_468_residues
MRMLPSYIPSPPRGVWYLGPLPVRAYAVCVITGIIVALLIGDRRLTARGGERGMTYDIALWAVPFGLIGGRLYHLATDWR
TYFGDGGAGLAAALRIWDGGLGIWGAVTLGVMGAWIGCRRCGIPLPVLLDAVAPGVVLAQAIGRLGNYFNQELYGRETTM
PWGLEIFYRRDPSGFDVPNSLDGVSTGQVAFVVQPTFLYELIWNVLVFVALIYIDRRFIIGHGRLFGFYVAFYCAGRFCV
ELLRDDPATLIAGIRINSFTSTFVFIGAVVYIILAPKGREAPGALRGSEYVVDEALEREPAELAAAAVASAASAVGPVGP
GEPNQPDDVAEAVKAEVAEVTDEVAAESVVQVADRDGESTPAVEETSEADIEREQPGDLAGQAPAAHQVDAEAASAAPEE
PAALASEAHDETEPEVPEKAAPIPDPAKPDELAVAGPGDDPAEPDGIRRQDDFSSRRRRWWRLRRRRQ
>Mature_468_residues
MRMLPSYIPSPPRGVWYLGPLPVRAYAVCVITGIIVALLIGDRRLTARGGERGMTYDIALWAVPFGLIGGRLYHLATDWR
TYFGDGGAGLAAALRIWDGGLGIWGAVTLGVMGAWIGCRRCGIPLPVLLDAVAPGVVLAQAIGRLGNYFNQELYGRETTM
PWGLEIFYRRDPSGFDVPNSLDGVSTGQVAFVVQPTFLYELIWNVLVFVALIYIDRRFIIGHGRLFGFYVAFYCAGRFCV
ELLRDDPATLIAGIRINSFTSTFVFIGAVVYIILAPKGREAPGALRGSEYVVDEALEREPAELAAAAVASAASAVGPVGP
GEPNQPDDVAEAVKAEVAEVTDEVAAESVVQVADRDGESTPAVEETSEADIEREQPGDLAGQAPAAHQVDAEAASAAPEE
PAALASEAHDETEPEVPEKAAPIPDPAKPDELAVAGPGDDPAEPDGIRRQDDFSSRRRRWWRLRRRRQ

Specific function: Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins

COG id: COG0682

COG function: function code M; Prolipoprotein diacylglyceryltransferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lgt family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LGT_MYCBO (Q7VEW5)

Other databases:

- EMBL:   BX248339
- RefSeq:   NP_855293.1
- EnsemblBacteria:   EBMYCT00000017730
- GeneID:   1092574
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb1640
- GeneTree:   EBGT00050000014973
- HOGENOM:   HBG450278
- OMA:   GRTWIEN
- ProtClustDB:   PRK13108
- BioCyc:   MBOV233413:MB1640-MONOMER
- HAMAP:   MF_01147
- InterPro:   IPR001640
- TIGRFAMs:   TIGR00544

Pfam domain/function: PF01790 LGT

EC number: 2.4.99.- [C]

Molecular weight: Translated: 50393; Mature: 50393

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS01311 LGT

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x15f90eb4)-; HASH(0x160cb4c8)-; HASH(0x15becd80)-; HASH(0x151bf644)-; HASH(0x15f4cdb0)-; HASH(0x161db98c)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMLPSYIPSPPRGVWYLGPLPVRAYAVCVITGIIVALLIGDRRLTARGGERGMTYDIAL
CCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEHHH
WAVPFGLIGGRLYHLATDWRTYFGDGGAGLAAALRIWDGGLGIWGAVTLGVMGAWIGCRR
HHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
CGIPLPVLLDAVAPGVVLAQAIGRLGNYFNQELYGRETTMPWGLEIFYRRDPSGFDVPNS
CCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCC
LDGVSTGQVAFVVQPTFLYELIWNVLVFVALIYIDRRFIIGHGRLFGFYVAFYCAGRFCV
CCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCHHEEECCHHHHHHHHHHHHHHHHH
ELLRDDPATLIAGIRINSFTSTFVFIGAVVYIILAPKGREAPGALRGSEYVVDEALEREP
HHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCH
AELAAAAVASAASAVGPVGPGEPNQPDDVAEAVKAEVAEVTDEVAAESVVQVADRDGEST
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PAVEETSEADIEREQPGDLAGQAPAAHQVDAEAASAAPEEPAALASEAHDETEPEVPEKA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHHHCCCCCHHHHHHHCCCCCCCCCCCCC
APIPDPAKPDELAVAGPGDDPAEPDGIRRQDDFSSRRRRWWRLRRRRQ
CCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MRMLPSYIPSPPRGVWYLGPLPVRAYAVCVITGIIVALLIGDRRLTARGGERGMTYDIAL
CCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEHHH
WAVPFGLIGGRLYHLATDWRTYFGDGGAGLAAALRIWDGGLGIWGAVTLGVMGAWIGCRR
HHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
CGIPLPVLLDAVAPGVVLAQAIGRLGNYFNQELYGRETTMPWGLEIFYRRDPSGFDVPNS
CCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCC
LDGVSTGQVAFVVQPTFLYELIWNVLVFVALIYIDRRFIIGHGRLFGFYVAFYCAGRFCV
CCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCHHEEECCHHHHHHHHHHHHHHHHH
ELLRDDPATLIAGIRINSFTSTFVFIGAVVYIILAPKGREAPGALRGSEYVVDEALEREP
HHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCH
AELAAAAVASAASAVGPVGPGEPNQPDDVAEAVKAEVAEVTDEVAAESVVQVADRDGEST
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PAVEETSEADIEREQPGDLAGQAPAAHQVDAEAASAAPEEPAALASEAHDETEPEVPEKA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHHHCCCCCHHHHHHHCCCCCCCCCCCCC
APIPDPAKPDELAVAGPGDDPAEPDGIRRQDDFSSRRRRWWRLRRRRQ
CCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972