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The map label for this gene is chaA [C]

Identifier: 121637514

GI number: 121637514

Start: 1811428

End: 1812510

Strand: Direct

Name: chaA [C]

Synonym: BCG_1645

Alternate gene names: 121637514

Gene position: 1811428-1812510 (Clockwise)

Preceding gene: 121637513

Following gene: 121637516

Centisome position: 41.41

GC content: 66.48

Gene sequence:

>1083_bases
ATGCTGAAACGAGTGCCCTGGACCGTTGTGCTGCCTTCGCTGGCCTTTGTCGCGCTGGTATTGACCTGGGGAAAGCAGAT
CGGCCCGGTGGTGGGCTTGCTAGCGGCGGTGCTGTTAGCCGGTGCTGTCCTGGCCGCGGTCAACCATGCCGAGGTGGTGG
CGGCCCGGGTGGGTGAGCCATTCGGTTCGCTGGTGCTCGCGGTCGCGGTGACGACCATCGAGGTGGCGCTGATCGTTGCG
CTCATGGTGTCCGGCGGGGACGATGCGGCGACGCTCGCCCGCGACACCGTGTTCGCCGCGGTGATGATCACCACCAACGG
GATCGCCGGGTTGTCCCTGCTGCTGGGTTCGCTGCGCTATGGCGTGACGTTGTTCAACCCCCACGGCAGCGGCGCCGCGC
TGGCCACGGTCACCACACTGGCGACGCTGAGCCTGGTGCTGCCCACGTTCACCACCAGTCAGTCGGGCCCCGAGCTATCG
CCCGGCCAGCTCATCTTCGCCGGCGCCGCGTCGCTGGGACTCTACGTGTTGTTCCTGTTCACCCAGACTGTCCGGCATCG
AGACTTCTTCCTACCGGTGGCGCAAAAGGGCGCGGTCGAGGATGACAGCCACGCCGATCCACCGAGCACCCGCGCGGCGC
TGCTGAGCCTTGGATTGCTGCTCGTCGCTTTGGTTGCGGTGGTGGGTCTGGCCAAGGTGGAATCGCCGGTCATCGAGGAG
GTCGTCTCGGCGGCCGGGTTTCCGCAATCCTTCGTCGGCGTGGTCATCGCCACACTGGTGCTGTTGCCGGAGACACTTGC
GGCGGCCCGCGCGGCCCGGCAAGGCCGCCTGCAGACCAGCCTCAATCTGGCGTACGGTTCCGCGATGGCGAGTATTGGAC
TCACCATCCCGACCATCGCCCTTGCTTCCCTGTGGCTCAGTGGCCCGCTGCAACTTGGCCTCGGTGCCATTCAGTTGGTG
CTGCTGGTGCTCACGGTTGTGGTCAGCGTGCTGACCGTGGTTCCCGGTCGGGCCACCCGTCTGCAGGGCGAGGTGCATCT
GGTGTTGCTGGCTGCTTACCTGTTTCTTGCCGTCGTCCCGTGA

Upstream 100 bases:

>100_bases
ACACGCCGCCGAGCGAGCGCGGACATACCACCTTGGGATCCATGCAGATGTCAAGGGGGGTTGCCCGTCCGGGCGATGGC
GTCGATGAGAATGGCGGTCG

Downstream 100 bases:

>100_bases
TGAATCCGTGCGCAAGCGATGGTTTTCGCCGCCGCTATCCAGATCTGATTGCCCGCAGCGTCGCTAACGCTTTGTCGGCG
TGGGCGTCCATGCTGAATTC

Product: putative ionic transporter integral membrane protein chaA

Products: Na (I) [Periplasm]; Ca (II) [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MLKRVPWTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLVLAVAVTTIEVALIVA
LMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELS
PGQLIFAGAASLGLYVLFLFTQTVRHRDFFLPVAQKGAVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEE
VVSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALASLWLSGPLQLGLGAIQLV
LLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP

Sequences:

>Translated_360_residues
MLKRVPWTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLVLAVAVTTIEVALIVA
LMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELS
PGQLIFAGAASLGLYVLFLFTQTVRHRDFFLPVAQKGAVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEE
VVSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALASLWLSGPLQLGLGAIQLV
LLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP
>Mature_360_residues
MLKRVPWTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLVLAVAVTTIEVALIVA
LMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELS
PGQLIFAGAASLGLYVLFLFTQTVRHRDFFLPVAQKGAVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEE
VVSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALASLWLSGPLQLGLGAIQLV
LLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP

Specific function: Possible cation transporter [H]

COG id: COG0387

COG function: function code P; Ca2+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Escherichia coli, GI1787468, Length=351, Percent_Identity=35.8974358974359, Blast_Score=193, Evalue=2e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004713
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 36772; Mature: 36772

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRVPWTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FGSLVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRY
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHH
GVTLFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLF
CEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHH
TQTVRHRDFFLPVAQKGAVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEE
HHHHHHHHHCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VVSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIA
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHH
LASLWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLKRVPWTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FGSLVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRY
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHH
GVTLFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLF
CEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHH
TQTVRHRDFFLPVAQKGAVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEE
HHHHHHHHHCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VVSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIA
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHH
LASLWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Cytoplasm]; Proton [Periplasm]; Ca (II) [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: Na (I) [Cytoplasm] + Proton [Periplasm] = Proton [Cytoplasm] + Na (I) [Periplasm] Ca (II) [Cytoplasm] + Proton [Periplasm] = Ca (II) [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]