Click here to switch to the map view.

The map label for this gene is iap [H]

Identifier: 121637409

GI number: 121637409

Start: 1693491

End: 1694216

Strand: Direct

Name: iap [H]

Synonym: BCG_1540

Alternate gene names: 121637409

Gene position: 1693491-1694216 (Clockwise)

Preceding gene: 121637408

Following gene: 121637410

Centisome position: 38.71

GC content: 67.22

Gene sequence:

>726_bases
ATGCGCCACACGCGTTTTCACCCGATCAAACTGGCCTGGATCACCGCGGTGGTTGCCGGCCTGATGGTCGGTGTGGCAAC
GCCCGCCGATGCCGAACCCGGACAATGGGATCCCACGCTGCCGGCATTGGTCAGTGCGGGGGCGCCCGGAGATCCGCTGG
CGGTAGCCAACGCGTCGTTGCAGGCCACCGCCCAGGCCACCCAGACCACGCTGGATTTGGGCAGGCAGTTCCTCGGTGGG
TTGGGAATCAACCTCGGCGGCCCTGCTGCCAGCGCTCCCAGCGCCGCCACAACCGGCGCGAGCCGGATTCCGCGGGCCAA
CGCCCGTCAGGCCGTCGAATATGTGATTCGCCGGGCCGGGTCGCAGATGGGGGTGCCCTATTCGTGGGGTGGTGGCTCGC
TTCAGGGCCCCAGCAAGGGCGTGGACTCGGGGGCCAACACTGTCGGCTTCGACTGCTCAGGTCTGGTGCGGTATGCCTTC
GCCGGGGTCGGCGTGCTGATCCCGCGGTTCTCCGGTGATCAGTACAACGCCGGTCGCCACGTTCCGCCCGCTGAGGCCAA
GCGCGGCGACCTGATCTTTTACGGCCCAGGCGGCGGCCAGCACGTCACCCTGTATCTGGGCAACGGCCAAATGCTGGAGG
CATCCGGAAGCGCCGGCAAAGTCACGGTGAGCCCGGTGCGAAAGGCCGGAATGACGCCGTTCGTGACTAGGATCATCGAA
TACTGA

Upstream 100 bases:

>100_bases
GAGGCGCCCGACGTCGGTTTGAAGGTGCGGGTTGCGCCCGTGCGCACGGCTGGCATGACCCCGTATGTGGTCCGATACAT
CGAGTACTAGACGAGGATTC

Downstream 100 bases:

>100_bases
GCCAGGTGTGATTTGCCGGGCACCACCGCGGCGTCGACGGAATCCAGGAGGCCTGGAATAGTTGAACGCGGGCGCGTCGC
TGCCCCGCGACGTTGGTCAT

Product: invasion protein

Products: NA

Alternate protein names: Invasion-associated protein [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MRHTRFHPIKLAWITAVVAGLMVGVATPADAEPGQWDPTLPALVSAGAPGDPLAVANASLQATAQATQTTLDLGRQFLGG
LGINLGGPAASAPSAATTGASRIPRANARQAVEYVIRRAGSQMGVPYSWGGGSLQGPSKGVDSGANTVGFDCSGLVRYAF
AGVGVLIPRFSGDQYNAGRHVPPAEAKRGDLIFYGPGGGQHVTLYLGNGQMLEASGSAGKVTVSPVRKAGMTPFVTRIIE
Y

Sequences:

>Translated_241_residues
MRHTRFHPIKLAWITAVVAGLMVGVATPADAEPGQWDPTLPALVSAGAPGDPLAVANASLQATAQATQTTLDLGRQFLGG
LGINLGGPAASAPSAATTGASRIPRANARQAVEYVIRRAGSQMGVPYSWGGGSLQGPSKGVDSGANTVGFDCSGLVRYAF
AGVGVLIPRFSGDQYNAGRHVPPAEAKRGDLIFYGPGGGQHVTLYLGNGQMLEASGSAGKVTVSPVRKAGMTPFVTRIIE
Y
>Mature_241_residues
MRHTRFHPIKLAWITAVVAGLMVGVATPADAEPGQWDPTLPALVSAGAPGDPLAVANASLQATAQATQTTLDLGRQFLGG
LGINLGGPAASAPSAATTGASRIPRANARQAVEYVIRRAGSQMGVPYSWGGGSLQGPSKGVDSGANTVGFDCSGLVRYAF
AGVGVLIPRFSGDQYNAGRHVPPAEAKRGDLIFYGPGGGQHVTLYLGNGQMLEASGSAGKVTVSPVRKAGMTPFVTRIIE
Y

Specific function: This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1787944, Length=128, Percent_Identity=31.25, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482
- InterPro:   IPR003646
- InterPro:   IPR013247 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60; PF08239 SH3_3 [H]

EC number: NA

Molecular weight: Translated: 24624; Mature: 24624

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHTRFHPIKLAWITAVVAGLMVGVATPADAEPGQWDPTLPALVSAGAPGDPLAVANASL
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEECCCH
QATAQATQTTLDLGRQFLGGLGINLGGPAASAPSAATTGASRIPRANARQAVEYVIRRAG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHCC
SQMGVPYSWGGGSLQGPSKGVDSGANTVGFDCSGLVRYAFAGVGVLIPRFSGDQYNAGRH
CCCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHEEEECCCCCCCCCCCC
VPPAEAKRGDLIFYGPGGGQHVTLYLGNGQMLEASGSAGKVTVSPVRKAGMTPFVTRIIE
CCCCCCCCCCEEEECCCCCCEEEEEECCCEEEECCCCCCEEEECHHHHCCCCHHHHHHHC
Y
C
>Mature Secondary Structure
MRHTRFHPIKLAWITAVVAGLMVGVATPADAEPGQWDPTLPALVSAGAPGDPLAVANASL
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEECCCH
QATAQATQTTLDLGRQFLGGLGINLGGPAASAPSAATTGASRIPRANARQAVEYVIRRAG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHCC
SQMGVPYSWGGGSLQGPSKGVDSGANTVGFDCSGLVRYAFAGVGVLIPRFSGDQYNAGRH
CCCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHEEEECCCCCCCCCCCC
VPPAEAKRGDLIFYGPGGGQHVTLYLGNGQMLEASGSAGKVTVSPVRKAGMTPFVTRIIE
CCCCCCCCCCEEEECCCCCCEEEEEECCCEEEECCCCCCEEEECHHHHCCCCHHHHHHHC
Y
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1514809; 1459966 [H]