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The map label for this gene is iap [H]

Identifier: 121637408

GI number: 121637408

Start: 1692062

End: 1693480

Strand: Direct

Name: iap [H]

Synonym: BCG_1539

Alternate gene names: 121637408

Gene position: 1692062-1693480 (Clockwise)

Preceding gene: 121637407

Following gene: 121637409

Centisome position: 38.68

GC content: 67.02

Gene sequence:

>1419_bases
ATGAGACGGAATCGCCGTGGCTCGCCAGCGCGACCGGCCGCACGGTTTGTCCGTCCGGCAATTCCGTCGGCTTTGAGTGT
GGCCCTGCTGGTATGCACACCGGGGCTGGCTACCGCCGATCCACAGACGGACACCATCGCCGCGCTGATTGCCGACGTCG
CCAAGGCCAACCAGCGCCTGCAAGACCTGAGCGACGAGGTTCAGGCCGAACAGGAAAGCGTTAACAAGGCGATGGTCGAC
GTGGAAACCGCTCGGGACAACGCTGCCGCGGCCGAAGACGACCTGGAGGTCAGCCAGCGCGCGGTTAAGGACGCCAACGC
GGCGATCGCCGCGGCTCAGCACCGGTTCGACACCTTCGCGGCGGCCACCTACATGAACGGTCCCTCGGTCAGCTACCTCA
GCGCGAGCAGCCCCGACGAGATCATTGCCACTGTGACCGCCGCCAAGACCCTTAGCGCCAGTTCCCAAGCGGTGATGGCC
AACCTGCAGCGGGCCCGGACCGAGCGGGTGAACACGGAGTCGGCGGCGCGGCTAGCCAAGCAGAAGGCTGATAAGGCCGC
CGCCGACGCAAAGGCCAGCCAGGATGCCGCGGTGGCGGCGCTCACCGAGACCCGGCGGAAGTTCGATGAACAGCGCGAGG
AGGTCCAACGCCTGGCCGCCGAGCGCGATGCGGCTCAAGCCCGACTGCAGGCGGCCAGGTTGGTTGCCTGGTCCTCGGAG
GGTGGTCAGGGTGCGCCGCCGTTCCGGATGTGGGATCCCGGATCGGGCCCTGCCGGTGGGCGTGCATGGGATGGCTTGTG
GGACCCCACGCTGCCCATGATCCCCAGCGCCAACATCCCCGGCGACCCGATCGCGGTAGTGAACCAGGTGTTGGGGATCT
CGGCAACGTCAGCGCAGGTCACCGCCAATATGGGGCGCAAGTTCCTGGAGCAGCTGGGCATCTTGCAGCCCACCGATACC
GGCATCACCAACGCTCCGGCGGGCTCGGCCCAGGGCCGGATTCCGCGAGTTTATGGGCGCCAGGCTTCTGAATACGTGAT
CCGCCGCGGCATGTCACAGATCGGGGTGCCCTATTCCTGGGGCGGCGGCAATGCCGCGGGCCCGAGCAAGGGCATCGACT
CCGGGGCCGGCACCGTCGGCTTCGACTGCTCAGGCCTGGTGTTGTACTCGTTTGCTGGGGTGGGCATCAAGCTGCCGCAC
TACTCGGGTTCGCAGTACAACCTGGGCCGCAAGATCCCGTCCTCGCAGATGCGCCGCGGCGACGTCATCTTCTACGGCCC
GAACGGTAGCCAGCACGTGACGATCTACCTCGGCAACGGCCAGATGCTCGAGGCGCCCGACGTCGGTTTGAAGGTGCGGG
TTGCGCCCGTGCGCACGGCTGGCATGACCCCGTATGTGGTCCGATACATCGAGTACTAG

Upstream 100 bases:

>100_bases
ATAGCGTCAGATGTGACGTACGGTGCAAATGATGCTTGTGGTGTCGTTGGCGTTGACCTGCGCTGTCCCTCCGAGTTGAG
CCCTAGGAGATCTGAGTCGA

Downstream 100 bases:

>100_bases
ACGAGGATTCATGCGCCACACGCGTTTTCACCCGATCAAACTGGCCTGGATCACCGCGGTGGTTGCCGGCCTGATGGTCG
GTGTGGCAACGCCCGCCGAT

Product: invasion protein

Products: NA

Alternate protein names: Invasion-associated protein [H]

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MRRNRRGSPARPAARFVRPAIPSALSVALLVCTPGLATADPQTDTIAALIADVAKANQRLQDLSDEVQAEQESVNKAMVD
VETARDNAAAAEDDLEVSQRAVKDANAAIAAAQHRFDTFAAATYMNGPSVSYLSASSPDEIIATVTAAKTLSASSQAVMA
NLQRARTERVNTESAARLAKQKADKAAADAKASQDAAVAALTETRRKFDEQREEVQRLAAERDAAQARLQAARLVAWSSE
GGQGAPPFRMWDPGSGPAGGRAWDGLWDPTLPMIPSANIPGDPIAVVNQVLGISATSAQVTANMGRKFLEQLGILQPTDT
GITNAPAGSAQGRIPRVYGRQASEYVIRRGMSQIGVPYSWGGGNAAGPSKGIDSGAGTVGFDCSGLVLYSFAGVGIKLPH
YSGSQYNLGRKIPSSQMRRGDVIFYGPNGSQHVTIYLGNGQMLEAPDVGLKVRVAPVRTAGMTPYVVRYIEY

Sequences:

>Translated_472_residues
MRRNRRGSPARPAARFVRPAIPSALSVALLVCTPGLATADPQTDTIAALIADVAKANQRLQDLSDEVQAEQESVNKAMVD
VETARDNAAAAEDDLEVSQRAVKDANAAIAAAQHRFDTFAAATYMNGPSVSYLSASSPDEIIATVTAAKTLSASSQAVMA
NLQRARTERVNTESAARLAKQKADKAAADAKASQDAAVAALTETRRKFDEQREEVQRLAAERDAAQARLQAARLVAWSSE
GGQGAPPFRMWDPGSGPAGGRAWDGLWDPTLPMIPSANIPGDPIAVVNQVLGISATSAQVTANMGRKFLEQLGILQPTDT
GITNAPAGSAQGRIPRVYGRQASEYVIRRGMSQIGVPYSWGGGNAAGPSKGIDSGAGTVGFDCSGLVLYSFAGVGIKLPH
YSGSQYNLGRKIPSSQMRRGDVIFYGPNGSQHVTIYLGNGQMLEAPDVGLKVRVAPVRTAGMTPYVVRYIEY
>Mature_472_residues
MRRNRRGSPARPAARFVRPAIPSALSVALLVCTPGLATADPQTDTIAALIADVAKANQRLQDLSDEVQAEQESVNKAMVD
VETARDNAAAAEDDLEVSQRAVKDANAAIAAAQHRFDTFAAATYMNGPSVSYLSASSPDEIIATVTAAKTLSASSQAVMA
NLQRARTERVNTESAARLAKQKADKAAADAKASQDAAVAALTETRRKFDEQREEVQRLAAERDAAQARLQAARLVAWSSE
GGQGAPPFRMWDPGSGPAGGRAWDGLWDPTLPMIPSANIPGDPIAVVNQVLGISATSAQVTANMGRKFLEQLGILQPTDT
GITNAPAGSAQGRIPRVYGRQASEYVIRRGMSQIGVPYSWGGGNAAGPSKGIDSGAGTVGFDCSGLVLYSFAGVGIKLPH
YSGSQYNLGRKIPSSQMRRGDVIFYGPNGSQHVTIYLGNGQMLEAPDVGLKVRVAPVRTAGMTPYVVRYIEY

Specific function: This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1787944, Length=124, Percent_Identity=30.6451612903226, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786421, Length=119, Percent_Identity=34.453781512605, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482
- InterPro:   IPR003646
- InterPro:   IPR013247 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60; PF08239 SH3_3 [H]

EC number: NA

Molecular weight: Translated: 49808; Mature: 49808

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRNRRGSPARPAARFVRPAIPSALSVALLVCTPGLATADPQTDTIAALIADVAKANQRL
CCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
QDLSDEVQAEQESVNKAMVDVETARDNAAAAEDDLEVSQRAVKDANAAIAAAQHRFDTFA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AATYMNGPSVSYLSASSPDEIIATVTAAKTLSASSQAVMANLQRARTERVNTESAARLAK
HHHCCCCCCEEEECCCCCHHHEEHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHH
QKADKAAADAKASQDAAVAALTETRRKFDEQREEVQRLAAERDAAQARLQAARLVAWSSE
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
GGQGAPPFRMWDPGSGPAGGRAWDGLWDPTLPMIPSANIPGDPIAVVNQVLGISATSAQV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHH
TANMGRKFLEQLGILQPTDTGITNAPAGSAQGRIPRVYGRQASEYVIRRGMSQIGVPYSW
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHCCHHHHCCCEEC
GGGNAAGPSKGIDSGAGTVGFDCSGLVLYSFAGVGIKLPHYSGSQYNLGRKIPSSQMRRG
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEECCCCCCCCCCCCCCCCHHHHCCC
DVIFYGPNGSQHVTIYLGNGQMLEAPDVGLKVRVAPVRTAGMTPYVVRYIEY
CEEEECCCCCCEEEEEECCCEEEECCCCCEEEEEEECCCCCCCHHHHHEECC
>Mature Secondary Structure
MRRNRRGSPARPAARFVRPAIPSALSVALLVCTPGLATADPQTDTIAALIADVAKANQRL
CCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
QDLSDEVQAEQESVNKAMVDVETARDNAAAAEDDLEVSQRAVKDANAAIAAAQHRFDTFA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AATYMNGPSVSYLSASSPDEIIATVTAAKTLSASSQAVMANLQRARTERVNTESAARLAK
HHHCCCCCCEEEECCCCCHHHEEHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHH
QKADKAAADAKASQDAAVAALTETRRKFDEQREEVQRLAAERDAAQARLQAARLVAWSSE
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
GGQGAPPFRMWDPGSGPAGGRAWDGLWDPTLPMIPSANIPGDPIAVVNQVLGISATSAQV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHH
TANMGRKFLEQLGILQPTDTGITNAPAGSAQGRIPRVYGRQASEYVIRRGMSQIGVPYSW
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHCCHHHHCCCEEC
GGGNAAGPSKGIDSGAGTVGFDCSGLVLYSFAGVGIKLPHYSGSQYNLGRKIPSSQMRRG
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEECCCCCCCCCCCCCCCCHHHHCCC
DVIFYGPNGSQHVTIYLGNGQMLEAPDVGLKVRVAPVRTAGMTPYVVRYIEY
CEEEECCCCCCEEEEEECCCEEEECCCCCEEEEEEECCCCCCCHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1514809; 1459966 [H]