Click here to switch to the map view.

The map label for this gene is gap [H]

Identifier: 121637366

GI number: 121637366

Start: 1638115

End: 1639134

Strand: Direct

Name: gap [H]

Synonym: BCG_1497

Alternate gene names: 121637366

Gene position: 1638115-1639134 (Clockwise)

Preceding gene: 121637364

Following gene: 121637367

Centisome position: 37.45

GC content: 63.14

Gene sequence:

>1020_bases
GTGACGGTCCGAGTAGGCATCAACGGGTTTGGTCGAATCGGACGCAACTTCTACCGGGCCTTACTGGCCCAACAGGAGCA
GGGCACCGCCGACGTGGAGGTGGTCGCCGCCAACGACATCACCGACAACAGCACGCTGGCGCATCTGCTCAAATTCGACT
CGATTCTGGGCCGGCTGCCTTGCGATGTCGGCCTCGAAGGCGACGACACCATCGTCGTCGGCCGCGCGAAAATCAAGGCG
CTCGCGGTCCGGGAGGGGCCGGCGGCATTGCCATGGGGAGACCTCGGCGTCGACGTCGTCGTCGAATCCACCGGCCTGTT
CACCAATGCGGCCAAAGCCAAAGGCCACCTGGACGCCGGCGCCAAGAAGGTGATCATCTCTGCGCCCGCCACCGACGAGG
ACATCACCATCGTCCTGGGAGTTAACGACGACAAGTATGACGGCAGCCAGAACATCATCTCCAATGCGTCGTGCACCACG
AACTGCCTTGCGCCGCTGGCCAAAGTGCTCGACGATGAGTTCGGCATCGTCAAGGGCCTGATGACCACCATCCACGCCTA
CACTCAGGATCAGAACCTGCAGGACGGGCCGCACAAGGACCTGCGTCGCGCCCGCGCCGCCGCGCTGAACATCGTGCCGA
CCTCCACCGGCGCGGCCAAGGCCATCGGCCTGGTGATGCCGCAGCTAAAGGGCAAGCTCGACGGTTATGCGCTGCGGGTG
CCGATCCCCACCGGCTCGGTCACCGACCTTACGGTCGACTTATCCACACGGGCCAGTGTCGATGAGATCAACGCGGCGTT
CAAAGCCGCGGCCGAAGGCAGGCTCAAGGGCATTCTGAAGTACTACGACGCGCCGATCGTCTCGAGCGACATCGTCACCG
ACCCGCACAGTTCGATTTTCGACTCTGGGTTGACCAAAGTCATCGACGACCAGGCCAAGGTGGTGTCGTGGTACGACAAC
GAGTGGGGCTACTCCAACCGCCTGGTTGATCTGGTCACGCTGGTCGGCAAGTCGCTCTAG

Upstream 100 bases:

>100_bases
ACTCTTACCGGCCGAAGGCGGCGGGTGTCACTGATCTAGGCTGACGGCCAGTGGTTGTTTAGCCAACAAGGATGACAACA
AATAAGCCGAGGAGAGACAA

Downstream 100 bases:

>100_bases
CCATGAGCGTTGCAAACCTCAAGGATCTACTCGCCGAAGGTGTTTCGGGGCGTGGAGTGCTGGTGCGCTCCGATCTCAAC
GTTCCGCTCGACGAGGACGG

Product: putative glyceraldehyde 3-phosphate dehydrogenase gap

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MTVRVGINGFGRIGRNFYRALLAQQEQGTADVEVVAANDITDNSTLAHLLKFDSILGRLPCDVGLEGDDTIVVGRAKIKA
LAVREGPAALPWGDLGVDVVVESTGLFTNAAKAKGHLDAGAKKVIISAPATDEDITIVLGVNDDKYDGSQNIISNASCTT
NCLAPLAKVLDDEFGIVKGLMTTIHAYTQDQNLQDGPHKDLRRARAAALNIVPTSTGAAKAIGLVMPQLKGKLDGYALRV
PIPTGSVTDLTVDLSTRASVDEINAAFKAAAEGRLKGILKYYDAPIVSSDIVTDPHSSIFDSGLTKVIDDQAKVVSWYDN
EWGYSNRLVDLVTLVGKSL

Sequences:

>Translated_339_residues
MTVRVGINGFGRIGRNFYRALLAQQEQGTADVEVVAANDITDNSTLAHLLKFDSILGRLPCDVGLEGDDTIVVGRAKIKA
LAVREGPAALPWGDLGVDVVVESTGLFTNAAKAKGHLDAGAKKVIISAPATDEDITIVLGVNDDKYDGSQNIISNASCTT
NCLAPLAKVLDDEFGIVKGLMTTIHAYTQDQNLQDGPHKDLRRARAAALNIVPTSTGAAKAIGLVMPQLKGKLDGYALRV
PIPTGSVTDLTVDLSTRASVDEINAAFKAAAEGRLKGILKYYDAPIVSSDIVTDPHSSIFDSGLTKVIDDQAKVVSWYDN
EWGYSNRLVDLVTLVGKSL
>Mature_338_residues
TVRVGINGFGRIGRNFYRALLAQQEQGTADVEVVAANDITDNSTLAHLLKFDSILGRLPCDVGLEGDDTIVVGRAKIKAL
AVREGPAALPWGDLGVDVVVESTGLFTNAAKAKGHLDAGAKKVIISAPATDEDITIVLGVNDDKYDGSQNIISNASCTTN
CLAPLAKVLDDEFGIVKGLMTTIHAYTQDQNLQDGPHKDLRRARAAALNIVPTSTGAAKAIGLVMPQLKGKLDGYALRVP
IPTGSVTDLTVDLSTRASVDEINAAFKAAAEGRLKGILKYYDAPIVSSDIVTDPHSSIFDSGLTKVIDDQAKVVSWYDNE
WGYSNRLVDLVTLVGKSL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=333, Percent_Identity=50.7507507507508, Blast_Score=306, Evalue=2e-83,
Organism=Homo sapiens, GI7657116, Length=332, Percent_Identity=49.3975903614458, Blast_Score=293, Evalue=1e-79,
Organism=Escherichia coli, GI1788079, Length=339, Percent_Identity=51.622418879056, Blast_Score=328, Evalue=2e-91,
Organism=Escherichia coli, GI1789295, Length=332, Percent_Identity=43.6746987951807, Blast_Score=273, Evalue=9e-75,
Organism=Caenorhabditis elegans, GI17534679, Length=339, Percent_Identity=53.0973451327434, Blast_Score=318, Evalue=2e-87,
Organism=Caenorhabditis elegans, GI17534677, Length=339, Percent_Identity=52.8023598820059, Blast_Score=317, Evalue=4e-87,
Organism=Caenorhabditis elegans, GI32566163, Length=339, Percent_Identity=52.212389380531, Blast_Score=313, Evalue=1e-85,
Organism=Caenorhabditis elegans, GI17568413, Length=339, Percent_Identity=52.212389380531, Blast_Score=312, Evalue=1e-85,
Organism=Saccharomyces cerevisiae, GI6321631, Length=339, Percent_Identity=51.9174041297935, Blast_Score=317, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6322468, Length=339, Percent_Identity=51.0324483775811, Blast_Score=315, Evalue=7e-87,
Organism=Saccharomyces cerevisiae, GI6322409, Length=339, Percent_Identity=50.7374631268437, Blast_Score=315, Evalue=9e-87,
Organism=Drosophila melanogaster, GI17933600, Length=332, Percent_Identity=52.1084337349398, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI18110149, Length=332, Percent_Identity=52.1084337349398, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI85725000, Length=332, Percent_Identity=51.5060240963855, Blast_Score=304, Evalue=5e-83,
Organism=Drosophila melanogaster, GI22023983, Length=332, Percent_Identity=51.5060240963855, Blast_Score=304, Evalue=5e-83,
Organism=Drosophila melanogaster, GI19922412, Length=331, Percent_Identity=48.6404833836858, Blast_Score=291, Evalue=6e-79,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35956; Mature: 35825

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRVGINGFGRIGRNFYRALLAQQEQGTADVEVVAANDITDNSTLAHLLKFDSILGRLP
CEEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCC
CDVGLEGDDTIVVGRAKIKALAVREGPAALPWGDLGVDVVVESTGLFTNAAKAKGHLDAG
CCCCCCCCCEEEEECCEEEEEEEECCCCCCCCCCCCEEEEEECCCCEECCHHCCCCCCCC
AKKVIISAPATDEDITIVLGVNDDKYDGSQNIISNASCTTNCLAPLAKVLDDEFGIVKGL
CCEEEEECCCCCCCEEEEEECCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCHHHHHHHH
MTTIHAYTQDQNLQDGPHKDLRRARAAALNIVPTSTGAAKAIGLVMPQLKGKLDGYALRV
HHHHHHHHCCCCCCCCCHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEE
PIPTGSVTDLTVDLSTRASVDEINAAFKAAAEGRLKGILKYYDAPIVSSDIVTDPHSSIF
ECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
DSGLTKVIDDQAKVVSWYDNEWGYSNRLVDLVTLVGKSL
HHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TVRVGINGFGRIGRNFYRALLAQQEQGTADVEVVAANDITDNSTLAHLLKFDSILGRLP
EEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCC
CDVGLEGDDTIVVGRAKIKALAVREGPAALPWGDLGVDVVVESTGLFTNAAKAKGHLDAG
CCCCCCCCCEEEEECCEEEEEEEECCCCCCCCCCCCEEEEEECCCCEECCHHCCCCCCCC
AKKVIISAPATDEDITIVLGVNDDKYDGSQNIISNASCTTNCLAPLAKVLDDEFGIVKGL
CCEEEEECCCCCCCEEEEEECCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCHHHHHHHH
MTTIHAYTQDQNLQDGPHKDLRRARAAALNIVPTSTGAAKAIGLVMPQLKGKLDGYALRV
HHHHHHHHCCCCCCCCCHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEE
PIPTGSVTDLTVDLSTRASVDEINAAFKAAAEGRLKGILKYYDAPIVSSDIVTDPHSSIF
ECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
DSGLTKVIDDQAKVVSWYDNEWGYSNRLVDLVTLVGKSL
HHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10702355 [H]