Definition Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome.
Accession NC_008769
Length 4,374,522

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The map label for this gene is 121637291

Identifier: 121637291

GI number: 121637291

Start: 1557862

End: 1558884

Strand: Direct

Name: 121637291

Synonym: BCG_1422

Alternate gene names: NA

Gene position: 1557862-1558884 (Clockwise)

Preceding gene: 121637290

Following gene: 121637297

Centisome position: 35.61

GC content: 63.64

Gene sequence:

>1023_bases
ATGGGTGGTGCCCGCCGGCTCAAGCTCGACGGGAGCATCCCCAACCAGCTCGCCCGGGCGGCCGACGCGGCCGTCGCACT
TGAGCGCAATGGTTTCGATGGGGGCTGGACAGCTGAAGCCAGCCATGATCCCTTTCTCCCGCTGCTACTGGCTGCCGAGC
ACACGTCGCGACTTGAGCTTGGCACCAACATCGCGGTAGCGTTCGCGCGCAATCCGATGATTGTCGCCAACGTGGGCTGG
GACCTACAGACGTACTCGAAGGGAAGATTGATCCTCGGTCTGGGAACCCAGATCCGGCCGCACATCGAGAAACGATTCAG
CATGCCCTGGGGTCATCCGGCACGTCGGATGCGTGAATTCGTCGCCGCGCTGCGTGCGATCTGGTTGGCTTGGCAGGACG
GGACCAAGCTTTGCTTCGAGGGTGAGTTCTACACCCACAAGATCATGACCCCGATGTTCACACCCGAGCCGCAGCCCTAT
CCCGTTCCGAGAGTCTTCATCGCCGCTGTCGGTGAAGCGATGACCGAAATGTGCGGCGAAGTCGCCGACGGCCACCTCGG
TCACCCTATGGTCTCGAAACGGTACCTCACCGAGGTGTCGGTGCCGGCGCTGCTACGTGGCCTGGCGCGATCGGGTCGCG
ATCGCAGTGCCTTCGAGGTGTCGTGCGAGGTGATGGTGGCCACTGGCGCGGACGACGCCGAACTGGCGGCCGCCTGCACT
GCCACGCGCAAGCAAATCGCCTTCTACGGATCCACGCCGGCTTACCGCAAAGTCCTCGAGCAGCATGGCTGGGGCGATCT
GCACCCGGAGCTGCACCGCCTCTCCAAGCTGGGTGAGTGGGAGGCCATGGGTGGGCTAATCGACGACGAGATGCTCGGTG
CTTTCGCGGTGGTCGGTCCGGTGGACACGATCGCCGGTGCCCTTCGCAATCGTTGTGAGGGCGTCGTCGACCGCGTCTTG
CCGATTTTCATGGCCGCATCTCAGGAGTGTATTAACGCCGCACTGCAGGACTTTCGCCGTTGA

Upstream 100 bases:

>100_bases
TATGTCGTCGGCTGCCCAGCGCGCAATGTGTGGCACGGCGAGTTGATGTTCAACCTCGGCGTGTCCTGCATACTGGATTT
CTTACTGTAAAGTCACCCAA

Downstream 100 bases:

>100_bases
GCGCGCCATCGGTGGATGAGGCCACCAAGATCGCTGCCCGCATAGAGGGCCCGCATTGCGTGCGGATCGGCGTTACCCGG
CGGCGGGCACACGGGGCATT

Product: putative oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MGGARRLKLDGSIPNQLARAADAAVALERNGFDGGWTAEASHDPFLPLLLAAEHTSRLELGTNIAVAFARNPMIVANVGW
DLQTYSKGRLILGLGTQIRPHIEKRFSMPWGHPARRMREFVAALRAIWLAWQDGTKLCFEGEFYTHKIMTPMFTPEPQPY
PVPRVFIAAVGEAMTEMCGEVADGHLGHPMVSKRYLTEVSVPALLRGLARSGRDRSAFEVSCEVMVATGADDAELAAACT
ATRKQIAFYGSTPAYRKVLEQHGWGDLHPELHRLSKLGEWEAMGGLIDDEMLGAFAVVGPVDTIAGALRNRCEGVVDRVL
PIFMAASQECINAALQDFRR

Sequences:

>Translated_340_residues
MGGARRLKLDGSIPNQLARAADAAVALERNGFDGGWTAEASHDPFLPLLLAAEHTSRLELGTNIAVAFARNPMIVANVGW
DLQTYSKGRLILGLGTQIRPHIEKRFSMPWGHPARRMREFVAALRAIWLAWQDGTKLCFEGEFYTHKIMTPMFTPEPQPY
PVPRVFIAAVGEAMTEMCGEVADGHLGHPMVSKRYLTEVSVPALLRGLARSGRDRSAFEVSCEVMVATGADDAELAAACT
ATRKQIAFYGSTPAYRKVLEQHGWGDLHPELHRLSKLGEWEAMGGLIDDEMLGAFAVVGPVDTIAGALRNRCEGVVDRVL
PIFMAASQECINAALQDFRR
>Mature_339_residues
GGARRLKLDGSIPNQLARAADAAVALERNGFDGGWTAEASHDPFLPLLLAAEHTSRLELGTNIAVAFARNPMIVANVGWD
LQTYSKGRLILGLGTQIRPHIEKRFSMPWGHPARRMREFVAALRAIWLAWQDGTKLCFEGEFYTHKIMTPMFTPEPQPYP
VPRVFIAAVGEAMTEMCGEVADGHLGHPMVSKRYLTEVSVPALLRGLARSGRDRSAFEVSCEVMVATGADDAELAAACTA
TRKQIAFYGSTPAYRKVLEQHGWGDLHPELHRLSKLGEWEAMGGLIDDEMLGAFAVVGPVDTIAGALRNRCEGVVDRVLP
IFMAASQECINAALQDFRR

Specific function: Unknown

COG id: COG2141

COG function: function code C; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1360_MYCTU (P64831)

Other databases:

- EMBL:   BX842576
- EMBL:   AE000516
- PIR:   G70741
- RefSeq:   NP_215876.1
- RefSeq:   NP_335854.1
- ProteinModelPortal:   P64831
- EnsemblBacteria:   EBMYCT00000002710
- EnsemblBacteria:   EBMYCT00000069644
- GeneID:   886813
- GeneID:   924507
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1405
- KEGG:   mtu:Rv1360
- TIGR:   MT1405
- TubercuList:   Rv1360
- GeneTree:   EBGT00050000014764
- HOGENOM:   HBG569343
- OMA:   RYVREVT
- ProtClustDB:   CLSK791121
- InterPro:   IPR019919
- InterPro:   IPR011251
- InterPro:   IPR016048
- Gene3D:   G3DSA:3.20.20.30
- TIGRFAMs:   TIGR03617

Pfam domain/function: PF00296 Bac_luciferase; SSF51679 Luciferase_like

EC number: NA

Molecular weight: Translated: 37252; Mature: 37121

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGARRLKLDGSIPNQLARAADAAVALERNGFDGGWTAEASHDPFLPLLLAAEHTSRLEL
CCCCEEEEECCCCHHHHHHHHHHHHEEECCCCCCCEECCCCCCCCHHHHEECCCCCCEEC
GTNIAVAFARNPMIVANVGWDLQTYSKGRLILGLGTQIRPHIEKRFSMPWGHPARRMREF
CCCEEEEEECCCEEEEECCCCCEECCCCEEEEECCCCCCHHHHHHCCCCCCCHHHHHHHH
VAALRAIWLAWQDGTKLCFEGEFYTHKIMTPMFTPEPQPYPVPRVFIAAVGEAMTEMCGE
HHHHHHHHHEECCCCEEEEECCEEEHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VADGHLGHPMVSKRYLTEVSVPALLRGLARSGRDRSAFEVSCEVMVATGADDAELAAACT
HHCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCHHHHHHHH
ATRKQIAFYGSTPAYRKVLEQHGWGDLHPELHRLSKLGEWEAMGGLIDDEMLGAFAVVGP
HHHHHEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHCC
VDTIAGALRNRCEGVVDRVLPIFMAASQECINAALQDFRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GGARRLKLDGSIPNQLARAADAAVALERNGFDGGWTAEASHDPFLPLLLAAEHTSRLEL
CCCEEEEECCCCHHHHHHHHHHHHEEECCCCCCCEECCCCCCCCHHHHEECCCCCCEEC
GTNIAVAFARNPMIVANVGWDLQTYSKGRLILGLGTQIRPHIEKRFSMPWGHPARRMREF
CCCEEEEEECCCEEEEECCCCCEECCCCEEEEECCCCCCHHHHHHCCCCCCCHHHHHHHH
VAALRAIWLAWQDGTKLCFEGEFYTHKIMTPMFTPEPQPYPVPRVFIAAVGEAMTEMCGE
HHHHHHHHHEECCCCEEEEECCEEEHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VADGHLGHPMVSKRYLTEVSVPALLRGLARSGRDRSAFEVSCEVMVATGADDAELAAACT
HHCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCHHHHHHHH
ATRKQIAFYGSTPAYRKVLEQHGWGDLHPELHRLSKLGEWEAMGGLIDDEMLGAFAVVGP
HHHHHEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHCC
VDTIAGALRNRCEGVVDRVLPIFMAASQECINAALQDFRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036