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The map label for this gene is 121637290

Identifier: 121637290

GI number: 121637290

Start: 1556687

End: 1557439

Strand: Direct

Name: 121637290

Synonym: BCG_1421

Alternate gene names: NA

Gene position: 1556687-1557439 (Clockwise)

Preceding gene: 121637289

Following gene: 121637291

Centisome position: 35.59

GC content: 62.15

Gene sequence:

>753_bases
ATGTTCATGGCTCTTCGCGCCCCCATGCTTGAGCGCATGAACGGTTTGCATACAGATGACGCGCCGGTCAATTGGCTCGA
GCGGCGAGGTGGCCGGCTTACGTCGAGGCGGAGGGTGACGTTGCTCCATGCTGGAGTGGAACACCCGATGCGGCTGTGGG
GCGTCCAATCCGAGGCGATAACTGCCGCGATGGTGCTTAGCCGGAAGGTATCGGCCATCATTGCCGGACACTGCGGTGTG
CGCCTAGTTGATCAGGGCGTGGGCGATGGCTTCGTCGCCGCGTTCGCCCATGCCAGCGATGCCGTCGCATGTGCTCTGGA
GTTGCACCAGGCTCCGTTGTCCCCGATCGTCCTGCGCATCGGGATTCACACCGGTGAGGCGCAGTTGGTCGACGAGCGCA
TCTACGCCGGCGCCACAATGAACCTGGCTGCAGAGCTACGGGATTTAGCCCATGGTGGGCAGACCGTGATGTCGGGTGCT
ACCGAGGATGCGGTACTCGGCCGGCTTCCCATGCGCGCTTGGCTAATTGGCTTGAGGCCCATGGAAGGGTCCCCGGAAGG
GCATAACTTCCCCCAGTCACAACGCATAGCACAATTGTGCCATCCGAACCTTCGCAACACCTTTCCGCCGCTGCGCATGC
GCATCGCCGATGCGAGCGGAATTCCTTATGTGGGGCGGATTCTGGTTAACGTTCAGGTAGTTCCCCACTGGGAAGGAGGG
TGTGCCGCAGCGGGGATGGTCCTTGCTGGGTGA

Upstream 100 bases:

>100_bases
CGCGCAACACTCGACCTAGGATTGCGCGGCCAGCGCAGGCCCGGAGTTCGAATCGGATGCAATACGCAACCAATCTGGGC
TCTTCTGCGCGTTGTCGCTG

Downstream 100 bases:

>100_bases
AGCGCCATTGAGGGCCAGACGATAGGTTGGCCAGCGACGTCCTCAACTCAGACTCTCGGCGCGACCTGACCGGCGGTTAC
GATCATCTGCTCGGACATTC

Product: putative transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MFMALRAPMLERMNGLHTDDAPVNWLERRGGRLTSRRRVTLLHAGVEHPMRLWGVQSEAITAAMVLSRKVSAIIAGHCGV
RLVDQGVGDGFVAAFAHASDAVACALELHQAPLSPIVLRIGIHTGEAQLVDERIYAGATMNLAAELRDLAHGGQTVMSGA
TEDAVLGRLPMRAWLIGLRPMEGSPEGHNFPQSQRIAQLCHPNLRNTFPPLRMRIADASGIPYVGRILVNVQVVPHWEGG
CAAAGMVLAG

Sequences:

>Translated_250_residues
MFMALRAPMLERMNGLHTDDAPVNWLERRGGRLTSRRRVTLLHAGVEHPMRLWGVQSEAITAAMVLSRKVSAIIAGHCGV
RLVDQGVGDGFVAAFAHASDAVACALELHQAPLSPIVLRIGIHTGEAQLVDERIYAGATMNLAAELRDLAHGGQTVMSGA
TEDAVLGRLPMRAWLIGLRPMEGSPEGHNFPQSQRIAQLCHPNLRNTFPPLRMRIADASGIPYVGRILVNVQVVPHWEGG
CAAAGMVLAG
>Mature_250_residues
MFMALRAPMLERMNGLHTDDAPVNWLERRGGRLTSRRRVTLLHAGVEHPMRLWGVQSEAITAAMVLSRKVSAIIAGHCGV
RLVDQGVGDGFVAAFAHASDAVACALELHQAPLSPIVLRIGIHTGEAQLVDERIYAGATMNLAAELRDLAHGGQTVMSGA
TEDAVLGRLPMRAWLIGLRPMEGSPEGHNFPQSQRIAQLCHPNLRNTFPPLRMRIADASGIPYVGRILVNVQVVPHWEGG
CAAAGMVLAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To class-3 of adenylyl cyclases

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1359_MYCTU (Q11029)

Other databases:

- EMBL:   BX842576
- EMBL:   AE000516
- PIR:   F70741
- RefSeq:   NP_215875.1
- RefSeq:   NP_335852.1
- ProteinModelPortal:   Q11029
- EnsemblBacteria:   EBMYCT00000003308
- EnsemblBacteria:   EBMYCT00000069057
- GeneID:   886841
- GeneID:   924597
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1403
- KEGG:   mtu:Rv1359
- TIGR:   MT1403
- TubercuList:   Rv1359
- GeneTree:   EBGT00050000014809
- HOGENOM:   HBG128140
- OMA:   SPERHNF
- ProtClustDB:   CLSK790812
- InterPro:   IPR001054
- Gene3D:   G3DSA:3.30.70.1230
- SMART:   SM00044

Pfam domain/function: SSF55073 A/G_cyclase

EC number: NA

Molecular weight: Translated: 26887; Mature: 26887

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFMALRAPMLERMNGLHTDDAPVNWLERRGGRLTSRRRVTLLHAGVEHPMRLWGVQSEAI
CCEECCCHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHCCCHHHH
TAAMVLSRKVSAIIAGHCGVRLVDQGVGDGFVAAFAHASDAVACALELHQAPLSPIVLRI
HHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEE
GIHTGEAQLVDERIYAGATMNLAAELRDLAHGGQTVMSGATEDAVLGRLPMRAWLIGLRP
ECCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHCCHHHHHEECCC
MEGSPEGHNFPQSQRIAQLCHPNLRNTFPPLRMRIADASGIPYVGRILVNVQVVPHWEGG
CCCCCCCCCCCHHHHHHHHHCCHHHCCCCCCEEEEECCCCCCEEEEEEEEEEEEECCCCC
CAAAGMVLAG
HHHCCEEECC
>Mature Secondary Structure
MFMALRAPMLERMNGLHTDDAPVNWLERRGGRLTSRRRVTLLHAGVEHPMRLWGVQSEAI
CCEECCCHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHCCCHHHH
TAAMVLSRKVSAIIAGHCGVRLVDQGVGDGFVAAFAHASDAVACALELHQAPLSPIVLRI
HHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEE
GIHTGEAQLVDERIYAGATMNLAAELRDLAHGGQTVMSGATEDAVLGRLPMRAWLIGLRP
ECCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHCCHHHHHEECCC
MEGSPEGHNFPQSQRIAQLCHPNLRNTFPPLRMRIADASGIPYVGRILVNVQVVPHWEGG
CCCCCCCCCCCHHHHHHHHHCCHHHCCCCCCEEEEECCCCCCEEEEEEEEEEEEECCCCC
CAAAGMVLAG
HHHCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036